Intra-adrenal cytokine expression during inflammatory stress is immune-dependent

2017 ◽  
Author(s):  
Daniel Fudulu ◽  
George Horn ◽  
Georgina Hazell ◽  
Gianni Angelini ◽  
Stafford Lightman ◽  
...  
2007 ◽  
Vol 230 (3) ◽  
pp. 384-384
Author(s):  
Michael S. Davis ◽  
Caroline C. Williams ◽  
James H. Meinkoth ◽  
Jerry R. Malayer ◽  
Christopher M. Royer ◽  
...  
Keyword(s):  

Author(s):  
Nese Unver

: Cancer stem cells represent a rare subpopulation of cancer cells carrying self-renewal and differentiation features in the multi-step tumorigenesis, tumor recurrence and metastasis. Pro-inflammatory stress is highly associated with cancer stemness via induction of cytokines, tumor-promoting immune cells and cancer stemness-related signaling pathways. This review summarizes the major pro-inflammatory factors affecting cancer stem cell characteristics and the critical immunotherapeutic strategies to eliminate cancer stem cells.


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