scholarly journals Hiperplasia Fibrosa Inflamatoria: Reporte de un caso

2021 ◽  
Vol 13 (1) ◽  
pp. 136-140
Author(s):  
Brian Andrés García Orellana ◽  
María de Lourdes León Vintimilla ◽  
Martha Alejandra Cornejo Córdova
Keyword(s):  
Older Adults ◽  
Oral Mucosa ◽  
Histopathological Examination ◽  
Case Reports ◽  
Conventional Technique ◽  
Oral Lesions ◽  
Removable Dental Prosthesis ◽  
Removable Prosthesis ◽  
The Right

BACKGROUND: Inflammatory fibrous hyperplasia associated with the use of removable dental prosthesis (IFH) is an adaptive lesion caused by long-term trauma exerted by a poorly adapted removable prosthesis on the oral mucosa, usually in the vestibular sulcus. Its diagnosis and treatment is imperative, due to its potential to cause discomfort to the patient, altering aesthetics, phonectics and chewing. CASE REPORTS: A 41-year-old denture wearer woman was referred due to discomfort in the right lower vestibular sulcus, the clinical examination showed a bilobed enlargement with an invagination where the edge of the prosthesis fits, the patient has worn the prosthesis for 15 years. EVOLUTION: Resection with scalpel (conventional technique) was performed. The histopathological examination reported inflammatory fibrous hyperplasia and a new total removable bimaxillary prosthesis was made for the patient. CONCLUSIONS: HFI is one of the main oral lesions in older adults denture wearers and it causes aesthetic and functional alterations; it is produced by the constant irritation caused by the settlement of the prosthesis borders on the mucovestibular sulcus as a consequence of alveolar resorption. Treatment is meant to eliminate the injury and its etiology; the absence of lesions on the mucosa and the bottom of the sulcus is completely necessary.

scholarly journals Alternative Leprosy Treatment Using Rifampicin Ofloxacin Minocycline (ROM) Regimen – Two Case Reports

2019 ◽  
Vol 11 (3) ◽  
pp. 89-93
Author(s):  
Yohanes Widjaja ◽  
Khairuddin Djawad ◽  
Saffruddin Amin ◽  
Widyawati Djamaluddin ◽  
Dirmawati Kadir ◽  
...  
Keyword(s):  
Clinical Improvement ◽  
Alternative Treatment ◽  
Histopathological Examination ◽  
Case Reports ◽  
Erythematous Plaque ◽  
First Case ◽  
Satisfactory Outcome ◽  
Significant Clinical Improvement ◽  
The Right

Abstract Introduction. Leprosy is a disease that predominantly affects the skin and peripheral nerves, resulting in neuropathy and associated long-term consequences, including deformities and disabilities. According to the WHO classification, there are two categories of leprosy, paucibacillary (PB) and multibacillary (MB). The standard treatment for leprosy employs the use of WHO MDT (Multi Drug Treatment) regimen, despite its multiple downsides such as clofazimine-induced pigmentation, dapsone-induced haematological adverse effects, poor compliance due to long therapy duration, drug resistance, and relapse. Multiple studies and case reports using ROM regimen have reported satisfactory results. Nevertheless, there are still insufficient data to elucidate the optimum dosage and duration of ROM regimen as an alternative treatment for leprosy. Previous experience from our institution revealed that ROM regimen given three times weekly resulted in a satisfactory outcome. Case Reports. We report two cases of leprosy treated with ROM regimen from our institution. The first case was PB leprosy in a 64-year-old male who presented with a single scaly plaque with erythematous edge on the right popliteal fossa. Sensibility examination showed hypoesthesia with no peripheral nerve enlargement. Histopathological examination confirmed Borderline Tuberculoid leprosy. ROM regimen was started three times weekly for 6 weeks and the patient showed significant clinical improvement at the end of the treatment with no reaction or relapse until after 6 months after treatment. The second case was MB leprosy in a 24-year-old male patient with clawed hand on the 3rd-5th phalanges of the right hand and a hypoesthetic erythematous plaque on the forehead. Histopathology examination confirmed Borderline leprosy. The patients received ROM therapy 3 times a week with significant clinical improvement after 12 weeks. Conclusion. ROM regimen given three times weekly for 6 weeks in PB leprosy and 12 weeks in MB leprosy resulted in a significant clinical improvement. Thus, ROM regimen could be a more effective, safer, faster alternative treatment for leprosy.

scholarly journals Atypical Insufficiency Fractures Associated with Long-Term Bisphosphonate Therapy: 3 Case Reports

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Sandrine Malochet Guinamand
Keyword(s):  
Case Reports ◽  
Femoral Fractures ◽  
Bisphosphonate Therapy ◽  
Fracture Site ◽  
Atypical Fracture ◽  
Mineral Research ◽  
The Third ◽  
First Case ◽  
The Right

