scholarly journals Serum parathyroid hormone level is associated with body mass index. The 5th Tromso study

2004 ◽  
pp. 167-172 ◽  
Author(s):  
E Kamycheva ◽  
J Sundsfjord ◽  
R Jorde
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Relative Risk ◽  
Body Mass ◽  
Serum Calcium ◽  
Population Based ◽  
Serum Parathyroid Hormone ◽  
Serum Pth

OBJECTIVE: To study whether serum parathyroid hormone (PTH) and serum calcium are associated with body mass index (BMI), and their predicting role in obesity. DESIGN: Population based, cross-sectional study. METHODS: In 2001 a population-based health survey was held in Tromso, North Norway. Questionnaires on medical history and life-style factors were completed and anthropometric data were collected. Calcium and vitamin D intakes and a physical activity score were calculated. Serum calcium and PTH were measured in a subset of 3447 men and 4507 women. Pearson correlation and linear regression were used to evaluate associations between BMI, PTH and serum calcium, and logistic regression was used to test PTH and serum calcium as predictors of obesity and to calculate odds ratio. Relative risk was calculated using frequency tables. RESULTS: For serum calcium and PTH there was a significant positive relation to BMI in both genders (P<0.001), which to our knowledge has not previously been reported on the basis of a large epidemiological study. Age, low calcium and vitamin D intakes were explanatory variables for serum PTH. The highest quartile of serum PTH (>4.20 pmol/l) was a significant predictor for obesity (P<0.001) in both genders, adjusted for age, physical activity and serum calcium. Obesity rates were higher in those with PTH levels in the highest quartile compared with those in the lower quartiles, which resulted in a relative risk of 1.40 (95% confidence interval (C.I.) 1.20-1.60) for men and 1.48 (95% C.I. 1.31-1.67) for women. CONCLUSIONS: Serum PTH, adjusted for age, physical activity and serum calcium, is positively associated with BMI in both sexes, and serum PTH is an independent predictor of obesity in our statistical model.

Moderators of the Association Between Serum Parathyroid Hormone and Metabolic Syndrome in Participants with Elevated Parathyroid Hormone: NHANES 2003–2006

2020 ◽  
Vol 52 (07) ◽  
pp. 509-516
Author(s):  
Liang Chen ◽  
Jian-Hao Pei ◽  
Jian Kuang
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Protein Intake ◽  
Elevated Serum ◽  
Vitamin D Supplementation ◽  
Serum Parathyroid Hormone ◽  
Severity Scores ◽  
Serum Pth

AbstractThis cross-sectional study extracted data of 392 NHANES participants with elevated serum parathyroid hormone (PTH) concentrations from 2 cycles of the US National Health and Nutrition Examination Survey (NHANES) 2003–2006 and evaluated the association between serum (PTH) concentration and metabolic syndrome (MetS) to identify dietary and lifestyle factors that may modify that association. The primary outcome was MetS severity scores. Results of univariate linear regression analyses revealed that serum PTH concentrations correlated positively and significantly with MetS severity scores (β=0.399, p=0.030). After adjusting for gender, age, race, and alcohol consumption, results of multivariate analysis revealed that increased serum PTH concentration correlated significantly with higher MetS severity scores (β=0.413, p=0.045) in participants with moderate physical activity over the past 30 days. Serum PTH concentration also correlated significantly with higher MetS severity scores in participants with serum 25-hydroxyvitamin D deficiency (β=0.456 and p=0.014), those without vitamin D supplementation (β=0.524, p=0.028) and with higher protein intake (β=0.586 and p=0.030). In conclusion, increased serum PTH concentration is associated with higher MetS severity scores in participants with elevated serum PTH at baseline. The association between PTH concentration and MetS severity is moderated by participants’ physical activity levels, status of serum vitamin D, vitamin D supplementation, and daily protein intake.

scholarly journals Parathyroid hormone in Sri Lankan pregnant women: Vitamin D and other determinants

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258381
Author(s):  
Anusha Kaneshapillai ◽  
Usha Hettiaratchi ◽  
Shamini Prathapan ◽  
Guwani Liyanage
Keyword(s):  
Vitamin D ◽  
Regression Analysis ◽  
Parathyroid Hormone ◽  
Pregnant Women ◽  
Serum Calcium ◽  
Educational Level ◽  
Venous Blood ◽  
Sri Lankan ◽  
Serum Parathyroid Hormone ◽  
Cross Sectional

