scholarly journals Comparison of the efficacy of two types of hemodialysis catheters: the VectorFlow vs. Palindrome catheters

2019 ◽  
Vol 6 (6) ◽  
pp. 3244-3247
Author(s):  
Veisi Ali ◽  
Sobhiyeh MohammadReza

Introduction: Permanent vascular access via catheters is a critical factor for patients who need long-term hemodialysis. Differences in the design and mechanical factors can affect efficacy and survival of the permanent catheters. Modifications in the designs of the catheters can decrease the likelihood of damaging blood vessels as well as thrombosis formation and malfunction of the catheters. Objective: To compare survival of VectorFlow, complete symmetry of distal tip and offsetting of its side holes, with those of Palindrome, a complete symmetrical catheter. Methods: In this study, 146 CKD (chronic kidney disease) patients who required chronic hemodialysis were divided into VectrFlow (76 subjects) and Palindrome (70 subjects) catheter groups. The patients were followed for six months and the survival rate in each group was determined. Results: Mean (+/-SD) survival time in the VectorFlow catheter group (6.55+/-3.88 months, 2 to 24 months) was longer than in the Palindrome catheter group (5.22+/-2.88 months, one to 13 months). After six months, the VectorFlow catheter group (40 cases, 54.8%) had a higher number of patients, having a functioning catheter in place than the Palindrome group (26 cases, 382%); P= 0.04. Conclusion: The VectorFlow hemodialysis catheter had a better survival rate after 6 months when compared to the Palindrome catheter. We recommend using this catheter in CKD patients, who require a long-term permanent catheter.  

2019 ◽  
Vol 4 (1) ◽  

Indwelling venous catheters provide essential functional vascular access for patients requiring emergent or urgent hemodialysis, though their long-term use is practically limited by known complications including increased rates of infection as compared with surgically created arteriovenous (AV) fistulas. Converging lines of evidence also support that chronic kidney disease (CKD) represents a pro-inflammatory state, an environment with active cellular and inflammatory pathobiology. Accordingly, implantation of catheters for even short-term use is associated with a fibrinthrombin-cellular matrix often forming around the catheter. This “biomass” long considered innocuous, can cause occlusion of the catheter, contributing to reduced flow rates during dialysis. It may also result in embolic injury of downstream structures. This case report identifies a complex catheter-related biomass remaining after removal of the hemodialysis catheter and focuses on two concerns. First, intravenous masses associated with the catheter, or remaining after removal may provoke embolic and direct hemodynamic-related injury. But perhaps less obvious is their potential linkage to vascular immunoreactivity found in CKD. This latter potential may need to be part of the larger discussion surrounding the outcomes of such pathologic immunoresponsiveness in CKD patients on hemodialysis.


2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Eduardo Bustos-Vazquez ◽  
Eduardo Padilla-González

Abstract Background The growing number of patients with complex clinical profiles has contributed to the increasingly deaths. The aim is to estimate survival and risk factors associated with hospitalized COVID-19 patients with multimorbidity in the state of Hidalgo, Mexico during 2020 to April 2021. Material and Methods An observational, longitudinal, prospective and analytical study was carried out in 11,955 hospitalized COVID-19 patients with multimorbidity from the Epidemiological Surveillance System for Respiratory Disease of Hidalgo. The variables of interest were survival of hospital stay per day and multimorbidity adjusted for age, sex, occupation, days of demand for care, and days of mechanical ventilation use. Kapplan-Meiner estimators, Log-Rank tests and Cox proportional hazard method were using. Results Hospitalized COVID-19 patients with multimorbidity survival was 53.5%. The probability of survival is reduced to 50% from day 17 of hospital stay. The shortest survival rate corresponds to cases with Hypertension + Chronic Kidney Disease (RR: 9.46, 95% CI 2.63-37.92), Diabetes + Hypertension + Chronic Kidney Disease (RR: 1.83, 95% CI 1.52-2.20), Diabetes + Hypertension + Obesity (RR: 1.35, 95% CI 1.16-1.57) and Diabetes + Hypertension (RR: 1.31, 95% CI 1.19-1.45). The use of mechanical ventilation for more than 14 days increases the survival rate (RR: 0.53, 95% CI 0.49-0.57). The survival rate from occupation increase in employees, students and health workers compared to the unemployed. Conclusions Multimorbidity increases the effect of the clinical and epidemiological interrelationships of the coexistence of multiple diseases in the same individual and reduces the survival of COVID-19 in hospitalized patients.


