scholarly journals Congenital Arteriovenous Malformation of Lip - A Case Report

2021 ◽  
Vol 10 (30) ◽  
pp. 2354-2357
Author(s):  
Rajasbala Pradeep Dhande ◽  
Megha Manoj ◽  
Roohi Gupta ◽  
Prerna Patwa ◽  
Prasanthi Ghanta
Keyword(s):  
Arteriovenous Malformation ◽  
Vascular Malformations ◽  
Venous Malformation ◽  
The Body ◽  
Vascular Anomalies ◽  
Surrounding Tissue ◽  
Signal Process ◽  
Vascular Neoplasms ◽  
Congenital Arteriovenous Malformation ◽  
Av Malformation

Vascular anomalies are a heterogeneous group of lesions involving vascular channels including the lymphatics. They encompass a wide variety of lesions from simple capillary haemangiomas to angiosarcomas. These lesions most commonly occur as a result of developmental error during embryogenesis due to defective signal process.1 Most of these lesions occur sporadically while a few may be inherited or acquired. Inherited lesions tend to be small and multi-centric which gradually increase its size with age.2 The International Society for the Study of Vascular Anomalies has broadly classified vascular anomalies into 2 groups: 1) Vascular neoplasms and 2) Vascular malformations.3 Vascular malformations are a relatively rare group of lesions involving the endothelium and surrounding tissue of arteries and veins resulting in an abnormal arteriovenous shunting. They are categorised into 4 types: 1) Venous malformation, 2) Capillary malformation, 3) Arteriovenous malformation and 4) Lymphatic malformation. They can occur anywhere in the body from head to toe, but they are most commonly seen in the brain. The most common extra-cranial site for AV malformations is the head and neck and other common sites include limbs, trunk and viscera.4 Here, we a present a rare case of congenital AV malformation of lip in a 49-year-old male.

scholarly journals Sirolimus for the treatment of vascular anomalies in children

2020 ◽  
Vol 7 (3) ◽  
pp. 22-31
Author(s):  
E. K. Donyush ◽  
Z. A. Kondrashova ◽  
Yu. A. Polyaev ◽  
R. V. Garbuzov
Keyword(s):  
Vascular Malformations ◽  
Venous Malformation ◽  
Antiangiogenic Therapy ◽  
Pneumocystis Pneumonia ◽  
Response To Therapy ◽  
Vascular Anomalies ◽  
Vascular Tumors ◽  
Treatment Regimens ◽  
Transplant Patients ◽  
Results Of Treatment

Vascular anomalies (VA) comprise a heterogeneous group of diseases associated with congenital angiogenesis disorder. There are no currently developed unified protocols and treatment regimens for systemic forms of VA. Numerous advantages show sirolimus, an mTOR inhibitor, as a well tolerated and effective antiproliferative and antiangiogenic therapy in patients with VA. The article presents the results of treatment of 211 patients with VA (6 patients with vascular tumors and 205 patients with vascular malformations) aged 2 months to 17 years (median – 9 years), who received sirolimus therapy for 1–86 months (median – 24 months). Sirolimus was administered at a starting dose of 0.8 mg/m2/day orally in two doses with an interval of 12 hours. The concentration of the blood preparation was maintained in the therapeutic range of 6–15 ng/ml. Since 2015, concomitant therapy with co-trimoxazole for the prevention of Pneumocystis pneumonia has been prescribed only to tracheostomy carriers. When infectious episodes occurred in patients, sirolimus therapy continued without changes in the dose of the drug and did not affect the disease, provided that the therapeutic concentration was maintained. A positive response to therapy was observed in 89.1 % of patients with VA in the form of the size of the vascular mass according to the data of visual examination and instrumental control. All patients showeda clinical response to therapy in the form of relief of painsyndrome, reduction/relief of lymphorrhea, reduction/improvement of hemostasis parameters, and an increase in functional activity and quality. For the entire observation period 2012–2020, when taking sirolimus, not a single severe adverse event occurring in post-transplant patients has been reported that would require discontinuation of the drug. The article presents two clinical cases of sirolimus use in the treatment of patients with kaposiform hemangioendothelioma and extensive venous malformation. Parents are encouraged to use the information in scientific research and publications.