Introduction Determinants of parathyroid hormone level during pregnancy have been less frequently studied. We aimed to describe the serum parathyroid hormone (PTH) and its determinants in Sri Lankan pregnant women in a community setting. Materials and methods In this cross-sectional analysis, 390 pregnant mothers in their third trimester were enrolled from primary care centers of 15 health divisions in the Colombo District in Sri Lanka. Venous blood was analyzed for a total 25-hydroxyvitamin-D [25(OH)D], serum parathyroid hormone (PTH), serum calcium, and alkaline phosphatase. The bone quality was assessed in terms of speed of sound (SOS) using the quantitative ultrasound scan (QUS). Univariate and multivariate regression analysis was used to examine the determinants of PTH concentration in blood. Results Median serum 25(OH)D was 17.5ng/mL. Most (61.6%) were vitamin D deficient (<20ng/mL). Median PTH was 23.7pg/mL. Only 0.8% had hyperparathyroidism (PTH >65pg/mL). The correlation between 25(OH)D and PTH was weak but significant (r = -0.197; p<0.001). SOS Z-score was below the cut-off (≤−2) in fifty-six women (14.7%), and SOS did not relate significantly to PTH. In regression analysis, serum 25(OH)D, serum calcium, body mass index, educational level, and weeks of pregnancy were significant independent variables when adjusted. The model explained 16% of the variation in the PTH level. Conclusions A high prevalence of vitamin D deficiency was observed among Sri Lankan pregnant women in the present study. Serum 25(OH)D, calcium, weeks of pregnancy, and educational level were determinants of serum PTH.

scholarly journals Association of Probiotic Consumption and Body Mass Index in the US Population: Insights from NHANES (P21-022-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Ajita Jadhav ◽  
Kathleen Melanson
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Mass ◽  
Antibiotic Use ◽  
Population Based ◽  
Cross Sectional Study ◽  
Healthy Eating Index ◽  
Weighted Mean ◽  
Cross Sectional ◽  
Supplement Use

Abstract Objectives To determine the association between probiotic consumption through food or supplements and Body Mass Index (BMI) in National Health And Nutrition Examination Survey (NHANES) data. Methods This large US population based cross-sectional study includes 2005–2014 NHANES data. We utilized 24-hour Dietary Recall (DR) interviews and Dietary Supplement Use 30-Day recall (DSQ) to extract the Probiotic Food (PF) and Probiotic Supplements (PS) consumption, respectively, using text search terms. Adults (≥18 years), who responded to DR interviews and DSQ, were included, while pregnant women were excluded from the study. Differences in probiotic consumers and non-consumers were assessed with χ2/Wilcoxon tests. To assess the relationship among probiotic consumption and BMI, we performed multiple linear regression while adjusting for confounders such as gender, race, age, Healthy Eating Index (HEI), Kcal consumption, physical activity and antibiotic use. Results of associations were analyzed separately for PF and PS, and weighted to reflect national estimates. Results Study included 15,104,111 (13.8%) PF consumers and 94,421,839 (86.2%) non-consumers. PF consumers were generally female (63.2% vs. 51.6%), white (77.6% vs. 67.1%), older [mean (±SD) 48.54 ± 0.99 vs. 46.29 ± 0.55 years], had higher HEI [57.52 ± 0.86 vs. 52.33 ± 0.37] and Kcal consumption [3861.77 ± 63.70 vs. 3737.49 ± 31.62], but similar physical activity (46.9% vs. 46.9%) and antibiotic use (4.9% vs. 4.6%) compared to non-consumers. We also identified 1108,619 (1.1%) PS users and 101,698,442 (98.9%) non-users. Compared to non-users, PS users were commonly female (67.8% vs. 51.8%), white (84.5% vs. 66.4%), older [52.60 ± 3.11 vs. 46.36 ± 1.06 years], had higher HEI [60.92 ± 2.41 vs. 52.70 ± 0.37], similar physical activity (45.3% vs. 45.0%) and Kcal Consumption [3599.08 ± 182.06 vs. 3737.43 ± 31.83], but more antibiotic users (9.4% vs. 4.5%). After adjusting for confounders, the weighted mean BMI was 0.48 kg/m2 [95% Confidence Interval (CI) = (−0.68) – (−0.28)] lower for PF consumers than non-consumers. PS users had even lower weighted mean BMI [−1.10 kg/m2, 95% CI = (−1.71) – (−0.48)] compared to non-users. Conclusions In this large nationally representative population-based study, probiotic consumption via food or supplement was associated with lower body mass index. Funding Sources None.