Atypical femoral fractures as defined by the American Society for Bone and Mineral Research (ASBMR) are linked with long-term bisphosphonate therapy. We report the cases of 3 patients treated with bisphosphonates, and presenting non femoral atypical fracture. Our first patient presented with a series of fractures after being treated with risedronate: the left tibia, bilateral tibial plateau successively, the left femoral and tibial metaphysis, the right tibia and calcaneus, the left talus, and the left talar dome. The second patient had been taking alendronate and presented with a spontaneous fracture of the spine of the left scapula. The third patient had been treated with alendronate and presented with a fracture of the upper right tibial diaphysis with an unusual oblique orientation. These fractures could be suggestive of bisphosphonate therapy failure or stress fractures. However, the number of fractures in our first case, the fracture site in the second and the fracture line orientation in the third brings to mind the hypothesis of atypical non femoral fractures associated with bisphosphonate therapy. We therefore suggest the possibility of a new type of atypical fracture in patients treated with bisphosphonates, and whose causal relationship with bisphosphonates is even more difficult to demonstrate.

scholarly journals Diagnostic Mystery — a Rare Right Ventricular Cardiac Hemangioma: a Case Report

2021 ◽  
Author(s):  
Jingya Fan ◽  
Lei Guo ◽  
Peng Teng ◽  
Xiaoyi Dai ◽  
Qi Zheng ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Histopathological Examination ◽  
Surgical Removal ◽  
Cardiac Tumors ◽  
Term Survival ◽  
Cardiac Hemangioma ◽  
First Choice ◽  
The Right ◽  
Choice Of Therapy

Abstract Background: Cardiac hemangiomas are rare in all kinds of benign cardiac tumors. Although cardiac hemangiomas affect all ages and may occur anywhere within the heart, right ventricular hemangiomas are extremely uncommon.Case presentation: We report a 56-year-old woman presented with chest tightness and breath shortness for 3 months. Transthoracic echocardiography and coronary computed tomography angiography showed a mass located adjacent to the apex of the right ventricle but both failed to figure out where the mass originated from, remaining a diagnostic mystery preoperatively. The mass was removed successfully and the histopathological examination confirmed it was hemangioma.Conclusions: Cardiac magnetic resonance should be the ultimate diagnostic tool of cardiac tumors. Surgical removal, associated with a low recurrence rate and long-term survival benefits, should be the first choice of therapy for cardiac hemangiomas.

scholarly journals Acute haemoperitoneum caused by endometriosis infiltrating the uterine artery - Two case reports and a literature review

2021 ◽  
Vol 13 (3) ◽  
pp. 265-270
Author(s):  
A.-S. Vandenameele ◽  
L Platteeuw ◽  
H Alaerts
Keyword(s):  
Literature Review ◽  
Uterine Artery ◽  
Histopathological Examination ◽  
Case Reports ◽  
Free Fluid ◽  
Bipolar Coagulation ◽  
Lower Quadrant ◽  
Arterial Bleeding ◽  
The Right ◽  
Infiltrating Endometriosis

Objective: We report 2 cases of haemoperitoneum due to a bleeding of the uterine artery caused by infiltrating endometriosis. We have also conducted a literature review on endometriosis-related intra-abdominal haemorrhage and wrote a practical guideline on how this entity can be recognized and handled. Patients: Case 1: A 49-year-old multiparous woman presented with intense stabbing pain in the lower abdomen during her menstruation. CT angiography showed a bleeding from a side branch of the internal iliac artery. Laparoscopy was performed and an active bleeding from the right uterine artery was confirmed, clearly caused by infiltrating endometriosis lesions. Haemostasis was achieved by bipolar coagulation. Case 2: A 29-year-old nulliparous woman was admitted for observation because of heavy stabbing pain in the right lower quadrant and presence of free fluid on CT abdomen. The day after the admission, laparoscopy was performed because of a decreasing haemoglobin level. An arterial bleeding from the right parametrium was observed, probably originating from the right uterine artery. Histopathological examination of a biopsy of the right parametrium proved the presence of endometriosis. Haemostasis was achieved by bipolar coagulation. Conclusion: Although endometriosis-related haemoperitoneum is a rare entity, this diagnosis should be considered when a patient presents with an intra-abdominal haemorrhage during menstruation or withdrawal bleeding - especially in case of a history or suspicion of endometriosis. Laparoscopy is the cornerstone of the treatment.

