scholarly journals A Comparative Study on Breast Milk Feeding and Formula Milk Feeding in Infants With Congenital Heart Disease After Surgery: A Retrospective Study

2020 ◽  
Vol 23 (6) ◽  
pp. E845-E849
Author(s):  
Xian-rong Yu ◽  
Ning Xu ◽  
Shu-ting Huang ◽  
Ze-wei Lin ◽  
Zeng-chun Wang ◽  
...  

Objective: To explore the effects of breast milk feeding and formula milk feeding on infants after cardiac surgery in the cardiac intensive care unit (ICU). Methods: Infants who underwent cardiac surgery in our ICU were divided into two groups, according to feeding type. Breast milk feeding and formula milk feeding were separately implemented in the two groups, and the remaining treatment regimens were the same. The related clinical data and feeding effects were recorded and compared. Results: The prealbumin (147.3 ± 15.2 versus 121.5 ± 18.3mg/L) and albumin (46.4 ± 4.2 versus 40.5 ± 5.1 g/L) levels in the breast milk feeding group were better than those in the formula milk feeding group (P < .05). Infants in the breast milk feeding group achieved a better total enteral nutrition time (3.0 ± 1.2 versus 5.2 ± 2.1 d), average daily weight gain (19.0 ± 3.4 versus 14.4 ± 2.3 g/kg·d), length of ICU stay (6.0 ± 2.2 versus 8.1 ± 2.9 d) and length of hospital stay (13.9 ± 4.2 versus 17.8 ± 5.6 d) than those in the formula milk feeding group (P < .05). The incidence of complications such as feeding intolerance, anemia, dyspeptic diarrhea, and nosocomial infection was lower in the breast milk feeding group than in the formula milk feeding group (P < 0.05). Conclusion: Breast milk feeding has a definite nutritional effect on infants after cardiac surgery. It is better than formula milk feeding, making it worthy of popularization and application.


Author(s):  
Ara Cho ◽  
Dayoung Ko ◽  
JoongKee Youn ◽  
Hee-Beom Yang ◽  
Hyun-Young Kim

Background: Necrotizing enterocolitis (NEC) is one of the leading causes of death in newborns, however, little is understood of which patients can be treated medically or require surgery. The purpose of our study is to analyze the associated factors of surgically treated patients compared to patients requiring only medical treatment. Methods: Patients diagnosed with necrotizing enterocolitis over a period of 14 years in a single children&rsquo;s hospital were retrospectively enrolled. Demographics and clinical data patients were collected and analyzed. Results: A total of 189 patients with NEC were included. Surgically treated patients had a lower gestational age (P = .018), body weight at birth (P = .034), and percentage of exclusive breast milk feeding (P= .001). They had increased comorbidity with respiratory distress syndrome (RDS) (P = .005), number of days of antibiotic use (P = .014), and length of hospital stay (P = .000). In multivariate logistic analysis, a lower percentage of exclusive breast milk feeding (OR = 0.366, 95% CI: 0.164-0.817) and a longer hospital stay (OR = 1.010, 95% CI: 1.001- 1.019) was associated with surgical NEC. Conclusion: Comparing medical and surgical NEC, a significantly lower percentage of surgical NEC patients were exclusively fed breast milk and their hospital stays were longer.





Chemosphere ◽  
2007 ◽  
Vol 66 (2) ◽  
pp. 311-319 ◽  
Author(s):  
Jing-Fang Hsu ◽  
Yueliang Leon Guo ◽  
Chun-Hu Liu ◽  
Shu-Chuan Hu ◽  
Jieh-Neng Wang ◽  
...  


2019 ◽  
Vol 8 (3) ◽  
pp. 295-306 ◽  
Author(s):  
Mimi Phan ◽  
Shabnam R. Momin ◽  
Mackenzie K. Senn ◽  
Alexis C. Wood


Biomedika ◽  
2012 ◽  
Vol 4 (2) ◽  
Author(s):  
Putri Rahmitasari ◽  
Burhannudin Ichsan ◽  
Sahilah Ermawati

The main indicator of public health’s degree is infant mortility rate (IMR). One of the main things that cause infant mortility is diarrhea. The existence of diarrhea’s incidence in infants can be caused due to errors in the form of food other than breast milk feeding at the age of 4 months or the practise of infant feeding with formula milk (replacement feeding). This research was an observational analytic research with cross sectional approach. Samples obtained amounted to 80 respondents who are infants aged 2-4 months in various “posyandu” in the area of Central Klaten. This sample had fulfiilled the predetermined criteria. The research instrument used a questionnaire. for the result, there were 21 respondents of 80 respondents obtained who had diarrhea. Respondents of exclusive breastfeeding who had frequency of diarrhea is rarely as many as 5 babies, whereas 1 baby for often category. Respondents of infant formula who had frequency of diarrhea is rarely as many as 12 babies, whereas 3 babies for often category. There were significant differences between infants who were breastfed exclusively with formula-fed infants againts diarrhea frequency indicated by the value of p = 0,032.Keywords: Frequency of Diarrhea, Exclusive Breast Feeding, Formula Feeding Infant, Infants Aged 2-4 Months



2013 ◽  
Vol 57 (3) ◽  
pp. 383-388 ◽  
Author(s):  
Sakil Kulkarni ◽  
Velma Mercado ◽  
Mirta Rios ◽  
Richard Arboleda ◽  
Roberto Gomara ◽  
...  


