scholarly journals Effects of hypophysectomy and of LH administration on luteal phase plasma progesterone levels in the beagle bitch

Reproduction ◽  
1980 ◽  
Vol 58 (2) ◽  
pp. 407-410 ◽  
Author(s):  
P. Concannon
Keyword(s):  
Luteal Phase ◽  
Plasma Progesterone

The use of salivary progesterone assays in the assessment of ovarian function in postmenarcheal girls

1984 ◽  
Vol 102 (2) ◽  
pp. 265-268 ◽  
Author(s):  
G. F. Read ◽  
D. W. Wilson ◽  
I. A. Hughes ◽  
K. Griffiths
Keyword(s):  
Luteal Phase ◽  
Ovarian Function ◽  
Age Groups ◽  
Premenopausal Women ◽  
Chronological Age ◽  
First Year ◽  
Published Data ◽  
Sufficient Data ◽  
Plasma Progesterone ◽  
Probable Occurrence

ABSTRACT Menstrual cycle profiles of salivary progesterone were derived from daily samples obtained from 75 postmenarcheal girls aged between 12 and 17 years. Data were analysed to establish the proportion of girls exhibiting ovulatory cycles in each of several age groups following menarche or in groups based solely on chronological age. 'Luteal'-phase profiles of salivary progesterone, which were similar in shape to those characteristic of mature premenopausal women, were taken to indicate the probable occurrence of ovulation. The percentage of cycles in those subjects judged to be ovulatory, grouped according to gynaecological age, rose from 14% in the first year to 56% in the fourth year. Those classified according to chronological age, and where sufficient data permitted reliable estimates of the percentage of subjects ovulating, rose from 11% at 12 years of age to 64% for girls aged 16. These data are in reasonable concordance with published data using plasma progesterone and urinary methods for establishing ovulatory incidence, and indicate the value of salivary progesterone measurements in studies of ovarian function in adolescence. J. Endocr. (1984) 102, 265–268

Decreased thermal conductance during the luteal phase of the menstrual cycle in women

1990 ◽  
Vol 69 (6) ◽  
pp. 2029-2033 ◽  
Author(s):  
P. Frascarolo ◽  
Y. Schutz ◽  
E. Jequier
Keyword(s):  
Menstrual Cycle ◽  
Thermal Equilibrium ◽  
Luteal Phase ◽  
Thermal Conductance ◽  
Heat Losses ◽  
Tympanic Temperature ◽  
Whole Body ◽  
Direct Calorimetry ◽  
Plasma Progesterone ◽  
Metabolic Heat

To study the influence of the menstrual cycle on whole body thermal balance and on thermoregulatory mechanisms, metabolic heat production (M) was measured by indirect calorimetry and total heat losses (H) were measured by direct calorimetry in nine women during the follicular (F) and the luteal (L) phases of the menstrual cycle. The subjects were studied while exposed for 90 min to neutral environmental conditions (ambient temperature 28 degrees C, relative humidity 40%) in a direct calorimeter. The values of M and H were not modified by the phase of the menstrual cycle. Furthermore, in both phases the subjects were in thermal equilibrium because M was similar to H (69.7 +/- 1.8 and 72.1 +/- 1.8 W in F and 70.4 +/- 1.9 and 71.4 +/- 1.7 W in L phases, respectively). Tympanic temperature (Tty) was 0.24 +/- 0.07 degrees C higher in the L than in the F phase (P less than 0.05), whereas mean skin temperature (Tsk) was unchanged. Calculated skin thermal conductance (Ksk) was lower in the L (17.9 +/- 0.6 W.m-2.degrees C-1) than in the F phase (20.1 +/- 1.1 W.m-2.degrees C-1; P less than 0.05). Calculated skin blood flow (Fsk) was also lower in the L (0.101 +/- 0.008 l.min-1.m-2) than in the F phase (0.131 +/- 0.015 l.min-1.m-2; P less than 0.05). Differences in Tty, Ksk, and Fsk were not correlated with changes in plasma progesterone concentration. It is concluded that, during the L phase, a decreased thermal conductance in women exposed to a neutral environment allows the maintenance of a higher internal temperature.

