Compliance with Surgical After-care following Bariatric Surgery for Morbid Obesity: a Retrospective Study

Abstract Background Bariatric surgery is effective for the treatment of patients with morbid obesity and type 2 diabetes mellitus (T2DM), for body weight loss and glycemic control. However, in Japan, there has been no previous report of the effectiveness bariatric surgery in a case of morbid obesity associated with acute onset type 1 diabetes mellitus (T1DM), in which pancreatic β-cells were destroyed and endogenous insulin was depleted. Case presentation A 36-year-old woman with morbid obesity and T1DM, diagnosed when she was 6 years, was admitted for bariatric surgery. At her first consultation, she had a body weight of 106.7 kg and a body mass index of 42.2 kg/m2. Her HbA1c level was 9.0%, with a required daily insulin dose of 75 units. She underwent laparoscopic sleeve gastrectomy. At 1 year after surgery, her body weight had decreased to 81.0 kg and her body mass index to 32.2 kg/m2. In addition, her daily required dose of insulin had decreased to 24 units, with an improvement in her HbA1c level to 7.7%. Conclusions Although further evidence needs to be accumulated, including long-term outcomes, laparoscopic sleeve gastrectomy may provide an effective treatment for patients with morbid obesity and T1DM for body weight loss, improvement in HbA1c level, and insulin dose reduction.

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Associations between Pre-Bariatric High-Sensitivity C-Reactive Protein and Post-Surgery Outcomes

Diagnostics ◽

10.3390/diagnostics11040721 ◽

2021 ◽

Vol 11 (4) ◽

pp. 721

Author(s):

Tannaz Jamialahmadi ◽

Mohsen Nematy ◽

Simona Bo ◽

Valentina Ponzo ◽

Ali Jangjoo ◽

...

Keyword(s):

Bariatric Surgery ◽

Morbid Obesity ◽

Weight Loss ◽

Success Rate ◽

Liver Stiffness ◽

High Sensitivity ◽

C Reactive Protein ◽

Reactive Protein ◽

Post Surgery ◽

Hs Crp

Background: Obesity is a chronic inflammatory condition associated with increased circulating levels of C-reactive protein (CRP). Bariatric surgery has been reported to be effective in improving both inflammatory and liver status. Our aims were to elucidate the relationships between pre-surgery high sensitivity-CRP (hs-CRP) values and post-surgery weight loss and liver steatosis and fibrosis in patients with severe obesity undergoing Roux-en-Y gastric bypass. Methods: We conducted an observational prospective study on 90 individuals with morbid obesity, who underwent gastric bypass. Anthropometric indices, laboratory assessment (lipid panel, glycemic status, liver enzymes, and hs-CRP), liver stiffness and steatosis were evaluated at baseline and 6-months after surgery. Results: There was a significant post-surgery reduction in all the anthropometric variables, with an average weight loss of 33.93 ± 11.79 kg; the mean percentage of total weight loss (TWL) was 27.96 ± 6.43%. Liver elasticity was significantly reduced (from 6.1 ± 1.25 to 5.42 ± 1.52 kPa; p = 0.002), as well as liver aminotransferases, nonalcoholic fatty liver disease fibrosis score (NFS) and the grade of steatosis. Serum hs-CRP levels significantly reduced (from 9.26 ± 8.45 to 3.29 ± 4.41 mg/L; p < 0.001). The correlations between hs-CRP levels and liver fibrosis (elastography), steatosis (ultrasonography), fibrosis-4 index, NFS, and surgery success rate were not significant. Regression analyses showed that serum hs-CRP levels were not predictive of liver status and success rate after surgery in both unadjusted and adjusted models. Conclusions: In patients with morbid obesity, bariatric surgery caused a significant decrease in hs-CRP levels, liver stiffness and steatosis. Baseline hs-CRP values did not predict the weight-loss success rate and post-surgery liver status.

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Bariatric surgery in the treatment of patients with obesity and type 1 diabetes: A retrospective study of clinical data

Diabetes Obesity and Metabolism ◽

10.1111/dom.14369 ◽

2021 ◽

Author(s):

Nagi Mohammed ◽

Adam Buckley ◽

Mohgah Elsheikh ◽

Matthew Allum ◽

Sara Suliman ◽

...

