scholarly journals The long term effects of outdoor air pollution in urban environments on cardiovascular health: a global review

CommonHealth ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 122-133
Author(s):  
Lindsay Kraus ◽  
Heather Murphy

The effect of air pollution on health is listed as a significant cause of death worldwide. Slightly over 3 million deaths per year are due to outdoor air pollution. Studies have shown that short term increases in exposure to particulate matter have increased the risk of cardiovascular diseases such as myocardial infarction, stroke, and heart failure. However, less is known about the longer term effects of air pollution on various cardiovascular diseases. The American Heart Association formally recognized PM2.5 as a significant cardiovascular risk factor in 2010. Since then, more prolonged term exposure to air pollution has been suggested to cause chronic cardiometabolic and cardiovascular problems. The effects of long term (>3 years) air pollution are significant, but not as much is known about how location affects this exposure. Associations with cardiovascular diseases and their risk factors are often increased in urban settings, which is attributed to a higher concentrations of outdoor air pollution, independent of ethnic groups and seasonal changes. Potential causes of long term air pollution concentrations in cities or metropolitan areas come from traffic exposure and traffic intensity. The Environmental Protection Agency and United Nations have suggested changes in air quality standards, implementation plans, and ways to reduce vehicle emissions specifically to improve human health and reduce the adverse effects of air pollution; however, more work still needs to be done. This review assesses the impact of the global long term (>3 years) air pollution exposure, specifically in urban environments on cardiovascular health and disease.

Epidemiology ◽  
2013 ◽  
Vol 24 (1) ◽  
pp. 44-53 ◽  
Author(s):  
Richard W. Atkinson ◽  
Iain M. Carey ◽  
Andrew J. Kent ◽  
Tjeerd P. van Staa ◽  
H. Ross Anderson ◽  
...  

2019 ◽  
Vol 129 ◽  
pp. 28-34 ◽  
Author(s):  
Rosario Toro ◽  
George S. Downward ◽  
Marianne van der Mark ◽  
Maartje Brouwer ◽  
Anke Huss ◽  
...  

2008 ◽  
Vol 115 (6) ◽  
pp. 175-187 ◽  
Author(s):  
Robert D. Brook

Air pollution is a heterogeneous mixture of gases, liquids and PM (particulate matter). In the modern urban world, PM is principally derived from fossil fuel combustion with individual constituents varying in size from a few nanometres to 10 μm in diameter. In addition to the ambient concentration, the pollution source and chemical composition may play roles in determining the biological toxicity and subsequent health effects. Nevertheless, studies from across the world have consistently shown that both short- and long-term exposures to PM are associated with a host of cardiovascular diseases, including myocardial ischaemia and infarctions, heart failure, arrhythmias, strokes and increased cardiovascular mortality. Evidence from cellular/toxicological experiments, controlled animal and human exposures and human panel studies have demonstrated several mechanisms by which particle exposure may both trigger acute events as well as prompt the chronic development of cardiovascular diseases. PM inhaled into the pulmonary tree may instigate remote cardiovascular health effects via three general pathways: instigation of systemic inflammation and/or oxidative stress, alterations in autonomic balance, and potentially by direct actions upon the vasculature of particle constituents capable of reaching the systemic circulation. In turn, these responses have been shown to trigger acute arterial vasoconstriction, endothelial dysfunction, arrhythmias and pro-coagulant/thrombotic actions. Finally, long-term exposure has been shown to enhance the chronic genesis of atherosclerosis. Although the risk to one individual at any single time point is small, given the prodigious number of people continuously exposed, PM air pollution imparts a tremendous burden to the global public health, ranking it as the 13th leading cause of morality (approx. 800000 annual deaths).


2007 ◽  
Vol 41 (7) ◽  
pp. 1343-1358 ◽  
Author(s):  
Rob Beelen ◽  
Gerard Hoek ◽  
Paul Fischer ◽  
Piet A van den Brandt ◽  
Bert Brunekreef

2014 ◽  
Vol 2014 (1) ◽  
pp. 2680 ◽  
Author(s):  
Gloria Chi* ◽  
Yongmei Liu ◽  
James MacDonald ◽  
R. Graham Barr ◽  
Kathleen Donohue ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document