The influence of thyroid disorders on bone density and biochemical markers of bone metabolism

2018 ◽  
Vol 35 (1) ◽  
Author(s):  
Konstantinos Tsevis ◽  
Eftihios Trakakis ◽  
Vasilios Pergialiotis ◽  
Eleni Alhazidou ◽  
Melpomeni Peppa ◽  
...  
Keyword(s):  
Bone Density ◽  
Bone Mass ◽  
Thyroid Function ◽  
Mass Density ◽  
Bone Mass Density ◽  
Thyroid Disorders ◽  
Increased Risk ◽  
Menopausal Women ◽  
Post Menopausal ◽  
The Impact

Abstract Background Thyroid dysfunction, predominantly hyperthyroidism, has been previously linked to impaired bone mass density (BMD) and increased risk of fractures. On the other hand, data in the field of hypothyroidism (HT) are missing. The purpose of the present study was to investigate the impact of thyroid disorders on bone density serum and urine calcium (Ca) and phosphate (P) as well as serum osteocalcin and alkaline phosphatase and urine hydroxyproline in a series of post-menopausal women. Materials and methods The study was conducted in the Reproductive Endocrinology Outpatient Clinic of our hospital. A consecutive series of post-menopausal women was included, after excluding patients under hormone treatment (including levothyroxine supplementation) and those who received raloxifene, tamoxifen or tibolone during the study period as well as those who received treatment during the previous 12 months were excluded from the present study. Results Overall, 188 women were included in the present study. Among them, 143 women had normal thyroid function, 32 women had hyperthyroidism and 13 women had HT. Correlation of thyroid function indices with osteoporosis indices revealed statistically significant correlations between thyroxine (T4) and free triiodothyronine (T3) with T-, Z-scores and BMD. Logistic regression analysis concerning the impact of HT and hyperthyroidism on T-score, Z-score and bone mass density revealed that both pathological entities negatively affect bone health (p < 0.05). Conclusion The findings of our study suggest that not only hyperthyroidism, but also HT negatively affects BMD. Future studies should investigate this association and corroborate our findings.

Calcaneal Bone Mass Modification in Recreational Runners

2016 ◽  
Vol 106 (6) ◽  
pp. 381-386 ◽  
Author(s):  
Elena Escamilla-Martínez ◽  
Alfonso Martínez-Nova ◽  
Beatriz Gómez-Martín ◽  
Raquel Sánchez-Rodríguez ◽  
Lourdes María Fernández-Seguín ◽  
...  
Keyword(s):  
Bone Density ◽  
Bone Mass ◽  
Mass Density ◽  
Control Sample ◽  
Bone Mass Density ◽  
Running Shoes ◽  
Negative Effect ◽  
Trabecular Bone Mass ◽  
Recreational Runners ◽  
The Impact

Background: The calcaneus is the bone of the foot that first receives the impact of running, generating vibrations that might have a positive effect in modifying the trabecular bone mass. The objective of this study was to determine the variation in calcaneal bone density in runners during a 6-month training season, comparing it with a control sample. Methods: Bone density of the heel was measured in 33 male recreational runners by means of a contact ultrasonic bone analyzer. Measurements were made on three occasions during a training season: at the beginning, at 350 km, and at 700 km. All of the runners wore the same model of running shoes during this period. Measurements of bone density were also made in a control sample of 62 men who did not engage in physical exercise. Results: There was a significant decrease in mean calcaneal bone density over the course of the training season (from 86.1 dB/MHz to 83.2 dB/MHz; P = .006), but no significant differences with the control sample value (from 80.7 dB/MHz to 81.1 dB/MHz; P = .314). The runners' body composition changed during the study period, with lean mass increasing and fat mass decreasing. Conclusions: Distance running seems to have a negative effect on calcaneal bone mass density during the course of a 700-km training season.

