scholarly journals Large-Scale Survey of Cytosine Methylation of Retrotransposons and the Impact of Readout Transcription From Long Terminal Repeats on Expression of Adjacent Rice Genes

Genetics ◽  
2007 ◽  
Vol 177 (4) ◽  
pp. 1975-1985 ◽  
Author(s):  
Khalil Kashkush ◽  
Vadim Khasdan
Keyword(s):  
Large Scale ◽  
Cytosine Methylation ◽  
Long Terminal Repeats ◽  
Large Scale Survey ◽  
Terminal Repeats ◽  
The Impact

The Impact of Extraversion and Sensation Seeking on Tourist Role

2015 ◽  
Vol 43 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Cheng-Yu Li ◽  
Shiao-Yuan Lu ◽  
Bi-Kun Tsai ◽  
Keh-Yuan Yu
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Sensation Seeking ◽  
Large Scale ◽  
Personality Variables ◽  
Tourism Marketing ◽  
Large Scale Survey ◽  
And Behaviors ◽  
The Impact

In recent years, personality variables, such as extraversion and sensation seeking, have been used to investigate tourist preferences and behaviors. For this study, we classified tourist roles into three types: the familiarized mass tourist, the organized mass tourist, and the independent tourist. We investigated the impact of extraversion and sensation seeking on tourist roles in a large-scale survey of Taiwanese citizens (N = 1,249) aged 20 years and older. Using logistic regression analysis, the results indicated that sensation seeking was a significant predictor of tourist role, but extraversion was not. Compared to familiarized mass tourists, people who are sensation-seeking are more likely to become independent tourists rather than organized mass tourists. We provide suggestions for tourism marketing.

scholarly journals Spontaneous HTLV-1 transcription is accompanied by distinct epigenetic changes in the 5′ and 3′ long terminal repeats

2018 ◽  
Vol 3 ◽  
pp. 105 ◽  
Author(s):  
Michi Miura ◽  
Paola Miyazato ◽  
Yorifumi Satou ◽  
Yuetsu Tanaka ◽  
Charles R.M. Bangham
Keyword(s):  
Histone Modifications ◽  
Insertion Site ◽  
Rapid Change ◽  
Epigenetic Modifications ◽  
The Body ◽  
Ctcf Binding ◽  
Ctcf Binding Site ◽  
Long Terminal Repeats ◽  
Terminal Repeats ◽  
The Impact

Background:The human retrovirus HTLV-1 inserts the viral complementary DNA of 9 kb into the host genome. Both plus- and minus-strands of the provirus are transcribed, respectively from the 5′ and 3′ long terminal repeats (LTR). Plus-strand expression is rapid and intense once activated, whereas the minus-strand is transcribed at a lower, more constant level. To identify how HTLV-1 transcription is regulated, we investigated the epigenetic modifications associated with the onset of spontaneous plus-strand expression and the potential impact of the host factor CTCF.Methods:Patient-derived peripheral blood mononuclear cells (PBMCs) and in vitro HTLV-1-infected T cell clones were examined. Cells were stained for the plus-strand-encoded viral protein Tax, and sorted into Tax+and Tax–populations. Chromatin immunoprecipitation and methylated DNA immunoprecipitation were performed to identify epigenetic modifications in the provirus. Bisulfite-treated DNA fragments from the HTLV-1 LTRs were sequenced. Single-molecule RNA-FISH was performed, targeting HTLV-1 transcripts, for the estimation of transcription kinetics. The CRISPR/Cas9 technique was applied to alter the CTCF-binding site in the provirus, to test the impact of CTCF on the epigenetic modifications.Results:Changes in the histone modifications H3K4me3, H3K9Ac and H3K27Ac were strongly correlated with plus-strand expression. DNA in the body of the provirus was largely methylated except for the pX and 3′ LTR regions, regardless of Tax expression. The plus-strand promoter was hypomethylated when Tax was expressed. Removal of CTCF had no discernible impact on the viral transcription or epigenetic modifications.Conclusions:The histone modifications H3K4me3, H3K9Ac and H3K27Ac are highly dynamic in the HTLV-1 provirus: they show rapid change with the onset of Tax expression, and are reversible. The HTLV-1 provirus has an intrinsic pattern of epigenetic modifications that is independent of both the provirus insertion site and the chromatin architectural protein CTCF which binds to the HTLV-1 provirus.

