scholarly journals Capacities of complex ultrasonography in the differential diagnosis and management of thyroid nodular masses

2009 ◽  
Vol 55 (4) ◽  
pp. 49-54 ◽  
Author(s):  
A E Ul'yanova ◽  
L L Yarchenkova

The review presents the capacities of Doppler ultrasound study in the differential diagnosis and management of thyroid nodular masses. The problem of goiter does not presently lose its urgency. Palpable thyroid nodular masses are detectable in 4-7% of the worlds population [3, 4, 25] and the detection rate of thyroid abnormalities via radiation studies is 20 to 50% [4, 5]. Complex ultrasonography (USG) increases the obtained volume of information and its clinical value in nodular goiter. Examination of blood circulation in the thyroid and nodular masses involves two-dimensional gray-scale echography, color Doppler coding and Doppler spectrum analysis. The present Doppler study with color Doppler coding makes it possible to unify an assessment of the distribution of color flow maps in the vessels of nodular masses. Doppler spectrum analysis in nodular masses can confirm the enhanced blood flow in nodular tissue as compared with that in the intact parenchyma (increased linear blood flow velocities in the intranodular and/or perinodular arteries as compared with those in the adjacent tissue arteries). Doppler USG introduced early after thyroid surgery provides objective information on the area operated on and evaluates the course of its wound process, diagnoses early postoperative complications, and defines the adequacy of performed surgical intervention [1, 3, 7].

2017 ◽  
Vol 6 (1) ◽  
pp. 27-30
Author(s):  
Farhana Shimu ◽  
Enayet Karim ◽  
Abul Hashem Khan ◽  
Akhter Ahmed ◽  
Sultana Parvin ◽  
...  

Background: Write the background in 1 to 2 sentences.Objective: The purpose of the present study was to estimate the efficacy of resistive index (RI) of color Doppler ultrasonography in different space occupying liver lesions.Methodology: This cross sectional study was conducted at in Bangabandhu Sheik Mujib Medical University (BSMMU), Dhaka from July 2010 to December 2012. All the patients presented with the suspicion of hepatic space occupying lesions were enrolled for this study who were later diagnosed clinically or ultrasonographically. This patients were also examined by color Doppler flow imaging. All patients were examined by gray scale ltrasonography, color Doppler and FNAC. To visualize the blood flow, standard color Doppler sonography is used for each lesion. Within the lesions, pulsed Doppler samples are assessed whenever possible on the basis of pulsatile flow. At least three measurements of resistive index (RI) of intra tumoral and peritumoral arterial blood flow would be the last mean value.Results: The detection rate of arterial flow in primary malignant tumors was 94.4% and 87.7% in hepatic metastasis. Doppler spectrum analysis showed the resistance index in primary malignant tumor was 0.75±0.12, 0.73±0.09 in metastatic tumor and was below 0.6 in benign lesions. The difference was significant (p<0.001). This difference was related with its histopathologic structure. The arterial flow with RI >0.6 in CDFI within the liver lesion can be regarded as a criterion of malignant tumors, RI <0.6 can be regarded as benign lesions.Conclusion: RI is more helpful in differential diagnosis of benign and malignant lever lesions.J Shaheed Suhrawardy Med Coll, June 2014, Vol.6(1); 27-30


2021 ◽  
Vol 11 (6) ◽  
pp. 1608-1615
Author(s):  
Ding Zuopeng ◽  
Liu Weiyong ◽  
Hu Chunmei ◽  
Wang Tao ◽  
Wang Mingming

The incidence of breast cancer ranks first among female malignant tumor. With the increase of the sensitivity of color Doppler ultrasound blood flow, the blood flow distribution in and around the tumor can be clearly displayed, and the analysis of hemodynamic parameters is provided, which provides convenience for the study of tumor blood flow characteristics. Studies have shown that tumor cells can secrete a substance called angiogenesis factor, which makes the tumor site form a rich vascular network to promote tumor growth and metastasis. The tumor has many new blood vessels, abnormal structure, thin wall, lack of muscle layer, and is prone to form arteriovenous rash. These characteristics provide a pathological basis for color Doppler flow imaging (CDFI) for the diagnosis of breast cancer. This article discusses the role of two-dimensional sonographic features in the differential diagnosis of benign and malignant breast masses, CDFI was used to study the blood flow distribution and hemodynamic characteristics in benign and malignant breast masses; explore the value of blood flow characteristics and blood flow parameters in the differential diagnosis of breast masses. The experimental results show that the detection rate of blood flow signals and the classification of blood flow signals in the malignant group are higher than those in the benign group, mainly level II and III blood flow, and the irregular branched blood flow is more common, especially when the tumor appears penetrating blood flow supports the diagnosis of malignancy. PSV, RI and PI have a certain differential meaning in the diagnosis of benign and malignant breast masses. PSV, RI and PI of malignant masses are higher than benign masses. For tumors without obvious necrosis, the larger the tumor diameter, the richer the blood flow and the higher the blood flow grade is. The malignant tumors have more blood flow than the benign ones.


2007 ◽  
Vol 48 (6) ◽  
pp. 628-634 ◽  
Author(s):  
M. Loy ◽  
E. Perra ◽  
A. Melis ◽  
M. E. Cianchetti ◽  
M. Piga ◽  
...  