Catamenial Variations in Erythrocyte Sodium–Lithium Countertransport and Blood Pressure

1997 ◽  
Vol 93 (1) ◽  
pp. 29-34 ◽  
Author(s):  
G. I. Adebayo ◽  
L. Hemeryck ◽  
M. Hall ◽  
D. Gasparro ◽  
M. Sinnott ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Menstrual Cycle ◽  
Luteal Phase ◽  
Diastolic Pressure ◽  
Plasma Progesterone ◽  
Future Studies ◽  
Temporal Study ◽  
Erythrocyte Sodium ◽  
Two Parameters ◽  
Plasma Oestradiol

1. We undertook a temporal study of external sodium-stimulated lithium efflux (sodium—lithium countertransport) in erythrocytes and blood pressure by measuring these two parameters in three phases of the menstrual cycle (menstrual, midcycle and luteal phases) in 22 healthy, non-medicated females with regular menstrual cycles. Plasma oestradiol and progesterone levels were also determined. 2. Sodium—lithium countertransport activity (activity in 140 mmol/1 external NaCl) in the midcycle phase (0.176 ± 0.017 mmol h−1 l−1 of cells) was lower than in the menstrual (0.192 ± 0.016 mmol h−1 l−1 of cells, P < 0.030) and luteal (0.203 ± 0.018 mmol h−1 l−1 of cells, P < 0.030) phases. The Vmax of the transporter changed similarly but the Km was unaltered. 3. The plasma oestradiol level was 628.9 ± 39.1 pmol/1 in the midcycle phase, higher than in the menstrual (232 ± 18.5 pmol/1, P < 0.001) and luteal (372.5 ± 28.1 pmol/1, P < 0.001) phases. The progesterone level was 28.6 ± 2.1 nmol/1 in the luteal phase, and values were lower in the menstrual (2.5 ± 0.3 nmol/1, P < 0.001) and midcycle (2.8 ± 0.4 nmol/1, P < 0.001) phases. 4. There was no correlation between plasma oestradiol and sodium—lithium countertransport activity or Vmax during the menstrual cycle, but plasma progesterone was positively correlated with sodium—lithium countertransport activity (r = 0.478, P < 0.025, n = 22) and Vmax (r = 0.551, P < 0.045, n = 14) in the luteal phase. 5. Systolic blood pressure did not change significantly during the menstrual cycle. However, the diastolic pressure showed variation similar to that in sodium—lithium countertransport activity/Vmax, its midcycle value of 66.6 ± 1.4 mmHg being lower than that in the luteal (71.6 ± 1.3 mmHg, P < 0.025) and menstrual (70.6 ± 1.4 mmHg, P < 0.025) phases. 6. We conclude that sodium—lithium countertransport activity exhibits catamenial variation. Therefore we suggest, given this observation, that blood sampling for the assessment of the state of activity of the transport system be standardized in relation to a phase of the menstrual cycle in future studies involving females.

scholarly journals Delayed effect of low progesterone concentrations on bovine uterine PGF(2alpha) secretion in the subsequent oestrous cycle

Reproduction ◽  
2001 ◽  
pp. 643-648 ◽  
Author(s):  
A Shaham-Albalancy ◽  
Y Folman ◽  
M Kaim ◽  
M Rosenberg ◽  
D Wolfenson
Keyword(s):  
Corpus Luteum ◽  
Luteal Phase ◽  
Oestrous Cycle ◽  
Delayed Effect ◽  
Plasma Progesterone ◽  
Progesterone Secretion ◽  
Progesterone Treatment ◽  
Late Luteal Phase ◽  
Subsequent Cycle ◽  
Concentration Curves

Low progesterone concentrations during the bovine oestrous cycle induce enhanced responsiveness to oxytocin challenge late in the luteal phase of the same cycle. The delayed effect of low progesterone concentrations during one oestrous cycle on uterine PGF(2alpha) secretion after oxytocin challenge on day 15 or 16 of the subsequent cycle was studied by measuring the concentrations of the major PGF(2alpha) metabolite (13,14-dihydro-15-keto PGF(2alpha); PGFM) in plasma. Two experiments were conducted, differing in the type of progesterone treatment and in the shape of the low progesterone concentration curves. In Expt 1, progesterone supplementation with intravaginal progesterone inserts, with or without an active corpus luteum, was used to obtain high, or low and constant plasma progesterone concentrations, respectively. In Expt 2, untreated cows, representing high progesterone treatment, were compared with cows that had low but increasing plasma progesterone concentrations that were achieved by manipulating endogenous progesterone secretion of the corpus luteum. Neither experiment revealed any differences in plasma progesterone concentrations between the high and low progesterone groups in the subsequent oestrous cycle. In both experiments, both groups had similar basal concentrations of PGFM on day 15 (Expt 1) or 16 (Expt 2) of the subsequent oestrous cycle, 18 days after progesterone treatments had ended. In both experiments, the increases in PGFM concentrations in the low progesterone groups after an oxytocin challenge were markedly higher than in the high progesterone groups. These results indicate that low progesterone concentrations during an oestrous cycle have a delayed stimulatory effect on uterine responsiveness to oxytocin during the late luteal phase of the subsequent cycle. This resulting increase in PGF(2alpha) secretion may interfere with luteal maintenance during the early stages of pregnancy.

