scholarly journals Nauja skydliaukės masės ir tūrio matavimo ultragarsu metodika

2003 ◽  
Vol 1 (2) ◽  
pp. 0-0
Author(s):  
Paulius Žeromskas ◽  
Algimantas Bubnys ◽  
Kęstutis Strupas
Keyword(s):  
Thyroid Gland ◽  
Mass Measurement ◽  
Volume Measurement ◽  
New Method ◽  
Gland Volume ◽  
Gland Tissue ◽  
Thyroid Gland Volume ◽  
Mathematical Formulas ◽  
Thyroid Gland Tissue

Paulius Žeromskas, Algimantas Bubnys, Kęstutis StrupasVilniaus universiteto Pilvo chirurgijos centras,Santariškių g. 2, LT-2021 VilniusEl paštas: [email protected] Įvadas / tikslas Vilniaus universiteto Pilvo chirurgijos klinikoje parengta nauja skydliaukės masės ir tūrio matavimo metodika, pritaikoma įprastinei ultragarsinei įrangai. Metodai Metodika buvo paruošta ultragarsu (pagal pasiūlytus principus) prieš operaciją išmatavus ir po operacijos pasvėrus bei tūrį išmatavus 187 skydliaukės skilčių ir 88 sąsmaukų. Rezultatai / išvados Tirdami nustatėme, kad 1 g skydliaukės audinio tūris yra 0,958 ml ir šis skirtumas yra statistiškai patikimas. Todėl tūris ir masė turi būti skaičiuojami atskirai. Naujai metodikai parengtos skilčių ir sąsmaukos masės bei tūrio skaičiavimo formulės: Vsąs = 0,991 x A x B x C, Msąs = 1,051 x A x B x C,Vsk = 0,49 x A x B x C , Msk = 0,508 x A x B x C; čia: Vsk – skilties tūris, Msk – skilties masė, Vsąs – sąsmaukos tūris, Msąs – sasmaukos masė, A – skilties (ar sąsmaukos) aukštis, B – skilties (ar sąsmaukos) plotis, C – skilties (ar sąsmaukos ) storis. Skydliaukės tūris (masė) lygus abiejų skilčių ir sąsmaukos tūrių (masių) sumai. Metodikos tikslumą nustatėme palyginę prieš operaciją ultragarsu išmatuotą skydliaukės masę ir tūrį su pašalintos skydliaukės mase ir tūriu. Koreliacijos koeficientas buvo r = 0,97 (n = 71). Metodika parengta įprastinei ultragarsinei įrangai. Prasminiai žodžiai: endokrinologija, skydliaukės masė, skydliaukės tūris, tiroidektomija, voliumetrija. A new method of thyroid gland volume measurement by ultrasound in vivo Paulius Žeromskas, Algimantas Bubnys, Kęstutis Strupas Background / objective A new method of thyroid gland volume and mass measurement by ultrasound was elaborated at the Clinic of Abdominal Surgery of Vilnius University. Methods The method was proposed after ultrasonic pre-operative measurement (by our approach) and post-operative weighing and volume measurement of 187 thyroid lobes and 88 isthmuses. Results / conclusions We found that the volume of 1g of thyroid gland tissue is 0.958 ml and the difference is statistically significant. Thus, thyroid mass and volume must be calculated separately. To measure the size of the thyroid gland according to the new method, the following mathematical formulas are suggested: Vist = 0.991 × A × B × C, Mist = 1.051× A × B × C,Vlob = 0.49 × A × B × C, Mlob = 0.508 × A × B × C, where Vist is the isthmus volume, Mist is the isthmus weight, Vlob is the lobe volume, Mlob is the lobe weight, A is lobe (or isthmus) length, B is lobe (or isthmus) width, C is lobe (or isthmus) depth. The volume (or mass) of the thyroid gland is the sum ultrasonically determined volumes (or masses) of the both lobes and the isthmus. The accuracy of the method has been ascertained by comparing the ultrasonically determined volume (and weight) with the volume (and weight) of the same gland removed surgically. The correlation coefficient was r=0.97 (n=71). The method is adapted to ordinary ultrasound equipment. Keywords: endocrinology, thyroid gland mass, thyroid gland tissue volume, thyroidectomy, volumetry

Compensated 131I-therapy of solitary autonomous thyroid nodules: effect on thyroid size and early hypothyroidism

