Islamic law is concerned with treating infectious diseases by preventing them and limiting their spread, and it has indicated that the primary responsibility rests with the individual, so it obliges him to do everything that would limit the transmission of these epidemics, and the state is also responsible for providing everything that would limit these diseases and prevent their spread Such as imposing quarantine and providing medical and health care to those who have been afflicted by God with these diseases, and there is no doubt that infectious diseases some of them lead to the death of those who are infected with them, as in the Corona pandemic, and it is known that self-preservation is one of the most important objectives of Islamic law. Therefore, preventive measures must be taken into account. It can prevent the transmission of diseases and stop their spread. The jurists and scholars must explain to people the matters of their religion and world so that some of them do not fall into what is forbidden according to Sharia, so that they will be sinned by ignorance and without knowledge. The importance and reasons for choosing this topic comes in light of the spread of epidemics from time to time, the last of which is the Corona pandemic that has spread and afflicted many Muslims and some of them are ignorant of the jurisprudential rulings related to these epidemics such as the rule of non-compliance with the quarantine and the ruling on the transmission of infection intentionally and ignorant, as well as preventive measures Islamic law that limits the spread of these epidemics. Among the results that we reached in our research is that we have proven the transmission of infection, and it is a constant occurrence in our Islamic history and there is no room for denying it, so it is not permissible to deliberately transmit the infectious disease to healthy people and it is one of the major sins that entails God’s punishment in the hereafter and retribution in this world. Ignorance and negligence of wrongdoing without intending there is no sin on him in the hereafter, but he must guarantee what he destroys in this world, because Islamic law has taken a group of them: the dislike of blowing into a bowl, the prohibition of spitting on the ground, and the necessity of purification from the impurity of some animals such as dogs and pigs that transmit diseases to humans Preventing defecation and urination in public resources, and many measures that prevent the transmission of diseases and limit them.