scholarly journals Intraoperative identification of somato-sensory brain areas using optical imaging and standard RGB camera equipment – a feasibility study

2015 ◽  
Vol 1 (1) ◽  
pp. 265-269
Author(s):  
M. Oelschlägel ◽  
T. Meyer ◽  
S. B. Sobottka ◽  
M. Kirsch ◽  
G. Schackert ◽  
...  

AbstractIntraoperative Optical Imaging (IOI) is a neuro-imaging technique that allows the visualization of changes in optical properties of the brain cortex. Recent developments enhanced the method regarding the robustness under intraoperative conditions. However, the necessity of additional hardware still limits the use in the operating room (OR). Since modern surgical microscopes are potentially equipped with all required hardware for imaging, we investigated the possible use of such standard RGB camera for IOI. Measurements were performed on eight patients. Changes in optical properties of the cortical surface were acquired with a monochrome CCD camera (AxioCam MRm) and simultaneously with a standard RGB camera (Trio 610). Maps of cortical activity were calculated from the image data and the quality of these maps was assessed with a spatial signal-to-noise ratio. Activity maps calculated from AxioCam MRm data showed highest SNR in six out of eight patients. In two patients the activity map calculated from Trio 610 red channel performed best overall. The Trio 610 maps calculated from red channel data performed best in three out of eight cases like the activity maps calculated from green channel data, whereas the activity map calculated from blue channel data performed best in only two cases. If the color channel with the highest SNR is chosen in each patient for comparison to AxioCam MRm, the median of the SNR (SNRAxioCam/SNRBestColorChannel) is 84 % (Quartile 1 (Q1): 78 %, Quartile 3 (Q3): 99%). Results reveal that the integration of the Intraoperative Optical Imaging method into the OR and surgical workflow can be further improved by using RGB camera equipment. A robust identification of somato-sensory areas seems possible. Due to the gain of information from different wavelength bands the need for intelligent evaluation algorithms is increased and should therefore be topic of future research.

2021 ◽  
Vol 23 (1) ◽  
pp. 148-166
Author(s):  
Yu. Agalidi ◽  
O. Koshel

While research on destroyed relief marking of metal objects using the magneto-optical method, visualization of (invisible) fields of internal stress in the VIN plate area is performed and then a forensic analysis of obtained instrumental data is carried out (indirect organoleptic observation of the visualization results); thus, forensic analysis reliability of results directly depends on sensitivity of instruments and informativeness of instrumental data. The main quantitative characteristic in this case is probability of correct signal recognition  (contours of marking signs) against the background of noise (structural noise of investigated surface and the noise of the visualization method itself) determined by the signal-to-noise ratio. This article presents results of a comparative experimental assessment of signal-to-noise ratio and probability of correct signal recognition while restoringthe destroyed relief markings for two complexes of magneto-optical imaging – models of 2006 and 2018. This article purpose is a quantitative and qualitative comparative assessment of results of visualization of internal stresses in areas of completely removed relief marking of metal objects. The results of successful practical research obtained by forensic experts from different countries make it possible to assess effectiveness and prospects of using the magneto-optical imaging method. In a new modification of the magneto-optical complex: signal level is 4.35 dB higher (contrast of reconstructed marking signs); 2.71 dB lower noise level (surface relief/texture and magnetic copying noise);• probability of correct character recognition is P> 0.995 (increased by 14.9%). Technical improvements in implementation of magneto-optical visualization method made it possible to expand the range of materials for research objects(magnetic and electrically conductive materials were investigated). The high efficiency of method for restoring marking is illustrated by results of forensic examinations for materials with a low level of residual stresses (aluminum alloy, low-carbon steel) which  chemical etching method did not give results for. The use of new modification allows examining the rust layer, up to cases of corrosion to the entire depth of marks. Considering non-destructive nature of magneto-optical researches, possibility of their repeated repetition without losing  object properties, this method (in accordance with the order of application of types of studies) deserves more attention for application.