Privacy Factors for Successful Ubiquitous Computing

2010 ◽  
pp. 1408-1424
Author(s):  
Linda Little ◽  
Pam Briggs
Keyword(s):  
Ubiquitous Computing ◽  
Detailed Analysis ◽  
Social Engagement ◽  
Large Scale ◽  
New Technologies ◽  
Cost Benefit Analysis ◽  
Cost Benefit ◽  
Human Values ◽  
Large Scale Survey ◽  
The Impact

Certain privacy principles have been established by industry, (e.g. USCAM, 2006). Over the past two years, we have been trying to understand whether such principles reflect the concerns of the ordinary citizen. We have developed a method of enquiry which displays a rich context to the user in order to elicit more detailed information about those privacy factors that underpin our acceptance of ubiquitous computing. To investigate use and acceptance Videotaped Activity Scenarios specifically related to the exchange of health, financial, shopping and e-voting information and a large scale survey were used. We present a detailed analysis of user concerns firstly in terms of a set of constructs that might reflect user-generated privacy principles; secondly those factors likely to play a key role in an individual’s cost-benefit analysis and thirdly, longer-term concerns of the citizen in terms of the impact of new technologies on social engagement and human values.

scholarly journals The impact of the economic crisis on mental health in Italy: results from a large-scale survey

2015 ◽  
Vol 25 (suppl_3) ◽  
Author(s):  
A Odone ◽  
A Migliardi ◽  
T Landriscina ◽  
L Gargiulo ◽  
G Costa
Keyword(s):  
Mental Health ◽  
Economic Crisis ◽  
Large Scale ◽  
Large Scale Survey ◽  
The Impact

Impact of Extraversion and Sensation Seeking on International Tourism Choices

2013 ◽  
Vol 41 (2) ◽  
pp. 327-333 ◽  
Author(s):  
Cheng-Yu Li ◽  
Bi-Kun Tsai
Keyword(s):  
Sensation Seeking ◽  
Large Scale ◽  
Social Activity ◽  
International Tourism ◽  
Tourism Experience ◽  
Large Scale Survey ◽  
Tourism Destinations ◽  
The Impact

Tourism is a leisure-related social activity. People always choose their desired tourism destinations and types according to their interests, intentions, and preferences. This means that personality influences tourism consumers' behavior. We examined the impact of extraversion and sensation seeking on international tourism choices, based on data obtained from a large-scale survey of Taiwanese nationals aged 20 years and older. The results of our analysis confirmed the research hypotheses, that when compared to people with no international tourism experience, those with international tourism experience tend to have higher levels of extraversion and sensation seeking.

The German Integration Panel: how to measure the influence of integration courses on migrants integration?

2014 ◽  
Vol 7 (1) ◽  
pp. 43-55
Author(s):  
Nina Rother
Keyword(s):  
Language Proficiency ◽  
Large Scale ◽  
Language Skills ◽  
German Society ◽  
German Language ◽  
Control Group ◽  
Key Issues ◽  
Large Scale Survey ◽  
The Right ◽  
The Impact

In 2005, Germany’s Federal Government introduced integration courses in order to enable migrants to improve their German language skills and thereby also their general integration into German society. From 2005 to 2007, about 500,000 migrants were granted the right to take part in an integration course. Several methodological challenges had to be overcome when establishing the German Integration Panel, a longitudinal survey aimed at analysing the efficiency and sustainability of integration courses and the impact they have on general integration processes. Among the key issues of this large-scale survey was its global design, especially the composition and accessibility of a control group of non-course participants as well as the assessment of German language proficiency. 

scholarly journals The impact of journal re-grading on perception of ranking systems: Exploring the case of the Academic Journal Guide and Business and Management scholars in the UK

2019 ◽  
Vol 28 (3) ◽  
pp. 218-231 ◽  
Author(s):  
James T Walker ◽  
Ammon Salter ◽  
Rita Fontinha ◽  
Rossella Salandra
Keyword(s):  
Large Scale ◽  
Academic Research ◽  
Academic Journal ◽  
Working Lives ◽  
Ranking Systems ◽  
Large Scale Survey ◽  
Using Data ◽  
The Uk ◽  
The Impact ◽  
Business And Management

Abstract The marked increase in the use of metrics, such as journal lists, to assess research has had a profound effect on academics’ working lives. While some view the diffusion of rankings as beneficial, others consider their diffusion as a malicious development, which further acerbates a tendency towards managerialism in academia, and undermine the integrity and diversity of academic research. Using data from a large-scale survey and a re-grading of journals in a ranking used by Business and Management UK scholars—the Academic Journal Guide—as a pseudo-experiment, we examine what determines negative and positive perceptions of rankings. We find that the individuals who published in outlets that were upgraded were less hostile to the ranking than those who did not benefit from these changes, and that individuals were also less hostile to the ranking if outlets in their field had benefited from re-grading in the new list. We also find that the individuals who published in outlets that were upgraded were more positive to the ranking than those who did not benefit from these changes, and that individuals were also more positive to the ranking if outlets in their field had benefited from re-grading in the new list.

