New technologies applied to canine limb prostheses: A review

Although only a few studies have investigated about the development of animal prosthesis, currently, there is an increasing interest in canine limb prosthesis design and its clinical application since they offer an alternative to killing the animal in extreme situations where amputating the limb is the only option. Restoring normal function of amputated canine limbs with the use of a prosthesis is challenging. However, recent advances in surgical procedures and prosthesis design technology appear promising in developing devices that closely recreate normal canine limb function. Surgical advances such as evolution of osseointegration (bone-anchored) prostheses present great promise. Likewise, modern computer-aided design and manufacturing technology, as well as novel motion analysis systems are now providing improved prosthesis designs. Advances in patient-customized prostheses have the potential to reduce the risk of implant failure. The objective of this investigation is to present a general review of the existing literature on modern surgical approaches, design and manufacturing methods, as well as biomechanical analyses so that veterinarians can make more and better-informed decisions on the development and selection of proper canine limb prosthesis. Isolated research efforts have made possible an improvement in stability, comfort, and performance of canine limb prosthesis. However, continued multidisciplinary research collaboration and teamwork among veterinarians, engineers, designers, and industry, with supporting scientific evidence, is required to better understand the development of canine limb prosthesis designs that closely replicate the normal limb function.

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3D Foot Scan to Custom Shoe Last

International Journal of Computer and Communication Technology ◽

10.47893/ijcct.2010.1030 ◽

2010 ◽

pp. 110-114

Author(s):

Nibedita Rout ◽

Asimananda Khandual ◽

Yi Fan Zhang ◽

Ameersing Luximon

Keyword(s):

Computer Aided Design ◽

New Technologies ◽

Rapid Development ◽

New Techniques ◽

Shoe Last ◽

Computer Aided ◽

Design And Manufacturing ◽

Best Fitting ◽

Manufacturing Technologies ◽

Aided Design

Today’s customers not only look at aesthetic beauty but also quality, comfort and fit. New technologies such as digitization and virtual 3D tailoring are providing more options to consumers and designers in designing different styles with the least possible time. Next to the shoe fashion and style, good fit and comfort are the second important determinant in the purchase of footwear. Although there is a need for better fitting, there are no techniques for fit quantification. In traditional shoemaking, the shoe is categorized by the length and width (or girth), hence there is always a mismatch between the complex foot shape and shoe shape. For the industry in order to meet the demand for better footwear, new techniques for fit quantification is required in order to have a direct mapping form foot to shoe-last (a mold for making shoes). In recent years, with the rapid development of computer technology and advanced design and manufacturing technologies such as computer-aided design (CAD) and computer-aided manufacturing (CAM), the manufacturing of customized shoe lasts is becoming possible. Still research is needed to find the best shoe-last. This paper discusses the basic concepts and current methods being followed to convert foot to shoe-last, retrieve the best fitting shoe last based on the 3D foot scan of the customer, and to obtain customized shoe last.

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Design and manufacture of 3D cell culture plate for mass production of cell-spheroids

Scientific Reports ◽

10.1038/s41598-019-50186-0 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 3

Author(s):

Dongkyoung Lee ◽

Shiva Pathak ◽

Jee-Heon Jeong

Keyword(s):

Stem Cells ◽

Cell Culture ◽

Mesenchymal Stem Cells ◽

Mass Production ◽

Computer Aided Design ◽

3D Cell Culture ◽

Great Promise ◽

Cell Spheroids ◽

Culture Plate ◽

Design And Manufacturing

Abstract A 3D cell culture is preferred to 2D cell culture since it allows cells to grow in all directions in vitro, similar to how they would in vivo. 3D cell culture plates currently used in tissue engineering research have limited access to control the geometry. Furthermore, 3D cell culture plate manufacturing methods are relatively complex, time-consuming, labor-intensive, and expensive. Therefore, a design and manufacturing method, which has relatively low cost, high throughput, and high size flexibility, is proposed. Cell culture plate was fabricated by computer aided design and manufacturing software using polydimethylsiloxane as a plate constituent. With the successfully-developed 3D cell culture plate, the morphology and viability of the cultured mesenchymal stem cells were tested.The mesenchymal stem cells seeded on the newly-fabricated 3D cell culture plate aggregated to form 3D spheroids within 24 h of incubation and well-maintained their viability. Thus, due to the capacity of mass production of the cell spheroids with a desired cell viability, the newly-fabricated plate has a great promise to prepare 3D cell spheroids for experimental as well as clinical applications.

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Computer Aided Design and Manufacturing of Soft, Three-Dimensional, Multilayer, Biological Constructs via Laser Printing onto Laser Machined Composite Biopapers

Journal of Imaging Science and Technology ◽

10.2352/j.imagingsci.technol.2014.58.2.040402 ◽

2014 ◽

Keyword(s):

Computer Aided Design ◽

Three Dimensional ◽

Laser Printing ◽

Computer Aided ◽

Design And Manufacturing ◽

Aided Design

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The Application of Computer Techniques in the Design and Manufacturing of Timing Scrolls

Proceedings of the Institution of Mechanical Engineers Part E Journal of Process Mechanical Engineering ◽

10.1243/pime_proc_1993_207_213_02 ◽

1993 ◽

Vol 207 (2) ◽

pp. 99-108

Author(s):

L Q Tang ◽

D N Moreton

Keyword(s):

Dynamic Characteristic ◽

Computer Aided Design ◽

Numerical Control ◽

Feeding Mechanism ◽

Control Techniques ◽

Computer Aided ◽

Design And Manufacturing ◽

Manufacturing Techniques ◽

Aided Design ◽

Design And Manufacture

The timing scroll is an important feeding mechanism on packaging lines. As packaging line speeds have increased and the shape of containers has become more diverse, the techniques used for the design and manufacture of such timing scrolls have become critical for successful packaging line performance. Since 1980, various techniques have evolved to improve scroll design, manufacture and the associated line performance. In recent years, as CAD (computer aided design), CAM (computer aided manufacture) and CNC (computer numerical control) techniques have evolved, scroll design and manufacturing techniques began to be linked with computer techniques. In this paper, a scroll design and manufacturing package is presented which can be run on a minicomputer, such as a μ-VAX on an IBM PC clone. This scroll package can produce a timing scroll for any type of container with a correct pocket shape and good dynamic characteristic. Tests using carefully chosen containers have been made using this package and the results indicate that the scrolls obtained by this package have the correct pocket shape and good line performance. However, the design of a good pick-up geometry for some container shapes remains a problem.

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