Physical Inactivity is a Risk Factor for Lower Extremity Arterial Disease and Coronary Heart Disease

2005 ◽  
pp. 85-98
Author(s):  
Dennis G. Caralis ◽  
Stamatis Dimitropoulos
Keyword(s):  
Coronary Heart Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Lower Extremity ◽  
Physical Inactivity ◽  
Arterial Disease ◽  
Lower Extremity Arterial Disease

Are predictors of coronary heart disease and lower-extremity arterial disease in type 1 diabetes the same?

2000 ◽  
Vol 148 (1) ◽  
pp. 159-169 ◽  
Author(s):  
Kimberly Y.-Z Forrest ◽  
Dorothy J Becker ◽  
Lewis H Kuller ◽  
Sidney K Wolfson ◽  
Trevor J Orchard
Keyword(s):  
Coronary Heart Disease ◽  
Type 1 Diabetes ◽  
Heart Disease ◽  
Lower Extremity ◽  
Arterial Disease ◽  
Lower Extremity Arterial Disease

scholarly journals Alcohol Consumption Is a Risk Factor for Lower Extremity Arterial Disease in Chinese Patients with T2DM

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Shanshan Yang ◽  
Shuang Wang ◽  
Bo Yang ◽  
Jinliang Zheng ◽  
Yuping Cai ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Risk Factor ◽  
Alcohol Consumption ◽  
Lower Extremity ◽  
Logistic Regression Analysis ◽  
Arterial Disease ◽  
Hospitalized Patients ◽  
Chinese Patients ◽  
Lower Extremity Arterial Disease

Objective. To investigate the relationship between alcohol consumption and diabetic lower extremity arterial disease (LEAD) in hospitalized patients with type 2 diabetes mellitus (T2DM). Methods. We evaluated 138 hospitalized patients with T2DM who consumed alcohol and 833 who did not. We used propensity score matching to reduce the confounding bias between groups. Additionally, a logistic regression analysis was performed with the matched data to evaluate the LEAD risk. Results. In total, 119 pairs of patients who did and did not consume alcohol were matched. According to the logistic regression analysis, patients who consumed >8 U of alcohol/day had a higher risk of LEAD (odds ratio (OR): 6.35, 95% confidence interval (CI): 1.78–22.65) than patients who did not consume alcohol. Additionally, after adjusting for age, gender, region, occupation, smoking status, body mass index, weight change, and duration of diabetes, the OR of peripheral artery disease after >20 years of alcohol consumption was 3.48 (95% CI: 1.09–11.15). Furthermore, we observed a significant dose-response relationship between alcohol consumption and LEAD. Conclusions. Alcohol consumption may be a risk factor of LEAD in patients with T2DM. Patients with T2DM should be advised to stop drinking, to prevent the onset of LEAD.

scholarly journals Lower Extremity Peripheral Arterial Disease Is an Independent Predictor of Coronary Heart Disease and Stroke Risks in Patients with Type 2 Diabetes Mellitus in China

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Xiao-Hong Pang ◽  
Jue Han ◽  
Wan-Lan Ye ◽  
Xue Sun ◽  
Yue Ding ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Lower Extremity ◽  
Stroke Risk ◽  
Independent Predictor ◽  
Arterial Disease ◽  
Chd Risk ◽  
Peripheral Arterial

We aimed to determine the relationship between lower extremity peripheral arterial disease (PAD), 10-year coronary heart disease (CHD), and stroke risks in patients with type 2 diabetes (T2DM) using the UKPDS risk engine. We enrolled 1178 hospitalized T2DM patients. The patients were divided into a lower extremity PAD group (ankle-brachial index≤0.9 or >1.4; 88 patients, 7.5%) and a non-PAD group (ankle-brachial index>0.9 and ≤1.4; 1090 patients, 92.5%). Age; duration of diabetes; systolic blood pressure; the hypertension rate; the use of hypertension drugs, ACEI /ARB, and statins; CHD risk; fatal CHD risk; stroke risk; and fatal stroke risk were significantly higher in the PAD group than in the non-PAD group (P<0.05 for all). Logistic stepwise regression analysis indicated that ABI was an independent predictor of 10-year CHD and stroke risks in T2DM patients. Compared with those in the T2DM non-PAD group, the odds ratios (ORs) for CHD and stroke risk were 3.6 (95% confidence interval (CI), 2.2–6.0; P<0.001) and 6.9 (95% CI, 4.0–11.8; P<0.001) in those with lower extremity PAD, respectively. In conclusion, lower extremity PAD increased coronary heart disease and stroke risks in T2DM.

Insulin resistance—a risk factor for coronary heart disease?

1983 ◽  
Vol 43 (8) ◽  
pp. 677-685 ◽  
Author(s):  
P. Garcia-Webb ◽  
A. M. Bonser ◽  
D. Whiting ◽  
J. R. L. Masarei
Keyword(s):  
Insulin Resistance ◽  
Coronary Heart Disease ◽  
Risk Factor ◽  
Heart Disease

EVALUATION OF RISK FACTOR CHRONIC OCCLUSIVE ARTERIAL DISEASE OF LOWER EXTREMITY

2012 ◽  
pp. 16-21
Author(s):  
Quang Thuu Le
Keyword(s):  
Risk Factor ◽  
Lower Extremity ◽  
Cholesterol Level ◽  
Cardiovascular Surgery ◽  
Arterial Disease ◽  
High Cholesterol ◽  
Severe Condition ◽  
Occlusive Arterial Disease ◽  
High Cholesterol Level ◽  
Centre Hospital

Objectives: We research risk factors of chronic occlusive arterial disease of lower extremity. Subjects and methods: From 05/2010 to 04/2012, prospective study at Department of Thoracic and Cardiovascular Surgery of Hue Centre hospital, we have performed 49 patients in 30 males and 19 females from 33 to 92 ages, who were treated chronic occlusive arterial disease of lower extremity. Results: Majority of patients came to hospital with severe condition in grade III and IV according to Leriche-Fontain standards (27.12% and 66.1%). All patients incomed, expect the unmodifiable risk factor (as age, sex), we found socialty risk factor remarable (as hypertension 51.1%, smoking 18.36%, diabetes 10.2%, high cholesterol level 4.08%. Conclusions: Expect the unmodifiable risk factor, we found a the most striking association with hypertension, smoking, diabetes, high cholesterol level.

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