The Role of Olanzapine in the Treatment of Anorexia Nervosa

Interpersonal psychotherapy (IPT) is a focused, time-limited treatment that targets interpersonal problem(s) associated with the onset and/or maintenance of EDs. IPT is supported by substantial empirical evidence documenting the role of interpersonal factors in the onset and maintenance of EDs. IPT is a viable alternative to cognitive behavior therapy for the treatment of bulimia nervosa and binge eating disorder. The effectiveness of IPT for the treatment of anorexia nervosa requires further investigation. The utility of IPT for the prevention of obesity is currently being explored. Future research directions include enhancing the delivery of IPT for EDs, increasing the availability of IPT in routine clinical care settings, exploring IPT adolescent and parent–child adaptations, and developing IPT for the prevention of eating and weight-related problems that may promote full-syndrome EDs or obesity.

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Facilitating Change in Anorexia Nervosa: The Role of Occupational Therapy

British Journal of Occupational Therapy ◽

10.1177/030802269205500903 ◽

1992 ◽

Vol 55 (9) ◽

pp. 334-339 ◽

Cited By ~ 8

Author(s):

Priscilla Harries

Keyword(s):

Anorexia Nervosa ◽

Occupational Therapy ◽

Multidisciplinary Approach ◽

Projective Art

Patients with anorexia nervosa benefit from a multidisciplinary approach. This article gives a brief description of, first, the illness and its treatment and, secondly, the occupational therapy techniques used at the Maudsley Unit. It then demonstrates the progress of patients through examples of projective art.

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Dysfunctional Eating Behaviour and Leptin in Middle-Aged Women: Role of Menopause and a History of Anorexia Nervosa

International Journal of Behavioral Medicine ◽

10.1007/s12529-021-09958-0 ◽

2021 ◽

Author(s):

Suzana Stojiljkovic-Drobnjak ◽

Susanne Fischer ◽

Myrtha Arnold ◽

Wolfgang Langhans ◽

Ulrike Kuebler ◽

...

Keyword(s):

Anorexia Nervosa ◽

Eating Behaviour ◽

Middle Aged ◽

History Of

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Anorexia Nervosa in a Black Zimbabwean

The British Journal of Psychiatry ◽

10.1192/bjp.145.3.326 ◽

1984 ◽

Vol 145 (3) ◽

pp. 326-330 ◽

Cited By ~ 48

Author(s):

T. Buchan ◽

L. D. Gregory

Keyword(s):

Anorexia Nervosa ◽

Special Reference ◽

Diagnostic Criteria ◽

Traditional Healer ◽

Clinical Symptoms ◽

The Social ◽

Speculative Hypothesis ◽

African Patients

SummaryIn spite of the comparative rarity of anorexia nervosa in African patients, the case of a young black Zimbabwean woman which fulfils Feighner's diagnostic criteria is presented. Special reference is made to several unusual features which include the social and psychological conflicts engendered by changes of culture, the clinical symptoms, and the role of a traditional healer in her recovery. A speculative hypothesis concerning aetiology is suggested.

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S.07.01 The role of BDNF in anorexia nervosa and hyperactivity

European Neuropsychopharmacology ◽

10.1016/s0924-977x(05)80613-3 ◽

2005 ◽

Vol 15 ◽

pp. S324

Keyword(s):

Anorexia Nervosa

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Plasma Obestatin, Ghrelin, and Ghrelin/Obestatin Ratio Are Increased in Underweight Patients with Anorexia Nervosa But Not in Symptomatic Patients with Bulimia Nervosa

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2008-1138 ◽

2008 ◽

Vol 93 (11) ◽

pp. 4418-4421 ◽

Cited By ~ 57

Author(s):

Palmiero Monteleone ◽

Cristina Serritella ◽

Vassilis Martiadis ◽

Pasquale Scognamiglio ◽

Mario Maj

Keyword(s):

