Progress and perspectives in total body PET systems instrumentation

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Stefaan Vandenberghe

Abstract Total body positron emission tomography (PET) systems are being developed by different groups worldwide. These systems have potential to change the number of applications in which molecular imaging is used. The change from a short axial field of view (FOV) to a longer one is however associated with a linear increase in the cost of these systems. This may limit their application to a small number of centers (capable of obtaining sufficient research funding). Therefore it remains interesting to see if lower cost systems can be developed and bring total body PET to the clinic for an acceptable budget. The wider availability of this low cost system can also enable more researchers to further optimize and explore the full potential of total body PET.

Author(s):  
Lucian T. Grigorie ◽  
Ruxandra M. Botez

In this paper, an algorithm for the inertial sensors errors reduction in a strap-down inertial navigation system, using several miniaturized inertial sensors for each axis of the vehicle frame, is conceived. The algorithm is based on the idea of the maximum ratio-combined telecommunications method. We consider that it would be much more advantageous to set a high number of miniaturized sensors on each input axis of the strap-down inertial system instead of a single one, more accurate but expensive and with larger dimensions. Moreover, a redundant system, which would isolate any of the sensors in case of its malfunctioning, is obtained. In order to test the algorithm, Simulink code is used for algorithm and for the acceleration inertial sensors modeling. The Simulink resulted sensors models include their real errors, based on the data sheets parameters, and were conceived based on the IEEE analytical standardized accelerometers model. An integration algorithm is obtained, in which the signal noise power delivered to the navigation processor, is reduced, proportionally with the number of the integrated sensors. At the same time, the bias of the resulted signal is reduced, and provides a high redundancy degree for the strap-down inertial navigation system at a lower cost than at the cost of more accurate and expensive sensors.


2014 ◽  
pp. 319-346
Author(s):  
Salahuddin Qazi ◽  
Farhan A. Qazi

Solar radiation is plentiful and a clean source of power. However, despite the first practical use of silicon based solar cell more than 50 years ago, it has not been exploited to its full potential due to the high cost of electrical conversion on a per Watt basis. Many new kinds of photovoltaic cells such as multi-junction solar cells dye –sensitized solar cells and organic solar cell incorporating element of nanotechnology have been proposed to increase the efficiency and reduce the cost. Nanotechnology, in the form of quantum dots, nanorods, nanotubes, and grapheme, has been shown to enhance absorption of sunlight, makes low cost flexible solar panels and increases the efficiency of photovoltaic cells. The chapter reviews the state of current photovoltaic cells and challenges it presents. It also discusses the use of nanotechnology in the application of photovoltaic cells and future research directions to improve the efficiency of solar cells and reduce the cost.


Author(s):  
Salahuddin Qazi ◽  
Farhan A. Qazi

Solar radiation is plentiful and a clean source of power. However, despite the first practical use of silicon based solar cell more than 50 years ago, it has not been exploited to its full potential due to the high cost of electrical conversion on a per Watt basis. Many new kinds of photovoltaic cells such as multi-junction solar cells dye –sensitized solar cells and organic solar cell incorporating element of nanotechnology have been proposed to increase the efficiency and reduce the cost. Nanotechnology, in the form of quantum dots, nanorods, nanotubes, and grapheme, has been shown to enhance absorption of sunlight, makes low cost flexible solar panels and increases the efficiency of photovoltaic cells. The chapter reviews the state of current photovoltaic cells and challenges it presents. It also discusses the use of nanotechnology in the application of photovoltaic cells and future research directions to improve the efficiency of solar cells and reduce the cost.


2012 ◽  
Vol 457-458 ◽  
pp. 1377-1382
Author(s):  
Yu Jie Chen ◽  
Cong Hu ◽  
Yi Ze Sun ◽  
Zhuo Meng

For a determination of the system’s efficiency and decrease the cost, a low cost system for measuring solar irradiance is designed. By analyzing the influence of solar irradiance and temperature to solar cell, we have found that in case of different temperatures the variation of short-circuit current (Isc) in function of solar irradiation incident (E) is always linear. Then the read-out circuitry is designed to measure and convert the signal which is detected by the photoelectric cell and thermocouples. At last, the software is developed to compensate the temperature and make sure the device work normally. The results of detecting the system show that it’s effective and reliable.


2014 ◽  
Vol 541-542 ◽  
pp. 1297-1303
Author(s):  
Kheddar Boudjemaa ◽  
Ping Song

This paper presents a design and implementation of an efficient and low cost system for indoor monitoring of human intrusion. The system design is based on the use of already available pyroelectric infrared passive sensors (PIR) that are able to detect thermal perturbation caused by moving objects within their field of view (FOV). Our design uses the PIR sensors in the geometric context as binary detectors with adaptive threshold estimation. The combined field of view of three PIR detectors is modulated by a custom designed lens mask to estimate the bearing angle of the single human intrusion. The prototype is formed by a sensing module routed wirelessly to another host module to visualize processed raw data.


