scholarly journals Susceptibilidad a antimicrobianos de patógenos respiratorios en niños provenientes de la comunidad

2013 ◽  
Vol 65 (1) ◽  
pp. 14
Author(s):  
José M Guevara ◽  
Rosaluz Aróstegui ◽  
Wini Agurto ◽  
Iliana Sobrevilla ◽  
Esther Valencia ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Streptococcus Pyogenes ◽  
Moraxella Catarrhalis

OBJETIVO: Determinar la resistencia de los patógenos respiratorios a diferentes antimicrobianos. MATERIAL Y MÉTODOS: Entre abril y noviembre de 2002 se estudió 177 pacientes que asistieron al consultorio externo de otorrinolaringología del Hospital Nacional Docente Madre-Niño San Bartolomé. RESULTADOS: Streptococcus pneumoniae fue la bacteria patógena más aislada (57,2%), luego Moraxella catarrhalis (42,7%), Staphylococcus aureus (18,6%) y en pequeña cantidad Haemophilus influenzae (3,4%) y Streptococcus pyogenes (0,7%). Streptococcus pneumoniae presentó 31,3% de resistencia a la penicilina. El 96,7% de Moraxella catarrhalis fueron productoras de betalactamasa y 7,4% de los Staphylococcus aureus fueron resistentes a la oxacilina. CONCLUSIÓN: Streptococcus pneumoniae es el principal agente causal de los procesos infecciosos altos en niños y su resistencia a la penicilina aumentó a 31,3%

scholarly journals Determination of antimicrobial action of "Apicold oral spray"

2021 ◽  
pp. 66-70
Author(s):  
Anatoly L. Kosakovsky ◽  
Oksana M. Golovnya ◽  
Svitlana G. Gunko ◽  
Ilona A. Kosakivska
Keyword(s):  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Streptococcus Pyogenes ◽  
Moraxella Catarrhalis ◽  
Antimicrobial Effect ◽  
Antimicrobial Action ◽  
Clinical Isolates ◽  
Fungicidal Action

Introduction: The causative agents of acute tonsillopharyngitis are viruses and bacterial flora. Treatment of acute pharyngitis is mainly local, which includes aerosols with antiseptics. Aim: Study of antimicrobial action of "Apicold oral spray" on clinical isolates of microorganisms Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis and Candida albicans isolated from patients' oropharynx in patients. Material and methods: The effect of Apicold Oral Spray (manufactured by APIPHARMA doo) on clinical isolates of Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis, and Candida albicans in Ukrainian patients was studied. Antimicrobial activity was assessed after 5, 10 and 20 minutes of action of one dose of "Apicold oral spray" on microorganisms. Bactericidal and fungicidal action (inhibition of cell growth of microorganisms) is expressed as a percentage according to the control. Results and discussion: Apicold Oral Spray has a 100% antimicrobial effect after 5 minutes on clinical isolates of Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis and Candida albicans (complete growth inhibition of all 5 clinical isolates after 20 minutes). Conclusion: "Apicold oral spray" has a high antimicrobial effect on clinical isolates of Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis and Candida albicans, which is confirmed by 100% inhibition of the growth of all bacteria after 5 minutes

scholarly journals Επίδραση των ιογενών λοιμώξεων του αναπνευστικού στο βακτηριακό αποικισμό του ρινοφάρυγγα σε παιδιά

2017 ◽  
Author(s):  
Παρασκευή Τσιάλτα
Keyword(s):  
Staphylococcus Aureus ◽  
Polymerase Chain Reaction ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Streptococcus Pyogenes ◽  
Reverse Transcription ◽  
Moraxella Catarrhalis ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Polymerase Chain