1986 ◽  
Vol 113 (2) ◽  
pp. 226-232 ◽  
Author(s):  
Laszlo Hegedüs ◽  
Dagmar Veiergang ◽  
Steen Karstrup ◽  
Jens Mølholm Hansen
Keyword(s):  
Thyroid Gland ◽  
Thyroid Function ◽  
Thyroid Nodules ◽  
Thyroid Volume ◽  
131I Therapy ◽  
Important Place ◽  
Gland Volume ◽  
Thyroid Gland Volume ◽  
One Year ◽  
Hyperthyroid Patients

Abstract. Thyroid function and thyroid gland volume, ultrasonically determined, were investigated in 27 hyperthyroid patients with solitary autonomous thyroid nodules before and during one year after 131I-treatment. Total thyroid volume decreased gradually from 40.9 ± 3.5 ml (mean ± sem) before treatment to 23.9 ± 1.8 ml (P < 0.001) at 3 months after 131I-treatment. No further change was observed. All but two patients received only one dose of 131I, and in spite of a significant decrease also of the non-adenoma side of the gland, none became hypothyroid. We conclude that 131I-therapy has an important place in the treatment of solitary autonomous thyroid nodules since all our patients became euthyroid within 3 months, only 2 of 27 patients needed more than one dose of 131I, no cases of hypothyroidism occurred, and thyroid volume was substantially decreased.

ULTRASONOGRAPHIC MEASUREMENT OF THYROID GLAND VOLUME IN TURKISH NEONATES AND ASSESSMENT OF REGIONAL DIFFERENCES

2014 ◽  
Author(s):  
Sibel Bayramoglu ◽  
Sema Aksoy ◽  
Akgun Unat ◽  
Fatma Beyazal Celiker ◽  
Seyma Yıldız ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Regional Differences ◽  
Gland Volume ◽  
Thyroid Gland Volume

Can Thyroid Ultrasonography Predict Substernal Extension or Tracheal Compression in Goiters?

2018 ◽  
Vol 69 (4) ◽  
pp. 422-429
Author(s):  
Hedyeh Ziai ◽  
Nicole L. Lebo ◽  
Ania Z. Kielar ◽  
Michael J. Odell
Keyword(s):  
Thyroid Gland ◽  
Characteristic Curve ◽  
Area Under The Curve ◽  
Thyroid Volume ◽  
Classification Systems ◽  
Tracheal Compression ◽  
Gland Volume ◽  
The Us ◽  
Thyroid Gland Volume ◽  
Preoperative Ct

Purpose To determine whether an ultrasonography (US)-defined thyroid volume can accurately predict substernal extension or tracheal narrowing. Methods After research ethics approval, we identified patients with thyroid nodules investigated with both US and computed tomography (CT). Reviewers assigned scores for both substernal extension and tracheal compression on CT using pre-established classification systems. Statistical analysis with receiver operating characteristic curve analysis was performed to find the US-determined thyroid volume thresholds that correlated with each substernal extension and tracheal compression. Results This study included 120 patients (mean age 63.4 years; SD ± 15.9; 67% female). Thirty-five patients (29%) had substernal extension. The mean US total thyroid gland volume in patients with and without substernal extension were 92.4 and 37.6 cm3, respectively ( P < .001). 86% of patients with substernal extension had tracheal narrowing vs. 27% of patients without substernal extension ( P < .0001). A cutoff dominant gland volume of ≥37.5 cm3 showed 83% sensitivity and 79% specificity for substernal extension (area under the curve [AUC] = 0.84). A total thyroid gland volume threshold of ≥37.8 cm3 showed 89% sensitivity and 87% specificity for any degree of tracheal narrowing (AUC = 0.90). Conclusions This study suggests that US volumes may be used as a predictor to identify those patients with thyroid enlargement who are most at risk of substernal extension and tracheal compression and who may benefit from preoperative CT imaging for optimal surgical and anesthetic planning.

Normative Data of Thyroid Gland Volume in South Indian Neonates and Infants

2018 ◽  
Vol 85 (12) ◽  
pp. 1045-1049
Author(s):  
Sudha Rathna Prabhu ◽  
Shriraam Mahadevan ◽  
Sujatha Jagadeesh ◽  
Dharani Dharan ◽  
Chandra Ganesh ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Normative Data ◽  
Gland Volume ◽  
South Indian ◽  
Thyroid Gland Volume ◽  
Neonates And Infants

Measuring Thyroid Gland Volume: Should We Change the Correction Factor?