High bone-mass density as a marker for breast cancer in post-menopausal women

The Breast ◽  
2001 ◽  
Vol 10 (4) ◽  
pp. 313-317 ◽  
Author(s):  
O. Ganry ◽  
B. Tramier ◽  
P. Fardellone ◽  
N. Raverdy ◽  
A. Dubreuil
Keyword(s):  
Breast Cancer ◽  
Bone Mass ◽  
Mass Density ◽  
Bone Mass Density ◽  
High Bone Mass ◽  
Menopausal Women ◽  
High Bone ◽  
Post Menopausal

Bone mass density in post-menopausal women

1997 ◽  
Vol 58 (3) ◽  
pp. 287-291 ◽  
Author(s):  
E.V. Cosmi ◽  
M. Minozzi ◽  
B. Riosa ◽  
J.J. Piazze ◽  
L. Pollastrini ◽  
...  
Keyword(s):  
Bone Mass ◽  
Mass Density ◽  
Bone Mass Density ◽  
Menopausal Women ◽  
Post Menopausal

Bone mass density selectively correlates with serum markers of oxidative damage in post-menopausal women

2013 ◽  
Vol 51 (2) ◽  
Author(s):  
Carlo Cervellati ◽  
Gloria Bonaccorsi ◽  
Eleonora Cremonini ◽  
Carlo M. Bergamini ◽  
Alfredo Patella ◽  
...  
Keyword(s):  
Bone Mass ◽  
Oxidative Damage ◽  
Mass Density ◽  
Serum Markers ◽  
Bone Mass Density ◽  
Menopausal Women ◽  
Post Menopausal

scholarly journals The influence of bone quality on radiological outcome in 50 consecutive acetabular fractures treated with a pre-contoured anatomic suprapectineal plate

2021 ◽  
Author(s):  
Maximilian J. Hartel ◽  
Tareq Naji ◽  
Florian Fensky ◽  
Frank O. Henes ◽  
Darius M. Thiesen ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Bone Mass ◽  
Bone Quality ◽  
Hip Arthroplasty ◽  
Mass Density ◽  
Acetabular Fractures ◽  
Bone Mass Density ◽  
Radiological Outcome ◽  
Total Hip ◽  
The Impact

Abstract Purpose To investigate the range of indications of an anatomical-preshaped three-dimensional suprapectineal plate and to assess the impact of the bone mass density on radiologic outcomes in different types of acetabular fractures. Patients and methods A consecutive case series of 50 acetabular fractures (patient age 69 ± 23 years) treated with suprapectineal anatomic plates were analyzed in a retrospective study. The analysis included: Mechanism of injury, fracture pattern, surgical approach, need for additional total hip arthroplasty, intra- or postoperative complications, as well as bone mass density and radiological outcome on postoperative computed tomography. Results Most frequently, anterior column fracture patterns with and without hemitransverse components as well as associated two column fractures were encountered. The anterior intrapelvic approach (AIP) was used in 98% (49/50) of the cases as primary approach with additional utilization of the first window of the ilioinguinal approach in 13/50 cases (26%). Determination of bone density revealed impaired bone quality in 70% (31/44). Postoperative steps and gaps were significantly greater in this subgroup (p < 0.05). Fracture reduction quality for postoperative steps revealed anatomic results in 92% if the bone quality was normal and in 46% if impaired (p < 0.05). In seven cases (14%), the plate was utilized in combination with acute primary arthroplasty. Conclusion A preshaped suprapectineal plate provides good radiological outcomes in a variety of indications in a predominantly geriatric cohort. Impaired bone quality has a significantly higher risk of poor reduction results. In cases with extensive joint destruction, the combination with total hip arthroplasty was a valuable option.

