scholarly journals The effect of treatment on quality of life in patients with acromegaly: a prospective study

2020 ◽  
Vol 182 (3) ◽  
pp. 319-331 ◽  
Author(s):  
T L C Wolters ◽  
S H P P Roerink ◽  
R B T M Sterenborg ◽  
M A E M Wagenmakers ◽  
O Husson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Disease Control ◽  
Negative Influence ◽  
First Year ◽  
Limited Information ◽  
Time Points ◽  
Treatment Naïve ◽  
Effect Of Treatment

Objective Acromegaly has a negative influence on health-related quality of life (HRQoL). Previous studies provide limited information on the course of HRQoL during treatment. This study aims to assess the effect of treatment on the course of HRQoL at six predefined time points. Design This prospective study examines HRQoL in treatment-naive patients before and during the first 2.5 years of acromegaly treatment. Methods Therapy-naive acromegaly patients completed three validated questionnaires (RAND-36, AcroQoL, and the Appearance Self-Esteem (ASE)) at six predetermined time points before, during, and after treatment. Outcomes were correlated to IGF1 levels and disease control status. Results Twenty-seven acromegaly patients completed the questionnaires at all time points. After treatment, all patients had controlled acromegaly. Scores of RAND-36 domains General health, Vitality and Health change, and all AcroQoL dimensions (except for Relations) improved during treatment (P ≤ 0.003); the largest changes were detected during the first year. Gender influenced HRQoL scores, since AcroQoL scores significantly improved in males but not in females. Over time, IGF1 levels were negatively correlated with HRQoL. After 2.5 years of follow-up, HRQoL of controlled patients was still lower than in the general population. Conclusion HRQoL of acromegaly patients was considerably reduced at diagnosis. Disease control was associated with an improvement of HRQoL scores. Males showed a more pronounced improvement than females. The largest changes were detected in the first year of treatment. However, HRQoL during and after treatment remained impaired in acromegaly patients, emphasizing the need of additional support.

A prospective study on living related kidney donors’ quality of life in the first year: choosing appropriate reference data

2012 ◽  
Vol 26 (4) ◽  
pp. E418-E427 ◽  
Author(s):  
Sylvia Kroencke ◽  
Lutz Fischer ◽  
Björn Nashan ◽  
Lena Herich ◽  
Karl-Heinz Schulz
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Reference Data ◽  
First Year ◽  
Kidney Donors ◽  
A Prospective Study ◽  
Living Related

Empty nest or revolving door? A prospective study of women's quality of life in midlife during the phase of children leaving and re-entering the home

2002 ◽  
Vol 32 (3) ◽  
pp. 545-550 ◽  
Author(s):  
L. DENNERSTEIN ◽  
E. DUDLEY ◽  
J. GUTHRIE
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Mood State ◽  
Well Being ◽  
Household Composition ◽  
Daily Hassles ◽  
Revolving Door ◽  
First Year ◽  
Sexual Activities

Background. This study documents changes in household composition and effects on women's quality of life of children leaving and returning home.Methods. A 9-year annual prospective study of a population-based sample of mid-aged Australian-born women who were premenopausal at baseline (N = 438) was conducted. Documentation was made of household composition and change, well-being, bothersome symptoms, daily hassles, feelings for partner and frequency of sexual activities.Results. There was an increase in the number of women living alone, and a reduction in number of households in which there were children or parents. Each year >25% of women reported a change in household composition. In the first year after the last child departed (N = 155), there was an improvement in women's positive mood and total well-being and a reduction in negative mood and the number of daily hassles. This improvement in mood was confined to those women who at baseline were not worried about children leaving home. In the first year after children return home there was a trend towards reduced frequency of sexual activities but no mood changes.Conclusions. For the majority of women, the departure of the last child from the household leads to positive changes in women's mood state and a reduced number of daily hassles. Return of offspring may have an adverse effect on sexual relating of the parents.

A Prospective Study Assessing Nutritional Status in Treatment-NaïVE AL Amyloidosis Patients and the Effects of Malnutrition on Quality of Life and Survival

2011 ◽  
Vol 140 (5) ◽  
pp. S-864
Author(s):  
Prayman Sattianayagam ◽  
Thirusha Lane ◽  
Signe Risom ◽  
Simon D. Gibbs ◽  
Jennifer H. Pinney ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Prospective Study ◽  
Al Amyloidosis ◽  
Treatment Naïve ◽  
A Prospective Study

72: Quality of Life and Patient Satisfaction of Care Among Women with Urinary Incontinence: A Prospective Study

2007 ◽  
Vol 177 (4S) ◽  
pp. 25-26
Author(s):  
Simon Kim ◽  
Rodney L. Dunn ◽  
Edward J. McGuire ◽  
John O.L. DeLancey ◽  
John T. Wei
Keyword(s):  
Quality Of Life ◽  
Urinary Incontinence ◽  
Patient Satisfaction ◽  
Prospective Study ◽  
A Prospective Study

Kualitas Hidup Pasien Tuberkulosis Paru yang Mengalami Stigma Diri (Quality of Life Pulmonary Tuberculosis Patients With Self Stigma))

2019 ◽  
Vol 3 (2) ◽  
pp. 17-27
Author(s):  
Yunita Sari
Keyword(s):  
Quality Of Life ◽  
Pulmonary Tuberculosis ◽  
Descriptive Study ◽  
Negative Influence ◽  
Questionnaire Data ◽  
Average Quality ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Life Score

Pulmonary tuberculosis (TB) is a chronic disease that can bring about the sufferer's self-stigma and also affect his quality of life. A number of studies report that living with TB has a negative influence on the quality of life of sufferers even with or without self-stigma. The purpose of this study was to identify the quality of life of TB patients who experienced self-stigma. This research is a descriptive study, sample were 31 pulmonary TB patients. Data was collected using a questionnaire. Data analyzed by using frequency distribution and percentage. The researcher first screened TB patients who experienced self-stigma. The results showed that 25 people (80.64%) respondents experienced mild self-stigma. A total of 9 respondents (36%) had a quality of life score in the good category and as many as 16 respondents (64%) had enough category with an average quality of life score is 56.57. While respondents who had moderate self-stigma were 6 people (19.36%) with a good quality of life score was 1 person (16.67%) and enough category quality of life score were 5 people (83.33%) with an average quality of life score is 49.92.

