scholarly journals An analysis of the demographic profile, clinical manifestations, investigations and outcome of paediatric myelodysplastic syndrome: A single centre, cross-sectional study

2015 ◽  
Vol 3 (3) ◽  
pp. 337
Author(s):  
Appaji Lingegowda ◽  
Lakshmaiah Kuntegowdenahalli
Keyword(s):  
Myelodysplastic Syndrome ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Single Centre ◽  
Cross Sectional ◽  
Demographic Profile

Etiologies, Clinical Manifestations, and Factors Associated with Severe Symptomatic Hyponatremia among Hospitalized Hyponatremia Patients

2020 ◽  
Vol 103 (5) ◽  
pp. 465-471
Keyword(s):  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Hospitalized Patients ◽  
Sectional Study ◽  
Close Attention ◽  
Cross Sectional ◽  
Factors Associated ◽  
Present Cross Sectional Study ◽  
Important Health ◽  
Baseline Characteristics

Background: Hyponatremia is associated with unfavorable outcomes in many cases. The mainstay of hyponatremia treatment depends on its symptoms and etiology. However, etiologies, clinical manifestations, and factors associated with severe symptomatic hyponatremia have been rarely reported. Objective: To analyze and report etiologies, clinical manifestations, and factors associated with severe symptomatic hyponatremia. Materials and Methods: In the present cross-sectional study, the authors enrolled hospitalized patients with hyponatremia who had consulted a nephrologist between October 1, 2017, and October 31, 2018. Their baseline characteristics and clinical manifestations were recorded. Etiologies were confirmed by the attending nephrology staff. Factors associated with severe symptomatic hyponatremia were evaluated using logistic regression analysis. Results: One hundred patients were included in this study. The syndrome of inappropriate antidiuresis (SIAD), hypovolemia, and hydrochlorothiazide use were the leading hyponatremia etiologies. Hyponatremia etiologies differed between patients with community-acquired hyponatremia (n=50) and those with hospital-associated hyponatremia (n=50). Patients with communityacquired hyponatremia were older, presented with a higher frequency of severe symptomatic hyponatremia, and showed lower SNa-levels. Low SNa-levels were significantly associated with severe symptomatic hyponatremia (p=0.014). Conclusion: Hyponatremia remains an important health problem. SIAD, hypovolemia, and hydrochlorothiazide use are among the leading etiologies of hyponatremia. Low SNa-levels are associated with severe symptomatic hyponatremia; thus, physicians should pay close attention to low SNa-levels in hospitalized patients. Keywords: Hyponatremia, Symptomatic Hyponatremia, Community-acquired hyponatremia, Hospital-associated hyponatremia

scholarly journals Antiphospholipid antibodies and neurological manifestations in acute COVID-19: A single-centre cross-sectional study

2021 ◽  
pp. 101070
Author(s):  
Laura A. Benjamin ◽  
Ross W. Paterson ◽  
Rachel Moll ◽  
Charis Pericleous ◽  
Rachel Brown ◽  
...  
Keyword(s):  
Antiphospholipid Antibodies ◽  
Cross Sectional Study ◽  
Neurological Manifestations ◽  
Sectional Study ◽  
Single Centre ◽  
Cross Sectional

A Cross-Sectional Study of Myelodysplastic Syndrome in a Brazilian Population

2017 ◽  
Vol 17 ◽  
pp. S347-S348
Author(s):  
Glaciano Ribeiro ◽  
Gustavo Santos ◽  
Warlenn Silva ◽  
Gabriel Diniz ◽  
Fabiana Piassi ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Cross Sectional Study ◽  
Brazilian Population ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals A cross sectional study of elderly widows residing in urban field practice area of S. N. Medical College, Bagalkot, Karnataka

2018 ◽  
Vol 5 (12) ◽  
pp. 5224
Author(s):  
Gowri Shankar ◽  
Jayaraj M. Ramachandra ◽  
Sarojini S. Hunshikatti
Keyword(s):  
Cause Of Death ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sitting Posture ◽  
Demographic Profile ◽  
Medical College ◽  
Field Practice

Background: Widows are the most vulnerable segment among the elderly population in India. Elderly widows face several social, economic, emotional and cultural deprivations due to their gender, widowhood and old age. Hence, this study was done with the objective to know the socio demographic profile and morbidity of elderly widows residing in urban field practice area of S.N. Medical College, Bagalkot.Methods: This cross sectional study was done in 8 Anganwadi areas during 2016 by cluster random sampling. All the elderly widows residing in the areas were included after informed consent. Ethical clearance was obtained from Institutional review board. Data regarding their socio demographic profile, cause of death of husband, the number of years being a widow, health seeking behavior and their chronic morbidities were noted. Height and weight of each elderly widow was measured and body mass index calculated using the formula weight in kilogram divided by height in meter 2 and classified according to South East Asian category. Blood pressure was recorded three times with the widow in a sitting posture in an interval of 3 minutes and the least value was documented according to JNU classification.Results: Out of 140 elderly widows who were residents of the areas, majority (69.29%) were between 60 to 74 years of age followed by 27.86% between 75 to 89 years of age. It was observed that 75% of them were illiterate. The leading cause of death of husband was coronary heart disease (19.29%), chronic obstructive pulmonary disease (12.86%) and alcoholic cirrhosis (10.71%). On examination of the non-hypertensive widows, it was observed that 36.06% were in Stage I and 22.68% were in Stage II of hypertension (JNU classification).Conclusions: Elderly widows are a vulnerable segment of the community. Their health care needs are a priority and regular health check-ups are to be planned.