Background: Amiodarone-induced thyrotoxicosis (AIT) may be caused by excessive thyroidal hormone synthesis and release (type 1) or by a destructive process (type 2). This differentiation is considered essential for therapeutic choice. Purpose: To evaluate the utility of color-flow Doppler sonography (CFDS) in the differential diagnosis and management of AIT. Material and Methods: The clinical and laboratory data, thyroid sonography (grayscale sonography [GSS], CFDS), thyroid radioiodine uptake (RAIU) and thyroid scintigraphy, treatment, and clinical outcome were retrospectively reviewed in 21 AIT patients. The CFDS pattern of thyroid nodules was separately described from that of the perinodular parenchyma, and AIT was classified as type 1 (increased blood flow) or type 2 (low/no blood flow). Type 1 AIT patients were treated with methimazole (alone or associated with potassium perchlorate), while type 2 patients were treated with prednisone or amiodarone withdrawal alone. Results: Eleven patients with increased blood flow were considered as type 1, and 10 with low/no blood flow as type 2. Ten of the 11 patients in the first group showed a hypervascular nodular pattern, while one showed a hypervascular parenchymal pattern. Clinical diagnoses were toxic nodular goiter and Graves' disease, respectively. Of the 10 patients with low/no blood flow, six had normal thyroid volume, three small diffuse goiter, and one small multinodular goiter. The clinical outcome showed that 20 of the 21 patients were treatment responsive. Conclusion: CFDS is a useful tool in the differential diagnosis of AIT. This differentiation appeared to be of clinical relevance as regards therapeutic choice. Separate evaluation of parenchymal blood flow from that of nodules may prove beneficial in the diagnosis of underlying thyroid diseases in patients with type 1 AIT.


2008 ◽  
Vol 20 (1) ◽  
pp. 236
Author(s):  
A. Hanstedt ◽  
K. Höffmann ◽  
Ä. Honnens ◽  
H. Bollwein ◽  
C. Wrenzycki

The population of cumulus–oocyte complexes (COCs) used in OPU–IVP (ovum pick-up combined with in vitro production of embryos) is largely homogeneous due to repeated sessions resulting in the elimination of dominant and atretic follicles, especially when a 3–4 day interval is used. However, on average only 20% of the COCs develop to the blastocyst stage (Merton et al. 2003 Theriogenology 59, 651–674). Different blood flow changes within the follicle wall influence the fate of the follicles, and detectable blood flow and vasculature are associated with follicle viability. Furthermore, blood flow in follicles may be involved in not only selection of the dominant follicle but also early follicular development including follicular recruitment (Miyamoto et al. 2006 J. Reprod. Dev. 52, 153–160). However, no data are available regarding the quality of the COCs collected from follicles with or without blood flow. The purpose of this study was to determine whether qualitative perifollicular blood flow changes can be used to predict the developmental competence of COCs collected during repeated OPU sessions. Lactating Holstein cows were used as oocyte donors. After dominant follicle removal, OPU was performed twice weekly employing a 7.5-MHz transducer (GE 8C-RS) of an ultrasound scanner (GE Logiq Book). Follicle size and Doppler characteristics (color flow imaging) were recorded by transvaginal ultrasonography just before COC collection. Due to technical limitations for measurement of blood flow in small individual follicles, only the presence or absence of blood flow was assessed for each follicle. When a clearly visible blue or red spot (blood flow) was detected in the follicle wall, it was considered as a follicle with detectable blood flow. Follicles with or without detectable blood flow from each individual cow were aspirated separately. After morphological classification of COCs, standard protocols for IVP were used for embryo production. Cleavage and blastocyst rates were recorded at Day 3 and Day 8, respectively. In total, 464 (246 with and 218 without detectable blood flow) follicles e3 mm were aspirated. The percentage of follicles with detectable blood flow increased depending on follicle size (3 mm: 28.7, 4 mm: 48.4, 5 mm: 50.5, 6 mm: 62.5, 7 mm: 64.8, 8 mm: 71.4, and 9 mm: 76.9). Cleavage rates for COCs stemming from follicles with or without detectable blood flow did not show differences, 45.5% (35/77) and 56.7% (38/67), respectively. The rates of blastocyst formation were also similar in COCs originating from follicles with and without detectable blood flow, 16.9% (13/77) and 14.9% (10/67), respectively. These results show that perifollicular blood flow increases during early follicular growth. Within the detection limits of this study, differences in perifollicular blood flow during repeated OPU sessions twice weekly did not seem to be predictive of oocyte competence. We acknowledge the Ruthe Research Farm, Germany, for providing the animals, and Masterrind GmbH, Germany, for donating the semen.


1999 ◽  
Vol 22 (2) ◽  
pp. 87-96 ◽  
Author(s):  
Emely Z. Karam ◽  
Luis Destarac ◽  
Thomas R. Hedges ◽  
Paula A. Heggerick

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Léo Puyo ◽  
Michel Paques ◽  
Michael Atlan

AbstractLaser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we present a digital method based on the Doppler spectrum asymmetry that reveals the local direction of blood flow with respect to the optical axis in out-of-plane vessels. This directional information is overlaid on standard grayscale blood flow images to depict flow moving towards the camera in red and flow moving away from the camera in blue, as in ultrasound color Doppler imaging. We show that thanks to the strong contribution of backscattering to the Doppler spectrum in out-of-plane vessels, the local axial direction of blood flow can be revealed with a high temporal resolution, which enables us to evidence pathological blood flow reversals. We also demonstrate the use of optical Doppler spectrograms to quantitatively monitor retinal blood flow reversals.


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