Proceedings ◽  
2020 ◽  
Vol 60 (1) ◽  
pp. 44
Author(s):  
Anais Gómez ◽  
Diana Bueno ◽  
Juan Manuel Gutiérrez

The present work reports the potential of a bio-inspired system based on spectrometry, also known as Electronic Eye (EE), capable of detecting different Tequila samples. The reported system analyzes small volumes of Tequila Reposado and Blanco by calculating samples’ absorbances, using a low cost and portable instrumentation employing a CCD camera. The absorbance imaging method consisted of exciting samples with light passes through an 8MP camera connected to a Raspberry Pi Card. The camera’s image data are analyzed using MATLAB 2018b to be represented in Red, Green and Blue (RGB) components for each pixel, in order to get an approximation of the absorbance and the Surface Color Index (Isc) associated with sample concentration. Using the developed EE, it was possible to identify seven different kinds and brands of Tequila. From the obtained results, it was observed that the average absorbance of the Tequila Reposado was greater than the absorbance of the Tequila Blanco. Otherwise, with the Isc, the Tequila Blanco color index is lower concerning the Tequila Reposado’s. Finally, the EE allowed the identification of Tequila samples with reproducibility and repeatability.


Author(s):  
Robert W. Mackin

This paper presents two advances towards the automated three-dimensional (3-D) analysis of thick and heavily-overlapped regions in cytological preparations such as cervical/vaginal smears. First, a high speed 3-D brightfield microscope has been developed, allowing the acquisition of image data at speeds approaching 30 optical slices per second. Second, algorithms have been developed to detect and segment nuclei in spite of the extremely high image variability and low contrast typical of such regions. The analysis of such regions is inherently a 3-D problem that cannot be solved reliably with conventional 2-D imaging and image analysis methods.High-Speed 3-D imaging of the specimen is accomplished by moving the specimen axially relative to the objective lens of a standard microscope (Zeiss) at a speed of 30 steps per second, where the stepsize is adjustable from 0.2 - 5μm. The specimen is mounted on a computer-controlled, piezoelectric microstage (Burleigh PZS-100, 68/μm displacement). At each step, an optical slice is acquired using a CCD camera (SONY XC-11/71 IP, Dalsa CA-D1-0256, and CA-D2-0512 have been used) connected to a 4-node array processor system based on the Intel i860 chip.


2001 ◽  
Vol 66 (6) ◽  
pp. 973-982 ◽  
Author(s):  
Čestmír Koňák ◽  
Jaroslav Holoubek ◽  
Petr Štěpánek

A time-resolved small-angle light scattering apparatus equipped with azimuthal integration by means of a conical lens or software analysis of scattering patterns detected with a CCD camera was developed. Averaging allows a significant reduction of the signal-to-noise ratio of scattered light and makes this technique suitable for investigation of phase separation kinetics. Examples of applications to time evolution of phase separation in concentrated statistical copolymer solutions and dissolution of phase-separated domains in polymer blends are given.


Nanophotonics ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
María Taeño ◽  
David Maestre ◽  
Ana Cremades

Abstract Nickel oxide (NiO) is one of the very few p-type semiconducting oxides, the study of which is gaining increasing attention in recent years due to its potential applicability in many emerging fields of technological research. Actually, a growing number of scientific works focus on NiO-based electrochromic devices, high-frequency spintronics, fuel cell electrodes, supercapacitors, photocatalyst, chemical/gas sensors, or magnetic devices, among others. However, less has been done so far in the development of NiO-based optical devices, a field in which this versatile transition metal oxide still lags in performance despite its potential applicability. This review could contribute with novelty and new forefront insights on NiO micro and nanostructures with promising applicability in optical and optoelectronic devices. As some examples, NiO lighting devices, optical microresonators, waveguides, optical limiters, and neuromorphic applications are reviewed and analyzed in this work. These emerging functionalities, together with some other recent developments based on NiO micro and nanostructures, can open a new field of research based on this p-type material which still remains scarcely explored from an optical perspective, and would pave the way to future research and scientific advances.