2006 ◽  
Vol 186 (1) ◽  
pp. 234-236 ◽  
Author(s):  
Wael Shabana ◽  
Els Peeters ◽  
Michel De Maeseneer
Keyword(s):  
Thyroid Gland ◽  
Correction Factor ◽  
Gland Volume ◽  
Thyroid Gland Volume

Morphological characteristic and assessment of changesin the main structural components of the histohematological barrier of the thyroid tissue in cases of the sudden cardiac death from alcoholic cardiomyopathy

2017 ◽  
Vol 8 (5) ◽  
pp. 30-34
Author(s):  
Olga V. Sokolova ◽  
Orazmurad D. Yagmurov ◽  
Ruslan A. Nasyrov
Keyword(s):  
Sudden Cardiac Death ◽  
Thyroid Gland ◽  
Cardiac Death ◽  
Morphological Changes ◽  
Cytotoxic Action ◽  
Structural Components ◽  
Alcoholic Cardiomyopathy ◽  
Endothelial Lining ◽  
Gland Tissue ◽  
Thyroid Gland Tissue

A retrospective analysis of acts of forensic medical autopsies from the archive of St. Petersburg GBUS BSME and a histological study of thyroid gland tissue in 188 cases (95 women and 93 men) were carried out with statistical processing of the obtained results for the purpose of studying and assessing the morphological changes in the main components of the histohematological barrier of thyroid gland tissue in cases of the sudden cardiac death from alcoholic cardiomyopathy. The decrease in the weight of the thyroid gland in the investigated cases and the revealed morphological signs, indicative of a decrease in the memory function of the thyroid gland were found and can be caused by the prolonged toxic effect of ethanol and its metabolites. Morphological changes in the endothelial lining of the vessels of the microcirculatory bed are caused both by the direct cytotoxic action of ethanol and its metabolites and by the action of mediators, the release of which occurs as a result of stimulation of the reactive cells, which leads to swelling, deformation and increased activity of endothelial cell membranes with the expansion of intercellular spaces and the development of increased permeability of the endothelial lining, which, in its turn, contributes to disruption of electrolyte transport and nutrients transport with changes trophism thyroid gland tissue, which is a substrate for the appearance of dystrophic and necrobiotic processes in main structural components of the histogematogenous barrier of the thyroid gland. The revealed morphological changes in thyroid gland tissue in cases of death from alcoholic cardiomyopathy have a non-specific nature and should be considered in conjunction with other visceral manifestations that are a reflection of alcohol intoxication during the chronic alcoholism.

scholarly journals Thyrocytes as the Target Cells for Hhv-6 Infection in Patients with Autoimmune Thyroiditis / Tireocīti Kā Cilvēka Herpesvīrusa-6 Infekcijas Mēríšūnas Pacientiem Ar Autoimūno Tireoidītu

2016 ◽  
Vol 70 (4) ◽  
pp. 160-164
Author(s):  
Alina Sultanova ◽  
Maksims Èistjakovs ◽  
Egils Cunskis ◽  
Katerina Todorova ◽  
Russy Russev ◽  
...  
Keyword(s):  
Viral Load ◽  
Thyroid Gland ◽  
Autoimmune Thyroiditis ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Human Herpesvirus ◽  
Target Cells ◽  
Tissue Samples ◽  
Gland Tissue ◽  
Thyroid Gland Tissue

Abstract Human herpesvirus-6 (HHV-6) is a ubiquitous betaherpesvirus with immunomodulating properties that have been suggested to play an important role in the development of several autoimmune disorders. Although the primary targets for HHV-6 replication, both in vitro and in vivo, are CD4+ and CD8+ T lymphocytes, some studies have reported the presence of HHV-6 sequences in different solid organs, including in the thyroid gland, showing possible involvement of this herpesvirus in development of autoimmune thyroid disease. The aim of this study was to determine loads of HHV-6 in thyroid gland tissue in comparison to those in peripheral blood of patients with autoimmune thyroiditis. Seven patients [women mean age 45 (28-65)] with histologically confirmed autoimmune thyroiditis were enrolled in this study. Fluorescence-activated cell sorting was used to distinguish and sort lymphocyte populations from peripheral blood mononuclear cells of patients. HHV-6 load was determined by real-time PCR for peripheral blood and thyroid gland tissue samples. Additionally, all results from molecular analyses were compared with histological results obtained by light microscopy. Viral load was detected only in one (46 viral copies/ 1×106cells) blood sample; others were under the detection limit of the used kit. However, in all HHV-6 positive tissue samples viral load was detected in the range of 132-1620 viral copies/106 cells. Substantial HHV-6 load in lymphocyte subpopulations was detected in two of seven patients. HHV-6 load was detected in NK and CD95+ cells of two patients. The obtained results show that thyroid gland cells (tyrocytes) act as target cells for HHV-6.

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