Drinking patterns among individuals with and without DSM-IV alcohol use disorders.

2000 ◽  
Vol 61 (1) ◽  
pp. 111-120 ◽  
Author(s):  
D A Dawson
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorders ◽  
Drinking Patterns ◽  
Dsm Iv

scholarly journals A Cross-Sectional Comparison of Drinking Patterns, Alcohol Use and Related Medical Morbidities in a Secondary Versus Tertiary Setting

2015 ◽  
Vol 11 (2) ◽  
pp. 152-157
Author(s):  
A Risal ◽  
H Tharoor
Keyword(s):  
Alcohol Use ◽  
Alcohol Dependence ◽  
Tertiary Care ◽  
Alcohol Use Disorders ◽  
Care Utilization ◽  
Drinking Patterns ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Patterns Of Drinking ◽  
Level Hospital

Background Alcohol Dependence exists in different spectrums at different settings and associated with various medical morbidities, disability and health care utilization costs. Objectives To study the drinking patterns, alcohol use disorders and alcohol related medical morbidities in patients diagnosed with Alcohol Dependence Syndrome (ADS) and attending out / in-patient psychiatry services at secondary and tertiary care centre. Methods A cross-sectional comparative study was done among the patients diagnosed with ADS attending psychiatry services at District hospital, Udupi and Kasturba Hospital, Manipal. Serial sampling was done. Patients having any other psychiatric illnesses were excluded. The two groups were compared in relation to socio-demographic variables, drinking related variables, patterns of drinking and alcohol related medical morbidities identified. Results Significant differences in some socio-demographic parameters among the patients from the two different treatment centers were found with secondary level hospital (N=50) having more illiterate, laborers and below the poverty line population in comparison to the tertiary level hospital (N=75). Maximum frequency of gastro-intestinal morbidities was seen in both the hospital population, irrespective of the patterns of drinking. Conclusion Alcohol use disorders and alcohol related medical morbidities show some variations in their presentations in the different treatment centers. DOI: http://dx.doi.org/10.3126/kumj.v11i2.12492 Kathmandu University Medical Journal Vol.11(2) 2013: 152-157

scholarly journals The role of mental disorders in the risk and speed of transition to alcohol use disorders among community youth

2010 ◽  
Vol 41 (5) ◽  
pp. 1073-1085 ◽  
Author(s):  
S. Behrendt ◽  
K. Beesdo-Baum ◽  
P. Zimmermann ◽  
M. Höfler ◽  
A. Perkonigg ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Mental Disorders ◽  
Social Phobia ◽  
Age Of Onset ◽  
Alcohol Use Disorders ◽  
Externalizing Disorders ◽  
Increased Risk ◽  
Rapid Transition ◽  
Dsm Iv

BackgroundAmong adolescents and young adults with DSM-IV alcohol use disorders (AUDs), there are inter-individual differences in the speed of transition from initial alcohol use (AU) to AUD. AUDs are highly co-morbid with other mental disorders. The factors associated with rapid transition from first AU to AUD remain unknown and the role of mental disorders in rapid transitions is unclear. Given this background we examined (1) whether prior anxiety, mood, externalizing and non-alcohol substance use disorders are related to the risk and speed of transition from first AU to DSM-IV alcohol abuse (AA) and alcohol dependence (AD) and (2) whether early age of onset of prior mental disorders (PMDs) is a promoter of rapid transition.MethodA total of 3021 community subjects (97.7% lifetime AU) aged 14–24 years at baseline were followed up prospectively for up to 10 years. AU and mental disorders were assessed with the DSM-IV/M-CIDI.ResultsAmong subjects with lifetime AU, several PMDs, such as specific phobia, bipolar disorder and nicotine dependence, were associated with an increased risk of AUD independent of externalizing disorders. Associations of PMDs with the speed of transition to AUDs were mostly weak and inconsistent. Only social phobia and externalizing disorders were associated with faster transitions to AD even after adjustment for other PMDs. Earlier age of onset of PMD was not associated with rapid transition.ConclusionsMental disorders are associated with the risk of AUD. With the possible exception of social phobia and externalizing disorders, they do not promote rapid transition, even if they occur particularly early. Future research needs to identify factors relevant to rapid transition to AUD.