Quality of Life Before and After Endovascular and Open Repair of Asymptomatic AAAs: A Prospective Study

2000 ◽  
Vol 7 (5) ◽  
pp. 372-379 ◽  
Author(s):  
Martin Malina ◽  
Marie Nilsson ◽  
Jan Brunkwall ◽  
Krasnodar Ivancev ◽  
Timothy Resch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Open Repair ◽  
Before And After ◽  
A Prospective Study

The effect of treatment and coping on the quality of life in breast cancer patients: a moderated mediation model

2021 ◽  
Author(s):  
Lorena Gutiérrez-Hermoso ◽  
Lilian Velasco-Furlong ◽  
Sofía Sánchez-Román ◽  
Elisabeth Berzal-Pérez ◽  
Natasha Alcocer-Castillejos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Moderated Mediation ◽  
Mediation Model ◽  
Breast Cancer Patients ◽  
Moderated Mediation Model ◽  
Effect Of Treatment ◽  
And Coping

The Impact of Self-Stigma, Role Strain, and Diabetes Distress on Quality of Life and Glycemic Control in Women With Diabetes: A 6-Month Prospective Study

2021 ◽  
pp. 109980042110096
Author(s):  
Ruey-Hsia Wang ◽  
Chia-Chin Lin ◽  
Shi-Yu Chen ◽  
Hui-Chun Hsu ◽  
Chiu-Ling Huang
Keyword(s):  
Quality Of Life ◽  
Glycemic Control ◽  
Prospective Study ◽  
Structural Equation ◽  
Role Strain ◽  
Diabetes Distress ◽  
Equation Modeling ◽  
Disease Characteristics ◽  
The Impact

Purposes: Women with diabetes (WD) are more severely impacted by the consequence of suboptimal diabetes control. This study aims to examine the impact of demographic and disease characteristics, baseline self-stigma, role strain, diabetes distress on Hemoglobin A1C (A1C) levels, quality of life (D-QoL) and 6-month A1C levels in younger WD. Methods: This study was a 6-month prospective study. In total, 193 WD aged 20–64 years were selected by convenience sampling from three outpatient clinics in Taiwan. Demographic and disease characteristics, self-stigma, role strain, diabetes distress, A1C levels, and D-QoL were collected at baseline. A1C levels were further collected 6 months later. Structural equation modeling was conducted to test the hypothesized model. Results: The final model supported that higher baseline D-QoL directly associated with lower concurrent A1C levels and indirectly associated with lower 6-month A1C levels through baseline A1C levels. Higher baseline self-stigma, role strain, and diabetes distress directly associated with lower baseline D-QoL, and indirectly associated with higher 6-month A1C levels through D-QoL. Conclusion: Improving self-stigma, role strain, and diabetes distress should be considered as promising strategies to improve D-QoL in young WD. D-QoL plays a mediation role between baseline self-stigma, role strain, diabetes distress and subsequent glycemic control in younger WD. Enhancing baseline D-QoL is fundamental to improve subsequent glycemic control.

scholarly journals Impact of malnutrition on health-related quality of life in persons receiving dialysis: a prospective study

2021 ◽  
pp. 1-24
Author(s):  
Daniela Viramontes-Hörner ◽  
Zoe Pittman ◽  
Nicholas M Selby ◽  
Maarten W Taal
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Health Related Quality ◽  
Poor Hrqol ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Impact ◽  
Over Time

Abstract Health-related quality of life (HRQoL) is severely impaired in persons receiving dialysis. Malnutrition has been associated with some measures of poor HRQoL in cross-sectional analyses in dialysis populations, but no studies have assessed the impact of malnutrition and dietary intake on change in multiple measures of HRQoL over time. We investigated the most important determinants of poor HRQoL and the predictors of change in HRQoL over time using several measures of HRQoL. We enrolled 119 haemodialysis and 31 peritoneal dialysis patients in this prospective study. Nutritional assessments (Subjective Global Assessment [SGA], anthropometry and 24-hour dietary recalls) and HRQoL questionnaires (Short Form-36 [SF-36] mental [MCS] and physical component scores [PCS] and European QoL-5 Dimensions [EQ5D] health state [HSS] and visual analogue scores [VAS]) were performed at baseline, 6 and 12 months. Mean age was 64(14) years. Malnutrition was present in 37% of the population. At baseline, malnutrition assessed by SGA was the only factor independently (and negatively) associated with all four measures of HRQoL. No single factor was independently associated with decrease in all measures of HRQoL over 1 year. However, prevalence/development of malnutrition over one year was an independent predictor of 1-year decrease in EQ5D HSS and 1-year decrease in fat intake independently predicted the 1-year decline in SF-36 MCS and PCS, and EQ5D VAS. These findings strengthen the importance of monitoring for malnutrition and providing nutritional advice to all persons on dialysis. Future studies are needed to evaluate the impact of nutritional interventions on HRQoL and other long-term outcomes.

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