2021 ◽  
Vol 19 (3) ◽  
pp. 235-285
Author(s):  
Mason D. Lancaster

This article provides an overview of metaphor theories and research on their own terms, as well as their use in Hebrew Bible (HB) studies. Though metaphor studies in the HB have become increasingly popular, they often draw upon a limited or dated subset of metaphor scholarship. The first half of this article surveys a wide variety of metaphor scholarship from the humanities (philosophical, poetic, rhetorical) and the sciences (e.g., conceptual metaphor theory), beginning with Aristotle but focusing on more recent developments. The second half overviews studies of metaphor in the HB since 1980, surveying works focused on theory and method; works focused on specific biblical books or metaphor domains; and finally noting current trends and suggesting areas for future research.


2019 ◽  
Vol 10 (3) ◽  
pp. 686-707
Author(s):  
Marcus Conlé

Purpose The paper aims to take stock of China’s recent biopharmaceutical industry development by analyzing product innovation and changes in the firms’ product portfolios during the five-year period between 2012 and 2017. Design/methodology/approach The paper introduces a classification of biopharmaceutical products. By applying the classification to the product data of China’s drug regulator, the CFDA, it becomes possible to trace the developments within the sector by looking at changes in the number of firms within each subgroup and changes in the number of subgroups in which each firm is involved. The classification allows an evaluation of the latest product innovation achievements. Findings The paper demonstrates a mild shakeout of firms in the relatively long-existing domestic market segments, a trend toward more specialized product portfolios and an enduring prevalence of innovation strategies aimed at exploiting relatively unpopulated domestic market niches instead of pioneering entirely new products. Especially the capability of upgrading to second-generation protein therapeutics has become a key criterion for separating the wheat and the chaff in China’s domestic sector. The paper moreover points out the relevance of acquisitions as a corporate growth strategy. Research limitations/implications The research does not consider complementary indicators, product pipelines in particular. Future research should compare patterns across emerging economies. Originality/value The paper is unique in using the CFDA database for systematic academic research on (bio)pharmaceutical innovation and in introducing a biopharmaceutical product classification to trace innovative activities and changes in corporate product portfolios over time.


2009 ◽  
Vol 17 (26) ◽  
pp. 24403 ◽  
Author(s):  
Elizabeth J. Sutton ◽  
Sophie E. Boddington ◽  
Alexander J. Nedopil ◽  
Tobias D. Henning ◽  
Stavros G. Demos ◽  
...  

Telecom ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 167-180
Author(s):  
George K. Varotsos ◽  
Hector E. Nistazakis ◽  
Konstantinos Aidinis ◽  
Fadi Jaber ◽  
Mohd Nasor ◽  
...  

Recent developments in both optical wireless communication (OWC) systems and implanted medical devices (IMDs) have introduced transdermal optical wireless (TOW) technology as a viable candidate for extremely high-speed in-body to out-of-body wireless data transmissions, which are growing in demand for many vital biomedical applications, including telemetry with medical implants, health monitoring, neural recording and prostheses. Nevertheless, this emerging communication modality is primarily hindered by skin-induced attenuation of the propagating signal bit carrier along with its stochastic misalignment-induced fading. Thus, by considering a typical modulated retroreflective (MRR) TOW system with spatial diversity and optimal combining (OC) for signal reception in this work, we focus, for the first time in the MRR TOW literature, on the stochastic nature of generalized pointing errors with non-zero boresight (NZB). Specifically, under these circumstances, novel analytical mathematical expressions were derived for the total average bit error rate (BER) of various system configurations. Their results revealed significant outage performance enhancements when spatial diversity was utilized. Moreover, taking into consideration the total transdermal pathloss along with the effects of stochastic NZB pointing errors, the critical average signal-to-noise ratio (SNR) metric was evaluated for typical power spectral-density values.


2021 ◽  
Vol 13 (1) ◽  
pp. 19-35
Author(s):  
Baile Lu ◽  
Shuai Hao ◽  
Michael Pinedo ◽  
Yuqian Xu

In this paper, we provide a survey of recent developments in the fintech (financial technology) industry, focusing on the operational structures, the technologies involved, and the operational risks associated with the new systems. In particular, we discuss payment systems, algorithmic trading, robo-advisory, crowdfunding, and peer-to-peer lending. In the conclusion section, we discuss various promising research directions.


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