scholarly journals Biomechanical parameter determination of scaffold-free cartilage constructs (SFCCs) with the hyperelastic material models Yeoh, Ogden and Demiray

2015 ◽  
Vol 1 (1) ◽  
pp. 442-445 ◽  
Author(s):  
T. Reuter ◽  
I. Ponomarev
Keyword(s):  
Articular Cartilage ◽  
Functional Characterization ◽  
Three Dimensional ◽  
Material Model ◽  
Biomechanical Properties ◽  
Hyperelastic Material ◽  
Parameter Determination ◽  
Material Models ◽  
Normalized Error ◽  
Two Parameters

AbstractThe biomechanical properties are crucial indicators for the functional characterization of cartilaginous tissue. In this contribution native articular cartilage and three-dimensional scaffold-free cartilage constructs (SFCCs) are characterized by hyperelastic material models (Yeoh, Ogden and Demiray). SFCCs were developed for the therapy of damaged articular cartilage. The normalized error (NE) of fit and experiment is in the range of 0.04 and 0.13. The material model Yeoh with two parameters yields the best fit. The stress-like parameterc20 is 0.489 MPa for native cartilage, 0.120 MPa and 0.041 MPa for SFCCs produced from mesenchymal stem cells and chondrocytes, respectively. The significance of the fits and the derived parameters are presented and evaluated.

scholarly journals Variation of Passive Biomechanical Properties of the Small Intestine along Its Length: Microstructure-Based Characterization

2021 ◽  
Vol 8 (3) ◽  
pp. 32
Author(s):  
Dimitrios P. Sokolis
Keyword(s):  
Small Intestine ◽  
Orientation Angle ◽  
Axial Direction ◽  
Material Model ◽  
Biomechanical Properties ◽  
Intestinal Wall ◽  
Model Parameters ◽  
Material Models ◽  
Hyper Elastic ◽  
Rat Tissue

Multiaxial testing of the small intestinal wall is critical for understanding its biomechanical properties and defining material models, but limited data and material models are available. The aim of the present study was to develop a microstructure-based material model for the small intestine and test whether there was a significant variation in the passive biomechanical properties along the length of the organ. Rat tissue was cut into eight segments that underwent inflation/extension testing, and their nonlinearly hyper-elastic and anisotropic response was characterized by a fiber-reinforced model. Extensive parametric analysis showed a non-significant contribution to the model of the isotropic matrix and circumferential-fiber family, leading also to severe over-parameterization. Such issues were not apparent with the reduced neo-Hookean and (axial and diagonal)-fiber family model, that provided equally accurate fitting results. Absence from the model of either the axial or diagonal-fiber families led to ill representations of the force- and pressure-diameter data, respectively. The primary direction of anisotropy, designated by the estimated orientation angle of diagonal-fiber families, was about 35° to the axial direction, corroborating prior microscopic observations of submucosal collagen-fiber orientation. The estimated model parameters varied across and within the duodenum, jejunum, and ileum, corroborating histologically assessed segmental differences in layer thicknesses.

scholarly journals COMPARISON OF VIRTUAL FIELDS METHOD, PARALLEL NETWORK MATERIAL MODEL AND FINITE ELEMENT UPDATING FOR MATERIAL PARAMETER DETERMINATION

2016 ◽  
Vol 7 ◽  
pp. 7
Author(s):  
Florian Dirisamer ◽  
Umut D. Çakmak ◽  
Imre Kállai ◽  
Martín Machado ◽  
Zoltán Major
Keyword(s):  
Finite Element ◽  
Material Model ◽  
Image Correlation ◽  
Parameter Determination ◽  
Virtual Fields Method ◽  
Material Models ◽  
Time Frequency ◽  
Parallel Network ◽  
Experimental Effort ◽  
Frequency Temperature

Extracting material parameters from test specimens is very intensive in terms of cost and time, especially for viscoelastic material models, where the parameters are dependent of time (frequency), temperature and environmental conditions. Therefore, three different methods for extracting these parameters were tested. Firstly, digital image correlation combined with virtual fields method, secondly, a parallel network material model and thirdly, finite element updating. These three methods are shown and the results are compared in terms of accuracy and experimental effort.

Buckling and Postbuckling of Elastomeric Components: Tactile Feel in Electric Switches

1990 ◽  
Vol 63 (1) ◽  
pp. 135-148 ◽  
Author(s):  
Joe Padovan ◽  
Mark Schrader ◽  
Joel Parris
Keyword(s):  
Three Dimensional ◽  
Intrinsic Property ◽  
Material Model ◽  
Fe Analysis ◽  
Dimensional Model ◽  
Three Dimensional Model ◽  
Material Models ◽  
Switch Structure ◽  
Switch Design ◽  
Traditional Structures

Abstract Within the range of the parameters of the switch designs considered, only very slight cocking of the switch structure occurred. Thus, with minimal off-axis cocking, the axisymmetric assumption remained valid, resulting in a considerable finite-element economization when compared to a full three dimensional model. Some switch designs encounter localization problems, such as surface folding and stiffness mismatches. Mesh refinement is not a general panacea for these localization problems. Regardless, a fold of this type or stiffness mismatch is generally indicative of a potentially poor switch design, with the possibility of associated fatigue problems. For the switch designs considered, the peak strains were found to be less than 70 percent; thus the Mooney-Rivlin and Ogden material models yielded essentially similar results. Furthermore, a Hookean material model may be adequate for some purposes, because the tactile-feel response was found to be dominated more by switch geometry than anything else. Overall, we have seen that combining FE analysis together with the full continuum-constitutive-boundary formulation can successfully address the problem of buckling and postbuckling of elastomeric structures. In the case of switches, such behavior is an intrinsic property. This is an interesting contrast with traditional structures.

