Caffeic Acid Phenethyl Ester Causes p21Cip1 Induction, Akt Signaling Reduction, and Growth Inhibition in PC-3 Human Prostate Cancer Cells

Hui-Ping Lin; Shih Sheng Jiang; Chih-Pin Chuu

doi:10.1371/journal.pone.0031286

Caffeic Acid Phenethyl Ester Causes p21Cip1 Induction, Akt Signaling Reduction, and Growth Inhibition in PC-3 Human Prostate Cancer Cells

PLoS ONE ◽

10.1371/journal.pone.0031286 ◽

2012 ◽

Vol 7 (2) ◽

pp. e31286 ◽

Cited By ~ 51

Author(s):

Hui-Ping Lin ◽

Shih Sheng Jiang ◽

Chih-Pin Chuu

Keyword(s):

Prostate Cancer ◽

Growth Inhibition ◽

Cancer Cells ◽

Caffeic Acid ◽

Caffeic Acid Phenethyl Ester ◽

Akt Signaling ◽

Human Prostate ◽

Human Prostate Cancer ◽

Prostate Cancer Cells

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Caffeic Acid Phenethyl Ester Suppresses the Proliferation of Human Prostate Cancer Cells through Inhibition of p70S6K and Akt Signaling Networks

Cancer Prevention Research ◽

10.1158/1940-6207.capr-12-0004-t ◽

2012 ◽

Vol 5 (5) ◽

pp. 788-797 ◽

Cited By ~ 64

Author(s):

Chih-Pin Chuu ◽

Hui-Ping Lin ◽

Mark F. Ciaccio ◽

John M. Kokontis ◽

Ronald J. Hause ◽

...

Keyword(s):

Prostate Cancer ◽

Cancer Cells ◽

Caffeic Acid ◽

Caffeic Acid Phenethyl Ester ◽

Akt Signaling ◽

Human Prostate ◽

Signaling Networks ◽

Human Prostate Cancer ◽

Prostate Cancer Cells

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p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition

Journal of Experimental & Clinical Cancer Research ◽

10.1186/s13046-019-1267-z ◽

2019 ◽

Vol 38 (1) ◽

Cited By ~ 2

Author(s):

Monika Aggarwal ◽

Rahul Saxena ◽

Nasir Asif ◽

Elizabeth Sinclair ◽

Judy Tan ◽

...

Keyword(s):

Prostate Cancer ◽

Growth Inhibition ◽

Cancer Cells ◽

Human Prostate ◽

Phenethyl Isothiocyanate ◽

Human Prostate Cancer ◽

Prostate Cancer Cells ◽

Mutant Type

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Androgen signaling is required for the vitamin D-mediated growth inhibition in human prostate cancer cells

Oncogene ◽

10.1038/sj.onc.1207461 ◽

2004 ◽

Vol 23 (19) ◽

pp. 3350-3360 ◽

Cited By ~ 43

Author(s):

Bo-Ying Bao ◽

Yueh-Chiang Hu ◽

Huei-Ju Ting ◽

Yi-Fen Lee

Keyword(s):

Prostate Cancer ◽

Vitamin D ◽

Growth Inhibition ◽

Cancer Cells ◽

Human Prostate ◽

Human Prostate Cancer ◽

Prostate Cancer Cells

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Role of insulin-like growth factor binding proteins in 1α,25-dihydroxyvitamin D3-induced growth inhibition of human prostate cancer cells

The Prostate ◽

10.1002/pros.20212 ◽

2005 ◽

Vol 64 (1) ◽

pp. 9-19 ◽

Cited By ~ 23

Author(s):

LaMonica V. Stewart ◽

Nancy L. Weigel

Keyword(s):

Prostate Cancer ◽

Growth Factor ◽

Growth Inhibition ◽

Cancer Cells ◽

Binding Proteins ◽

Human Prostate ◽

Human Prostate Cancer ◽

Prostate Cancer Cells ◽

Dihydroxyvitamin D3

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Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1

Oncotarget ◽

10.18632/oncotarget.3246 ◽

2015 ◽

Vol 6 (9) ◽

pp. 6684-6707 ◽

Cited By ~ 37

Author(s):

Hui-Ping Lin ◽

Ching-Yu Lin ◽

Chieh Huo ◽

Ping-Hsuan Hsiao ◽

Liang-Cheng Su ◽

...