scholarly journals Vascular malformations: a hospital based study

2019 ◽  
Vol 7 (8) ◽  
pp. 2936
Author(s):  
Komanapalli Sunilkumar ◽  
Karthik Aithal ◽  
Unmesh Kumar Jena ◽  
Uma Prasad ◽  
Bhagyalakshmi Atla ◽  
...  
Keyword(s):  
Vascular Malformations ◽  
Tertiary Care ◽  
Vascular Anomalies ◽  
Imaging Features ◽  
Venous Malformations ◽  
Internal Elastic Lamina ◽  
Tertiary Care Centre ◽  
Vascular Neoplasms ◽  
Diagnostic Difficulties ◽  
Appropriate Therapy

Background: Vascular anomalies comprise a widely heterogeneous group of lesions. Diagnosis and management of these lesions present challenges to the surgeons, radiologists and histopathologists. Accurate classification of these lesions results in appropriate therapy. Aim of the study is to study the role of histopathology and histochemical stain in the diagnosis of vascular malformationMethods: The present study is a hospital based observational study on vascular malformations over a period of three years from 2016 to 2018 done in department of Pathology and Plastic Surgery at tertiary care centre, Visakhapatnam.Results: Out of 107 specimens of vascular anomalies received, 72 cases were vascular neoplasms, 35 were vascular malformations. Majority of the vascular malformations were seen in the cervicofacial region (43%) followed by extremities (37.1%). Most common malformation in the present study was arterio venous malformations (60%) followed by venous malformations (22.8%). Verhoeff’s VanGieson stain demonstrated discontinuity of internal elastic lamina in cases of arteriovenous malformation and helped in differentiating the lesions from capillary malformation and vascular tumors.Conclusions: Histopathology, special histochemical stains along with imaging features can be used to reduce diagnostic difficulties and in helping proper management of vascular malformations.

Intraoral Venous Malformation-A Case report

2021 ◽  
pp. 80-82
Author(s):  
B.V Subhash ◽  
Alba Dinesh ◽  
Seema Patil ◽  
Asha R Iyengar ◽  
Revan Kumar Joshi ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Vascular Malformations ◽  
Venous Malformation ◽  
Vascular Anomalies ◽  
Venous Malformations ◽  
Wide Spread ◽  
Facial Area ◽  
Ct And Mri

The vascular anomalies consist of vascular tumours and vascular malformations. One among these are the venous malformations which constitute about 40% of all vascular malformations. Usually, the venous malformations present as localized lesions in the form of swellings/nodules with phleboliths, are diagnosed by ultrasonography, CT and MRI. Summary: This is a report of a rare longstanding case of wide spread venous malformations of oral cavity and facial area with phleboliths.

Association of venous and true arteriovenous malformation: a rare entity among mixed vascular malformations of the brain

1995 ◽  
Vol 83 (1) ◽  
pp. 141-144 ◽  
Author(s):  
Bernhard Meyer ◽  
Armin P. Stangl ◽  
Johannes Schramm
Keyword(s):  
Arteriovenous Malformation ◽  
Vascular Malformations ◽  
Venous Malformation ◽  
Rare Entity ◽  
Venous Malformations ◽  
Content Type ◽  
Hemorrhagic Infarction ◽  
The Brain ◽  
Cerebrovascular Malformation ◽  
Fine Print

✓ In this article the authors report the case of a mixed cerebrovascular malformation in which a true arteriovenous malformation (AVM), harboring a nidus, is associated with a venous malformation that serves as the draining vein for the nidus. Despite the authors' preoperative rationale for exclusive extirpation of the AVM, an inadvertent injury and the obliteration of the venous malformation generated delayed postoperative neurological deterioration, which could clearly be attributed to venous hemorrhagic infarction. Because this is only the second instance of this type of mixed vascular malformation of the brain reported, which also underscores the concept of nonsurgical treatment of venous malformations, the authors discuss the diverse literature regarding mixed vascular malformations and the treatment of venous malformations.

