Spike detection for calcium activity
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Set Up
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Abstract We present in this paper a global methodology for the spike detection in a biological context of fluorescence recording of GnRH-neurons calcium activity. For this purpose we first propose a simple stochastic model that could mimic experimental time series by considering an autoregressive AR(1) process with a linear trend and specific innovations involving spiking times. Estimators of parameters with asymptotic normality are established and used to set up a statistical test on estimated innovations in order to detect spikes. We compare several procedures and illustrate on biological data the performance of our procedure.
2018 ◽
Vol 22
(1)
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pp. 19-27
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1983 ◽
Vol 74
(S1)
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pp. S43-S43
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1995 ◽
Vol 202
(2-3)
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pp. 183-190
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2012 ◽
Vol 19
(6)
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pp. 675-683
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2019 ◽