scholarly journals ABDOMINAL VERSUS VAGINAL HYSTERECTOMY;

2008 ◽  
Vol 15 (04) ◽  
pp. 486-491
Author(s):  
MUHAMMAD IKRAM ◽  
ZOONA SAEED ◽  
ROOHI SAEED ◽  
Uhammad Saeed
Keyword(s):  
Vaginal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Audit Report ◽  
Single Centre ◽  
Cross Sectional ◽  
Main Indication ◽  
Operative Complication

Objective: To evaluate abdominal versus vaginal hysterectomy in relation to operative and post operative complications.Design: Single centre cross sectional study. Place and duration: The Department of Obstetric and Gynaecology, Shaikh Zayed post graduateMedical institute and Hospital, Lahore from 1 November 2005 to 31 October 2006. Subject and methods: All the patients with benign st stindications for hysterectomy (abdominal and vaginal) were included except patients with serious / complicated medical disease. Relativeinformations were filled in a Performa and informations were taken from case records. Results: This audit report included 200 women. 23.3%patients of vaginal hysterectomy were in the age group of 40-45 years while 35.7%patients of abdominal hysterectomy were in the age of 51-55years. Main indication for abdominal hysterectomy (85.5%) was fibroid uterus while for vaginal hysterectomy (66.6%) was Uterovaginal prolapse.Most common immediate post operative complication in abdominal and vaginal hysterectomy was fever in 42.8% and 20.0% respectively.Intraoperative visceral injuries were done in 4 patients in abdominal hysterectomy while no injury was done in vaginal hysterectomy. 44(80%)patients of vaginal hysterectomy were discharged with in 7 days of hospitalization while 64 (44%) patients of abdominal hysterectomy weredischarged with in 7 days of hospitalization. Conclusion: Hysterectomy either abdominal or vaginal is very safe and there were no lethalcomplication except few minor complications and also there was no mortality.

scholarly journals Clinico-Hematological and cytogenetic spectrum of adult myelodysplastic syndrome The first retrospective cross-sectional study in Iranian patients

2021 ◽  
Author(s):  
Mostafa Paridar ◽  
Kazem Zibara ◽  
Seyed Esmaeil Ahmadi ◽  
Abbas Khosravi ◽  
Maral Soleymani ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Cross Sectional Study ◽  
Cytogenetic Abnormality ◽  
Sectional Study ◽  
Trisomy 8 ◽  
Cross Sectional ◽  
Iron Storage ◽  
Monosomy 7 ◽  
Female Ratio ◽  
Cytogenetic Abnormalities

Abstract Background Myelodysplastic syndrome (MDS), a heterogeneous group of hematopoietic malignancy, has been shown to present different cytogenetic abnormalities, risk factors, and clinico-hematological features in different populations and geographic areas. Herein, we determined the cytogenetic spectrum and clinico-hematological features of Iranian MDS patients for the first time. Methods This prospective cross-sectional study was conducted on 103 patients with MDS in Ahvaz, southwest of Iran, from 2014 to 2018. Clinical presentations, complete blood counts (CBC), and bone marrow (BM) biopsy samples were assessed. Perls' staining was used to evaluate BM iron storage. The cytogenetic evaluation was performed using the conventional G banding method on the BM. Results Patients’ median age was 62.3 (ranged from 50–76), and the majority were male (72.8%). The most common clinical symptom at the time of admission was fatigue (n = 33) followed by pallor (n = 27). The most common subgroup was MDS-Multi Lineage Dysplasia (MDS-MLD) (n = 38, 36.8%), followed by MDS-Single Lineage Dysplasia (MDS-SLD) (n = 28, 18.4%). A normal karyotype was observed in 59 patients (57.3%), while 44 patients (42.7%) had cytogenetic abnormalities. Trisomy 8 (+ 8) was the most common cytogenetic abnormality (n = 14) followed by dell 17p (n = 9) and monosomy 7 (-7) (n = 7). Twelve patients (11.65 %) were transformed to AML. Conclusion Our data betokened that among our MDS patients, Trisomy 8 is the predominant cytogenetic abnormality, and MDS-MLD and MDS-SLD are the most common of subtypes. Noteworthy, the male: female ratio was slightly higher in Iran than in previous reports from other parts of the world. Our study is the first report of the clinical, hematological, and cytogenetic spectrum of MDS patients in Iran

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