Congenital Vascular Malformations: General Diagnostic Principles

2007 ◽  
Vol 22 (6) ◽  
pp. 253-257 ◽  
Author(s):  
B B Lee ◽  
J Laredo ◽  
S J Lee ◽  
S H Huh ◽  
J H Joe ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Arteriovenous Malformation ◽  
Vascular Malformation ◽  
Vascular Malformations ◽  
Venous Malformation ◽  
Secondary Effects ◽  
Non Invasive ◽  
Congenital Vascular Malformation ◽  
Work Up ◽  
Single Lesion

Venous malformation (VM) is the most common congenital vascular malformation (CVM), which usually presents as a single lesion in the majority of cases. It also presents as a mixed lesion combined with other CVMs (e.g. lymphatic malformation and arteriovenous malformation [AVM]). Therefore, the diagnosis of VM should include an appropriate work-up, to not only confirm and characterize the VM as either extratruncular or truncular but also to diagnose or exclude the presence of other CVMs. The diagnosis of VM can be made safely using non-invasive to minimally invasive studies, which can also distinguish VM from infantile haemangioma. Invasive studies, such as venography and arteriography, are generally reserved for therapeutic planning and diagnosis of more virulent CVMs (e.g. AVM). The work-up of VM should include a complete assessment of the extent and severity of the primary VM lesion. In addition, its embryologic origin, as well as its haemodynamic characteristics and secondary effects should also be determined.

scholarly journals A Case of Arteriovenous Malformation of the Nasal Tip

2020 ◽  
Vol 63 (3) ◽  
pp. 123-128
Author(s):  
Yangseop Noh ◽  
Gwanghui Ryu ◽  
Hyo Yeol Kim
Keyword(s):  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Treatment Plan ◽  
Venous Malformation ◽  
Successful Outcome ◽  
Nasal Tip ◽  
Appropriate Treatment ◽  
Superselective Embolization ◽  
Fast Flow

Arteriovenous malformation is a vascular malformation with fast-flow shunt from the artery to the vein. Extracranial arteriovenous malformation in the head and neck area is rare disease compared to other vascular malformations such as venous malformation or lymphatic malformation. Extracranial arteriovenous malformations especially on face can cause aesthetic problems, therefore surgeons should consider an importance of cosmetic outcome and choose appropriate treatment plan. We report a case of 51-year-old male who presented with enlarged nasal tip diagnosed arteriovenous malformation. This case showed successful outcome after combination therapy consisted of superselective embolization and surgical resection.

Epidural spinal cord compression in a patient with blue rubber bleb nevus syndrome

2014 ◽  
Vol 14 (5) ◽  
pp. 486-489 ◽  
Author(s):  
Gary Rajah ◽  
Chiu Yuen To ◽  
Sandeep Sood ◽  
Steven Ham ◽  
Deniz Altinok ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Vascular Malformations ◽  
Present Report ◽  
Pediatric Population ◽  
Venous Malformation ◽  
Cord Compression ◽  
The Body ◽  
Early Age ◽  
Myxoid Degeneration

Blue rubber bleb nevus syndrome (BRBNS) can present with vascular malformations throughout the body, especially in the gastrointestinal tract. Spinal cord compression from these lesions is rare, particularly in the pediatric population. The authors report a case of BRBNS involving an 18-year-old female patient who presented with back pain and an epidural thoracic mass with cord compression. She underwent an uncomplicated thoracic laminectomy and decompression, with removal of what appeared to be a venous malformation. Postoperatively her pain improved, and imaging revealed resolution of cord compression. Pathological analysis highlighted dilated venous channels with myxoid degeneration in the wall with clot, characteristic of BRBNS. The early age of presentation and location are unique based on the literature search of BRBNS. The present report highlights the multiplicity of venous malformations in BRBNS, and the management of this case.

scholarly journals The use of interstitial echo-guided diode laser 980-nm for deep vascular anomalies in pediatric patients: a preliminary study

2013 ◽  
Vol 3 (1) ◽  
pp. 2 ◽  
Author(s):  
Luigino Santecchia ◽  
Maria Francesca Bianciardi Valassina ◽  
Guido Ciprandi ◽  
Rodolfo Fruhwirth ◽  
Mario Zama
Keyword(s):  
Diode Laser ◽  
Pediatric Patients ◽  
Vascular Malformations ◽  
The Body ◽  
Vascular Anomalies ◽  
Low Flow ◽  
Mass Reduction ◽  
Wide Range ◽  
Preliminary Study ◽  
Magnetic Resonance Imaging Mri

