A Review on Coronaviruses: The Infectious Agent to Animals and Human

2020 ◽  
Vol 30 (1) ◽  
pp. 1 ◽  
Author(s):  
NiLuh Putu Indi Dharmayanti ◽  
Diana Nurjanah
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Infectious Diseases ◽  
Digestive Tract ◽  
Rna Virus ◽  
Scientific Information ◽  
Infectious Agent ◽  
Structural Proteins ◽  
Fish Market ◽  
The World

Coronavirus is a non-segmented, positive-stranded RNA virus with four main structural proteins, namely Spike (S), Membrane (M), Envelope (E), and Nucleocapsid (N) proteins. Coronavirus can cause diseases in the respiratory and digestive tract, as well as in central nervous system of animals and humans. There are four genera in the Orthocoronavirinae subfamily, including <em>Alphacoronavirus</em>, <em>Betacoronavirus, Gammacoronavirus</em>, and <em>Deltacoronavirus</em>. <em>Alphacoronavirus </em>and <em>Betacoronavirus </em>are commonly found in mammals, while <em>Gammacoronavirus </em>and <em>Deltacoronavirus </em>are found to infect  birds and mammals. Until 2018, zoonoses coronaviruses consisted of SARS-CoV and MERS-CoV. Coronavirus became worldwide concern after it was identified as the cause of the pneumonia outbreak occurred at the end of 2019 in China. The coronavirus is associated with the fish market in Wuhan, then the disease is called COVID-19 (Coronavirus Infectious Diseases-19) caused by SARS-CoV-2. Virus SARS-CoV-2 has infected &gt;1.6 million people around the world and until the end of March 2020, it caused more than 99.000 deaths including 3.512 cases with the total number of deaths to 306 in Indonesia. This paper discusses Coronavirus and scientific information related to Coronaviruses in which several variants are zoonoses.

scholarly journals COVID-19 Vaccination: From Interesting Agent to the Patient

Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 120
Author(s):  
Anis Daou
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Gastrointestinal Tract ◽  
Circulatory System ◽  
The Novel ◽  
Lead Compound ◽  
Fda Approval ◽  
The World ◽  
The Central Nervous System ◽  
Novel Coronavirus

The vaccination for the novel Coronavirus (COVID-19) is undergoing its final stages of analysis and testing. It is an impressive feat under the circumstances that we are on the verge of a potential breakthrough vaccination. This will help reduce the stress for millions of people around the globe, helping to restore worldwide normalcy. In this review, the analysis looks into how the new branch of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) came into the forefront of the world like a pandemic. This review will break down the details of what COVID-19 is, the viral family it belongs to and its background of how this family of viruses alters bodily functions by attacking vital human respiratory organs, the circulatory system, the central nervous system and the gastrointestinal tract. This review also looks at the process a new drug analogue undergoes, from (i) being a promising lead compound to (ii) being released into the market, from the drug development and discovery stage right through to FDA approval and aftermarket research. This review also addresses viable reasoning as to why the SARS-CoV-2 vaccine may have taken much less time than normal in order for it to be released for use.

scholarly journals An overview of travel-associated central nervous system infectious diseases: risk assessment, general considerations and future directions

2014 ◽  
Vol 4 (8) ◽  
pp. 589-596
Author(s):  
Morteza Izadi ◽  
Arman Is'haqi ◽  
Mohammad Ali Is'haqi ◽  
Nematollah Jonaidi Jafari ◽  
Fatemeh Rahamaty ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Central Nervous System ◽  
Nervous System ◽  
Infectious Diseases ◽  
Future Directions

scholarly journals Suppurative infectious diseases of the central nervous system in domestic ruminants

2017 ◽  
Vol 37 (8) ◽  
pp. 820-828 ◽  
Author(s):  
Guilherme Konradt ◽  
Daniele M. Bassuino ◽  
Klaus S. Prates ◽  
Matheus V. Bianchi ◽  
Gustavo G.M. Snel ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Infectious Diseases ◽  
Neurological Disease ◽  
Etiologic Agent ◽  
Domestic Ruminants ◽  
The Central Nervous System ◽  
Positive Immunostaining

ABSTRACT: This study describes suppurative infectious diseases of the central nervous system (CNS) in domestic ruminants of southern Brazil. Reports from 3.274 cattle, 596 sheep and 391 goats were reviewed, of which 219 cattle, 21 sheep and 7 goats were diagnosed with central nervous system inflammatory diseases. Suppurative infectious diseases of the CNS corresponded to 54 cases (28 cattle, 19 sheep and 7 goats). The conditions observed consisted of listerial meningoencephalitis (8 sheep, 5 goats and 4 cattle), suppurative leptomeningitis and meningoencephalitis (14 cattle, 2 goats and 1 sheep), cerebral (6 cattle and 2 sheep), and spinal cord (7 sheep) abscesses, and basilar empyema (4 cattle and 1 sheep). Bacterial culture identified Listeria monocytogenes (9/54 cases), Escherichia coli (7/54 cases), Trueperella pyogenes (6/54 cases) and Proteus mirabilis (1/54 cases). All cases diagnosed as listeriosis through histopathology yielded positive immunostaining on immunohistochemistry, while 12/17 of the cases of suppurative leptomeningitis and meningoencephalitis presented positive immunostaining for Escherichia coli. Meningoencephalitis by L. monocytogenes was the main neurological disease in sheep and goats, followed by spinal cord abscesses in sheep. In cattle, leptomeningitis and suppurative meningoencephalitis was the most frequent neurological disease for the species, and E. coli was the main cause of these lesions. Basilar empyema, mainly diagnosed in cattle, is related to traumatic injuries, mainly in the nasal cavity, and the main etiologic agent was T. pyogenes.

