Study of Incidence of Hepatitis B and A Comparative Study to Check the Specificity & Sensitivity of Immunochromatographic Technique (ICT with Enzyme Linked Immunosorbant Assay (ELISA) for Hepatitis B Infection

2012 ◽  
Vol 2 (4) ◽  
pp. 31-33
Author(s):  
Swati Tomar ◽  
◽  
Prathmesh Chourey ◽  
Dr. A. D. Urhekar Dr. A. D. Urhekar ◽  
Asha Kore
2006 ◽  
Vol 13 (04) ◽  
pp. 632-636
Author(s):  
MOHAMMAD FAYYAZ ◽  
Muhammad Ayub Khan ◽  
MASROOR ALI QAZI ◽  
Ghulam Mohyud Din `Chaudhary ◽  
GULZAR AHMED

Objective: To determine the prevalence of HBV, HCV and HIV in healthyblood donors in Blood Transfusion Services, Bahawal Victoria Hospital, Bahawalpur. Design: Prospective observationalstudy. Setting: Blood Transfusion Services, Bahawal Victoria Hospital (BVH), affiliated with Quaid-e-Azam medicalCollege Bahawalpur. Period: From 1 January t st o 31st December 2005. Methods and Materials: All the personscoming for blood donations , at the BVH facility, were included. Clinically anaemic, ill, past history of jaundice and ageof less than 18 or more than 50 years were excluded. All the donors (27938) from various areas of Bahawalpur,Bahawalnagar, Lodhran, Vehari and Rahim Yar Khan districts, were screened for hepatitis B surface antigen (HBs)Antigen, hepatitis C antibody (Anti HCV) & Human Immuno-deficiency Virus Antibody (Anti-HIV)on sera by one StepTest Device. All the positives cases were confirmed by Enzyme Linked Immunosorbant Assay. Results: Out of total27938, 25420(91%) were male. Mean age was 28 years with age range 18-50. No HIV positive case was detected.HBV was 2.69%, slightly more than HCV, 2.52%. Males were significantly (p<0.02) more infected than females.Conclusion: Risk of transmission of viral hepatitis is a major problem of blood transfusion. Frequency of viral hepatitisin blood donors is higher in our area as compared to rest of the world. HIV infection is very low. Preventive strategiesinclude good blood transfusion services along with safe sex and other measures.


Author(s):  
Marupuri Sushma ◽  
M. A. Musthaq Pasha ◽  
Afsar Fatima ◽  
B. Issac Ebenezer

Background: Hepatitis B is a major health problem worldwide and more serious in India. An estimated 240 million people are chronically infected with hepatitis B. Hepatitis B is an important occupational hazard for health workers. However, it can be prevented by currently available safe and effective vaccine. A Study on Awareness of Hepatitis B Infection and Vaccination among Medical Interns and Nursing interns in Santhiram Medical College, Nandyal, Kurnool, Andhra Pradesh.Methods: A cross-sectional comparative study is done. Students who are present at the time of data collection by a pre structured pre-tested questionnaire given. Data was analyzed by usingSPSS 21 version. Data was presented in proportions and chi-square was done for significance with 95% confidence interval.Results: The study was under taken among the medical interns (80) and nursing interns (70) at Santhiram Medical College, Nandyal. Out of all 150 students 87% all know that the type of infections viral. There is a significant knowledge difference between the medical interns and nursing interns about the knowledge of the modes of transmission i.e. Medical interns have higher knowledge when compared to nursing interns. 97% of medical interns are vaccinated whereas only 50% of nursing interns and also significant difference knowledge about the post exposure prophylaxis 76% in medical interns 19% in nursing interns.Conclusions: This study showed that overall awareness regarding hepatitis B is at a very basic level among the nursing interns when compared to medical interns of the future and measures need to be taken to create complete awareness. 


2016 ◽  
Vol 8 ◽  
pp. e2016046 ◽  
Author(s):  
Widad Yazaji ◽  
Wafa Habbal ◽  
Fawza Monem

Background and objectives: Blood transfusion is a lifesaving therapy for patients with hemoglobinopathies. However, the need of frequent transfusion carries the risk of transmitting hepatitis B and C infections which are intermediately prevalent in Syria. Despite screening blood donations with sensitive methods, the risk of transmission is still present when infectious blood is donated within the window period. This study aimed to investigate the incidence of HBV and HCV seropositivity, and its association with multiple transfusions among Syrian hemoglobinopathies patients.Materials and Methods: HBsAg, anti-HBc, anti-HBs and anti-HCV were tested for 159 Syrian multitransfused patients by Enzyme Linked Immunosorbant Assay (ELISA).Results: Thirty-nine of 159 (24.5%) multitransfused patients were HBsAg/anti-HBc or anti-HCV positive, 26 (16%) of which never visited the dentist, and they either tested postsurgically negative for HBsAg and anti-HCV or never underwent a surgical procedure. On the contrary of anti-HCV seropositivity, HBsAg/anti-HBc seropositivity was significantly associated with the number of blood transfusions, number of blood units and age (P < 0.001).Conclusion: About one-sixth of our patients most likely acquired HBV/HCV infection via blood transfusion. Administering HBV vaccine, ensuring the immune status, and monitoring hepatitis markers might considerably minimize the incidence of viral hepatitis among multitransfused patients.


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