scholarly journals Maximal Heart Rate Prediction in Adults that Are Overweight or Obese

2011 ◽  
Vol 25 (5) ◽  
pp. 1407-1412 ◽  
Author(s):  
Shawn C Franckowiak ◽  
Devon A Dobrosielski ◽  
Suzanne M Reilley ◽  
Jeremy D Walston ◽  
Ross E Andersen
2015 ◽  
Vol 47 ◽  
pp. 123
Author(s):  
Danielle Ludlam ◽  
Stacey Beam ◽  
Sarah Henry ◽  
Michael Iwaskewcz ◽  
Erica Aikens ◽  
...  

2013 ◽  
Vol 31 (2) ◽  
pp. 11-16 ◽  
Author(s):  
Jacqueline S. Drouin ◽  
Lisa Birkmeier ◽  
Kristy Jones ◽  
Shanna Miller ◽  
Ronald Gellish ◽  
...  

2018 ◽  
Vol 38 (2) ◽  
pp. 111-117
Author(s):  
Elizabeth Godlasky ◽  
Trisha Hoffman ◽  
Sonya Weber-Peters ◽  
Richard Bradford ◽  
Nathan Miller ◽  
...  

1998 ◽  
Vol 30 (Supplement) ◽  
pp. 13
Author(s):  
A. T. M??ntt??ri ◽  
R. M.T. Laukkanen ◽  
P. Oja

2010 ◽  
Vol 28 (1) ◽  
pp. 32-33
Author(s):  
Jacqueline S. Drouin ◽  
Shanna L. Miller ◽  
Kristy Jones ◽  
Lisa Meloche ◽  
Ron Gellish

2019 ◽  
Vol 27 (5) ◽  
pp. 526-535 ◽  
Author(s):  
Pietro Laforgia ◽  
Francesco Bandera ◽  
Eleonora Alfonzetti ◽  
Marco Guazzi

Background Chronotropic insufficiency (CI) is defined as the inability of the heart to increase its rate commensurate with increased demand. Exercise CI is an established predictor of major adverse cardiovascular events in patients with cardiovascular diseases. Aim The aim of this study was to evaluate how exercise CI phenotypes different levels of cardiovascular risk and how it may better perform in defining cardiovascular risk when analysed in the context of cardiopulmonary exercise test (CPET)-derived measures and standard echocardiography in a healthy population with variable cardiovascular risk profile. Methods Apparently healthy individuals ( N = 702, 53.8% females) with at least one major cardiovascular risk factor (MCVRF; hypertension, diabetes, tabagism, dyslipidaemia, body mass index > 25), enrolled in the Euro-EX prevention trial, underwent CPET. CI was defined as the inability to reach 80% of the chronotropic index, that is, the ratio of peak heart rate – rest heart rate/peak heart rate – age predicted maximal heart rate (AMPHR: 220 – age), they were divided into four groups according to the heart rate reserve (<80%>) and respiratory gas exchange ratio (RER; < 1.05>) as a marker of achieved maximal performance. Subjects with a RER < 1.05 ( n = 103) were excluded and the final population ( n = 599) was divided into CI group ( n = 472) and no-CI group ( n = 177). Results Compared with no-CI, CI subjects were more frequently females with a history of hypertension in a high rate. CI subjects also exhibited a significantly lower peak oxygen uptake (VO2) and circulatory power and an echocardiographic pattern indicative of higher left atrial volume index and left ventricular mass index. An inverse stepwise relationship between heart rate reserve and number of MCVRFs was observed (one MCVRF: 0.71 ± 0.23; two MCVRFs: 0.68 ± 0.24, three MCVRFs: 0.64 ± 0.20; four MCVRFs: 0.64 ± 0.23; five MCVRFs: 0.57 ± 18; p < 0.01). In multivariate analysis the only variable found predicting CI was peak VO2 ( p < 0.05; odds ratio 0.91; confidence interval 0.85–0.97). Conclusions In a population of apparently healthy subjects, exercise CI is common and phenotypes the progressive level of cardiovascular risk by a tight relationship with MCVRFs. CI patients exhibit some peculiar abnormal exercise gas exchange patterns (lower peak VO2 and exercise oscillatory ventilation) and echo-derived measures (higher left atrium size and left ventricle mass) that may well anticipate evolution toward heart failure.


