Glucose absorption in the intestine of albino rats

2016 ◽  
Vol 0 (0) ◽  
Author(s):  
Olalubi A. Oluwasogo ◽  
Owoyele B. Victor ◽  
Ayinla M. Tayo ◽  
Akintunde J. Kehinde
Keyword(s):  
Small Intestine ◽  
Mammalian Species ◽  
External Environment ◽  
Glucose Absorption ◽  
Test Solution ◽  
Albino Rats ◽  
Rate Of Absorption

AbstractThe ability to absorb substances from the external environment is one of the features that make animals different from inanimate objects. In mammalian species, this quality is mainly the role of the small intestine. The process of absorption mainly takes place in the small intestine. This study was carried out to investigate the rate of glucose absorption in the intestine of albino rats and the effect of calcium and ouabain on the rate of glucose absorption.Albino rats weighing between 200 and 250 g were used for this experiment. Guts were isolated and cut to segments. Test solution was injected into each of the isolated segments, which were then assayed for glucose.The result revealed that the rate of glucose absorption in the intestine of albino rats were found to be 3.02×10Ouabain blocked the rate of absorption of glucose in the intestine of albino rats.

The effect of aldosterone on adiposity - The role of glucose absorption in the small intestine

2020 ◽  
Vol 531 (4) ◽  
pp. 628-635
Author(s):  
Hidekazu Shirai ◽  
Emiko Sato ◽  
Akiyo Sekimoto ◽  
Taeko Uchida ◽  
Yuji Oe ◽  
...  
Keyword(s):  
Small Intestine ◽  
Glucose Absorption

scholarly journals Effects of wheat-flour and oat mill fractions on jejunal flow, starch degradation and absorption of glucose over an isolated loop of jejunum in pigs

1994 ◽  
Vol 72 (2) ◽  
pp. 299-313 ◽  
Author(s):  
Helle N. Johansen ◽  
K. E. Bach Knudsen
Keyword(s):  
Small Intestine ◽  
Gastric Emptying ◽  
Wheat Flour ◽  
Starch Content ◽  
Mean Transit Time ◽  
Glucose Absorption ◽  
Major Influence ◽  
Starch Degradation ◽  
Proximal Small Intestine ◽  
Rate Of Absorption

The effect of cereal-based diets varying in dietary fibre (DF) on gastric emptying and glucose absorption over an isolated loop of jejunum was studied in four pigs fitted with two sets of re-entrant cannulas. The pigs were fed on either a wheat-flour diet or three diets based on oat flour (endosperm), rolled oats or oat bran containing different amounts of soluble DF. Mean transit time (MTT) of liquid estimated from the output from the first jejunal cannula was significantly higher with the two diets having the highest DF content, but MTT of dry matter (DM), starch, xylose and neutral non-starch polysaccharides (nNSP) was not correlated directly to the DF content of the diet. DF had a stimulatory effect on secretion of gastrointestinal juices, but the effect was not linearly correlated with the DF content of the diet. Starch was significantly degraded in digesta collected within 30 min after feeding with malto-oligosaccharides accounting for 140–147 g/kg total starch. The degradation was more extensive with higher DF and lower starch content of the diet. However, taking into account the differences in jejunal flow, the amount of malto-oligosaccharides available for absorption in the first 0.5 h decreased with higher levels of DF in the oat-based diets. The absorption of glucose from the isolated loop was 18–34 g/m intestine over an 8 h period with no significant differences between diets. This corresponded to a non-significant decrease in recovery of starch from 0.91 to 0.82 with increasing levels of DF and decreasing levels of starch in the diet. This suggests that the capacity for absorption of large doses of starch entering the proximal small intestine after ingestion of a carbohydrate-rich cereal-based diet has a major influence on the absorption at this site. Consequently any effect of DF on glucose absorption may be exerted either through the rate of gastric emptying or by impaired rate of absorption more distal in the small intestine and not by displacement of the site for starch absorption.

Intestinal absorption of glucose in rats after continuous challenge with larvae of Nippostrongylus brasiliensis

1984 ◽  
Vol 58 (3) ◽  
pp. 263-266 ◽  
Author(s):  
Kausar J. Cheema ◽  
A. M. Scofield
Keyword(s):  
Small Intestine ◽  
Glucose Absorption ◽  
Single Infection ◽  
Nippostrongylus Brasiliensis ◽  
Infection Level ◽  
Infective Larvae ◽  
Fluid Transfer ◽  
Repeated Infections

ABSTRACTThe rate of glucose absorption and metabolism and the associated fluid transfer of the small intestine of rats was measured in vitro using an everted sac technique after daily doses of 0, 5, 25 or 225 infective larvae of Nippostrongylus for periods of one to five weeks. Though there were occasional significant changes in the physiology of the intestine there were no obvious patterns or trends with respect to time at any infection level. This differs from the response after a single infection. The possible role of immune adaptation and reduced immunogenicity of the worms during repeated infections is considered.

scholarly journals Acute in vivo studies on glucose absorption from the small intestine of lambs, sheep and rats

1971 ◽  
Vol 25 (1) ◽  
pp. 57-76 ◽  
Author(s):  
R. G. White ◽  
V. J. Williams ◽  
R. J. H. Morris
Keyword(s):  
Body Weight ◽  
Small Intestine ◽  
Absorptive Capacity ◽  
Glucose Absorption ◽  
In Vivo Studies ◽  
Adult Sheep ◽  
Young Rats ◽  
Unit Body Weight ◽  
Rate Of Absorption

1. Rates of disappearance of glucose from ligated loops of small intestine in lambs, adult sheep and young rats were studied. The concentration of glucose in the lumen decreased exponentially with time, suggesting that within a range of concentrations of 166–277 m-moles/l glucose was absorbed mainly by passive diffusion.2. The rate of absorption of glucose from a 166 mM-solution based on either zero or first order kinetics and expressed as m-moles/m small intestine per h decreased along the intestine from the duodenum to the ileum in lambs and rats. The decrease was slight in adult sheep.3. The total absorptive capacity of the small intestine of adult grazing sheep for glucose from 166 mM-solutions (06 m-moles/kg body-weight per h) was approximately 25% of that for lambs less than 1 week of age.4. Young rats had a greater absorptive capacity of the small intestine (12.9m-moles/kg body-weight per h) than adult sheep of about 40 kg body-weight (0.6 m-moles/kg body-weight per h) and this largely reflected a longer small intestine per unit body-weight.5. The absorptive capacity of lambs for glucose was greater when the level of voluntary lactose intake was increased before an experiment. The absorptive capacity of the ileum of adult sheep given wheat was greater than that of grazing adult sheep.6. Developmental changes in glucose absorption are discussed in relation to normal changes in diet and to changes in the morphology of the small intestine with age.

Sign in / Sign up

Export Citation Format

Share Document