scholarly journals RELATION OF COMMON MENTAL DISORDER, PHYSICAL ACTIVITY AND BODY MASS INDEX IN WOMEN, POPULATION-BASED STUDY

2017 ◽  
Vol 28 (1) ◽  
Author(s):  
Isadora Ferreira Henriques ◽  
Isabel Aparecida Porcatti de Walsh ◽  
Maria Cristina Cortez Carneiro Meirelles ◽  
Gilberto de Araújo Pereira ◽  
Shamyr Sulyvan de Castro
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Mental Disorder ◽  
Body Mass ◽  
Common Mental Disorder ◽  
Population Based ◽  
Population Based Study

scholarly journals Physical activity and body mass index in elderly Iranians in Sweden: a population-based study

2007 ◽  
Vol 62 (11) ◽  
pp. 1326-1332 ◽  
Author(s):  
A Koochek ◽  
S-E Johansson ◽  
T O Kocturk ◽  
J Sundquist ◽  
K Sundquist
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Mass ◽  
Population Based ◽  
Population Based Study

scholarly journals Associations of Lifestyle and Anthropometric Factors With the Risk of Herpes Zoster: A Nationwide Population-Based Cohort Study

2021 ◽  
Author(s):  
Sigrun A J Schmidt ◽  
Henrik Toft Sørensen ◽  
Sinéad M Langan ◽  
Mogens Vestergaard
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Herpes Zoster ◽  
Alcohol Consumption ◽  
Body Mass ◽  
Cox Regression ◽  
Smoking Status ◽  
Population Based ◽  
Normal Weight ◽  
Hazard Ratios

Abstract The role of lifestyle in development of herpes zoster remains unclear. We examined whether smoking status, alcohol consumption, body mass index, or physical activity were associated with zoster risk. We followed a population-based cohort of 101,894 respondents to the 2010 Danish National Health Survey (baseline, May 1, 2010) until zoster diagnosis, death, emigration, or July 1, 2014, whichever occurred first. We computed hazard ratios for zoster associated with each exposure, using Cox regression with age as the time scale and adjusting for potential confounders. Compared with never smokers, hazards for zoster were increased in former smokers (1.17, 95% confidence interval (CI): 1.06, 1.30), but not in current smokers (1.00, 95% CI: 0.89, 1.13). Compared with low-risk alcohol consumption, neither intermediate-risk (0.95, 95% CI: 0.84, 1.07) nor high-risk alcohol consumption (0.99, 95% CI: 0.85, 1.15) was associated with zoster. We also found no increased hazard associated with weekly binge drinking versus not (0.93, 95% CI: 0.77, 1.11). Risk of zoster varied little by body mass index (referent = normal weight) and physical activity levels (referent = light level), with hazard ratios between 0.96 and 1.08. We observed no dose-response association between the exposures and zoster. The examined lifestyle and anthropometric factors thus were not risk factors for zoster.

scholarly journals Assessment of serum vitamin D levels in Egyptian children with beta-thalassemia major

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Ghada Saad Abdelmotaleb ◽  
Ola Galal Behairy ◽  
Khalid Eid Abd El Azim ◽  
Dalia Mohamed Abd El-Hassib ◽  
Tasbeh Mohamed Hemeda
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Body Mass ◽  
Serum Calcium ◽  
Serum Levels ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Beta Thalassemia Major ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

Abstract Background Beta-thalassemia major patients are at increased risk of complications including endocrinopathies and bone disease due to iron overload. So, this study aimed to assess the growth parameters, serum levels of 25-OH-vitamin D, calcium, and phosphorous in children with beta-thalassemia major. This was a case-control study that included 55 children with beta-thalassemia major compared with 30 sex- and age-matched healthy children that served as a control group. All enrolled children were subjected to full history taking, clinical examination including anthropometric measurements, and laboratory investigations including complete blood count, serum ferritin, levels of serum calcium, phosphorus, and 25-OH-vitamin D. Results Body mass index was statistically significantly lower in the thalassemic group (P < 0.001). It was observed that vitamin D levels were significantly lower in thalassemic patients than in controls (P value < .0001). The mean serum 25-OH-vitamin D levels were 19.84 ± 5.79 ng/ml and 44.98 ± 5.77 ng/ml, respectively; 22 cases (40%) had insufficient vitamin D, and 5 cases (9%) had deficient vitamin D. Regarding serum calcium and phosphorous, there was no significant difference between the thalassemic and control groups. Conclusion Children with beta-thalassemia major had low body mass index and metabolic abnormality in the form of lower serum levels of vitamin D that signify the importance of therapeutic interventions.

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