Author(s):  
Saurabh Singhal

Background: In people with chronic kidney disease (CKD), cognitive decline is one of the major causes for poor outcome in terms of quality of life and survival rate. Previous studies have found an association between cardiovascular disease and psychiatric disorders in people with CKD. Physicians should keep in mind that the psychiatric changes and cognitive decline seen in all stages of CKD is to be detected early in the course of the disease, for timely management of it and for better outcome in terms of survival rate. Aim: The goal of this study is to evaluate cognitive performance in patients with chronic renal disease Material and Method: The study was conducted from March 2019 to april 2021 in department of general medicine and nephrology clinic at KDMCH, Mathura. Between March 2019 to april 2021, baseline data were obtained. The study included 108 participants (58 with CKD and 50 with ESKD). ESKD patients were ‘CKD patients with dialysis’. Various tests were used to assess brain function. Results: ESKD patients had significantly lower scores on the 3MS, TMT-A and TMT-B trials, with a difference between TMT-A and B than CKD patients. In ESKD patients, the numbers less than 3MS of speech and fluency memory, as well as visuo-position and structure, were significantly lower. ESKD patients had the highest number of patients with psychiatric disorders, as measured by the outpatient testing scores listed above 3MS, TMT-A, and TMT-B. ESKD patients had significantly higher levels of depression than CKD patients. Conclusion: Higher cognitive decline was found in the ESKD group in comparision to non-dialysis CKD group. Also ESKD was associated with higher rates of cerebro-vascular disease, cardio-vascular disease and peripheral artery disease. Keywords: Chronic Kidney Disease, ESKD, eGFR and cognitive impairment


Author(s):  
Tamami Nakamura ◽  
Akihito Mikamo ◽  
Yutaro Matsuno ◽  
Akira Fujita ◽  
Hiroshi Kurazumi ◽  
...  

Abstract OBJECTIVES Postoperative acute kidney injury (AKI) is a common complication associated with increased long-term mortality after cardiothoracic surgery. However, AKI after total aortic arch replacement (TAR) is not well studied. This study aimed to investigate the prognosis and impact of AKI on the long-term outcomes of chronic kidney disease (CKD) patients undergoing TAR. METHODS We included 208 patients who underwent TAR between September 2003 and December 2014. Patients were divided into a CKD (n = 83, 40%) and non-CKD (n = 125, 60%) group. The definition of AKI followed the Risk, Injury, Failure, Loss of kidney function and End-stage kidney disease (RIFLE) criteria. Independent risk factors for all-cause death and AKI were identified with multivariable analysis. RESULTS Postoperative AKI was observed in 24 patients (29%) and 39 patients (31%) of CKD and non-CKD groups, respectively. The survival rate of CKD patients was significantly lower than that of non-CKD patients (P = 0.02). Among CKD patients, the 5-year survival rate was 57% in those with AKI group and 92% in those without AKI; prognosis was significantly poorer in patients with AKI (P = 0.001). In the non-CKD group, there was no difference in prognosis between patients with or without AKI (P = 0.77). Multivariable logistic regression analysis revealed that intraoperative blood loss of ≥600 ml was the only predictor of AKI in the CKD group (odds ratio 4.32, P = 0.04). CONCLUSIONS CKD is associated with reduced long-term survival after TAR. Postoperative AKI strongly influences long-term survival in CKD patients only.


2020 ◽  
Vol 6 (1) ◽  
pp. 55-60
Author(s):  
Khabib Barnoev ◽  
◽  
Sherali Toshpulatov ◽  
Nozima Babajanova ◽  

The article presents the results of a study to evaluate the effectiveness of antiaggregant therapy on the functional status of the kidneys in 115 patients with stage II and III chronic kidney disease on the basis of a comparative study of dipyridamole and allthrombosepin. Studies have shown that long-term administration of allthrombosepin to patients has led to improved renal function.


2020 ◽  
Vol 6 (1) ◽  
pp. 49-54
Author(s):  
Khabib Barnoev ◽  

The article presents the results of a study to assess the functional reserve of the kidneys against the background of a comparative study of antiaggregant therapy dipyridamole and allthrombosepin in 50 patients with a relatively early stage of chronic kidney disease. Studies have shown that long-term administration of allthrombosepin to patients has resulted in better maintenance of kidney functional reserves. Therefore, our research has once again confirmed that diphtheridamol, which is widely used as an antiaggregant drug in chronic kidney disease, does not lag behind the domestic raw material allthrombosepin


2018 ◽  
Vol 21 (6) ◽  
pp. 1142-1149 ◽  
Author(s):  
Meghan J. Elliott ◽  
Joanna E. M. Sale ◽  
Zahra Goodarzi ◽  
Linda Wilhelm ◽  
Andreas Laupacis ◽  
...  

2021 ◽  
Vol 96 (1) ◽  
pp. 40-51 ◽  
Author(s):  
Massini A. Merzkani ◽  
Aleksandar Denic ◽  
Ramya Narasimhan ◽  
Camden L. Lopez ◽  
Joseph J. Larson ◽  
...  

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