A Pull-Out Resistant Pedicle Screw for the Osteoporotic Spine

2007 ◽  
Author(s):  
Karthik Ponnusamy ◽  
Sravisht Iyer ◽  
Alex Hui ◽  
Gaurav Gupta ◽  
Kartik Trehan ◽  
...  
Keyword(s):  
Bone Mass ◽  
Mass Density ◽  
Pedicle Screws ◽  
Bone Mass Density ◽  
Vertebral Compression Fractures ◽  
Osteoporotic Bone ◽  
Low Bone Mass ◽  
Compression Fractures ◽  
Pull Out ◽  
Increased Risk

Pedicle screws are commonly used in spine surgery to implant and affix metal devices to the spine. These screws are most commonly associated with cases that require rod or plate implantation. Use of pedicle screws in osteoporotic patients, however, is limited because they suffer from low bone mass density (BMD). The low BMD is harmful to patients in two ways — it leads to increased incidence of spinal trauma and also prevents surgeons from instrumenting osteoporotic patients because screws do not achieve the required fixation in osteoporotic patients [1]. The risk of trauma is increased due to the brittle bone and vertebral compression fractures, resulting in spinal misalignment and increased risk of future trauma. Instrumenting these cases with rods or plates, however, is impossible because osteoporotic bone is not strong enough to “hold” pedicle screws in, i.e., prevent screws from pulling out [2, 3].

scholarly journals The Effects of Vitamin D Supplementation on Serum Levels of 25 (OH) D, Serum Calcium, and Bone Density in Adolescent: A Literature Review

2021 ◽  
Vol 5 (2) ◽  
pp. 180
Author(s):  
Nurnashriana Jufri ◽  
Nurmaladewi Nurmaladewi ◽  
Fifi Nirmala
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Literature Review ◽  
Bone Mass ◽  
Serum Calcium ◽  
Biochemical Parameters ◽  
Linear Growth ◽  
Mass Density ◽  
Vitamin D Supplementation ◽  
Bone Mass Density

Latar Belakang: Stunting dan penurunan densitas tulang merupakan salah satu masalah gizi yang umum diderita oleh remaja. Hal ini terjadi akibat kurangnya asupan zat gizi yang adekuat terutama vitamin D yang berfungsi untuk pertumbuhan tulang dan mineralisasi jaringan. Jumlah yang terbatas dari makanan dan faktor pigmentasi kulit menjadi penyebab terjadinya defisiensi vitamin D sehingga dibutuhkan upaya suplementasi untuk memenuhi kebutuhan tersebut.Tujuan: Untuk menganalisis efek suplementasi vitamin D terhadap pertumbuhan linier remaja.Metode: Penelusuran artikel pada tinjauan pustaka ini dilakukan menggunakan mesin pencarian melalui Medline, PubMed, EBSCO, ELSEVIER, Cambridge Core, dan WILEY. Artikel memuat teks penuh, berbahasa inggris dan tahun terbit mulai dari 2010 hingga 2020. Kata kunci pencarian yang dimasukkan adalah vitamin D supplementation, adolescent or teenagers, linear growth, dan Bone Mass Density (BMD).Hasil: Hasil skrining menemukan 12 artikel yang memenuhi kriteria inklusi dan diklasifikasikan berdasarkan luaran penelitian yaitu kadar serum 25(OH)D merupakan parameter biokimia yang merupakan luaran yang terdapat pada 10 artikel penelitian. Parameter biokimia serum kalsium sebanyak 6 artikel, densitas tulang sebanyak 8 artikel, dan tinggi badan 2 artikel.Kesimpulan: Suplementasi vitamin D yang diberikan pada remaja yang sehat maupun tidak sehat terbukti meningkatkan kadar serum 25(OH)D.Kata kunci: Suplementasi vitamin D, serum 25(OH)D, densitas massa tulang, pertumbuhan linier remaja. ABSTRACT Background: Stunting and decreased bone density are some of the common nutritional problems that remain by adolescents. This occurs due to lack of adequate nutrition, especially vitamin D which functions for bone growth and tissue mineralization. A limited amount of food and skin pigmentation factors cause vitamin D deficiency so supplementation efforts are needed to meet those needs.Objective: To analyze the effect of vitamin D supplementation on the linear growth of adolescents.Method: Searching for articles in this literature review was done using a search engine through Medline, PubMed, EBSCO, ELSEVIER, Cambridge Core, and WILEY. The article contains the full text, English language, and year of publication from 2010 to 2020. The search keywords entered are vitamin D supplementation, adolescent or teenagers, linear growth, and Bone Mass Density (BMD).Results: The screening results found 12 articles that met the inclusion criteria and were classified based on research outcomes, namely serum 25 (OH) D levels were biochemical parameters which were the results contained in 10 research articles. Biochemical parameters of serum calcium were 6 articles, bone density were 8 articles, and height were 2 articles.Conclusion: Vitamin D supplementation given to healthy and unhealthy adolescents has been shown to increase serum 25 (OH) D levels.Keywords: Vitamin D supplementation, serum 25 (OH) D, bone mass density, adolescent linear growth. 