Ectopic Recurrence of Craniopharyngioma after an Interhemispheric Transcallosal Approach: Case Report

Neurosurgery ◽  
2002 ◽  
Vol 50 (3) ◽  
pp. 639-645 ◽  
Author(s):  
Jeannette M. Liu ◽  
Ira M. Garonzik ◽  
Charles G. Eberhart ◽  
Prakash Sampath ◽  
Henry Brem
Keyword(s):  
Vasogenic Edema ◽  
Case Reports ◽  
Postoperative Radiotherapy ◽  
Transcallosal Approach ◽  
Ectopic Recurrence ◽  
Microsurgical Resection ◽  
Surgical Field ◽  
The Right

Abstract OBJECTIVE AND IMPORTANCE: Ectopic recurrence of a craniopharyngioma is a rare postoperative complication. We present a case of a craniopharyngioma that ectopically recurred along the tract of a previous surgical route. CLINICAL PRESENTATION: A 73-year-old female patient presented 8 years earlier with a suprasellar craniopharyngioma. She underwent a right frontal craniotomy, with an interhemispheric transcallosal approach, for total microsurgical resection of the tumor. No postoperative radiotherapy was administered. Four years after surgery, magnetic resonance imaging studies revealed a well-circumscribed, heterogeneously enhancing, parasagittal mass with significant vasogenic edema in the right frontal lobe. Enlargement of the lesion was noted in subsequent radiological evaluations until 8 years after surgery, when the patient experienced a significant decline in neurocognitive status and the mass was surgically resected. INTERVENTION: Gross total resection of a histologically confirmed craniopharyngioma was achieved. CONCLUSION: To our knowledge, only eight previous case reports described the ectopic recurrence of a craniopharyngioma. Transplantation of tumor cells along the tract of a previous surgical route in six cases and dissemination in cerebrospinal fluid in two cases are presumed to be the primary mechanisms by which these ectopic recurrences occurred. The results of our literature review led us to conclude that total surgical resection, combined with careful inspection and irrigation of the surgical field, is the optimal treatment for preventing ectopic recurrences. Furthermore, it is recommended that, after primary craniopharyngioma resection, patients undergo long-term clinical and radiological follow-up monitoring for the rare development of an ectopically recurring tumor.

scholarly journals Differential diagnoses of pseudolymphomatous folliculitis: considerations as regards one case

2021 ◽  
Vol 14 (4) ◽  
pp. e238291
Author(s):  
José Bruno Mendoza Ramírez ◽  
Dafne Ayala ◽  
Adrian Heald ◽  
Gabriela Y C Moreno
Keyword(s):  
Basement Membrane ◽  
Clinical Case ◽  
Histopathological Examination ◽  
Case Reports ◽  
Lymphoid Hyperplasia ◽  
Hair Follicles ◽  
Clinical Suspicion ◽  
Sweat Glands ◽  
The Right ◽  
Immunohistochemical Studies

Pseudolymphomatous folliculitis (PLF) is a rare disease of cutaneous lymphoid hyperplasia, with a low index of clinical suspicion. We present the clinical case of a 19-year-old male patient, with a solitary violet erythematous nodule of 6 months of evolution, located in the right infraorbital region, without presenting another symptomatology. Histopathological examination showed a lymphocytic infiltrate that surrounds the hair follicles, sebaceous and sweat glands that focally destroy their basement membrane. PLF was diagnosed based on histological and immunohistochemical studies. In the multiple studies and case reports, the variability of the initial clinical diagnosis never corresponds to PLF, becoming a pathology with a low suspect index.

scholarly journals A Case Report of Yolk Sac Tumor in Cerebellar Hemisphere and Review of Literature

2020 ◽  
Author(s):  
Yuting Zhang ◽  
Lusheng Li ◽  
Ling He
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Case Reports ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
Cerebellar Hemisphere ◽  
Review Of Literature ◽  
Intracranial Germ Cell Tumor ◽  
The Right

Abstract Background: Yolk sac tumor also known as endodermal sinus tumor, is a rare intracranial germ cell tumor. We reported a case of yolk sac tumor in cerebellar hemisphere, and reviewed associated literatures. The majority of tumor locations are near the midline. On review of literature, very few case reports of intracranial yolk sac tumor have been published, and there is only one case report has described a yolk sac tumor arising from the cerebellum. Case presentation: A two years old boy admitted to our hospital due to headache and unsteady gait for six days. CT and MRI demonstrated a tumor in the right cerebellar hemisphere, and the blood and cerebrospinal fluid alpha-fetoprotein were found increased. It was diagnosed as yolk sac tumor after operation comfirmed by histopathological examination. Postoperative chemotherapy was performed, and the patient suffered no tumor recurrence one year and a half after the surgery. Conclusions: The clinical characteristics and imaging diagnosis of intracranial yolk sac tumor are lack of specificity, the comfirmed diagnosis is depending on the combination of elevated alpha-fetoprotein and histopathological examination.

