scholarly journals Associations between cognitive performance and sigma power during sleep in children with attention-deficit/hyperactivity disorder, healthy children, and healthy adults

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0224166 ◽  
Author(s):  
Arnika Bestmann ◽  
Annette Conzelmann ◽  
Lioba Baving ◽  
Alexander Prehn-Kristensen
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Cognitive Performance ◽  
Attention Deficit ◽  
Healthy Adults ◽  
Healthy Children ◽  
Hyperactivity Disorder

scholarly journals DRD4 Gene Polymorphisms as a Risk Factor for Children with Attention Deficit Hyperactivity Disorder in Iranian Population

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Seyed Mahmoud Tabatabaei ◽  
Shahrokh Amiri ◽  
Sara Faghfouri ◽  
Seyed Gholamreza Noorazar ◽  
Shahin AbdollahiFakhim ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Tandem Repeats ◽  
Receptor Gene ◽  
Variable Number ◽  
Healthy Children ◽  
Drd4 Gene ◽  
Hyperactivity Disorder ◽  
Significant Difference ◽  
Northwest Of Iran

Background and Objective. Dopamine dysfunction is known to be associated with attention deficit hyperactivity disorder (ADHD). Dopamine D4 receptor gene (DRD4) is one of the important genes in this pathway. This study intended to investigate the variable number of tandem repeats (VNTR) in exon 3 of the DRD4 gene in Iranian children and adolescents. Materials and Methods. In this study, 130 children with ADHD, aged 6–14 years, and 130 healthy children, within the same age range, were enrolled. All children were selected from northwest of Iran which have Caucasian ethnic background and are of a Turkic ethnic group. VNTR polymorphisms of the DRD4 gene were evaluated by PCR using exon 3-specific primers followed by agarose gel electrophoresis. Findings. The Hardy-Weinberg principle and Chi-square test showed a significant difference in 4-repetition (4R) alleles between the ADHD (76.2%) and control (53.8%) groups (p=0.004; X2=17.39; df=5). The least percentage of repetition alleles in both groups was 2R. Conclusion. There is a significant correlation between the 4R alleles of DRD4 and ADHD in the northwest of Iran.

Resting EEG theta activity predicts cognitive performance in attention-deficit hyperactivity disorder

2005 ◽  
Vol 32 (4) ◽  
pp. 248-256 ◽  
Author(s):  
Daniel F. Hermens ◽  
Eleonore X.C. Soei ◽  
Simon D. Clarke ◽  
Michael R. Kohn ◽  
Evian Gordon ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Cognitive Performance ◽  
Attention Deficit ◽  
Theta Activity ◽  
Hyperactivity Disorder

scholarly journals Serum Levels of Vitamin A and Vitamin D and Their Association With Symptoms in Children With Attention Deficit Hyperactivity Disorder

2020 ◽  
Vol 11 ◽  
Author(s):  
Hong-Hua Li ◽  
Xiao-Jing Yue ◽  
Cheng-Xin Wang ◽  
Jun-Yan Feng ◽  
Bing Wang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Attention Deficit Hyperactivity Disorder ◽  
Vitamin A ◽  
Attention Deficit ◽  
Serum Levels ◽  
Adhd Group ◽  
Healthy Children ◽  
Serum Concentrations ◽  
Children With Adhd ◽  
Hyperactivity Disorder

Objective: To measure levels of vitamin A (VA) and vitamin D (VD) and the symptomatic association of their co-deficiencies on attention deficit hyperactivity disorder (ADHD) in Chinese children (6–9 years).Methods: Eighty-two children (69 boys and 13 girls; mean age = 7.1 ± 0.9 years at the time of the diagnosis) with ADHD were recruited as ADHD group. A total of 106 healthy children were recruited as the healthy control (HC) group. Serum levels of retinol and 25-hydroxyvitamin D (25(OH)D) of all children were evaluated using high-performance liquid chromatography (HPLC) and HPLC-tandem mass spectrometry. The Swanson, Nolan, and Pelham IV Rating Scale (SNAP-IV) was employed to assess the clinical symptoms of ADHD.Results: Children suffering from ADHD had significantly reduced serum levels of retinol and 25(OH)D compared with those of HCs, and the prevalence of VA deficiency and VD deficiency were higher in children suffering from ADHD. Serum concentrations of 25(OH)D and retinol were linked closely with the presence or absence of ADHD after adjustment for age, body mass index, season of blood sampling, and sun exposure. Serum concentrations of 25(OH)D and retinol showed a negative correlation with the total scores of SNAP-IV. Children with ADHD as well as VA and VD co-deficiency had increased SNAP-IV total scores and ADHD inattention subscale scores.Conclusion: VA deficiency and VD deficiency in children with ADHD were increased in comparison with that in HCs. VA and VD co-deficiency associated with ADHD symptom severity. Attention should be paid to regular testing of VA levels and VD levels. However, the mechanism of VA and VD in ADHD needs to be further studied. Interventional studies on VA and VD supplementation are recommended to further verify the relationship between VA and VD co-deficiency and ADHD.

Relation between resting EEG to cognitive performance and clinical symptoms in adults with attention-deficit/hyperactivity disorder

2010 ◽  
Vol 469 (1) ◽  
pp. 102-106 ◽  
Author(s):  
Martine van Dongen-Boomsma ◽  
Marieke M. Lansbergen ◽  
Evelijne M. Bekker ◽  
J.J. Sandra Kooij ◽  
Maurits van der Molen ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Cognitive Performance ◽  
Attention Deficit ◽  
Clinical Symptoms ◽  
Hyperactivity Disorder

scholarly journals Differential motor alterations in children with three types of attention deficit hyperactivity disorder

2014 ◽  
Vol 72 (11) ◽  
pp. 856-861 ◽  
Author(s):  
Adrián Poblano ◽  
Belinda Luna ◽  
César Reynoso
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Motor Skills ◽  
Attention Deficit ◽  
Healthy Children ◽  
Age And Gender ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Hand Coordination ◽  
And Gender ◽  
Motor Alterations

Objective To determine frequency of motor alterations in children with attention deficit hyperactivity disorder (ADHD). Method We evaluated 19 children aged 7-12 years with ADHD classified in three sub-types: Combined (ADHD-C), with Inattention (ADHD-I), and with Hyperactivity (ADHD-H). Controls were age- and gender matched healthy children. We utilized Bruininks-Oseretsky Test of Motor Proficiency (BOTMP) for measuring motor skills. Results We observed differences between children with ADHD and controls in BOTMP general score and in static coordination, dynamic general- and hand- coordination, and in synkinetic movements. We also found differences in dynamic hand coordination between controls and children with ADHD-C; in dynamic general coordination between controls and children with ADHD-H; and in frequency of synkinetic movements between controls and children with ADHD-H. Conclusion Children with ADHD with a major degree of hyperactivity showed greater frequency of motor alterations.

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