445 RELATIONSHIPS OF LUTEAL PHASE VARIABLES (PRIOR TO AI) WITH FOLLICULAR WAVES IN WATER BUFFALOES

2010 ◽  
Vol 22 (1) ◽  
pp. 379
Author(s):  
H. Kohram ◽  
G. Mohammadi ◽  
E. Dirandeh
Keyword(s):  
Luteal Phase ◽  
Ultrasound Examination ◽  
Limit Of Detection ◽  
Area Under The Curve ◽  
Prostaglandin F2α ◽  
Control Treatment ◽  
Estrous Cycles ◽  
Plasma Progesterone ◽  
Blood Samples ◽  
Follicular Waves

This study was done to consider relationships of luteal phase variables (prior to AI) with follicular waves. The estrous cycles of 15 buffaloes were synchronized with 2 i.m. injections of prostaglandin F2α given 11 days apart. The buffaloes were randomly assigned to 1 of 3 treatments. Buffaloes in the control treatment received no treatment, whereas G6 buffalos received a GnRH injection between Day 5 and 7 and G16 buffalos received a GnRH injection between Day 15 and 17 of the estrous cycle (estrus = Day 0). Daily, from estrus Day 0 to the next estrus Day 23, buffaloes had their ovaries scanned by ultrasound. Blood samples were collected by tail following each ultrasound examination from estrus until next estrus (estrus = 0). Concentrations of plasma progesterone were determined by radioimmunoassay kit. The limit of detection of the assay was 0.1 45 ng mL-1 and the intra- and interassay coeffients of variation were 7.4% and 9.2%, respectively. Data were analyzed by using PROC GLM of SAS (SAS Institute, Cary, NC, USA). For comparisons between groups, the 2-sample t-test was used for continuous traits, such as size of CL or hormone concentrations. Prospective comparisons of indices of progesterone indicated that the length of luteal lifespan was longer in 3-wave than in 2-wave buffaloes (P < 0.01). Plasma progesterone concentrations were similar at peak and measured as area under the curve on Day 5 through 17 preceding insemination in 2-wave (5.30 ± 0.40 ng mL-1) and 3-wave buffaloes (5.10 ± 0.20 ng mL-1). Length of the luteal phase (defined as from the day of estrus until the last day on which plasma progesterone remained >2 ng mL-1) was <2 days shorter in 2-wave buffaloes than in 3-wave buffaloes (15.20 ± 0.40 v. 17.10 ± 0.50 d; P < 0.05). In addition, the day of peak progesterone occurred earlier in 2-wave buffaloes (13.50 ± 0.30 v. 15.30 ± 0.70 d; P < 0.05).

scholarly journals Correlation between endometrial dating of luteal phase days 6 and 10 of the same menstrual cycle

1998 ◽  
Vol 116 (3) ◽  
pp. 1734-1737 ◽  
Author(s):  
Jorge Haddad Filho ◽  
Agnaldo Pereira Cedenho ◽  
Vilmon de Freitas
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Endometrial Thickness ◽  
Human Reproduction ◽  
Progesterone Level ◽  
Ovulatory Cycle ◽  
Plasma Progesterone ◽  
Menstrual Cycles ◽  
Infertile Couples ◽  
Study Setting

