PLASMA LEVELS OF TESTOSTERONE IN BULLS

1978 ◽  
Vol 88 (4) ◽  
pp. 787-792 ◽  
Author(s):  
Anne Sundby ◽  
P. A. Torjesen
Keyword(s):  
Testosterone Level ◽  
Plasma Levels ◽  
Leydig Cells ◽  
Sharp Decrease ◽  
Plasma Testosterone ◽  
Plasma Samples ◽  
Elevated Plasma ◽  
Plasma Testosterone Level ◽  
Testosterone Levels ◽  
Testosterone Production

ABSTRACT Administration of 6000 IU HCG to 4 bulls was followed by an elevation of plasma testosterone lasting for 9–13 days. When HCG administration was repeated, the testosterone response was shortened to 4–6 days in 3 bulls due to the formation of antibodies against HCG. The appearance of HCG antibodies coincided with a sharp decrease in the plasma testosterone level, indicating that Leydig cells have to be under continuous HCG stimulation to maintain increased testosterone production. No antibody against bovine LH was detected in the plasma samples containing antibodies against HCG. In one bull the response following the second HCG injection was similar to the plasma testosterone pattern following the first. No antibodies against HCG were found in this bull. Five bulls received 750 IU HCG twice. Following the period with elevated plasma testosterone levels, subnormal levels were observed after both injections. One injection led to decreased levels without development of antibodies against HCG while the second HCG injection led to subnormal testosterone levels concomitant with measurable antibodies against HCG.

THE EFFECT OF MESTEROLONE ADMINISTRATION TO NORMAL MEN ON THE PITUITARY-TESTICULAR FUNCTION

1974 ◽  
Vol 77 (2) ◽  
pp. 380-386 ◽  
Author(s):  
A. Aakvaag ◽  
S. B. Strømme
Keyword(s):  
Protein Binding ◽  
Testosterone Level ◽  
Plasma Levels ◽  
Mean Value ◽  
Plasma Testosterone ◽  
Testicular Function ◽  
Plasma Testosterone Level ◽  
Before And After ◽  
The Mean ◽  
Normal Men

ABSTRACT Mesterolone (1α-methyl-5α-dihydrotestosterone) has been given to 10 normal men, age 24–27 years, and the effect on the plasma levels of ICSH, FSH and testosterone has been studied. No effect on the plasma levels of ICSH and FSH could be detected. After 4 weeks on 75 mg mesterolone per day a significant (P < 0.01) drop in the mean value for plasma testosterone level was observed, 5.2 to 4.0 ng/ml. After another 4 weeks on 150 mg mesterolone per day a further decrease to 3.5 ng/ml was found. During mesterolone administration the protein binding of testosterone in plasma was significantly reduced, and it appeared that the level of free (non-protein bound) testosterone in diluted plasma remained unchanged, 0.37 and 0.41 ng/ml, before and after mesterolone administration respectively. The results suggest that mesterolone given in doses of 75 and 150 mg/day to normal men does not suppress the pituitary ICSH production or the testicular testosterone production.

Influence of adrenalectomy on maturation of gonadotrophin function in the male rat

1982 ◽  
Vol 95 (1) ◽  
pp. 1-NP ◽  
Author(s):  
G. Lescoat ◽  
D. Lescoat ◽  
D. H. Garnier
Keyword(s):  
Testosterone Level ◽  
Plasma Levels ◽  
Male Rat ◽  
Plasma Testosterone ◽  
Seminiferous Tubules ◽  
Plasma Testosterone Level ◽  
Hormonal Balance ◽  
Adrenalectomized Rats ◽  
Intact Rats

The effects were studied of adrenalectomy performed at 25 days of age on the maturation of LH function and the testes during puberty (i.e. 30–50 days of age) in the male rat. In intact rats the plasma LH level increased and then decreased and the plasma testosterone level increased progressively. In adrenalectomized rats the plasma levels of LH and testosterone did not vary significantly over the same period of time. Adrenalectomy decreased the plasma levels of LH and testosterone. The different perturbations in hormonal balance induced a decrease in the size of the seminiferous tubules and a delay in spermatogenesis.

