scholarly journals Bone Morphogenetic Protein 6 Polymorphisms Are Associated with Radiographic Progression in Ankylosing Spondylitis

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e104966 ◽  
Author(s):  
Young Bin Joo ◽  
So-Young Bang ◽  
Tae-Hwan Kim ◽  
Seung-Cheol Shim ◽  
Seunghun Lee ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Bone Morphogenetic Protein ◽  
Radiographic Progression ◽  
Morphogenetic Protein ◽  
Bone Morphogenetic Protein 6

scholarly journals Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice

Blood ◽  
2017 ◽  
Vol 129 (4) ◽  
pp. 405-414 ◽  
Author(s):  
Susanna Canali ◽  
Kimberly B. Zumbrennen-Bullough ◽  
Amanda B. Core ◽  
Chia-Yu Wang ◽  
Manfred Nairz ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Bone Morphogenetic Protein ◽  
Knockout Mice ◽  
Iron Homeostasis ◽  
Conditional Knockout ◽  
Conditional Knockout Mice ◽  
Morphogenetic Protein ◽  
Key Points ◽  
Paracrine Actions ◽  
Bone Morphogenetic Protein 6

Key Points Endothelial Bmp6 conditional knockout mice exhibit hemochromatosis, whereas hepatocyte and macrophage Bmp6 conditional knockout mice do not. Our data support a model in which EC Bmp6 has paracrine actions on hepatocyte hemojuvelin to regulate hepcidin production.

scholarly journals Novel mutations in the bone morphogenetic protein 6 gene in patients with iron overload and non-homozygous genotype for the HFE p.Cys282Tyr mutation

2020 ◽  
Vol 84 ◽  
pp. 102444
Author(s):  
Aline Morgan Alvarenga ◽  
Nathália Kozikas da Silva ◽  
Paula Fernanda Silva Fonseca ◽  
Theo G.M. Oliveira ◽  
Jacilene Barbosa da Silva Monteiro ◽  
...  
Keyword(s):  
Iron Overload ◽  
Bone Morphogenetic Protein ◽  
Novel Mutations ◽  
Morphogenetic Protein ◽  
Homozygous Genotype ◽  
Bone Morphogenetic Protein 6
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