scholarly journals Pengaruh Latihan Resisten terhadap Kepadatan Tulang

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Audy K. Bella ◽  
Hedison Polii ◽  
Herlina I. S. Wungow
Keyword(s):  
Resistance Training ◽  
Bone Density ◽  
Literature Review ◽  
Bone Mass ◽  
Resistance Exercise ◽  
Mass Density ◽  
Anaerobic Exercise ◽  
Google Scholar ◽  
Bone Mass Density ◽  
Mineral Density

Abstract : Resistance or resistance training has been recommended as a widely used treatment strategy for dealing with bone loss. Types of exercise that can be done include walking, running, weights bearing, and swimming. According to WHO in 2018, more than 80% of the adult population worldwide has less physical activity. Studies show that resistant exercise can increase bone density. This literature review aims to determine the effect of resistance training on bone density. This study was in the form of a literature review with data searches using four databases, which are ClinicalKey, Pubmed, MedLine, and Google Scholar. Resistance exercise can increase bone density. There are two types of exercise, named aerobic and anaerobic exercises. Research has shown that anaerobic exercise is more effective in increasing bone mass density compared to aerobic exercise because anaerobic exercise provides a bigger mechanical load to the bones, which triggers the bones to regenerate. The conclusion is that resistance exercise can increase bone density.Keywords : Resistance exercise, bone density.  Abstrak : Latihan tahanan atau resisten telah direkomendasikan sebagai strategi pengobatan yang banyak digunakan untuk menghadapi hilangnya massa tulang. Jenis latihan yang bisa dilakukan antara lain jalan kaki, berlari, angkat beban, dan berenang. Menurut WHO pada tahun 2018, lebih dari 80% populasi orang dewasa di seluruh dunia memiliki aktivitas fisik yang kurang. Penelitian-penelitian membuktikan bahwa latihan resisten dapat meningkatkan kepadatan tulang. Tinjauan pustaka ini bertujuan untuk mengetahui pengaruh latihan resisten terhadap kepadatan tulang. Penelitian ini berbentuk literature review dengan pencarian data menggunakan empat database yaitu ClinicalKey, Pubmed, MedLine, dan Google Scholar. Kata kunci yang digunakan yaitu physical exercise ATAU resistance exercise ATAU resistance training ATAU effect of resistance exercise ATAU latihan tahanan ATAU latihan beban DAN bone mass ATAU bone mineral density. Latihan secara resisten dapat meningkatkan kepadatan tulang. Latihan dapat dilakukan dengan dua jenis, yaitu latihan aerobik dan anaerobik. Penelitian membuktikan bahwa latihan anaerobik lebih efektif dalam menungkatkan kepadatan massa tulang dibandingkan dengan latihan aerobik karena latihan anaerobik memberikan beban mekanik yang lebih besar untuk tulang sehingga memicu tulang untuk melakukan regenerasi.  Kesimpulannya adalah latihan resisten dapat meningkatkan kepadatan tulang.Kata Kunci : Latihan resisten, kepadatan tulang

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