Keyword(s):

Prostate Cancer ◽

Cell Cycle ◽

Growth Inhibition ◽

Cell Cycle Arrest ◽

Cancer Cells ◽

Caffeic Acid ◽

Caffeic Acid Phenethyl Ester ◽

Prostate Cancer Cells ◽

Cycle Arrest ◽

Androgen Independent

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Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells

Cancer Biology & Therapy ◽

10.4161/cbt.9.2.10422 ◽

2010 ◽

Vol 9 (2) ◽

pp. 142-152 ◽

Cited By ~ 55

Author(s):

Uma K. Misra ◽

Salvatore V. Pizzo

Keyword(s):

Prostate Cancer ◽

Cell Surface ◽

Cancer Cells ◽

Akt Signaling ◽

Human Prostate ◽

Human Prostate Cancer ◽

Caspase Activation ◽

Prostate Cancer Cells ◽

Terminal Domain ◽

Cell Surface Grp78

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Induction of retinol-binding protein 4 and placenta-specific 8 expression in human prostate cancer cells remaining in bone following osteolytic tumor growth inhibition by osteoprotegerin

International Journal of Oncology ◽

10.3892/ijo.2013.1954 ◽

2013 ◽

Vol 43 (2) ◽

pp. 365-374 ◽

Cited By ~ 11

Author(s):

HISANORI UEHARA ◽

TETSUYUKI TAKAHASHI ◽

KEISUKE IZUMI

Keyword(s):

Prostate Cancer ◽

Tumor Growth ◽

Growth Inhibition ◽

Cancer Cells ◽

Retinol Binding Protein ◽

Human Prostate ◽

Tumor Growth Inhibition ◽

Human Prostate Cancer ◽

Prostate Cancer Cells ◽

Retinol Binding Protein 4

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Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells

Journal of Cellular Biochemistry ◽

10.1002/jcb.22098 ◽

2009 ◽

Vol 106 (6) ◽

pp. 1113-1122 ◽

Cited By ~ 71

Author(s):

Dae-Hee Lee ◽

Miroslaw-Jerzy Szczepanski ◽

Yong J. Lee

Keyword(s):

Prostate Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Akt Signaling ◽

Human Prostate ◽

Human Prostate Cancer ◽

Akt Signaling Pathway ◽

Prostate Cancer Cells

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S179D prolactin sensitizes human prostate cancer cells such that physiological concentrations of 1, 25 dihydroxy vitamin D3 result in growth inhibition and cell death

The Prostate ◽

10.1002/pros.20598 ◽

2007 ◽

Vol 67 (14) ◽

pp. 1498-1506 ◽

Cited By ~ 7

Author(s):

Wei Wu ◽

Laura Zanello ◽

Ameae M. Walker

Keyword(s):

Prostate Cancer ◽

Cell Death ◽

Growth Inhibition ◽

Cancer Cells ◽

Vitamin D3 ◽

Human Prostate ◽

Human Prostate Cancer ◽

Prostate Cancer Cells

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The combination of gamma ionizing radiation and 8-Cl-cAMP induces synergistic cell growth inhibition and induction of apoptosis in human prostate cancer cells

Investigational New Drugs ◽

10.1007/s10637-007-9101-4 ◽

2007 ◽

Vol 26 (4) ◽

pp. 309-317 ◽

Cited By ~ 8

Author(s):

Vesna Vučić ◽

Ana Nićiforović ◽

Miroslav Adžić ◽

Marija B. Radojčić ◽

Sabera Ruždijić

Keyword(s):

Prostate Cancer ◽

Cell Growth ◽

Ionizing Radiation ◽

Growth Inhibition ◽

Cancer Cells ◽

Human Prostate ◽

Human Prostate Cancer ◽

Cell Growth Inhibition ◽

Prostate Cancer Cells ◽

Induction Of Apoptosis

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