scholarly journals Comparison of methods for texture analysis of QUS parametric images in the characterization of breast lesions

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0244965
Author(s):  
Laurentius O. Osapoetra ◽  
William Chan ◽  
William Tran ◽  
Michael C. Kolios ◽  
Gregory J. Czarnota

Purpose Accurate and timely diagnosis of breast carcinoma is very crucial because of its high incidence and high morbidity. Screening can improve overall prognosis by detecting the disease early. Biopsy remains as the gold standard for pathological confirmation of malignancy and tumour grading. The development of diagnostic imaging techniques as an alternative for the rapid and accurate characterization of breast masses is necessitated. Quantitative ultrasound (QUS) spectroscopy is a modality well suited for this purpose. This study was carried out to evaluate different texture analysis methods applied on QUS spectral parametric images for the characterization of breast lesions. Methods Parametric images of mid-band-fit (MBF), spectral-slope (SS), spectral-intercept (SI), average scatterer diameter (ASD), and average acoustic concentration (AAC) were determined using QUS spectroscopy from 193 patients with breast lesions. Texture methods were used to quantify heterogeneities of the parametric images. Three statistical-based approaches for texture analysis that include Gray Level Co-occurrence Matrix (GLCM), Gray Level Run-length Matrix (GRLM), and Gray Level Size Zone Matrix (GLSZM) methods were evaluated. QUS and texture-parameters were determined from both tumour core and a 5-mm tumour margin and were used in comparison to histopathological analysis in order to classify breast lesions as either benign or malignant. We developed a diagnostic model using different classification algorithms including linear discriminant analysis (LDA), k-nearest neighbours (KNN), support vector machine with radial basis function kernel (SVM-RBF), and an artificial neural network (ANN). Model performance was evaluated using leave-one-out cross-validation (LOOCV) and hold-out validation. Results Classifier performances ranged from 73% to 91% in terms of accuracy dependent on tumour margin inclusion and classifier methodology. Utilizing information from tumour core alone, the ANN achieved the best classification performance of 93% sensitivity, 88% specificity, 91% accuracy, 0.95 AUC using QUS parameters and their GLSZM texture features. Conclusions A QUS-based framework and texture analysis methods enabled classification of breast lesions with >90% accuracy. The results suggest that optimizing method for extracting discriminative textural features from QUS spectral parametric images can improve classification performance. Evaluation of the proposed technique on a larger cohort of patients with proper validation technique demonstrated the robustness and generalization of the approach.

Author(s):  
Mona E. Elbashier ◽  
Suhaib Alameen ◽  
Caroline Edward Ayad ◽  
Mohamed E. M. Gar-Elnabi

This study concern to characterize the pancreas areato head, body and tail using Gray Level Run Length Matrix (GLRLM) and extract classification features from CT images. The GLRLM techniques included eleven’s features. To find the gray level distribution in CT images it complements the GLRLM features extracted from CT images with runs of gray level in pixels and estimate the size distribution of thesubpatterns. analyzing the image with Interactive Data Language IDL software to measure the grey level distribution of images. The results show that the Gray Level Run Length Matrix and  features give classification accuracy of pancreashead 89.2%, body 93.6 and the tail classification accuracy 93.5%. The overall classification accuracy of pancreas area 92.0%.These relationships are stored in a Texture Dictionary that can be later used to automatically annotate new CT images with the appropriate pancreas area names.


Entropy ◽  
2019 ◽  
Vol 21 (2) ◽  
pp. 145 ◽  
Author(s):  
Viet Tra ◽  
Bach-Phi Duong ◽  
Jae-Young Kim ◽  
Muhammad Sohaib ◽  
Jong-Myon Kim

This paper proposes a reliable fault diagnosis model for a spherical storage tank. The proposed method first used a blind source separation (BSS) technique to de-noise the input signals so that the signals acquired from a spherical tank under two types of conditions (i.e., normal and crack conditions) were easily distinguishable. BSS split the signals into different sources that provided information about the noise and useful components of the signals. Therefore, an unimpaired signal could be restored from the useful components. From the de-noised signals, wavelet-based fault features, i.e., the relative energy (REWPN) and entropy (EWPN) of a wavelet packet node, were extracted. Finally, these features were used to train one-against-all multiclass support vector machines (OAA MCSVMs), which classified the instances of normal and faulty states of the tank. The efficiency of the proposed fault diagnosis model was examined by visualizing the de-noised signals obtained from the BSS method and its classification performance. The proposed fault diagnostic model was also compared to existing techniques. Experimental results showed that the proposed method outperformed conventional techniques, yielding average classification accuracies of 97.25% and 98.48% for the two datasets used in this study.


2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Mohamed Abdel-Nasser ◽  
Jaime Melendez ◽  
Antonio Moreno ◽  
Domenec Puig

Texture analysis methods are widely used to characterize breast masses in mammograms. Texture gives information about the spatial arrangement of the intensities in the region of interest. This information has been used in mammogram analysis applications such as mass detection, mass classification, and breast density estimation. In this paper, we study the effect of factors such as pixel resolution, integration scale, preprocessing, and feature normalization on the performance of those texture methods for mass classification. The classification performance was assessed considering linear and nonlinear support vector machine classifiers. To find the best combination among the studied factors, we used three approaches: greedy, sequential forward selection (SFS), and exhaustive search. On the basis of our study, we conclude that the factors studied affect the performance of texture methods, so the best combination of these factors should be determined to achieve the best performance with each texture method. SFS can be an appropriate way to approach the factor combination problem because it is less computationally intensive than the other methods.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Kun Sun ◽  
Zhicheng Jiao ◽  
Hong Zhu ◽  
Weimin Chai ◽  
Xu Yan ◽  
...  

Abstract Background This study aimed to evaluate the utility of radiomics-based machine learning analysis with multiparametric DWI and to compare the diagnostic performance of radiomics features and mean diffusion metrics in the characterization of breast lesions. Methods This retrospective study included 542 lesions from February 2018 to November 2018. One hundred radiomics features were computed from mono-exponential (ME), biexponential (BE), stretched exponential (SE), and diffusion-kurtosis imaging (DKI). Radiomics-based analysis was performed by comparing four classifiers, including random forest (RF), principal component analysis (PCA), L1 regularization (L1R), and support vector machine (SVM). These four classifiers were trained on a training set with 271 patients via ten-fold cross-validation and tested on an independent testing set with 271 patients. The diagnostic performance of the mean diffusion metrics of ME (mADCall b, mADC0–1000), BE (mD, mD*, mf), SE (mDDC, mα), and DKI (mK, mD) were also calculated for comparison. The area under the receiver operating characteristic curve (AUC) was used to compare the diagnostic performance. Results RF attained higher AUCs than L1R, PCA and SVM. The AUCs of radiomics features for the differential diagnosis of breast lesions ranged from 0.80 (BE_D*) to 0.85 (BE_D). The AUCs of the mean diffusion metrics ranged from 0.54 (BE_mf) to 0.79 (ME_mADC0–1000). There were significant differences in the AUCs between the mean values of all diffusion metrics and radiomics features of AUCs (all P < 0.001) for the differentiation of benign and malignant breast lesions. Of the radiomics features computed, the most important sequence was BE_D (AUC: 0.85), and the most important feature was FO-10 percentile (Feature Importance: 0.04). Conclusions The radiomics-based analysis of multiparametric DWI by RF enables better differentiation of benign and malignant breast lesions than the mean diffusion metrics.


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