scholarly journals Ultrafast laser manufacturing of nanofluidic systems

Nanophotonics ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Felix Sima ◽  
Koji Sugioka
Keyword(s):  
Fluid Dynamics ◽  
Three Dimensional ◽  
Microfluidic System ◽  
Ultrafast Laser ◽  
Cancer Cell Migration ◽  
Extracellular Milieu ◽  
Promising Tool ◽  
Molecular Events ◽  
Laser Manufacturing ◽  
Chemical Fields

Abstract In the last decades, research and development of microfluidics have made extraordinary progress, since they have revolutionized the biological and chemical fields as a backbone of lab-on-a-chip systems. Further advancement pushes to miniaturize the architectures to nanoscale in terms of both the sizes and the fluid dynamics for some specific applications including investigation of biological sub-cellular aspects and chemical analysis with much improved detection limits. In particular, nano-scale channels offer new opportunities for tests at single cell or even molecular levels. Thus, nanofluidics, which is a microfluidic system involving channels with nanometer dimensions typically smaller than several hundred nm, has been proposed as an ideal platform for investigating fundamental molecular events at the cell-extracellular milieu interface, biological sensing, and more recently for studying cancer cell migration in a space much narrower than the cell size. In addition, nanofluidics can be used for sample manipulation in analytical chemistry, such as sample injections, separation, purifications or for quantitative and qualitative determinations. Among the nanofabrication technologies, ultrafast laser manufacturing is a promising tool for fabrication of nanofluidics due to its flexibility, versatility, high fabrication resolution and three dimensional (3D) fabrication capability. In this paper, we review the technological advancements of nanofluidic systems, with emphasis on fabrication methods, in particular ultrafast laser manufacturing. We present the challenges for issues concerning channel sizes and fluid dynamics, and introduce the applications in physics, biology, chemistry and engineering with future prospects.

scholarly journals Combining Virtual Reality and Organizational Neuroscience for Leadership Assessment

2021 ◽  
Vol 11 (13) ◽  
pp. 5956
Author(s):  
Elena Parra ◽  
Irene Alice Chicchi Giglioli ◽  
Jestine Philip ◽  
Lucia Amalia Carrasco-Ribelles ◽  
Javier Marín-Morales ◽  
...  
Keyword(s):  
Machine Learning ◽  
Eye Tracking ◽  
Ecological Validity ◽  
Objective Assessment ◽  
Leadership Skills ◽  
Three Dimensional ◽  
Machine Learning Techniques ◽  
Future Research ◽  
Promising Tool ◽  
Future Research Agenda

In this article, we introduce three-dimensional Serious Games (3DSGs) under an evidence-centered design (ECD) framework and use an organizational neuroscience-based eye-tracking measure to capture implicit behavioral signals associated with leadership skills. While ECD is a well-established framework used in the design and development of assessments, it has rarely been utilized in organizational research. The study proposes a novel 3DSG combined with organizational neuroscience methods as a promising tool to assess and recognize leadership-related behavioral patterns that manifest during complex and realistic social situations. We offer a research protocol for assessing task- and relationship-oriented leadership skills that uses ECD, eye-tracking measures, and machine learning. Seamlessly embedding biological measures into 3DSGs enables objective assessment methods that are based on machine learning techniques to achieve high ecological validity. We conclude by describing a future research agenda for the combined use of 3DSGs and organizational neuroscience methods for leadership and human resources.

Islet-on-a-chip: Biomimetic micropillar-based microfluidic system for three-dimensional pancreatic islet cell culture

2021 ◽  
Vol 183 ◽  
pp. 113215
Author(s):  
Patrycja Sokolowska ◽  
Kamil Zukowski ◽  
Justyna Janikiewicz ◽  
Elzbieta Jastrzebska ◽  
Agnieszka Dobrzyn ◽  
...  
Keyword(s):  
Cell Culture ◽  
Pancreatic Islet ◽  
Islet Cell ◽  
Three Dimensional ◽  
Microfluidic System ◽  
Pancreatic Islet Cell ◽  
Islet Cell Culture

scholarly journals Microfluidics for the rapid and controlled preparation of organic nanotubes of bent-core based dendrimers

2021 ◽  
Author(s):  
M. Blanca Ros ◽  
Martín Castillo-Vallés ◽  
Pilar Romero ◽  
Victor Sebastian
Keyword(s):  
Building Blocks ◽  
Microfluidic System ◽  
Promising Tool ◽  
Organic Nanotubes ◽  
Controlled Preparation

Recently, bent-core molecules have arised as excellent building blocks for the obtaining of nanostructures in solvents. Herein, we report the use of a coaxial microfluidic system as a promising tool...

The Effect of Bench Arrangements on the Natural Ventilation of a Multispan Greenhouse

2013 ◽  
Author(s):  
Sunita Kruger ◽  
Leon Pretorius
Keyword(s):  
Fluid Dynamics ◽  
Natural Ventilation ◽  
Three Dimensional ◽  
Two Dimensional ◽  
Low Velocity ◽  
Lower Velocity ◽  
Cfd Models ◽  
Temperature Distributions ◽  
Computational Fluid Dynamics Cfd ◽  
Plant Level

In this paper, the influence of various bench arrangements on the microclimate inside a two-span greenhouse is numerically investigated using three-dimensional Computational Fluid Dynamics (CFD) models. Longitudinal and peninsular arrangements are investigated for both leeward and windward opened roof ventilators. The velocity and temperature distributions at plant level (1m) were of particular interest. The research in this paper is an extension of two-dimensional work conducted previously [1]. Results indicate that bench layouts inside the greenhouse have a significant effect on the microclimate at plant level. It was found that vent opening direction (leeward or windward) influences the velocity and temperature distributions at plant level noticeably. Results also indicated that in general, the leeward facing greenhouses containing either type of bench arrangement exhibit a lower velocity distribution at plant level compared to windward facing greenhouses. The latter type of greenhouses has regions with relatively high velocities at plant level which could cause some concern. The scalar plots indicate that more stagnant areas of low velocity appear for the leeward facing greenhouses. The windward facing greenhouses also display more heterogeneity at plant level as far as temperature is concerned.

scholarly journals Computational Analysis to Factor Wind into the Design of an Architectural Environment

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Hassam Nasarullah Chaudhry ◽  
John Kaiser Calautit ◽  
Ben Richard Hughes
Keyword(s):  
Fluid Dynamics ◽  
Power Generation ◽  
Computational Fluid Dynamics ◽  
Three Dimensional ◽  
Numerical Data ◽  
Navier Stokes ◽  
Windward Side ◽  
Average Value ◽  
Continuity Equations ◽  
Prevailing Wind Direction

The effect of wind distribution on the architectural domain of the Bahrain Trade Centre was numerically analysed using computational fluid dynamics (CFD). Using the numerical data, the power generation potential of the building-integrated wind turbines was determined in response to the prevailing wind direction. The three-dimensional Reynolds-averaged Navier-Stokes (RANS) equations along with the momentum and continuity equations were solved for obtaining the velocity and pressure field. Simulating a reference wind speed of 6 m/s, the findings from the study quantified an estimate power generation of 6.4 kW indicating a capacity factor of 2.9% for the benchmark model. At the windward side of the building, it was observed that the layers of turbulence intensified in inverse proportion to the height of the building with an average value of 0.45 J/kg. The air velocity was found to gradually increase in direct proportion to the elevation with the turbine located at higher altitude receiving maximum exposure to incoming wind. This work highlighted the potential of using advanced computational fluid dynamics in order to factor wind into the design of any architectural environment.

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