Aggressive Cushing disease five years after the treatment of a nonfunctional pituitary adenoma

2016 ◽  
Vol 62 (5) ◽  
pp. 77-78
Author(s):  
Minodora Betivoiu ◽  
Sorina Martin ◽  
Iulia Soare ◽  
Alexandra Nila ◽  
Simona Fica
Keyword(s):  
Pituitary Adenoma ◽  
Gamma Knife ◽  
Pituitary Adenomas ◽  
Histopathological Examination ◽  
Case Reports ◽  
Dependent Diabetes Mellitus ◽  
Ki 67 ◽  
The Right ◽  
Gamma Knife Therapy

Introduction. Cushing's disease (CD) represents 10%–12% of all pituitary adenomas and is seen predominantly in women, with a female-to-male ratio of 8:1. Although most patients with ACTH-secreting adenomas present with benign, small tumors, some have invasive macroadenomas. Rarely, nonfunctional pituitary adenomas (NFPAs) may gain secretory function, but there have been a few case reports of metamorphosis to CD.Case report. We report the case of a 59-year-old female diagnosed in 2007 with a NFPA and panhypopituitarism. She had two transsphenoidal surgeries and Gamma Knife therapy and started replacement treatment with levothyroxine 75mcg/day and prednisone 5mg/day. The postoperative course was favorable and imagistic follow-up between 2007-2014 showed progressive reduction of the residual tumor and empty sella. From personal history we note noninsulin-dependent diabetes mellitus, postmenopausal osteoporosis treated with bisphosphonates. In January 2015 she suffered visual loss on the right eye. Pituitary MRI showed supra and parasellar tumor recurrence of 27/24/17mm, infiltrating the right side of the cavernous sinus, extending around the right internal carotid artery and optic nerve, compressing the optic chiasm. In March 2015 a third transsphenoidal partial excision of the tumor was performed and in August Gamma Knife therapy was repeated. The histopathological examination was consistent with a pituitary adenoma but immunohistochemical staining for ACTH was positive, with Ki-67=25%. She had no non-specific cushingoid features. Laboratory test: glucose=116mg/dl, HbA1c=7.5%, FSH=3.34mIU/ml, LH=0.585mIU/ml TSH=0.044mcIU/ml, FT4=1.13ng/dl. Prednisone replacement therapy was stopped and CD was confirmed: 8AMcortisol=13.3mcg/dl, 23PMcortisol=11.3mcg/dl, ACTH=70.2pg/ml, 8AMcortisol after 1mg dexamethasone overnight=13.8mcg/dl. Ophthalmic exam: blindness in the right eye, slightly decreased visual field in the left eye. Pituitary MRI 8-month postsurgery revealed a 28/31/28mm invasive tumor. We started treatment with Cabergoline 3mg/week and recommended closely biological and imagistic follow-up, hoping for a good response to radiotherapy.Conclusions: Our case stresses the importance of regular, lifelong follow-up of patients with NFPAs. Chiloiro et al have reported that pituitary adenomas with Ki-67≥1.5% have a higher risk of recurrence. Although the characteristics of patients with CD have been well known for decades, the diagnosis and management of this disease are often challenging.

scholarly journals Two Late Recurrences of Conjunctival Melanoma

2018 ◽  
Vol 5 (4) ◽  
pp. 262-266 ◽  
Author(s):  
Niels J. Brouwer ◽  
Stijn W. Genders ◽  
Marina Marinkovic ◽  
Sjoerd G. van Duinen ◽  
Martine J. Jager ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Surgical Procedures ◽  
Histopathological Examination ◽  
Orbital Exenteration ◽  
Conjunctival Melanoma ◽  
Inferior Margin ◽  
Primary Acquired Melanosis ◽  
The Right ◽  
Additional Therapy

Purpose: To report a patient who developed two late recurrences of conjunctival melanoma (CoM), of which one occurred after orbital exenteration. Methods: We describe the case of a patient based on clinical and histopathological examination. Results: A 52-year-old patient was treated with local excision and cryotherapy for a CoM with primary acquired melanosis (PAM) near the limbus of the right eye. Twenty-one years later, a recurrence developed in the superior fornix of the same eye in an area with widespread PAM; an orbital exenteration was performed. After another 4 years, a painful nodule developed subcutaneously at the inferior margin of the right orbital socket. Pathology showed a recurrence of CoM with a BRAF V600K mutation, similar to both of the previous lesions (of 25 and 4 years earlier). The nodule was excised without additional therapy. No recurrences or metastases have been observed in the next 2.5 years. The proposed mechanism for the recurrence after surgery could be via dormant tumor cells that have spread prior to the procedure or via residual intraepithelial malignant melanocytes. Conclusion: Very late recurrences of CoM are rare but may occur. Our case illustrates the need for long-term awareness of doctors and patients, even after extensive surgical procedures such as orbital exenteration.

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