Εισαγωγή: Ο αποικισμός του ρινοφάρυγγα από βακτήρια προηγείται της εκδήλωσης βακτηριακών λοιμώξεων του ανώτερου και κατώτερου αναπνευστικού συστήματος αλλά και διεισδυτικών. Σκοπός της μελέτης είναι να διερευνήσει τη συχνότητα του βακτηριακού αποικισμού του ρινοφάρυγγα σε παιδιά με ή χωρίς συμπτώματα οξείας ιογενούς λοίμωξης του αναπνευστικού συστήματος και να εξετάσει πιθανές συσχετίσεις μεταξύ των ταυτοποιούμενων μικροοργανισμών. Υλικό και μέθοδοι: Ελέγχθηκαν βρέφη και παιδιά ηλικίας 3 μηνών έως 5 ετών με και χωρίς συμπτώματα ιογενούς λοίμωξης του αναπνευστικού συστήματος και για κάθε παιδί που συμμετείχε στη μελέτη συμπληρώθηκε ειδικό ερωτηματολόγιο με δημογραφικά και κλινικά δεδομένα. Τα δείγματα ρινοφαρυγγικού επιχρίσματος, που λήφθηκαν με στυλεό αλγινικού ασβεστίου, εξετάστηκαν για βακτηριακό αποικισμό με Streptococcus pneumoniae (SP), Haemophilus influenzae (HI), Moraxella catarrhalis (MC), και Streptococcus pyogenes (SPyo) και τα δείγματα ρινικού επιχρίσματος, που λήφθηκαν με βαμβακοφόρο στυλεό, από τις πρόσθιες ρινικές θαλάμες εξετάστηκαν για βακτηριακό αποικισμό με Staphylococcus aureus (SA). Η παρουσία ιού της γρίπης (IFV) και της παραγρίπης (PIV), αναπνευστικού συγκυτιακού ιού (RSV), ρινοϊού (RV) και αδενοϊού (AV) εκτιμήθηκε με αλυσιδωτή αντίδραση πολυμεράσης αντίστροφης μεταγραφής (Reverse-transcription Polymerase Chain Reaction, RT-PCR). Αποτελέσματα: Στη μελέτη συμπεριλήφθησαν 386 βρέφη και παιδιά (216 αγόρια). Η μέση ηλικία των παιδιών ήταν 23,4 μήνες. Από τα 386 παιδιά, τα 127 δεν είχαν συμπτώματα από το αναπνευστικό σύστημα. Σε ένα πολύ υψηλό ποσοστό ασυμπτωματικών παιδιών δεν απομονώθηκε κανένα από τα βακτήρια που εξετάστηκαν (p<0,01). Ο S. pneumoniae (p<0,01), η M. catarrhalis (p=0,001) και οι συνδυασμοί των βακτηρίων, που εξετάστηκαν, απομονώθηκαν πιο συχνά από συμπτωματικά παιδιά (p<0,05) συγκριτικά με τα ασυμπτωματικά παιδιά. Ο αποικισμός με M. catarrhalis παιδιών,- που ήταν θετικά για ιούς,- ήταν συχνότερος σε σύγκριση με τα παιδιά, στα οποία δεν διαπιστώθηκε ιογενής λοίμωξη (p<0,05). Τα υψηλότερα ποσοστά αποικισμού με H. influenzae και M. catarrhalis παρατηρήθηκαν σε παιδιά, που ήταν θετικά για τον ιό της γρίπης. Μεταξύ των παιδιών που ήταν αποικισμένα με S. pneumoniae, ανιχνεύθηκε υψηλό ποσοστό αποικισμού και με H. influenzae. Παρατηρήθηκε αρνητική συσχέτιση μεταξύ του S. pneumoniae και του S. aureus και μια αυξημένη πιθανότητα ανίχνευσης της M. catarrhalis παρουσία του H. influenzae. Ο αποικισμός με H. influenzae ήταν συχνότερος μεταξύ των παιδιών, στα οποία είχε απομονωθεί RSV και ο αποικισμός με M. catarrhalis συσχετίστηκε με την ανίχνευση του RV. Συμπεράσματα: Οι ιογενείς λοιμώξεις του ανώτερου αναπνευστικού συστήματος επηρεάζουν τη συχνότητα αλλά και το είδος των βακτηρίων που αποικίζουν το ρινοφάρυγγα. Οι συσχετίσεις που παρατηρήθηκαν μεταξύ δυνητικά παθογόνων μικροοργανισμών ενδέχεται να παίζουν σημαντικό ρόλο στην εκδήλωση νόσου από αυτούς. Η χορήγηση των εμβολίων επηρεάζει το βακτηριακό αποικισμό του ρινοφάρυγγα και για αυτό το λόγο απαιτείται συνεχής επιδημιολογική επιτήρηση των σοβαρών διεισδυτικών λοιμώξεων.

scholarly journals The Relationship between Colonization by Moraxella catarrhalis and Tonsillar Hypertrophy

2018 ◽  
Vol 2018 ◽  
pp. 1-9
Author(s):  
Mirela C. M. Prates ◽  
Edwin Tamashiro ◽  
José L. Proenca-Modena ◽  
Miriã F. Criado ◽  
Tamara H. Saturno ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Pathogenic Bacteria ◽  
Simultaneous Detection ◽  
Tonsillar Hypertrophy ◽  
Palatine Tonsils ◽  
Adenotonsillar Hypertrophy

