Endocrine complications of thalassemia and its treatment: a local experience

2014 ◽  
Author(s):  
Serena Deller ◽  
Radhika Mistry ◽  
Wyn Burbridge ◽  
Shivan Pancham ◽  
Christine Wright ◽  
...  
Author(s):  
Fatima Almousa ◽  
Haya Alhaqbani ◽  
Rima lsagga ◽  
Abrar Alshehri ◽  
Ibrahim Alsarra

2020 ◽  
Vol 14 (4) ◽  
pp. 44
Author(s):  
O. V. Kelasyev

The article probes into the conflicts in the local self-government bodies of St. Petersburg which unfold after the election held September 8th, 2019. A fairly large number of so-called “independent” deputies were elected to several district councils, where their activities contravene the prevailing behaviour patterns of the local deputies elected earlier. There have been conflicts with groups of traditionalist deputies and local administrations, there has been a general increase in conflicts within the local self-government bodies. These conflicts are of specific character. Their subjects are tradition-oriented local deputies (“traditionalists”) and new groups of deputies mostly comprising young people (“innovators”) joined by local activists, many of whom ran for a seat in the district council but lost the election, as well as deputies of St. Petersburg Legislative Assembly and district administrations. The object of the conflicts may lie in a local resource, status (leadership, power in the district) and the deputies’ value orientations which are sometimes determined by a significant disparity in age, mentality or life experiences. The intensification of conflict introduced by the “innovators” has both negative and positive features. The negative ones include delays in decision-making, increasing tension, aggravation of the overall negative emotions, rejection of the existing local experience which in many cases is positive. The positive features include a strengthening political competition, democratization, mutual control, actual inclusion of the population in decision-making processes. Furthermore, there is a transition of interaction between the local authorities and residents from the level of manipulation and neglect to an equitable partnership, improvement of self-organization processes among the population and grass-roots local initiatives. It would seem that the positive features outweigh the negative ones.


2020 ◽  
Vol 20 (1) ◽  
pp. 10-42
Author(s):  
Flora Mary Bartlett

I examine how tensions between locals, environmentalists, and State politicians in a small town in northern Sweden are reinforced through national discourses of climate change and sustainability. Turbulence emerges across different scales of responsibility and environmental engagement in Arjeplog as politicians are seen by local inhabitants to be engaging more with the global conversation than with the local experience of living in the north. Moreover, many people view the environmentalist discourses from the politicians in the south, whom they deem to be out of touch with rural life, as threatening to the local experience of nature. These discourses pose a threat to their reliance on petrol, essential for travel, and are experienced locally as a continuation of the south’s historical interference in the region. Based on thirteen months of field research, I argue that mistrust of the various messengers of climate change, including politicians and environmentalists, is a crucial part of the scepticism towards the climate change discourse and that we as researchers need to utilise the strengths of anthropology in examining the reception (or refusal) of climate change. The locals’ mistrust of environment discourses had implications for my positionality, as I was associated with these perceived ‘outsider’ sensibilities. While the anthropology of climate change often focusses on physical impacts and resilience, I argue that we need to pay due attention to the local turbulence surrounding the discourses of climate change, which exist alongside the physical phenomena.  


2014 ◽  
Vol 81 (1) ◽  
pp. 32-42 ◽  
Author(s):  
Shlomit Shalitin ◽  
Elad Laur ◽  
Yael Lebenthal ◽  
Shifra Ash ◽  
Isaac Yaniv ◽  
...  

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
M Gonzalez ◽  
M Aker ◽  
P Manjunath ◽  
A Mishra ◽  
N Ward

Abstract Introduction Post-operative intra-abdominal adhesions remain the leading cause of small bowel obstruction (SBO) representing one of the main diagnoses warranting emergency laparotomies. The National Audit in Small Bowel Obstruction advocates the use of water-soluble contrast agents (WSCA) as initial management of SBO. We aim to assess the role and outcomes of WSCA and its rate in successfully managing SBO non-operatively. Method We conducted a 2-year retrospective analysis including all patients admitted with adhesive SBO. Outcomes of patients who received WSCA were compared to those who hadn’t. Results 118 patients were included, 27(23%) of which required immediate surgery while 91(77%) were initially managed conservatively. From the latter group, 53(58.2%) received WSCA whilst 38(41.8%) didn’t. Of the group that received WSCA, 36(39.5%) were successfully managed non-operatively, compared to 26(28.5%) that didn’t, this however lacked statistical significance. LOS didn’t differ between these two groups (5 days vs. 5.5 days, p = 0.805). 32% of the patients required eventual surgical intervention needing longer LOS regardless of receiving WSCA (6.6 days vs. 13.6 days p < 0.001). Conclusions Adhesive SBO can be managed conservatively in up to two-thirds of patients. WSCA usage has a positive impact but needs further assessment in larger studies.


ESMO Open ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 100011
Author(s):  
S.A. Paschou ◽  
K. Stefanaki ◽  
T. Psaltopoulou ◽  
M. Liontos ◽  
K. Koutsoukos ◽  
...  

Endocrines ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 241-250
Author(s):  
Marta Araujo-Castro ◽  
Eider Pascual-Corrales ◽  
Héctor Pian ◽  
Ignacio Ruz-Caracuel ◽  
Alberto Acitores Cancela ◽  
...  

Purpose: to determine whether pre-surgical treatment using long-acting somatostatin analogues (SSAs) may improve surgical outcomes in acromegaly. Methods: retrospective study of 48 patients with acromegaly operated by endoscopic transsphenoidal approach and for first time. Surgical remission was evaluated based on the 2010 criteria. Results: most patients, 83.3% (n = 40), harbored macroadenomas and 31.3% (n = 15) invasive pituitary adenomas. In this case, 14 patients were treated with lanreotide LAR and 6 with octreotide LAR, median monthly doses of 97.5 [range 60–120] and 20 [range 20–30] mg, respectively, for at least 3 months preoperatively. Presurgical variables were comparable between pre-treated and untreated patients (p > 0.05). Surgical remission was more frequent in those pre-treated with monthly doses ≥90 mg of lanreotide or ≥30 mg of octreotide than in untreated or pre-treated with lower doses (OR = 4.64, p = 0.025). However, no differences were found between pre-treated and untreated patients when lower doses were included or between those treated for longer than 6 months compared to those untreated or pre-treated for shorter than 6 months. Similarly, no differences were found either in terms of surgical or endocrine complications (OR = 0.65, p = 0.570), independently of the doses and the duration of SSA treatment (p > 0.05). Conclusions: the dose of SSAs is a key factor during pre-surgical treatment, since the beneficial effects in surgical remission were observed with monthly doses equal or higher than 90 mg of lanreotide and 30 mg of octreotide, but not with lower doses.


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