Anorexia Nervosa ◽

Bulimia Nervosa ◽

Energy Homeostasis ◽

Physiological State ◽

Blood Levels ◽

Women Patients ◽

Underweight Patients ◽

Positive Correlations ◽

Clinical Measures

Introduction: Peptides of the gut-brain axis have a pivotal role in the regulation of energy homeostasis. Obestatin, a sibling of ghrelin derived from preproghrelin, is thought to oppose ghrelin effects on food intake. Because changes in ghrelin levels have been associated with anorexia nervosa (AN) and bulimia nervosa (BN), the investigation of obestatin production may further contribute to understanding the role of peripheral peptides in patients with eating disorders. Methods: In the present study, we measured circulating blood levels of obestatin and ghrelin and assessed their relationships with anthropometric and clinical measures in 20 AN patients, 21 BN patients, and 20 appropriate healthy controls. Results: Compared with healthy women, patients with BN showed no significant differences in plasma obestatin and ghrelin concentrations and in the ghrelin/obestatin ratio, whereas underweight AN patients displayed significantly increased circulating levels of both obestatin (P < 0.009) and ghrelin (P < 0.002) and an increased ghrelin/obestatin ratio (P < 0.04). Moreover, in AN women, positive correlations emerged between the ghrelin/obestatin ratio and current body weight and body mass index. Conclusions: Underweight AN patients are characterized by increased concentrations of ghrelin and obestatin and a higher ghrelin to obestatin ratio. No changes in circulating ghrelin or obestatin as well as in ghrelin to obestatin ratio seem to occur in acutely ill patients with BN. Although those changes likely reflect the physiological state of symptomatic AN individuals, they may also contribute to the pathophysiology of the disorder.

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The Role of Counselling and Self-Help Groups in the Management of Anorexia Nervosa

Current Issues in Clinical Psychology ◽

10.1007/978-1-4613-3721-8_8 ◽

1983 ◽

pp. 73-82

Author(s):

Peter Slade

Keyword(s):

Anorexia Nervosa ◽

Self Help ◽

Self Help Groups

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Family Psychic Transmission and Anorexia Nervosa

Psico-USF ◽

10.1590/1413-82712016210316 ◽

2016 ◽

Vol 21 (3) ◽

pp. 635-649 ◽

Cited By ~ 2

Author(s):

Élide Dezoti Valdanha-Ornelas ◽

Manoel Antônio dos Santos

Keyword(s):

Anorexia Nervosa ◽

Young Woman ◽

Family Relationships ◽

Emotional Development ◽

Female Body ◽

Maternal Grandmother ◽

Three Generations ◽

Mother Daughter Relationship ◽

Mother And Daughter

Abstract Studies show that family relationships can act as mediating agents in triggering and maintaining the symptoms of anorexia nervosa (AN), especially the mother-daughter relationship configuration, which contains unconscious elements transmitted inter-generationally. This study aimed to understand the role of intergenerational psychic transmission in the articulation of anorexic symptoms in a young woman in treatment. Three generations of women of the same family were interviewed: maternal grandmother, mother and daughter, all diagnosed with AN. Some psychic contents that could not be elaborated were identified in the reports and these were, subsequently, converted into legacies transmitted to later generations. Feelings of inhibition and shame regarding sexuality and the female body, transmitted from grandmother to mother and from mother to granddaughter, seem to have blocked the emotional development in all generations. Incorporating these findings into treatment may facilitate the processing of the transmitted unconscious contents, contributing to the reorganization of the family's psychodynamic functioning.

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Gut microbiome dysbiosis in anorexia nervosa

Postępy Higieny i Medycyny Doświadczalnej ◽

10.5604/01.3001.0014.8601 ◽

2021 ◽

Vol 75 ◽

pp. 283-291

Author(s):

Agata Janczy ◽

Magdalena Landowska ◽

Zdzisław Kochan

Keyword(s):

Anorexia Nervosa ◽

Gut Microbiota ◽

Body Mass ◽

Intestinal Microbiota ◽

Gut Microbiome ◽

Dietary Habits ◽

Eating Habits ◽

Current Knowledge ◽

Functional Gastrointestinal Disorders

Anorexia nervosa (AN) is described as an eating disorder, which is characterized by malnutrition, a fear of gaining body mass, and a disturbed self-body image. This disease is dependent on biological, psychological and socio-cultural factors. Among the various biological factors, the importance of intestinal microbiota has recently attracted much attention. Identification of the gut microbiota dysbiosis in patients with AN has opened new and promising research directions. Recent observations focus in particular on the association between intestinal microorganisms and the occurrence of functional gastrointestinal disorders associated with anorexia, anxiety and depression, as well as the regulation of eating habits. The composition of the gut microbiota differs between patients with AN and individuals with normal body mass. This is due to the incorrect diet of patients; on the other hand, there is growing interest in the role of intestinal microbiota in the pathogenesis of AN, its changes through re-nutrition practices, and in particular the modulation of intestinal microbiological composition by means of nutritional interventions or the use of preand probiotics as standard supplements therapy of eating disorders. There is a need for further research about the microbiome - intestine - brain axis. Furthermore, consequences of changes in dietary habits as part of AN treatment are also unknown. However, better knowledge about the relationship between the gut microbiome and the brain can help improve the treatment of this disorder. This review aims to present the current knowledge about the potential role of intestinal microbiota in the pathogenesis, course and treatment of AN.

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