CONTEXT: Endometrial maturation, important in the diagnosis of infertile couples, has been evaluated since 1950 using the Noyes criteria. Nevertheless, there is no consensus regarding the most suitable period of the luteal phase for performing the biopsy. OBJETIVE: This study evaluated the correlation between the histological dating of two endometrial biopsies performed in the same menstrual cycle, on luteal phase days six and ten. DESIGN: Prospective study. SETTING: Human Reproduction Division of the Federal University of São Paulo, referral center. PATIENTS:Twenty-five women complaining of infertility had their menstrual cycles monitored by ultrasound and LH plasma levels, to obtain evidence of ovulation. PROCEDURES: Endometrial biopsies were performed on luteal phase days LH+6 and LH+10 (luteal phase day 1 = LH+1 = the day that follows LH peak). Dating was done according to morphometric criteria, in which an endometrium sample is considered out of phase if the minimum maturation delay is one day. On day LH+6, blood was drawn for plasma progesterone level determination. RESULTS: All patients had an ovulatory cycle (mean LH peak: 47.4 U/L; mean follicular diameter on LH peak day: 18.9 mm; mean endometrial thickness on LH peak day: 10.3 mm; mean plasma progesterone level on day LH+6: 14.4 ng/ml). 14 patients had both biopsies in phase; 5 patients had out of phase biopsies only on day LH+6; 3 had out of phase biopsies only on day LH+10 and 3 patients had out of phase biopsies on both days. McNemar's test showed no statistical difference between these data (p>33.36%). CONCLUSIONS: The correlation found between the endometrial datings suggests that biopsies performed on either of these two days are suitable for evaluation of endometrial maturation.

LUTEINIZING HORMONE (LH) AND PROGESTERONE IN PLASMA AND LH AND OESTROGENS IN URINE DURING 42 NORMAL MENSTRUAL CYCLES

1971 ◽  
Vol 68 (3) ◽  
pp. 502-512 ◽  
Author(s):  
Elof D. B. Johansson ◽  
Leif Wide ◽  
Carl Gemzell
Keyword(s):  
Luteinizing Hormone ◽  
Urinary Excretion ◽  
Plasma Levels ◽  
Luteal Phase ◽  
Maximum Level ◽  
Plasma Progesterone ◽  
Menstrual Cycles ◽  
Normal Menstrual Cycle ◽  
The Mean ◽  
Second Peak

ABSTRACT The plasma levels of luteinizing hormone (LH) and progesterone and the urinary excretion of LH and oestrogens were measured during the normal menstrual cycle of 22 young and healthy women. A total of 42 cycles were investigated. The urinary excretion of total oestrogens increased during several days before the rise of LH in the urine. The day of maximum excretion of LH and total oestrogens coincided during the midcycle period. The mid-cyclic rise in LH was found to occur on the same day in the plasma and urine and the days of maximum values coincided in 11 out of 16 cycles. In 5 cycles the maximum level was reached one day later in the urine. The plasma levels of progesterone started to increase during the LH and oestrogen peaks. The days for maximum levels of progesterone coincided with the second peak of urinary oestrogens. The levels of progesterone in the plasma reached values above 10 ng per ml in all normal cycles. The plasma levels of progesterone were below 1 ng per ml plasma when menstrual bleeding started. The length of the luteal phase was 14.4 ± 1.1 (s) days. The sum of daily urinary excretion of total oestrogens and the sum of the daily plasma progesterone levels varied within 15 per cent of the mean in five out of six women studied during more than two cycles. The variation in values for the sums of daily oestrogen excretion and plasma progesterone levels was considerably larger between menstrual cycles of different women than between menstrual cycles of the same woman.

Effects of naloxone and electroacupuncture treatment on plasma concentrations of LH in sheep

1984 ◽  
Vol 101 (1) ◽  
pp. 75-80 ◽  
Author(s):  
P. V. Malven ◽  
D. F. B. Bossut ◽  
M. A. Diekman
Keyword(s):  
Breeding Season ◽  
Luteal Phase ◽  
Plasma Concentrations ◽  
Opioid Antagonist ◽  
Similar Treatment ◽  
Plasma Progesterone ◽  
Electroacupuncture Treatment

ABSTRACT Mature ewes were injected intravenously with the opioid antagonist naloxone (1·1 mg/kg) during the breeding season. Ewes with luteal phase concentrations of plasma progesterone responded with a significant (P <0·05) increase in plasma LH 14–23 min after naloxone injection. In contrast, non-luteal ewes with low plasma progesterone did not respond to injection of naloxone with an LH increase. Similar treatment of castrated males (wethers) with this dosage of naloxone failed to increase plasma LH. Electroacupuncture (EA) treatment of luteal phase ewes prevented the ability of exogenous naloxone to increase plasma LH. Treatment of wethers by EA decreased significantly (P <0·01) their high basal concentrations of plasma LH, but similar EA treatment of intact ewes did not change their low basal concentrations of LH. J. Endocr. (1984) 101, 75–80

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