scholarly journals Total body fat, abdominal fat, body fat distribution and surrogate markers for health related to adipocyte fatty acid-binding protein (FABP4) in children

Author(s):  
Magnus Dencker ◽  
Anton Danielson ◽  
Magnus K. Karlsson ◽  
Per Wollmer ◽  
Lars B. Andersen ◽  
...  

AbstractBackground:The aim of the study was to assess possible relationships between adipocyte fatty acid-binding protein (FABP4) and total body fat (TBF), abdominal fat, body fat distribution, aerobic fitness, blood pressure, cardiac dimensions and the increase in body fat over 2 years in a community sample of children.Methods:A cross-sectional study was used in a community sample of 170 (92 boys and 78 girls) children aged 8–11 years. TBF and abdominal fat (AFM) were measured by dual-energy X-ray absorptiometry (DXA). TBF was also expressed as percentage of total body mass (BF%), and body fat distribution was calculated as AFM/TBF. Maximal oxygen uptake (VOResults:Partial correlations, with adjustment for sex, between FABP4 vs. ln TBF, ln BF%, ln AFM, AFM/TBF and VOConclusions:Findings from this community-based cohort of young children show that increased body fat and abdominal fat, more abdominal body fat distribution, low fitness, more LVM and increased LA, increased SBP and PP were all associated with increased levels of FABP4. Increase in TBF and abdominal fat over 2 years were also associated with increased levels of FABP4.

2018 ◽  
Vol 177 (3) ◽  
pp. 461-467 ◽  
Author(s):  
Magnus Dencker ◽  
Daniel Arvidsson ◽  
Magnus K. Karlsson ◽  
Per Wollmer ◽  
Lars B. Andersen ◽  
...  

1997 ◽  
Vol 21 (7) ◽  
pp. 536-541 ◽  
Author(s):  
H Shimizu ◽  
Y Shimomura ◽  
R Hayashi ◽  
K Ohtani ◽  
N Sato ◽  
...  

2001 ◽  
Vol 45 (2) ◽  
pp. 67-71 ◽  
Author(s):  
Lufiani Mulyadi ◽  
Clair Stevens ◽  
Sue Munro ◽  
Jennifer Lingard ◽  
Margaret Bermingham

2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 874
Author(s):  
Karlie J. Friesen ◽  
Katherine B. Gunter ◽  
Ralph Rozenek ◽  
Karen S. Clippinger

2014 ◽  
Vol 112 (4) ◽  
pp. 590-599 ◽  
Author(s):  
Jaya A. George ◽  
Shane A. Norris ◽  
Hendrick E. van Deventer ◽  
John M. Pettifor ◽  
Nigel J. Crowther

Vitamin D deficiency has been implicated in the aetiology of infectious diseases and metabolic syndrome. These diseases are prevalent in the African and Asian-Indian populations of South Africa; however, there is limited data on 25-hydroxyvitamin D (25(OH)D) concentrations in these populations. The aim of the present study was to assess the vitamin D status and its predictors in healthy adults in Johannesburg. We assessed the vitamin D status of 730 adult African and Asian-Indian subjects residing in Johannesburg. The contributions of sun exposure, season, dietary intake of Ca and vitamin D, total body fat and body fat distribution to 25(OH)D concentrations were assessed. The concentrations of 25(OH)D were measured by HPLC. The contribution of 25(OH)D3 to total 25(OH)D concentrations was assessed. The mean age of the subjects was 42·6 (sd 13·1) years (range: 18–65). Concentrations of 25(OH)D < 30 nmol/l were found in 28·6 % of the Asian-Indian subjects in comparison with 5·1 % of the African subjects (P< 0·0001). Parathyroid hormone (PTH) concentrations were negatively associated with 25(OH)D concentrations, while season and sun exposure were positive predictors explaining 16 % of the variance in 25(OH)D concentrations (P< 0·0001) in the African subjects. In the Asian-Indian subjects, PTH concentrations were negatively associated with 25(OH)D concentrations, while male sex, season and Ca supplementation were positive predictors and explained 17 % of the variance in 25(OH)D concentrations (P< 0·0001). In the multivariate regression analysis, neither total body fat nor body fat distribution was predictive of 25(OH)D concentrations in either group. In conclusion, factors such as sun exposure, dietary supplement use and ethnicity are important determinants of plasma 25(OH)D concentrations.


2011 ◽  
Vol 6 (2-2) ◽  
pp. e597-e602 ◽  
Author(s):  
Magnus Dencker ◽  
Per Wollmer ◽  
Magnus K. Karlsson ◽  
Christian Lindén ◽  
Lars B. Andersen ◽  
...  

2021 ◽  
pp. 37-56
Author(s):  
Nasrin Goolam Mahyoodeen ◽  
Nigel J. Crowther

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