Occurrence of members of the insulin superfamily in central nervous system and digestive tract of protochordates

1993 ◽  
Vol 99 (4) ◽  
pp. 277-285 ◽  
Author(s):  
M. Reinecke ◽  
D. Betzler ◽  
K. Drakenberg ◽  
S. Falkmer ◽  
V. R. Sara
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Digestive Tract ◽  
Insulin Superfamily

scholarly journals Historical aspects of studying the influence of physical activity on the mental health of people

2021 ◽  
Vol 8 (1) ◽  
pp. 39-48
Author(s):  
Sergii Ivashchenko
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Higher Education ◽  
Central Nervous System ◽  
Nervous System ◽  
Physiological State ◽  
Scientific Information ◽  
Teaching Staff ◽  
Historical Process ◽  
Joint Activities

This article presents the main results of work on the study of the issue of the historical process of improving knowledge about the influence of physical activity of a person on the level of his mental health. Based on the results of the analysis of scientific information presented in modern domestic and foreign literary sources, the conclusion was substantiated that the historical process of improving knowledge about human nature and his mental activity in recent years has reached the highest level of development. The study of the long-term experience of scientists in many countries of the world gives grounds to assert that the beginning of the process of targeted study of the effect of physical activity on human mental functions was laid back in the last century. However, scientists have achieved the most outstanding results in this area of scientific research in recent decades. The historical need for in-depth research in this scientific direction was maturing gradually and was due to the peculiarities of the course of scientific and technological progress in general. Due to the fact that it was in recent decades that many discoveries were made, which formed the basis of modern methods for studying the physiological state of a person and his intellectual functions, there was obvious progress in the study of the mental health of persons whose central nervous system works under conditions of extreme intellectual and psycho-emotional stress. Scientists working in the field of physical education and sports, in collaboration with scientists in the field of education and health, have significantly intensified their joint activities and developed modern complexes of measures aimed at studying the mental health of students and representatives of the teaching staff of state institutions of higher education. This contingent of the subjects was not chosen by chance. The fact is that the learning process in higher education institutions is associated with intense loads on the central nervous system of both students and teachers, as well as on some of their senses (in particular, on the visual and auditory analyzers).

Acute Pancreatitis Following Organophosphate Compound Poisoning: A Case Report

2021 ◽  
Vol 1 (4) ◽  
pp. 250-252
Author(s):  
Suman K. Jha ◽  
Sabin Chaulagain ◽  
Shiva Kumar Ojha ◽  
Angela Basnet Neela Sunuwar ◽  
Akanchha Khadka
Keyword(s):  
Central Nervous System ◽  
Acute Pancreatitis ◽  
Nervous System ◽  
Case Report ◽  
Rural Communities ◽  
South Asian ◽  
Asian Countries ◽  
Organophosphate Compounds ◽  
The World ◽  
Agrarian Communities

Organophosphate compounds are chemicals containing central phosphate molecules with alkyl or aromatic substituent’s. They occur in diverse forms and are used as pesticides, herbicides, nerve agents, etc. Organophosphate compounds are frequently used as pesticides in agrarian communities all across the world. South Asian countries such as Nepal use vast quantities of Organophosphate compounds for pest control in agriculture. Therefore, accidental and suicidal ingestion of Organophosphate compound poisoning has been common especially among the agricultural rural communities. Apart from muscarinic, nicotinic and central nervous system effects in rare instances, Organophosphate compounds are known to cause pancreatitis.

Immune and Infectious Diseases

2018 ◽  
pp. 430-470
Author(s):  
Andrea C. Adams
Keyword(s):  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Young People ◽  
Connective Tissue ◽  
Infectious Diseases ◽  
Temporal Profile ◽  
Immune Mediated ◽  
The Central Nervous System ◽  
The Common

Many immune-mediated diseases and infections affect the central and peripheral nervous systems. The common feature that characterizes both immune-mediated diseases and infections is a subacute temporal profile. Immune-mediated disease can affect only the nervous system or involve the nervous system as part of a systemic illness, as in vasculitis and connective tissue disease. Multiple sclerosis (MS), the most common disabling neurologic illness of young people, is the prototypical immune-mediated disease of the central nervous system (CNS).

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