THE EFFECT OF MAINTENANCE HAEMODIALYSIS AND RENAL TRANSPLANTATION ON THE PLASMA TESTOSTERONE LEVELS OF MALE PATIENTS IN CHRONIC RENAL FAILURE

1975 ◽  
Vol 80 (3) ◽  
pp. 577-582 ◽  
Author(s):  
J. Alaghband Zadeh ◽  
K. G. Koutsaimanis ◽  
A. P. Roberts ◽  
R. Curtis ◽  
J. R. Daly
Keyword(s):  
Renal Failure ◽  
Circadian Rhythm ◽  
Renal Transplantation ◽  
Chronic Renal Failure ◽  
Testosterone Level ◽  
Plasma Testosterone ◽  
Plasma Testosterone Level ◽  
Testosterone Levels ◽  
Maintenance Haemodialysis ◽  
Male Patients

ABSTRACT Plasma testosterone levels were measured at the beginning of a 14 h period of haemodialysis, one hour later, midway through the period and at the end, in 18 male patients in chronic renal failure. The level fell from 8.70 ± 2.63 nmol/l at the start to 8.08 ± 3.33 nmol/l at the midpoint, and rose again to 10.12 ± 3.9 nmol/l at the end of a dialysis. All seven of the patients tested on a non-dialysis day showed similar levels at the same time. At the beginning of a 10 h dialysis period 19 other male patients showed a plasma testosterone level of 10.12 ± 3.99 nmol/l and, at the end, of 8.98 ± 4.54 nmol/l. Over the same period the plasma corticosteroids rose from 301 ± 101 nmol/l to 483 ± 199 nmol/l. Eight male patients who had had successful renal transplantation had plasma testosterone levels of 15.08 ± 7.49 nmol/l. It is concluded that the plasma testosterone is low in chronic renal failure, but the circadian rhythm is preserved. Treatment with maintenance haemodialysis does not itself affect the plasma testosterone level, or alter the circadian rhythm despite the procedure's being a stress. Successful renal transplantation restores the plasma testosterone to normal in most cases.

scholarly journals Association of plasma total testosterone level and metabolic syndrome in adult males

2019 ◽  
Vol 9 (3) ◽  
pp. e27-e27
Author(s):  
Alireza Hejrati ◽  
Amir Ziaee ◽  
Mohammad Pourmahmudian ◽  
Elham Bayani ◽  
Mehrnaz Ghavamipour ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Testosterone Level ◽  
Density Lipoprotein ◽  
Serum Testosterone ◽  
Plasma Testosterone ◽  
Adult Males ◽  
Plasma Testosterone Level ◽  
Testosterone Levels ◽  
Low Testosterone ◽  
The Relationship

Introduction: Low testosterone level has strongly been correlated with body fat accumulation and abdominal obesity in men. Objectives: This study aimed to evaluate testosterone level in men with and without metabolic syndrome to determine the relationship between testosterone and metabolic syndrome. Patients and Methods: This case-control study was conducted on 172 cases of metabolic syndrome and 172 participants as a control group in Rasoul Akram hospital, Tehran, Iran. Demographic characteristics, fasting blood sugar (FBS), high-density lipoprotein (HDL), low-density lipoprotein (LDL), cholesterol, triglyceride (TG), and testosterone levels were recorded. SPSS version 21.0 and SAS version 9.1 were used for statistical analysis. Level of significance was considered 0.05. Results: The mean age of the two groups were 45.1±9.3 years and 41.5 ±11.2 years, respectively. There was a significant difference in serum testosterone levels between both groups and low testosterone levels were associated with metabolic syndrome (P<0.001). Serum testosterone levels showed a significant negative correlation with age in the metabolic syndrome group (r= -0.16, P=0.02). The relationship between metabolic syndrome and total plasma testosterone level using logistic regression model showed that, by increasing the total plasma testosterone level, the odds ratio for metabolic syndrome was 0.076 (95% CI: 0.027-0.216; P< 0.001). Conclusion: According to the results, low level of testosterone was related to the presence of metabolic syndrome in adult males. Future studies can investigate diagnostic value of testosterone level in this syndrome.