Author(s):  
Suvarna Rai

Background: Expressed breast milk is a healthy feeding option as compared to formula milk for working postnatal mothers. Objective of present work was to study the knowledge, attitude and practice regarding expressed breast milk feeding among working postnatal mothers and to identify and explore the barriers against it.Methods: A double blinded cross sectional study was conducted at a tertiary care centre in Hyderabad city, India. 100 working breastfeeding postnatal mothers with infants upto 1 year were identified. A validated questionnaire in English and Hindi was used for data collection. It constituted personal characteristics, knowledge regarding expressed breast milk feeding, attitude towards it and presently followed practices by working mothers.Results: A total of 100 working mothers with infants less than one year were selected who attended the postnatal clinics at our hospital, a tertiary care centre in Hyderabad city. Overall, the knowledge regarding expressed breast milk feeding was unsatisfactory in 64% of women. Only 36% of them had satisfactory knowledge. Positive attitude towards expressed breast milk feeding was seen in 60% of them and 40% of them had negative attitude. Expressed breast milk feeding was practised by 11% of them, formula milk by 53%, mixed feeding by 10% and cow milk by 26% as a substitute to breast feeding in their absence. Univariate analysis revealed no statistically significant determinant of their knowledge, attitude and practices.Conclusions: Knowledge about expressed breast milk feeding in Indian working breastfeeding mothers is suboptimal. Imparting adequate knowledge can improve feeding practices.



Children ◽  
2021 ◽  
Vol 8 (12) ◽  
pp. 1148
Author(s):  
Ara Cho ◽  
Dayoung Ko ◽  
JoongKee Youn ◽  
Hee-Beom Yang ◽  
Hyun-Young Kim

(1) Background: Necrotizing enterocolitis (NEC) is one of the leading causes of death in newborns despite improvements in the care of critically ill neonates. Approximately 50–70% of the cases are managed by medical therapy. However, the remaining patients require surgical intervention. The purpose of our study was to analyze the factors associated with patients requiring surgical treatment compared to patients requiring only medical treatment; (2) Method: Patients diagnosed with necrotizing enterocolitis over a period of 14 years (January 2003–December 2016) in a single tertiary referral children’s hospital were retrospectively enrolled. Demographics and clinical data were collected through the medical record and were analyzed using Pearson’s χ2 test, t-tests, and linear regression; (3) Results: A total of 189 NEC patients were analyzed. In the surgical NEC group, gestational age was lower (p = 0.018), body weight at birth was lower (p = 0.034), comorbidity with respiratory distress syndrome (RDS) was higher (p = 0.005), the days of antibiotic use were greater (p = 0.014), the percentage of breast milk feeding was lower (p = 0.001), and the length of hospital stay was longer (p < 0.000). The in-hospital mortality between the two groups was not significantly different (p = 0.196). In multivariate logistic analysis, breast milk feeding remained less associated with surgical NEC (OR = 0.366, 95% CI: 0.164–0.817), whereas the length of hospital stay was more associated with surgical NEC (OR = 1.010, 95% CI: 1.001–1.019); (4) Conclusion: Comparing medical and surgical NEC, a significantly lower percentage of surgical NEC patients were fed breast milk and their hospital stays were longer.



Author(s):  
Flaminia Bardanzellu ◽  
Alessandra Reali ◽  
Maria Antonietta Marcialis ◽  
Vassilios Fanos

Introduction: Breast Milk (BM), containing nutrients and bioactive components, represents the best source for neonatal nutrition and determines short- and long- term benefits. Human milk oligosaccharides (HMOs) play an active role in these pathophysiological mechanisms. In fact; they influence the shaping of breastfed infant’s gut microbiota, promote intestinal development, confer protection against intestinal or systemic infections modulating immune system; moreover, HMOs determine extra-intestinal effects on several target organs, i.e reducing necrotizing enterocolitis rate or improving brain development. Aims: In this review, we analyze the great inter- and intra-individual variability of BM HMOs, investigating maternal, genetic and environmental factors modulating their composition. Moreover, we provide an update regarding HMOs’ unique properties, underlining their complex interaction with intestinal microbiota and host-derived metabolites. The possible HMOs’ influence on extra-intestinal bacterial communities, potentially influencing newborns’ and even lactating mothers’ health, have been hypothesized. Finally, recognized HMOs’ crucial role, we underline the promising opportunities showed by their addition in formula milk, useful to create dairy products more similar to maternal milk itself.



Perfusion ◽  
2021 ◽  
pp. 026765912110148
Author(s):  
Joseph Mc Loughlin ◽  
Lorraine Browne ◽  
John Hinchion

Objectives: Cardiac surgery using cardiopulmonary bypass frequently provokes a systemic inflammatory response syndrome. This can lead to the development of low cardiac output syndrome (LCOS). Both of these can affect morbidity and mortality. This study is a systematic review of the impact of gaseous nitric oxide (gNO), delivered via the cardiopulmonary bypass (CPB) circuit during cardiac surgery, on post-operative outcomes. It aims to summarise the evidence available, to assess the effectiveness of gNO via the CPB circuit on outcomes, and highlight areas of further research needed to develop this hypothesis. Methods: A comprehensive search of Pubmed, Embase, Web of Science and the Cochrane Library was performed in May 2020. Only randomised control trials (RCTs) were considered. Results: Three studies were identified with a total of 274 patients. There was variation in the outcomes measures used across the studies. These studies demonstrate there is evidence that this intervention may contribute towards cardioprotection. Significant reductions in cardiac troponin I (cTnI) levels and lower vasoactive inotrope scores were seen in intervention groups. A high degree of heterogeneity between the studies exists. Meta-analysis of the duration of mechanical ventilation, length of ICU stay and length of hospital stay showed no significant differences. Conclusion: This systematic review explored the findings of three pilot RCTs. Overall the hypothesis that NO delivered via the CPB circuit can provide cardioprotection has been supported by this study. There remains a significant gap in the evidence, further high-quality research is required in both the adult and paediatric populations.



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