Does cultural capital matter for individual job performance? A large-scale survey of the impact of cultural, social and psychological capital on individual performance in Brazil

2018 ◽  
Vol 67 (8) ◽  
pp. 1352-1370 ◽  
Author(s):  
Adailson Soares Santos ◽  
Mário Teixeira Reis Neto ◽  
Ernst Verwaal
Keyword(s):  
Factor Analysis ◽  
Job Performance ◽  
Cultural Capital ◽  
Large Scale ◽  
Psychological Capital ◽  
Individual Performance ◽  
Research Approach ◽  
Content Type ◽  
Large Scale Survey ◽  
The Impact

Purpose The purpose of this paper is to analyze the effect of cultural, social and psychological capital on the individual job performance. The authors propose and empirically test a combination of models, which originate from sociology and positive psychology, and demonstrate that cultural capital – in addition to social and psychological capital – is an important driver of individual job performance. Design/methodology/approach The paper opted for a large-scale survey research design. The sample consists of employees in several occupations who had formal contracts with companies from the public and private sector in Brazil. The measurement instrument is developed and tested by using data collected among 369 valid respondents in 2016. The methods applied include exploratory factor analysis and confirmatory factor analysis through partial least squares estimation. Findings The results obtained indicate that there is a significant simultaneous positive effect of cultural, social and psychological capital on individual job performance. The results indicate that cultural, psychological and social capitals together were able to explain 57 percent of the respondents’ individual job performance, with psychological capital being the dominant driver. The authors also find that cultural capital is at least as important as driver of individual job performance as social capital. Research limitations/implications Because of the chosen research approach, the research results may have limited generalizability and may suffer from potential bias in terms of social desirability. Therefore, researchers are encouraged to test the propositions in different country contexts using different research methods. Originality/value This paper is the first to quantify the relevance of Bourdieu’s cultural capital theory to the study of individual job performance, and offers tools with validated psychometric properties for its empirical assessment.

Privacy Factors for Successful Ubiquitous Computing

2011 ◽  
pp. 143-160
Author(s):  
Linda Little ◽  
Pam Briggs
Keyword(s):  
Ubiquitous Computing ◽  
Social Engagement ◽  
Large Scale ◽  
New Technologies ◽  
Cost Benefit Analysis ◽  
Cost Benefit ◽  
Computing Machinery ◽  
Large Scale Survey ◽  
The Impact ◽  
The U.S

Certain privacy principles have been established by industry, e.g. the U.S. Public Policy Committee of the Association for Computing Machinery (USACM). Over the past two years, we have been trying to understand whether such principles reflect the concerns of the ordinary citizen. We have developed a method of enquiry which displays a rich context to the user in order to elicit more detailed information about those privacy factors that underpin our acceptance of ubiquitous computing. To investigate use and acceptance, Videotaped Activity Scenarios specifically related to the exchange of health, financial, shopping and e-voting information and a large scale survey were used. We present a detailed analysis of user concerns, firstly in terms of a modified Hertzberg model that identifies a set of constructs that might reflect user-generated privacy principles, secondly those factors likely to play a key role in an individuals cost-benefit analysis, and thirdly, longer-term concerns of the citizen in terms of the impact of new technologies on social engagement and human values.

scholarly journals Are the poor benefiting from China's land conservation program?

2007 ◽  
Vol 12 (4) ◽  
pp. 593-620 ◽  
Author(s):  
EMI UCHIDA ◽  
JINTAO XU ◽  
ZHIGANG XU ◽  
SCOTT ROZELLE
Keyword(s):  
Rural Areas ◽  
Poverty Alleviation ◽  
Large Scale ◽  
Land Conservation ◽  
Grain For Green ◽  
The Poor ◽  
Weak Evidence ◽  
Program Effects ◽  
Large Scale Survey ◽  
The Impact

This paper studies the impact of the largest conservation set-aside program in the developing world: China's Grain for Green program, on poverty alleviation in rural areas. Based on a large-scale survey, we find that the program was implemented mostly in the areas of China that are fairly poor. In addition, we show that income from livestock activities and some types of asset holdings of participants have increased significantly more than those of non-participants (due to program effects). Only weak evidence is provided demonstrating that participating households have begun to shift their labor into the off-farm sectors. Overall, the results suggest that the program has been moderately successful in achieving its poverty alleviation objectives.

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