scholarly journals A three-dimensional intestinal tissue model reveals factors and small regulatory RNAs important for colonization with Campylobacter jejuni

2020 ◽  
Vol 16 (2) ◽  
pp. e1008304 ◽  
Author(s):  
Mona Alzheimer ◽  
Sarah L. Svensson ◽  
Fabian König ◽  
Matthias Schweinlin ◽  
Marco Metzger ◽  
...  
Keyword(s):  
Campylobacter Jejuni ◽  
Three Dimensional ◽  
Intestinal Tissue ◽  
Tissue Model ◽  
Small Regulatory Rnas ◽  
Regulatory Rnas

scholarly journals Development of a human neuromuscular tissue-on-a-chip model on a 24-well-plate-format compartmentalized microfluidic device

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Kazuki Yamamoto ◽  
Nao Yamaoka ◽  
Yu Imaizumi ◽  
Takunori Nagashima ◽  
Taiki Furutani ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Microfluidic Device ◽  
Motor Neurons ◽  
Muscle Fibers ◽  
Three Dimensional ◽  
Tissue Model ◽  
Skeletal Muscle Fibers

A three-dimensional human neuromuscular tissue model that mimics the physically separated structures of motor neurons and skeletal muscle fibers is presented.

Recent Research Advances in Small Regulatory RNAs in Streptococcus

2021 ◽  
Author(s):  
Zhi-Qiang Xiong ◽  
Ze-Xuan Lv ◽  
Xin Song ◽  
Xin-Xin Liu ◽  
Yong-Jun Xia ◽  
...  
Keyword(s):  
Small Regulatory Rnas ◽  
Regulatory Rnas

scholarly journals Extensive Analysis of miRNA Trimming and Tailing Indicates that AGO1 Has a Complex Role in miRNA Turnover

Plants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 267
Author(s):  
Axel J. Giudicatti ◽  
Ariel H. Tomassi ◽  
Pablo A. Manavella ◽  
Agustin L. Arce
Keyword(s):  
Small Rna ◽  
Stress Responses ◽  
Cellular Localization ◽  
Mirna Biogenesis ◽  
Small Rna Sequencing ◽  
Sequencing Data ◽  
Extensive Analysis ◽  
Small Regulatory Rnas ◽  
Regulatory Rnas ◽  
Argonaute 1

MicroRNAs are small regulatory RNAs involved in several processes in plants ranging from development and stress responses to defense against pathogens. In order to accomplish their molecular functions, miRNAs are methylated and loaded into one ARGONAUTE (AGO) protein, commonly known as AGO1, to stabilize and protect the molecule and to assemble a functional RNA-induced silencing complex (RISC). A specific machinery controls miRNA turnover to ensure the silencing release of targeted-genes in given circumstances. The trimming and tailing of miRNAs are fundamental modifications related to their turnover and, hence, to their action. In order to gain a better understanding of these modifications, we analyzed Arabidopsis thaliana small RNA sequencing data from a diversity of mutants, related to miRNA biogenesis, action, and turnover, and from different cellular fractions and immunoprecipitations. Besides confirming the effects of known players in these pathways, we found increased trimming and tailing in miRNA biogenesis mutants. More importantly, our analysis allowed us to reveal the importance of ARGONAUTE 1 (AGO1) loading, slicing activity, and cellular localization in trimming and tailing of miRNAs.

Application of combined three-dimensional bone and soft tissue model

1998 ◽  
Vol 27 (6) ◽  
pp. 482-484 ◽  
Author(s):  
Gert Santler ◽  
Hans Kaercher ◽  
Alexander Gaggl ◽  
Guenter Schultes
Keyword(s):  
Soft Tissue ◽  
Three Dimensional ◽  
Tissue Model

scholarly journals An Interplay Between Small Regulatory RNAs Patterns Leaves

2007 ◽  
Vol 2 (6) ◽  
pp. 519-521 ◽  
Author(s):  
Fabio T.S. Nogueira ◽  
Marja C.P. Timmermans
Keyword(s):  
Small Regulatory Rnas ◽  
Regulatory Rnas

Evaluation of photodynamic therapy efficiency using an in vitro three-dimensional microfluidic breast cancer tissue model

Lab on a Chip ◽  
2015 ◽  
Vol 15 (3) ◽  
pp. 735-744 ◽  
Author(s):  
Yamin Yang ◽  
Xiaochuan Yang ◽  
Jin Zou ◽  
Chao Jia ◽  
Yue Hu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Photodynamic Therapy ◽  
Three Dimensional ◽  
Therapeutic Agents ◽  
Breast Cancer Tissue ◽  
Cancer Tissue ◽  
Tissue Model

A microfluidic-based in vitro three-dimensional (3D) breast cancer tissue model was established for determining the efficiency of photodynamic therapy (PDT) with therapeutic agents (photosensitizer and gold nanoparticles) under various irradiation conditions.

Three-dimensional tissue model in direct contact with an on-chip vascular bed enabled by removable membranes

Lab on a Chip ◽  
2022 ◽  
Author(s):  
Yoshikazu Kameda ◽  
Surachada Chuaychob ◽  
Miwa Tanaka ◽  
Yang Liu ◽  
Ryu Okada ◽  
...  
Keyword(s):  
Tissue Culture ◽  
Direct Contact ◽  
Three Dimensional ◽  
Culture Period ◽  
Tissue Model ◽  
Vascular Bed ◽  
On Chip

Three-dimensional (3D) tissue culture is a powerful tool for understanding physiological events. However, 3D tissues still have limitations in their size, culture period, and maturity, which are caused by the...

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