Left Ventricular Hypertrophy dan Fungsi Ginjal pada Penderita Hipertensi
Introduction: Chronic hypertension can cause complication such as left ventricular <br />hypertrophy (LVH). LVH can lead renal artery vasoconstriction, impaire blood perfusion <br />to glomerulus and change glomerulus filtration coeficient. The aim of this study was to<br />compare kidney function between hypertensive patient with LVH and without LVH<br />Methods: This was a case control study that conducted at Dr. Moewardi General<br />Hospital Surakarta. All subjects has been diagnosed as hypertension more than 5 years.<br />The diagnosis of LVH was based on electrocardiography (ECG) result. Kidney function<br />was assessed based on serum ureum, creatinin, and uric acid levels.<br />Results: The subject of this study was 26 hypertension patients with LVH and 13<br />hypertension patients without LVH. Serum ureum level in patients with LVH was higher<br />than hypertension patients without LVH(24.92 ± 7.99 Vs 32.33±9.91, p= 0.004). Serum<br />uric acid level in hypertension patients with LVH was higher compare to hypertension<br />patients without LVH as well (5.26 ± 1.15 Vs 6.98 ± 1.83, p= 0.029). Whereas serum<br />creatinine levels were not significantly different between two groups of subjects. <br />Sulastomo et.al., Left Ventricular Hypertrophy dan Fungsi Ginjal pada Penderita Hipertensi <br />Conclusion: : Serum ureum and uric acid levels in hypertensive subjects with LVH are<br />higher than subjects without LVH. There is no difference between serum creatinin level in<br />hypertensive subject with LVH and without LVH.<br /><br /><br />