scholarly journals Association between blood lipid levels and carotid intima-media thickness in Shanghai urban population

2013 ◽  
Vol 1 (1) ◽  
pp. 36-39
Author(s):  
Ya-Ya Guan ◽  
Mian Li ◽  
Xiao-Ou Chen ◽  
Wei Yang ◽  
Ming-Ming Tang ◽  
...  

Abstract Objective: The objective of the following study is to investigate the relationship between blood lipid levels and carotid intima-media thickness (CIMT) in Shanghai urban population. Materials and Methods: A total of 2504 residents over 40 years old in Jiading District of Shanghai municipality were divided into two groups in terms of the CIMT value 0.7 mm: Thickened group (n = 478) and normal group (n = 2026). All the patients received examinations of height, weight, waist, blood pressure, blood lipid level, hepatic and renal function, oral glucose tolerance test and carotid artery B-ultrasonography. Results: In comparison with those in CIMT normal group, the proportion of males, ages, body mass index, systolic blood pressure and levels of fast blood glucose, total cholesterol (TC), triglyceride (TG) and lowdensity lipoprotein cholesterol (LDL-C) were increased, but the levels of fast insulin were decreased (all P < 0.05). The risks of CIMT thickness were elevated by 19% and 25% as every increase in the standard deviation of the TC and LDL-C levels respectively (95% of confidence interval [CI] 1.08-1.31; 95% CI 1.13-1.37). Statistical analysis showed a significant correlation between CIMT thickness and TC/LDL-C. The levels of TG and high-density lipoprotein cholesterol were not associated with CIMT thickness. Conclusions: Levels of blood TC and LDL-C have significant correlations with the CIMT thickness in Shanghai urban population.

2021 ◽  
pp. postgradmedj-2021-141016
Author(s):  
Prasanna Herath ◽  
Savithri Wimalasekera ◽  
Thamara Amarasekara ◽  
Manoj Fernando ◽  
Sue Turale

Study purposeThe aim of this study was to determine the fractional exhaled nitric oxide (FeNO) levels, exhaled breath carbon monoxide (eCO) levels, blood pressure, blood lipid levels between smokers and non-smokers and to determine the association of smoking intensity with the above parameters.MethodsThis descriptive study was conducted in selected periurban areas of the Colombo District, Sri Lanka. Adult male current tobacco smokers (n=360), aged between 21 and 60 years were studied and compared with anthropometrically matched male non-smokers (n=180). Data were collected by interviewer-administered questionnaire, clinical assessment and measurement of FeNO by FENO monitor and eCO bySmokerlyser.ResultsSmokers had significantly lower mean FeNO levels and higher mean eCO values compared with non-smokers. Presentation of palpitations was higher among the smokers and a significantly positive correlation was identified between palpitations and eCO levels. There was a significantly positive correlation between the systolic blood pressure of smokers with the duration of smoking (DS), Brinkman Index (BI), Body Mass Index (BMI) and there was a significantly negative correlation with FeNO levels. The mean arterial pressure was positively correlated with the DS, BI and BMI. There was a significantly negative correlation between FeNO and the number of cigarettes smoked per day, DS and BI of smokers. Significantly higher total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), very LDL-C, TC: HDL ratio and low high density lipoprotein cholesterol (HDL-C) level was observed among smokers compared with the non-smokers.ConclusionsTobacco smoking was found to impact blood pressure and serum lipid levels thus enhancing the cardiovascular risk among smokers. The levels of eCO and FeNO are useful biomarkers for determining the intensity of smoking. The results indicate the necessity for urgent measures to stop cigarette smoking in Sri Lanka.


2018 ◽  
Vol 69 (6) ◽  
pp. 1550-1553
Author(s):  
Rosana Manea ◽  
Bianca Elena Popovici ◽  
Carmen Daniela Neculoiu ◽  
Dan Minea ◽  
Alina Calin

Hypertension is a major risk factor for progression of the atherosclerotic process and for developing of degenerative cardiovascular diseases in adulthood. The aim of this study is to evaluate how the measurement of carotid intima - media thickness for prediction of essential hypertension in children can be used.The study group included 81 children and the control group 61 children, all aged between 5 - 17 years and 11 months old, and admitted in Children Hospital Brasov in the period of 2009 � 2014. The study protocol included: BMI, blood pressure and Doppler echography of the common carotid artery for each group. Mean age of the patients from the study group was 13.67 years, 43.20 % girls and 56.80 % boys, while in the control group, the mean age was 14.07 years, 54.10% girls and 45.90 % boys. 70.37% of the children from the study group presented obesity, while in the control group 40.98% were obese. The IMTC study group ranged from 0.52 - 0.69 mm and the limits of the normotensive subjects were 0.32 -0.54 mm. In both groups the obese patients were found to have increased carotid artery intima-media, which means that IMTC was positively correlated with BMI (p=0.000001).It is necessary to identify diagnostic methods easily applicable for children, allowing involvement of the characteristics of the arterial wall in the degenerative pathological processes. Increased intima-media ratio is positively correlated with high values of blood pressure.


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