Increased Levels of Lipid Oxidation Products in Rheumatically Destructed Bones o f Patients Suffering from Rheumatoid Arthritis

1998 ◽  
Vol 53 (11-12) ◽  
pp. 1061-1071 ◽  
Author(s):  
Wolfgang Jira ◽  
Gerhard Spiteller ◽  
Andreas Richter

Abstract The new indicator for lipid peroxidation (LPO) processes -9-hydroxy-10,12-octadecadie-noic acid (9-HODE) -was used to investigate, whether LPO processes are increased in destructed bone material of patients suffering from rheum atoid arthritis (RA) in comparison to surrounded non destructed bone material. The HODE content in destructed bones ex­ceeded that of non destructed ones of the same patient for a factor of about 3. In addition similar increases in leukotoxines and epoxy oleic acid in the destructed bone material were observed, indicating an increase of LPO processes in affected bone parts of pa­tients.

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
E. D. Wannaz ◽  
J. H. Rodriguez ◽  
T. Wolfsberger ◽  
H. A. Carreras ◽  
M. L. Pignata ◽  
...  

A pollution gradient was observed in tree foliage sampled in the vicinity of a large aluminium production facility in Patagonia (Argentina). Leaves ofEucalyptus rostrata, and Populus hybridusand different needle ages ofPinusspec. were collected and concentrations of aluminium (Al) and sulphur (S) as well as physiological parameters (chlorophyll and lipid oxidation products) were analyzed. Al and S concentrations indicate a steep pollution gradient in the study showing a relationship with the physiological parameters in particular membrane lipid oxidation products. The present study confirms that aluminium smelting results in high Al and sulphur deposition in the study area, and therefore further studies should be carried out taking into account potentially adverse effects of these compounds on human and ecosystem health.


1996 ◽  
Vol 44 (4) ◽  
pp. 1091-1095 ◽  
Author(s):  
Terri D. Boylston ◽  
Sarah A. Morgan ◽  
Kristen A. Johnson ◽  
Ray W. Wright, ◽  
Jan R. Busboom ◽  
...  

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