scholarly journals Drinking Patterns and Alcohol Use Disorders in São Paulo, Brazil: The Role of Neighborhood Social Deprivation and Socioeconomic Status

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e108355 ◽  
Author(s):  
Camila Magalhães Silveira ◽  
Erica Rosanna Siu ◽  
James C. Anthony ◽  
Luis Paulo Saito ◽  
Arthur Guerra de Andrade ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Alcohol Use ◽  
Social Deprivation ◽  
Alcohol Use Disorders ◽  
Sao Paulo ◽  
São Paulo ◽  
Drinking Patterns

Antisocial Behavioral Syndromes and DSM-IV Alcohol Use Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

2007 ◽  
Vol 31 (5) ◽  
pp. 814-828 ◽  
Author(s):  
Risë B. Goldstein ◽  
Deborah A. Dawson ◽  
Tulshi D. Saha ◽  
W. June Ruan ◽  
Wilson M. Compton ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorders ◽  
Behavioral Syndromes ◽  
Epidemiologic Survey ◽  
Dsm Iv

scholarly journals Transcriptional, epigenetic, and functional reprogramming of blood monocytes in non-human primates following chronic alcohol drinking

2021 ◽  
Author(s):  
Sloan A Lewis ◽  
Suhas Sureshchandra ◽  
Brianna Doratt ◽  
Vanessa Jimenez ◽  
Cara Stull ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Inflammatory Response ◽  
Alveolar Macrophages ◽  
Alcohol Use Disorders ◽  
Cytokine Signaling ◽  
Drinking Patterns ◽  
Blood Monocytes ◽  
Monocyte Subsets ◽  
Self Administration ◽  
Impaired Wound Healing

Chronic heavy drinking (CHD) of alcohol is a known risk factor for increased susceptibility to bacterial and viral infection as well as impaired wound healing. Evidence suggests that these defects are mediated by a dysregulated inflammatory response originating from myeloid cells, notably monocytes and macrophages, but the mechanisms remain poorly understood. Our ability to study CHD is impacted by the complexities of human drinking patterns and behavior as well as comorbidities and confounding risk factors for patients with alcohol use disorders. To overcome these challenges, we utilize a translational rhesus macaque model of voluntary ethanol self-administration that closely recapitulates human drinking patterns and chronicity. In this study, we examined the effects of CHD on blood monocytes and alveolar macrophages in control and CHD female macaques after 12 months of daily ethanol consumption. While monocytes from CHD female macaques generated a hyper-inflammatory response to ex vivo LPS stimulation, their response to E.Coli was dampened. In depth scRNA-Seq analysis of purified monocytes revealed significant shifts in classical monocyte subsets with accumulation of cells expressing markers of hypoxia (HIF1A) and inflammation (NFkB signaling pathway) in CHD macaques. The increased presence of monocyte subsets poised to generate a hyperinflammatory response was confirmed by the epigenetic analysis which revealed higher accessibility of promoter regions that regulate genes involved in cytokine signaling pathways. Finally, alveolar macrophages (AM) from the same animals produced higher levels of inflammatory mediators in response to LPS stimulation, but reduced ability to phagocytose bacteria. Collectively, data presented in this manuscript demonstrate that CHD primes monocytes and tissue-resident macrophages towards a more hyper-inflammatory immune response with compromised functional abilities, which could be used in diagnostic purposes or preventative measures for patients with alcohol use disorders.

Reclassifying DIS-III-R Alcohol Use Disorders to DSM-IV Criteria in a Sample of Convicted Impaired Drivers

2006 ◽  
Vol 67 (6) ◽  
pp. 898-903
Author(s):  
JANET C'DE BACA ◽  
GARNETT P. McMILLAN ◽  
SANDRA C. LAPHAM
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorders ◽  
Dsm Iv
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