scholarly journals New Analytical Model for Swellable Materials

2021 ◽  
Author(s):  
Sayyad Zahid Qamar ◽  
Maaz Akhtar ◽  
Tasneem Pervez
Keyword(s):  
Finite Element ◽  
Three Dimensional ◽  
Hyperelastic Material ◽  
Behavior Patterns ◽  
Material Models ◽  
Maximum Resistance ◽  
New Models ◽  
Major Shortcoming ◽  
Gaussian Statistics ◽  
Solvent Molecules

As discussed in Chapter 6, numerical prediction of swelling can be attempted using existing hyperelastic material models available in commercial finite element (FE) packages. However, none of these models can accurately represent the behavior of swelling elastomers. The major shortcoming of currently available swelling models is that they consider Gaussian statistics for mechanical contribution of configuration entropy, which is based on chains having limited extensibility. Some later models (not yet incorporated into commercial FE packages) can give a reasonable account of certain behavior patterns in swelling elastomers, but do not explain other aspects well. One of the new approaches is to treat swelling elastomers as gels. As described earlier, gels are mostly liquid, yet they behave like solids due to a three-dimensional cross-linked network within the liquid. Many authors consider gel as poro-elastic or porous and use Darcy’s law to model the amount of fluid influx. However, a swollen elastomer mostly consists of the solvent. When an external load is applied, maximum resistance comes from the solvent molecules as in diffusion. Also, most of the new models are quite complex in concept and formulation, and there is a serious need for a scientifically simpler model.

scholarly journals Possible use of the hyperelastic material models in numerical analysis of the wood-strand mat compression

2009 ◽  
Vol 57 (4) ◽  
pp. 83-94
Author(s):  
Václav Sebera ◽  
Jan Tippner
Keyword(s):  
Numerical Analysis ◽  
Contact Pressure ◽  
Degrees Of Freedom ◽  
Material Model ◽  
Hyperelastic Material ◽  
Computational System ◽  
Material Models ◽  
Pressing Process ◽  
Hyperelastic Model ◽  
Wood Strand

The main goal of the work was to evaluate a possibility of using various hyperelastic material mo­dels implemented into ANSYS computational system for the numerical analysis of wood-strand mat pressing or wood-based composites. Subsequently, the most suitable hyperelastic model was used as a material model in compression simulation. Pressing itself was modelled as a contact transient ana­ly­sis with wood-strand mat being defined as a homogenous and isotropic continuum with the chosen material model. In the analysis only displacement degrees of freedom are considered. Output of the simulation is a contact pressure, which is necessary to apply to compress the mat on the required height. The analysis serves as a take-off platform for further research in wood-based com­po­si­tes pressing process.

Applications of Scanning Microscopy in Biomedical Research

1968 ◽  
Vol 26 ◽  
pp. 354-355
Author(s):  
T. L. Hayes
Keyword(s):  
Information Content ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Dental Enamel ◽  
Resolving Power ◽  
Whole Mount ◽  
Two Parameters ◽  
Content Information ◽  
Sectioned Tissue

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.

scholarly journals A composite scaffold of Wharton’s jelly and chondroitin sulphate loaded with human umbilical cord mesenchymal stem cells repairs articular cartilage defects in rat knee

2021 ◽  
Vol 32 (4) ◽  
Author(s):  
Zhong Li ◽  
Yikang Bi ◽  
Qi Wu ◽  
Chao Chen ◽  
Lu Zhou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Articular Cartilage ◽  
Composite Scaffold ◽  
Biomechanical Properties ◽  
Cartilage Defects ◽  
Human Umbilical Cord ◽  
Composite Scaffolds ◽  
Articular Cartilage Defects

AbstractTo evaluate the performance of a composite scaffold of Wharton’s jelly (WJ) and chondroitin sulfate (CS) and the effect of the composite scaffold loaded with human umbilical cord mesenchymal stem cells (hUCMSCs) in repairing articular cartilage defects, two experiments were carried out. The in vitro experiments involved identification of the hUCMSCs, construction of the biomimetic composite scaffolds by the physical and chemical crosslinking of WJ and CS, and testing of the biomechanical properties of both the composite scaffold and the WJ scaffold. In the in vivo experiments, composite scaffolds loaded with hUCMSCs and WJ scaffolds loaded with hUCMSCs were applied to repair articular cartilage defects in the rat knee. Moreover, their repair effects were evaluated by the unaided eye, histological observations, and the immunogenicity of scaffolds and hUCMSCs. We found that in vitro, the Young’s modulus of the composite scaffold (WJ-CS) was higher than that of the WJ scaffold. In vivo, the composite scaffold loaded with hUCMSCs repaired rat cartilage defects better than did the WJ scaffold loaded with hUCMSCs. Both the scaffold and hUCMSCs showed low immunogenicity. These results demonstrate that the in vitro construction of a human-derived WJ-CS composite scaffold enhances the biomechanical properties of WJ and that the repair of knee cartilage defects in rats is better with the composite scaffold than with the single WJ scaffold if the scaffold is loaded with hUCMSCs.

scholarly journals Ovariectomy alters the structural and biomechanical properties of ovine femoro-tibial articular cartilage and increases cartilage iNOS

2005 ◽  
Vol 13 (12) ◽  
pp. 1066-1075 ◽  
Author(s):  
M.A. Cake ◽  
R.C. Appleyard ◽  
R.A. Read ◽  
M.M. Smith ◽  
G.A.C. Murrell ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Biomechanical Properties
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