scholarly journals Impact of hysterectomy on uterine cancer incidence rates in Egypt

Author(s):  
Amr S Soliman ◽  
Saad Alshahrani MD PhD ◽  
Robert M Chamberlain PhD ◽  
Ahmed Hablas MD ◽  
Steven Remmenga MD ◽  
...  

Background: Uterine cancer is one of the common women’s cancers worldwide. There are significant variations in uterine cancer incidence rates globally and the incidence in Egypt is one of the lowest. Several studies have shown that hysterectomy might be a factor in underestimating the observed incidence of uterine cancer. However, no studies have been conducted in Egypt to examine this observation. Methods: Pathologic reports of all 1040 hysterectomy specimens examined in 2013 and 2014 in the Gharbiah province, Egypt were abstracted. Prevalence of hysterectomy was estimated and used for adjusting the incidence rate of uterine cancer in the Gharbiah population-based registry by excluding the hysterectomized women from the population at risk. Pre- and post- adjustment rates were compared and 95% confidence intervals (CIs) were calculated. Results: The prevalence of hysterectomy was estimated as 13.1 per 10,000 women, 95% CI (12.65-13.66). The prevalence of hysterectomy did not have a significant impact on uterine cancer incidence [pre-adjustment (2.78, 95% CI 2.58-3.00) and post-adjustment (2.79, 95% CI 2.58-3.00)]. Observing a significant effect of hysterectomy on underestimating the incidence of uterine cancer in this population required multiplying the observed prevalence by at least 110 times. Discussion: This study confirmed the previously documented low incidence of uterine cancer in this population of Egypt. The lack of evidence about the possible role of hysterectomy in lowering uterine cancer incidence justifies the need for additional research to identify the protective factors for uterine cancer in this population.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 4538-4538
Author(s):  
Tamer Dafashy ◽  
Daniel Phillips ◽  
Mohamed Danny Ray-Zack ◽  
Preston Kerr ◽  
Yong Shan ◽  
...  

4538 Background: Exposure to aromatic amines is a risk factor for bladder cancer. Incidence rates according to proximity to oil refineries are largely unknown. We sought to determine proximity of oil refineries and bladder cancer incidence in the State of Texas which is home to the largest number of oil refineries in the United States. Methods: We used the Texas Cancer Registry database to identify patients diagnosed with bladder cancer from January 1, 2001 to December 31, 2014. The U.S. census data from 2010 was used to ascertain overall population size, age and sex distributions. Heat maps of the 28 active oil refineries in Texas were developed. Incidence of bladder cancer were compared according to proximity ( < 10 vs. ≥ 10 miles) to an oil refinery. Risk ratios were adjusted using a Poisson regression model. Results: A total of 45,517 incident bladder cancer cases were identified of which 5,501 cases were within 10 miles of an oil refinery. In adjusted analyses, bladder cancer risk was significantly greater among males vs. females (Relative Risk (RR) 3.41, 95% Confidence Interval (CI), 3.33-3.50), and greater among people living within 10 miles from an oil refinery than those living outside a 10-mile radius from an oil refinery (RR 1.19, 95% CI, 1.08-1.31). Conclusions: People living within 10 miles from oil refineries were at greater risk for bladder cancer. Further research into exposure to oil refineries and bladder cancer incidence is warranted.


2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Lisa W. Chu ◽  
Jamie Ritchey ◽  
Susan S. Devesa ◽  
Sabah M. Quraishi ◽  
Hongmei Zhang ◽  
...  

African American men have among the highest prostate cancer incidence rates in the world yet rates among their African counterparts are unclear. In this paper, we compared reported rates among black men of Sub-Saharan African descent using data from the International Agency for Research on Cancer (IARC) and the National Cancer Institute Surveillance, Epidemiology, and End Results Program for 1973–2007. Although population-based data in Africa are quite limited, the available data from IARC showed that rates among blacks were highest in the East (10.7–38.1 per 100,000 man-years, age-adjusted world standard) and lowest in the West (4.7–19.8). These rates were considerably lower than those of 80.0–195.3 observed among African Americans. Rates in Africa increased over time (1987–2002) and have been comparable to those for distant stage in African Americans. These patterns are likely due to differences between African and African American men in medical care access, screening, registry quality, genetic diversity, and Westernization. Incidence rates in Africa will likely continue to rise with improving economies and increasing Westernization, warranting the need for more high-quality population-based registration to monitor cancer incidence in Africa.


2003 ◽  
Vol 12 (5) ◽  
pp. 359-365 ◽  
Author(s):  
L.S. Freedman ◽  
M. Barchana ◽  
S. Al-Kayed ◽  
M.B. Qasem ◽  
J.L. Young ◽  
...  

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