A wide range of therapeutic options is available to treat vascular anomalies, arising from the systemic therapies to surgery or using lasers. The purpose of this preliminary study is to assess the effectiveness of treatment of vascular anomalies anywhere in the body, along with the use of interstitial echo-guided 980 nm diode laser. The analysis occurs through accurate angio magnetic resonance imaging (MRI) pre- and post-treatment measurements. We enrolled all the patients (16) affected on vascular malformations everywhere in the body, treated from January to August 2012. We obtained excellent results in 6 patients (37.5%) with mean mass reduction of 85%, good in 9 patients (56%) with mean mass reduction of 65% and unsatisfactory in 1 patient (6%). In pediatric patients, low-flow vascular malformations resistant to progressive sclerotherapy or in critical anatomical sites, benefit of echo guided interstitial 980-nm diode laser.

scholarly journals Ultrasonographic and Imaging Appearance of Peripheral Intraneural Vascular Anomalies: Report of Two Cases and Review of the Literature.

2018 ◽  
Vol 20 (2) ◽  
pp. 237
Author(s):  
Georgeta Mihaela Rusu ◽  
Constantin Ciuce ◽  
Lucian Fodor ◽  
Simona Manole ◽  
Sorin Marian Dudea
Keyword(s):  
Median Nerve ◽  
Peripheral Nerves ◽  
Clinical Presentation ◽  
Vascular Malformations ◽  
Venous Malformation ◽  
Vascular Anomalies ◽  
Compartment Syndromes ◽  
Imaging Appearance ◽  
First Choice ◽  
Ultrasonographic Appearance

The purpose of the paper is to present the ultrasonographic and imaging appearance of two cases of peripheral nerve intraneural vascular anomalies and provide a comprehensive review of the publications on this subject.The clinical presentation, ultrasonographic appearance, corresponding imaging and outcome of a case of ulnar nerve venous malformation and a case of median nerve arteriovenous malformation are presented.Literature search revealed 35 papers presenting 52 cases of vascular anomalies involving the peripheral nerves. The ultrasonographic appearance was described only in ten cases. Our review suggests that peripheral intraneural vascular anomalies are twice more frequent in women. About three quarters of them are located in the upper limb, with the median nerve involved in one third and the ulnar nerved involved in a quarter of all cases. Most of the cases are hemangiomas. Peripheral neural compartment syndromes in patients with coexisting vascular anomalies may prompt for vascular neural involvement, requiring diagnostic imaging studies. Gray-scale and Doppler ultrasound are the methods of first choice, as they provide not only direct visual proof of neural involvement but also contribute to the differential diagnosis between hemangiomas and vascular malformations.

scholarly journals Vascular endothelial cell specification in health and disease

Angiogenesis ◽  
2021 ◽  
Author(s):  
Corina Marziano ◽  
Gael Genet ◽  
Karen K. Hirschi
Keyword(s):  
Endothelial Cells ◽  
Endothelial Cell ◽  
Current Knowledge ◽  
Vascular Malformations ◽  
Immune Surveillance ◽  
Vascular Endothelial Cell ◽  
Lymphatic Vessels ◽  
Lymphatic Endothelial Cell ◽  
The Body ◽  
Vascular Networks

AbstractThere are two vascular networks in mammals that coordinately function as the main supply and drainage systems of the body. The blood vasculature carries oxygen, nutrients, circulating cells, and soluble factors to and from every tissue. The lymphatic vasculature maintains interstitial fluid homeostasis, transports hematopoietic cells for immune surveillance, and absorbs fat from the gastrointestinal tract. These vascular systems consist of highly organized networks of specialized vessels including arteries, veins, capillaries, and lymphatic vessels that exhibit different structures and cellular composition enabling distinct functions. All vessels are composed of an inner layer of endothelial cells that are in direct contact with the circulating fluid; therefore, they are the first responders to circulating factors. However, endothelial cells are not homogenous; rather, they are a heterogenous population of specialized cells perfectly designed for the physiological demands of the vessel they constitute. This review provides an overview of the current knowledge of the specification of arterial, venous, capillary, and lymphatic endothelial cell identities during vascular development. We also discuss how the dysregulation of these processes can lead to vascular malformations, and therapeutic approaches that have been developed for their treatment.

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