Infantile acne associated with a high plasma testosterone level in a 21-month-old boy

1995 ◽  
Vol 33 (4) ◽  
pp. 676-678 ◽  
Author(s):  
Nobuko Tabata ◽  
Tadashi Terui ◽  
Mariko Watanabe ◽  
Hachiro Tagami
Keyword(s):  
Testosterone Level ◽  
High Plasma ◽  
Plasma Testosterone ◽  
Plasma Testosterone Level

scholarly journals Using a Commercially Available Enzyme Immunoassay to Quantify Testosterone in Avian Plasma

The Condor ◽  
2007 ◽  
Vol 109 (1) ◽  
pp. 181-186 ◽  
Author(s):  
Brian E. Washburn ◽  
Joshua J. Millspaugh ◽  
Dana L. Morris ◽  
John H. Schulz ◽  
John Faaborg
Keyword(s):  
Enzyme Immunoassay ◽  
Small Volume ◽  
Plasma Testosterone ◽  
Plasma Samples ◽  
Zenaida Macroura ◽  
Vireo Olivaceus ◽  
Testosterone Levels ◽  
Passerina Cyanea ◽  
Assay Procedure ◽  
Mourning Doves

Abstract Abstract Using a commercially available testosterone enzyme immunoassay (EIA), we developed and validated an assay procedure for determining testosterone levels in small-volume (20 µL) avian plasma samples. We evaluated this EIA's utility by measuring plasma testosterone levels in Mourning Doves (Zenaida macroura), White-eyed Vireos (Vireo griseus), Red-eyed Vireos (Vireo olivaceus), and Indigo Buntings (Passerina cyanea). Standard biochemical validations (e.g., parallelism, recovery of exogenous testosterone) demonstrated that the assay accurately and precisely measured testosterone in avian plasma. We compared plasma testosterone levels in males and females of all four species and Indigo Buntings in various reproductive stages to physiologically validate the assay's ability to determine biologically important changes in testosterone levels. Plasma testosterone levels were higher in males compared to females in three of four species. Prebreeding and breeding male Indigo Buntings had higher circulating testosterone levels than postbreeding males. Testosterone levels in our study were similar to reported values for other passerine species using radioimmunoassay procedures. Our results suggest that this EIA procedure is very effective for determining testosterone levels in small-volume avian plasma samples and is sensitive enough to detect biologically important changes in the gonadal activity of birds. Thus, this assay has considerable utility for measuring testosterone in small birds (<15 g), from which only small volumes of plasma (20 µL) can be collected.

THE EFFECT OF CYPROTERONE ACETATE ON THE PLASMA GONADOTROPHIN RESPONSE TO GONADOTROPHIN RELEASING HORMONE

1976 ◽  
Vol 81 (3) ◽  
pp. 680-684 ◽  
Author(s):  
Richard A. Donald ◽  
Eric A. Espiner ◽  
R. John Cowles ◽  
Joy E. Fazackerley
Keyword(s):  
Testosterone Level ◽  
Cyproterone Acetate ◽  
Luteinising Hormone ◽  
Follicle Stimulating Hormone ◽  
Plasma Testosterone ◽  
Plasma Testosterone Level ◽  
Releasing Hormone ◽  
Lh Release ◽  
Gonadotrophin Releasing Hormone ◽  
Male Patients

ABSTRACT Cyproterone acetate (100–150 mg daily) was administered to 8 male patients with excessive libido. Within 3 months a significant fall (P < 0.02) in plasma testosterone was demonstrated. The plasma luteinising hormone (LH) and follicle stimulating hormone (FSH) responses to gonadotrophin releasing hormone (LH/FSH-RH) were also significantly impaired (P < 0.05). A direct correlation between the resting plasma testosterone level and the LH response to LH/FSH-RH was demonstrated (r = 0.743). It is concluded that the fall in plasma testosterone levels in patients receiving cyproterone acetate may be attributed to suppression of LH release, rather than an antiandrogen effect on the testis or hypothalamus.