We sought to investigate the prevalence of potentially pathogenic bacteria in secretions and tonsillar tissues of children with chronic adenotonsillitis hypertrophy compared to controls. Prospective case-control study comparing patients between 2 and 12 years old who underwent adenotonsillectomy due to chronic adenotonsillar hypertrophy to children without disease. We compared detection of Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Pseudomonas aeruginosa, and Moraxella catarrhalis by real-time PCR in palatine tonsils, adenoids, and nasopharyngeal washes obtained from 37 children with and 14 without adenotonsillar hypertrophy. We found high frequency (>50%) of Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis, and Pseudomonas aeruginosa in both groups of patients. Although different sampling sites can be infected with more than one bacterium and some bacteria can be detected in different tissues in the same patient, adenoids, palatine tonsils, and nasopharyngeal washes were not uniformly infected by the same bacteria. Adenoids and palatine tonsils of patients with severe adenotonsillar hypertrophy had higher rates of bacterial coinfection. There was good correlation of detection of Moraxella catarrhalis in different sampling sites in patients with more severe tonsillar hypertrophy, suggesting that Moraxella catarrhalis may be associated with the development of more severe hypertrophy, that inflammatory conditions favor colonization by this agent. Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Moraxella catarrhalis are frequently detected in palatine tonsils, adenoids, and nasopharyngeal washes in children. Simultaneous detection of Moraxella catarrhalis in adenoids, palatine tonsils, and nasopharyngeal washes was correlated with more severe tonsillar hypertrophy.

scholarly journals Moraxella Catarrhalis en las Infecciones Respiratorias Altas

2014 ◽  
Vol 58 (3) ◽  
pp. 192
Author(s):  
José Guevara Duncan ◽  
Jorge Navach ◽  
Rosaluz Aróstegui ◽  
Winni Agurto ◽  
Alfredo Goytendía ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Haemophilus Influenza

Durante 12 meses se estudian las infecciones otorrinolaringológicas en dos hospitales de Lima, tanto en niños como en adultos, con especial énfasis en Moraxella catarrhalis. Se tomaron 318 muestras de igual número de pacientes, de los cuales el 40% resultó negativo a bacterias patógenas. Del 60% restante se identificó staphylococcus aureus como el causante del 31% de las infecciones, seguido de Streptococcus pneumoniae colt el 19%, hieto Moraxella catarrhalis colt 16% y en cuarto lugar Haemophilus influenzae colt 10%. Rinorrea purulenta fue el principal síntoma en todos los casos. Streptococcus pneumoniae, Moraxella catarrhalis y Haemophilus influenza se aislaron mayoritariamente en niños menores de 14 años. El 15% de los S. aureus fueron oxacilino-ressistentes, el 11% de S. pneumoniae fueron resistentes a la penicilina, el 70% de M. catarrhalis eran productoras de B-1actailiasay cl 5% de H. influenzae también producían lactamasa. Nuestros resultados permiten oriental-mayor el tratamiento antibiótico de las infecciones respiratorias altas.

scholarly journals Co-carriage of Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis among three different age categories of children in Hungary

PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0229021 ◽  
Author(s):  
Eszter Kovács ◽  
Judit Sahin-Tóth ◽  
Adrienn Tóthpál ◽  
Mark van der Linden ◽  
Tamás Tirczka ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis

scholarly journals Increased recovery of Moraxella catarrhalis and Haemophilus influenzae in association with group A β-haemolytic streptococci in healthy children and those with pharyngo-tonsillitis

2006 ◽  
Vol 55 (8) ◽  
pp. 989-992 ◽  
Author(s):  
Itzhak Brook ◽  
Alan E. Gober
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Inflammatory Process ◽  
Bacterial Species ◽  
Healthy Children ◽  
Staph Aureus ◽  
Penicillin Therapy ◽  
Group A