2016 ◽  
Vol 118 (11) ◽  
pp. 1751-1757 ◽  
Author(s):  
Rupert K. Hung ◽  
Mouaz H. Al-Mallah ◽  
Seamus P. Whelton ◽  
Erin D. Michos ◽  
Roger S. Blumenthal ◽  
...  

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Vivek K Prasad ◽  
Gregory A Hand ◽  
Mei Sui ◽  
Duck C Lee ◽  
Deepika Shrestha ◽  
...  

Abstract Objectives— We examined the association between heart rate reserve (HRR) and incident hypertension in men in the Aerobics Center Longitudinal Study. Research design and Methods— A total of 10418 healthy normotensive men, who did not have an abnormal electrocardiogram or a history of heart attack, stroke, cancer, or diabetes, performed a maximal treadmill exercise test and were followed for the incidence of hypertension. HRR was defined as the difference between maximal heart rate during exercise test and resting heart rate. Results— During a mean follow-up of 6 years, there were 2831 cases of incident hypertension. Compared with men in the reference category (the lowest quartile of HRR), the risk of incident hypertension was significantly lower in the highest quartile of HRR with a hazard ratio 0.67 (95% CI: 0.60-0.75) when adjusted for age and baseline examination year. Further adjustment for smoking, heavy drinking, body mass index (BMI), resting systolic and diastolic blood pressure, cholesterol, blood glucose and cardio respiratory fitness, resulted a hazard ratio of 0.84 (95% CI:0.74-0.95). This result was almost similar when we stratified them into younger and older men with hazard ratio of 0.77(95% CI: 0.62-0.98) and 0.78 (95% CI: 0.66-0.90) respectively. We also found a significant lower hypertension risk associated with higher HRR among high risk groups such as overweight, low fitness, or prehypertension with hazard ratio of 0.82(95% CI:0.70-0.97), 0.80(95% CI:0.67-0.96), 0.76(95% CI:0.64-0.88) respectively. Conclusion— Risk of Incident hypertension was significantly lower in men with higher HRR. High HRR was also associated with lower risk of developing hypertension irrespective of age and status of risk factors such as high BMI, low fitness and prehypertension. Therefore, HRR may be considered as a reliable exercise parameter for predicting the risk of incident hypertension.


Author(s):  
В.А. Шумков ◽  
К.А. Загородникова ◽  
С. А. Болдуева ◽  
А.А. Мурзина ◽  
В.Б. Петрова

Проанализировано влияние генетических вариантов CYP2D6*3 (2549delA) и CYP2D6*4 (1846G>A), а также других факторов на фармакодинамику бисопролола у пациентов с острым коронарным синдромом. В исследование были включены 97 пациентов, поступивших в клинику кардиологии с диагнозом острого коронарного синдрома, - 60 мужчин и 37 женщин, средний возраст - 63±10 лет. Выявлена взаимосвязь носительства аллельного варианта CYP2D6*4 (1846G>A) и максимальной ЧСС при нагрузке (R-0,21; р<0,05). При оценке влияния прочих факторов обнаружено, что основным предиктором максимальной ЧСС при нагрузке является возраст пациентов (β=-0,6; SE=0,07; p<0,001), при этом носительство CYP2D6*4 чаще встречается у лиц, переносящих острый коронарный синдром в более старшем возрасте (r=0,2; p<0,05). We have analyzed influence of genetic variants CYP2D6*3 (2549delA) and CYP2D6*4 (1846G>A), as well as other factors on effects of bisoprolol in patients with acute coronary syndrome. The study included 97 patients with acute coronary syndrome. Mean age was 63±10 years; 60 men and 37 women. We have found association between carriage of CYP2D6*4 (1846G>A) and maximal heart rate at exertion (R-0,21; р<0,05). When the correction for potential confounders was made, age was the only significant predictor of maximal heart rate (β=-0,6; SE=0,07; p<0,001). At the same time it was found that CYP2D6*4 was associated with more advanced age of the patients (r=0,2; p<0,05).


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