Author(s):  
John Dickson ◽  
Uta Eberlein ◽  
Michael Lassmann

Abstract Aim Recent advancements in PET technology have brought with it significant improvements in PET performance and image quality. In particular, the extension of the axial field of view of PET systems, and the introduction of semiconductor technology into the PET detector, initially for PET/MR, and more recently available long-field-of-view PET/CT systems (≥ 25 cm) have brought a step change improvement in the sensitivity of PET scanners. Given the requirement to limit paediatric doses, this increase in sensitivity is extremely welcome for the imaging of children and young people. This is even more relevant with PET/MR, where the lack of CT exposures brings further dose reduction benefits to this population. In this short article, we give some details around the benefits around new PET technology including PET/MR and its implications on the EANM paediatric dosage card. Material and methods  Reflecting on EANM adult guidance on injected activities, and making reference to bed overlap and the concept of MBq.min bed−1 kg−1, we use published data on image quality from PET/MR systems to update the paediatric dosage card for PET/MR and extended axial field of view (≥ 25 cm) PET/CT systems. However, this communication does not cover the expansion of paediatric dosing for the half-body and total-body scanners that have recently come to market. Results In analogy to the existing EANM dosage card, new parameters for the EANM paediatric dosage card were developed (class B, baseline value: 10.7 MBq, minimum recommended activity 10 MBq). The recommended administered activities for the systems considered in this communication range from 11 MBq [18F]FDG for a child with a weight of 3 kg to 149 MBq [18F]FDG for a paediatric patient weight of 68 kg, assuming a scan of 3 min per bed position. The mean effective dose over all ages (1 year and older) is 2.85 mSv. Conclusion With this, recommendations for paediatric dosing are given for systems that have not been considered previously.


2020 ◽  
pp. jnumed.120.250597 ◽  
Author(s):  
Benjamin A. Spencer ◽  
Eric Berg ◽  
Jeffrey P. Schmall ◽  
Negar Omidvari ◽  
Edwin K. Leung ◽  
...  

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Duangthip Trisrivirat ◽  
John M X Hughes ◽  
Robin Hoeven ◽  
Matthew Faulkner ◽  
Helen Toogood ◽  
...  

Abstract Successful industrial biotechnological solutions to biofuels and other chemicals production rely on effective competition with existing lower-cost natural sources and synthetic chemistry approaches enabled by adopting low-cost bioreactors and processes. This is achievable by mobilizing Halomonas as a next generation industrial chassis, which can be cultivated under non-sterile conditions. To increase the cost effectiveness of an existing sustainable low carbon bio-propane production strategy, we designed and screened a constitutive promoter library based on the known strong porin promoter from Halomonas. Comparative studies were performed between Escherichia coli and Halomonas using the reporter gene red fluorescent protein (RFP). Later studies with a fatty acid photodecarboxylase-RFP fusion protein demonstrated tuneable propane production in Halomonas and E. coli, with an ∼8-fold improvement in yield over comparable isopropyl-β-D-thiogalactoside-inducible systems. This novel set of promoters is a useful addition to the synthetic biology toolbox for future engineering of Halomonas to make chemicals and fuels.


2007 ◽  
Vol 2007 ◽  
pp. 140-140 ◽  
Author(s):  
T.W.J. Keady ◽  
J.P. Hanrahan

Recent studies at this centre (Flanagan 2003, Keady et al. 2006) have shown that grazing swards in the winter (extended grazing), either in mid, late or throughout pregnancy, provides a low-cost system for wintering ewes. With decoupling of subsidy from production post Mid Term Review of the Common Agricultural Policy it is essential to improve efficiency and reduce costs of production. One of the major costs in sheep production is the cost of rearing replacements. The aim of the present study was to evaluate the effect of herbage allowance and concentrate supplementation on animal performance during extended grazing and on compensatory growth during the subsequent grazing season. Furthermore the potential herbage allowance sparing effect of concentrate supplementation was also determined.


2021 ◽  
Vol 3 (144) ◽  
pp. 94-99
Author(s):  
Vyacheslav F. Aulov ◽  
◽  
Yuriy N. Rozhkov ◽  
Valentin P. Lyalyakin

The main goal of agriculture is to obtain products, but its processing is no less important. At processing enterprises, grinding and cutting are the most important technological process. (Research purpose) The research purpose is in analyzing the market of knives of processing machines, their pricing, resource and describing the economic efficiency of applying strengthening coatings. (Materials and methods) Authors used a digital method of searching through the Internet for enterprises that produce knives for processing machines, types of knives and their characteristics. (Results and discussion) Specialized knives are used for grinding products in the industrial plants. Since knives are a consumable item, the technology of their replacement is subject to requirements for the simplicity of the process, low cost and low labor cost. These requirements, together with the specific ones determined by the technology, form the design of the knives. The efficiency of the processing machine directly depends on the state of its working organs. Replacement of worn-out elements is accompanied by large labor costs, which leads to a decrease in labor productivity and to downtime of equipment in repair, and ultimately − to a decrease in the profit of the enterprise. (Conclusions) The hardening of knives by the borating method using high-frequency heating will increase the productivity of agricultural machinery and will give an economic effect up to 0.32 billion rubles due to an increase in the resource and a lower cost of manufacturing hardened knives compared to imported ones. By reducing the cost of domestic knives, you can get savings on one knife of 1960 rubles, provided that you refuse to purchase imported knives.


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