Keyword(s):

Bariatric Surgery ◽

Type 1 Diabetes ◽

Retrospective Study ◽

Clinical Data

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Impact of body mass index on immunogenicity of hepatitis B vaccine in bariatric surgery candidates: A retrospective study

Diabetes & Metabolic Syndrome Clinical Research & Reviews ◽

10.1016/j.dsx.2021.102254 ◽

2021 ◽

Vol 15 (5) ◽

pp. 102254

Author(s):

Ali Kabir ◽

Samaneh Lotfi ◽

Farnaz Farsi ◽

Abdolreza Pazouki

Keyword(s):

Bariatric Surgery ◽

Body Mass Index ◽

Retrospective Study ◽

Hepatitis B ◽

Body Mass ◽

Hepatitis B Vaccine

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Bariatric Surgery and Long-term Control of Morbid Obesity

JAMA ◽

10.1001/jama.288.22.2793 ◽

2002 ◽

Vol 288 (22) ◽

pp. 2793 ◽

Cited By ~ 308

Author(s):

Robert E. Brolin

Keyword(s):

Bariatric Surgery ◽

Morbid Obesity

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Bariatric Surgery in Adults: Patient Workup and Preparation

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2020/v32i1130526 ◽

2020 ◽

pp. 8-14

Author(s):

Ravi Kant ◽

Shankar Roy ◽

Pradeep Yadav KL ◽

Monika Pathania

Keyword(s):

Risk Factors ◽

Metabolic Disease ◽

Bariatric Surgery ◽

Metabolic Syndrome ◽

Morbid Obesity ◽

Life Style ◽

Point Of View ◽

Related Complication ◽

Initial Intervention ◽

Work Up

With the advancement and industrialization of our society, the prevalence of metabolic disease is also increasing. Among the risk factors for metabolic syndrome and many other non-communicable diseases, obesity is the single most important one. Although life style and pharmacological therapies are the part of initial intervention, however once the overt obesity related complication appears, bariatric surgery becomes the only curative intervention. Various modalities surgeries have come into place in recent times. However preparing a patient physically and mentally needs a thorough pre- operative preparation. Here in this review, we are exploring the approach to patient with morbid obesity and work up for bariatric surgery from a physician’s point of view.

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An analysis of the objective and subjective evaluation of the results of surgical treatment of morbid obesity

Obesity and metabolism ◽

10.14341/omet2015326-30 ◽

2015 ◽

Vol 12 (3) ◽

pp. 26-30

Author(s):

Valeriy Nikolaevich Egiev ◽

Yuliya Borisovna Mayorova ◽

Evgeniy Aleksandrovich Zorin ◽

Anastasiya Vladimirovna Мелеshko ◽

Ekaterina Sergeevna Orlovskaya

Keyword(s):

Bariatric Surgery ◽

Morbid Obesity ◽

Body Weight ◽

Surgical Treatment ◽

Treatment Effectiveness ◽

Minimum Weight ◽

Subjective Evaluation ◽

Objective Assessment ◽

Subjective Assessment ◽

Excess Body Weight

The results of surgical treatment of morbid obesity usually considers a variety of factors and the main attention is paid to the dynamics of body weight after surgery. It is generally accepted that in the absence of reducing excess body weight or with minimum weight loss (a few kilograms), the result is considered unsatisfactory. The aim of the work was to compare an objective assessment of gastric bypass (GBS) and gastric banding (GB) and the subjective evaluation of treatment effectiveness by patients themselves. The study included 457 (69.7%) patients that underwent GB and 198 (30.3%) patients after GBS. At the late postoperative period 243 patients (53.2%) were available after the GB and 112 (56.6%) patients after GBS. The frequency of matches between objective and subjective assessment of outcomes of surgery usually did not exceed 50%. Given this, there is a need for a comprehensive analysis of the results of bariatric surgery. Developed multicomponent scale allows to evaluate the effectiveness of any bariatric surgery.

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