Hazards of Edathamil (EDTA) Therapy in Lead Intoxication

PEDIATRICS ◽  
1961 ◽  
Vol 28 (1) ◽  
pp. 161-162
Author(s):  
B. F. ANDREWS

It occurred to me when reading the Report of the Subcommittee on Accidental Poisoning, "Statement on Diagnosis and Treatment of Lead Poisoning in Childhood" (Pediatrics, 27:676, 1961), that mention of the potentially severe toxic effects of intravenously given CaEDTA should have been made. Five fatalities ascribed to CaEDTA have been reported from Germany and one from the United States in recent years. Also, fatalities have been associated with NaEDTA in the treatment of hypercalcemia. Pathologic examination of renal tissue from these patients revealed lesions of the proximal tubules.

2020 ◽  
Vol 09 ◽  
Author(s):  
Nataly S. Beck ◽  
Melanie L. Lean ◽  
Kate V. Hardy ◽  
Jacob S. Ballon

Background: The typical age of onset for psychotic disorders is concurrent with the typical age of enrollment in higher education. College and graduate students often experience new academic and social demands that may leave them vulnerable to substance use and mental health problems, including the initial onset of a psychotic episode. Objective: To provide a current overview of the guidelines and literature for the diagnosis and treatment of first-onset psychosis with special consideration for the college and graduate student population in the United States. To highlight areas of need and provide recommendations for clinicians who work at educational institutions and their health services, along with general psychiatrists and psychologists who work with post-secondary education populations, to help close the treatment gap. Method: A review of interventions and best practice for the treatment of early psychosis in college students was conducted, informed by the authors’ current experience as clinicians with this population at a United States university. Results: Thorough psychiatric interviews and screening tools can help in the early identification of individuals at clinical high risk for and at first onset of psychosis. Coordinated specialty care services are the gold standard for early psychosis services, including psychotherapy (such as cognitive behavioral therapy and individual resiliency training), as well as support for a student to return to school or work. Individuals experiencing a first episode of psychosis in general respond better to lower doses of antipsychotics and may also experience more adverse effects. Conclusion: Return to a high level of functioning is possible in many cases of first onset of psychosis, and early identification and treatment is essential.


2018 ◽  
Vol 13 (7) ◽  
pp. 332-336
Author(s):  
Tracy Perron ◽  
Kelly Hartt ◽  
Danielle McCann ◽  
Rachel McGowan ◽  
Natalie Segers

Author(s):  
Michael Root

Racial categories are used in the biomedical sciences both at the population and individual level. At the population level, race is used in fields like epidemiology, to describe and explain variations in the rate or risk of morbidity and mortality within the United States, and at the individual level, race is used in the hospital and clinic, in the diagnosis and treatment of disease. Both uses are controversial and raise questions about the nature and importance of racial categories, such as which uses benefit individuals and which benefit groups.


2018 ◽  
Vol 36 (5) ◽  
pp. 483-491 ◽  
Author(s):  
Paul D. Brown ◽  
Manmeet S. Ahluwalia ◽  
Osaama H. Khan ◽  
Anthony L. Asher ◽  
Jeffrey S. Wefel ◽  
...  

An estimated 20% of patients with cancer will develop brain metastases. Approximately 200,000 individuals in the United States alone receive whole-brain radiotherapy (WBRT) each year to treat brain metastases. Historically, the prognosis of patients with brain metastases has been poor; however, with new therapies, this is changing. Because patients are living longer following the diagnosis and treatment of brain metastases, there has been rising concern about treatment-related toxicities associated with WBRT, including neurocognitive toxicity. In addition, recent clinical trials have raised questions about the use of WBRT. To better understand this rapidly changing landscape, this review outlines the treatment roles and toxicities of WBRT and alternative therapies for the management of brain metastases.


2017 ◽  
Vol 64 (9) ◽  
pp. 1244-1250 ◽  
Author(s):  
Karlyn D. Beer ◽  
Sarah A. Collier ◽  
Fan Du ◽  
Julia W. Gargano

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Muhammed Atere ◽  
Lloyd Muzangwa ◽  
Foma Munoh Kenne ◽  
Cherry Hanna ◽  
Jessie Saverimuttu ◽  
...  

Malaria is transmitted by the Plasmodium parasite, and most of the cases reported in the United States are often as a result of patients with recent return from endemic areas. Prompt diagnosis and treatment, particularly if there is severe parasitemia and drug failure, is essential in preventing mortality. Our patient had an unusual rapid rise in parasite but susceptible to intravenous artesunate.


2013 ◽  
Vol 16 (3) ◽  
pp. A127
Author(s):  
M. Daubresse ◽  
H.Y. Chang ◽  
S. Viswanathan ◽  
Y. Yu ◽  
N. Shah ◽  
...  

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