PLASMA TESTOSTERONE AND SHELL QUALITY

1989 ◽  
Vol 69 (4) ◽  
pp. 1107-1109
Author(s):  
S. LEESON ◽  
C. D. BENNETT ◽  
L. J. CASTON ◽  
C. E. ANDERSON-LANGMUIR ◽  
R. J. ETCHES
Keyword(s):  
Key Words ◽  
Testosterone Level ◽  
Plasma Testosterone ◽  
Production Cycle ◽  
Testosterone Concentration ◽  
Shell Quality ◽  
Testosterone Levels ◽  
Commercial Strain ◽  
Eggshell Quality ◽  
Key Words Testosterone

Plasma testosterone levels were measured in commercial strain Leghorn pullets from 16 to 80 wk of age. Testosterone level was high just prior to first egg, but subsequently declined and stayed at a constant level through the production cycle. There was no relationship between testosterone concentration and eggshell quality (P > 0.05). Key words: Testosterone, shell quality

scholarly journals The Effect of Eurycoma longifolia on Sperm Quality of Male Rats

2009 ◽  
Vol 4 (10) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Kit-Lam Chan ◽  
Bin-Seng Low ◽  
Chin-Hoe Teh ◽  
Prashanta K. Das
Keyword(s):  
Testosterone Level ◽  
Sperm Quality ◽  
Sperm Count ◽  
Male Rats ◽  
Plasma Testosterone ◽  
Seminiferous Tubules ◽  
Albino Rats ◽  
Meoh Extract ◽  
Plasma Testosterone Level ◽  
Etoac Fraction

The present study investigated the effects of a standardized methanol extract of E. longifolia Jack containing the major quassinoid constituents of 13α(21)-epoxyeurycomanone (1), eurycomanone (2), 13α,21-dihydroeurycomanone (3) and eurycomanol (4) on the epididymal spermatozoa profile of normal and Andrographis paniculata induced infertile rats. The standardized MeOH extract at doses of 50, 100 and 200 mg/kg, the EtOAc fraction (70 mg/kg), and standardized MeOH extract at 200 mg/kg co-administered with the EtOAc fraction of A. paniculata at 70 mg/kg were each given orally to male Sprague-Dawley albino rats for 48 consecutive days. The spermatozoa count, morphology, motility, plasma testosterone level and Leydig cell count of the animals were statistically analyzed by ANOVA with a post-hoc Tukey HSD test. The results showed that the sperm count of rats given the standardized MeOH extract alone at doses of 50, 100 and 200 mg/kg were increased by 78.9, 94.3 and 99.2 %, respectively when compared with that of control (p < 0.01). The low count, poor motility and abnormal morphology of the spermatozoa induced by the A. paniculata fraction were significantly reversed by the standardized MeOH extract of E. longifolia (p < 0.001). The plasma testosterone level of the rats treated with the standardized MeOH extract at 200 mg/kg was significantly increased (p < 0.01) when compared with that of the control and infertile animals. The spermatocytes in the seminiferous tubules and the Leydig cells appeared normal. Testosterone level was significantly higher in the testes (p < 0.01) than in the plasma after 30 days of oral treatment with the standardized MeOH extract. Interestingly, eurycomanone (2) alone was detected in the rat testis homogenates by HPLC-UV and confirmed by LC/MS, and may have contributed towards the improvement of sperm quality. Thus, the plant may potentially be suitable for the management of male infertility.

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