The inflamed tonsils harbour numerous types of bacteria, alone or in combination with group A β-haemolytic streptococci (GABHS). The cohabitation of the tonsils by GABHS and certain other bacterial species may contribute to the inflammatory process and the failure of penicillin therapy. This study evaluated the recovery of Moraxella catarrhalis, Haemophilus influenzae, Staphylococcus aureus and Streptococcus pneumoniae in association with GABHS in healthy children and those with acute pharyngo-tonsillitis (APT). Pharyngo-tonsillar cultures were obtained from 548 children with APT and 866 healthy children. GABHS was recovered from 112 (20.4 %) children with APT. Of the 114 H. influenzae isolates, 32 were recovered in association with GABHS (29 % of all patients who had GABHS) and 82 were isolated without GABHS (19 %) (P=0.0267). Of the 69 M. catarrhalis isolates, 25 were recovered in association with GABHS (22 % of all patients who had GABHS) and 44 were isolated without GABHS (10 %) (P=0.0012). In contrast, there was no association between the isolation of GABHS and the recovery of Staph. aureus or Strep. pneumoniae. GABHS was recovered from 104 (12 %) healthy children. Of the 69 M. catarrhalis isolates, 24 were recovered in association with GABHS (23 % of all patients who had GABHS) and 80 were isolated without GABHS (10 %) (P=0.006). There was no association between the isolation of GABHS and the recovery of H. influenzae, Staph. aureus or Strep. pneumoniae. This study demonstrates an association between the recovery of GABHS and H. influenzae and M. catarrhalis from pharyngo-tonsillar cultures of patients with APT and M. catarrhalis from pharyngo-tonsillar cultures of healthy children.

scholarly journals Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus isolated from the nasopharynx of healthy children attending day-care centres in the Czech Republic

2006 ◽  
Vol 134 (6) ◽  
pp. 1179-1187 ◽  
Author(s):  
H. ŽEMLIČKOVÁ ◽  
P. URBÁšKOVÁ ◽  
V. ADÁMKOVÁ ◽  
J. MOTLOVÁ ◽  
V. LEBEDOVÁ ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Day Care ◽  
Respiratory Pathogens ◽  
Healthy Children ◽  
Older Children ◽  
Age Related ◽  
Day Care Centres

Nasopharyngeal carriage of potential pathogens was studied in 425 healthy 3- to 6-year-old children attending 16 day-care centres (DCCs) in nine Czech cities during the winter 2004–2005. The overall carriage of pathogens was 62·8% (Streptococcus pneumoniae, 38·1%; Haemophilus influenzae, 24·9%; Moraxella catarrhalis, 22·1%; Staphylococcus aureus, 16%). An age-related downward trend was observed for colonization with respiratory pathogens in contrast to Staph. aureus whose carriage was significantly higher among older children. The following serotypes of colonizing S. pneumoniae were the most predominant: 23F (20·6%), 6A (15·1%), 6B (12·7%), 18C (7·8%), 15B and 19F (6% each). The majority (94·3%) of H. influenzae isolates were non-typable; among capsulated isolates, serotype b was not found. Decreased susceptibility to penicillin was determined in 3% of pneumococci; 4·6% of H. influenzae strains and 85·1% of M. catarrhalis strains produced β-lactamase. As for non-β-lactam antibiotics, pneumococci resistant to trimethoprim–sulphamethoxazole were the most common (15·7%) among the attendees.

scholarly journals In Vitro Activities of ABT-492, a New Fluoroquinolone, against 155 Aerobic and 171 Anaerobic Pathogens Isolated from Antral Sinus Puncture Specimens from Patients with Sinusitis

2003 ◽  
Vol 47 (9) ◽  
pp. 3008-3011 ◽  
Author(s):  
Ellie J. C. Goldstein ◽  
Diane M. Citron ◽  
C. Vreni Merriam ◽  
Yumi A. Warren ◽  
Kerin L. Tyrrell ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Methicillin Resistant ◽  
Resistant Strains ◽  
Aerobic And Anaerobic

ABSTRACT ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015. It was four- to sixfold more active than other fluoroquinolones, including against levofloxacin-resistant strains of S. pneumoniae, methicillin-resistant Staphylococcus aureus, and Prevotella species.

scholarly journals Activity of Faropenem against Middle Ear Fluid Pathogens from Children with Acute Otitis Media in Costa Rica and Israel

2007 ◽  
Vol 51 (6) ◽  
pp. 2230-2235 ◽  
Author(s):  
Kimberley Clawson Stone ◽  
Ron Dagan ◽  
Adriano Arguedas ◽  
Eugene Leibovitz ◽  
Elaine Wang ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Costa Rica ◽  
Haemophilus Influenzae ◽  
Otitis Media ◽  
Streptococcus Pyogenes ◽  
Middle Ear ◽  
Moraxella Catarrhalis ◽  
Acute Otitis Media ◽  
The Other ◽  
Middle Ear Fluid

ABSTRACT Faropenem was tested against 1,188 middle ear fluid pathogens from children in Israel and Costa Rica. Against Streptococcus pneumoniae and Haemophilus influenzae, faropenem was the most active β-lactam, with activity that was similar to or greater than of the other oral antimicrobial classes studied. Faropenem was also active against Moraxella catarrhalis and Streptococcus pyogenes.

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