scholarly journals The importance of melatonin in the regulation of metabolism, eating behavior, sleep, and the prospects for the use of melatonin drugs for obesity treatment

2021 ◽  
Vol 18 (2) ◽  
pp. 112-124
Author(s):  
E. S. Tsvetkova ◽  
T. I. Romantsova ◽  
M. G. Poluektov ◽  
G. E. Runova ◽  
I. V. Glinkina ◽  
...  

Melatonin is a special hormone that act as an internal synchronizer of circadian rhythms, the organism physiology and behavior to the environmental day and night and seasons of the year. The present urban society and the industrial production processes as organized should be considered, as both depend on the presence of indoor lights during the night and include the profuse use of electronic devices whose screens are rich in blue wavelength light. Light during the night delays the beginning of the secretory episode of melatonin and blunts its peak, causing chronic hypomelatoninemia. Hypomelatonemia, that causes deprivation of sleep and eating behavior disorders, along with low physical activity, can be the reason of the obesity, «non-infectious epidemic of the 21st century». According to this, the use of melatonin drugs for obesity treatment can be effective. Further prospective, controlled, randomized trials in this area are required to confirm this hypothesis.

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246172
Author(s):  
Karan Srisurapanont ◽  
Yanisa Samakarn ◽  
Boonyasit Kamklong ◽  
Phichayakan Siratrairat ◽  
Arina Bumiputra ◽  
...  

Objective This review aimed to determine the efficacy of blue-wavelength light therapy (BWLT) for post-traumatic brain injury (TBI) sleepiness, sleep disturbance, depression, and fatigue. Methods Pubmed, Scopus, Web of Science, Cochrane Library, Academic Search Complete, and CINAHL. Included trials were randomized controlled trials (RCTs) of BWLT in adults with a history of TBI. Outcomes of interest included sleepiness, sleep disturbance, depression, or fatigue. Two reviewers independently screened the searched items, selected the trials, extracted the data, and rating the quality of trials. We aggregated the data using a random-effect, frequentist network meta-analysis (NMA). Results We searched the databases on July 4, 2020. This review included four RCTs of 117 patients with a history of TBI who were randomized to received BWLT, amber light therapy (ALT), or no light therapy (NLT). Moderate-quality evidence revealed that: i) BWLT was significantly superior to NLT in reducing depression (SMD = 0.81, 95% CI = 0.20 to 1.43) ii) BWLT reduced fatigue at a significantly greater extent than NLT (SMD = 1.09, 95% CI = 0.41 to 1.76) and ALT (SMD = 1.00, 95% CI = 0.14 to 1.86). Low-quality evidence suggested that BWLT reduced depression at a greater extent than ALT (SMD = 0.57, 95% CI = 0.04 to 1.10). Low-quality evidence found that the dropout rates of those receiving BWLT and ALT were not significantly different (RR = 3.72, 95% CI = 0.65 to 21.34). Conclusion Moderate-quality evidence suggests that BWLT may be useful for post-TBI depression and fatigue.


2019 ◽  
Vol 60 (2) ◽  
pp. 66-70
Author(s):  
Natalya V. Dolotova ◽  
O. M. Filkina ◽  
A. I. Malyshkina ◽  
I. L. Kudryashova

The article presents data concerning prevalence and structure of disability in children aged 0-4 years being brought up in specialized child homes of Ivanovo in 2006-2012. During this period decreasing ofrate ofdisability up to 1.8 times was established. In the structure of diseases conditioned development of disability in children, increasing of percentage of inherent malformations, psychic disorders and behavior disorders was marked. The increasing of number of children with limitation of capacity of independent movement and self-service was established. The number of children with mental disorders, visceral and metabolic disorders and nutrition disorders, psychic and statodynamic disorders increased. The revealed characteristics of disability in child’s home permit to properly establish process of complex rehabilitation with emphasis on the most frequent disorders.


Author(s):  
Tanusree Chakraborty ◽  
Raiswa Saha

Advergames are a very dynamic marketing tool for companies coupled with being interactive, fulfilled, networked, creating positive connection with consumers, provides pleasurable environment marked by two-way communication. Food advergames target children population who without knowing the persuasive content of the games engage in the play. The purpose of this chapter is to highlight the psychodynamics of food advergames, how advergames influences children's eating attitude and behavior, and also discusses about the health hazards that food advergames bring in with itself. Finally, the chapter throws light on the impact and concerns of food advergames on children's eating behavior.


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