Needles for Percutaneous Renal Biopsy in Infants and Children

PEDIATRICS ◽  
1970 ◽  
Vol 46 (5) ◽  
pp. 788-789
Author(s):  
Jack Metcoff
Keyword(s):  
Young Children ◽  
Renal Biopsy ◽  
Infants And Children ◽  
Adult Type ◽  
Biopsy Needle ◽  
Percutaneous Renal Biopsy ◽  
Relative Safety ◽  
In Infants And Children ◽  
Infants And Young Children

The thin musculature and relatively small kidneys of infants and young children do not readily accommodate the rather heavy percutaneous renal biopsy needle with its large, projecting, cutting blades, which has been used with relative safety and success in adults. For use in children, the reduction in length of the adult-type needle usually is accomplished by shortening the length of the shaft. This is done by removing a segment at the end opposite to the cutting blades, without diminishing the projection of these blades. The weight of the Franklin-Silverman small version, commercially available, is about 17 gm. The cutting blades project about 22 mm.

Assessment of Clinicopathological Features in Infants and Children with Cow�s Milk Protein Allergy

2019 ◽  
Vol 69 (12) ◽  
pp. 3573-3576
Author(s):  
Ileana Puiu ◽  
Elena Catalina Bica ◽  
Venera Cristina Dinescu ◽  
Otilia Constantina Rogoveanu ◽  
Alexandra Oltea Dan ◽  
...  
Keyword(s):  
Young Children ◽  
Milk Protein ◽  
Milk Proteins ◽  
Clinicopathological Features ◽  
Infants And Children ◽  
Pediatric Clinic ◽  
Number Of Patients ◽  
The Status ◽  
In Infants And Children ◽  
Infants And Young Children

The aim of our study was to evaluate the clinicopathological features in infants and young children with cow�s milk protein allergy. Cow�s milk protein allergy (CMPA) is one of the most common food allergy in children. Thus, we conducted a descriptive observational study, which was carried out in the First Pediatric Clinic of the Craiova County Emergency Clinical Hospital, in the period 2015-2017, which included 138 infants and young children diagnosed with cow�s milk protein allergy. An improvement in digestive symptomatology during the status period of the disease was observed, especially in what diarrheal stools are concerned as their incidence has decreased. In fact, gastroesophageal reflux is the most common manifestation in infants and children with CMPA, while mean acute otitis is present only in a small number of patients. In conclusion we can say that a good knowledge of the clinicopathological features in children with allergy to cow�s milk proteins allows a superior therapeutic attitude and ensures a normal life for children and infants suffering from this type of allergy.

STUDIES ON OESTROGEN METABOLISM IN INFANTS AND CHILDREN

1961 ◽  
Vol 37 (2) ◽  
pp. 241-252 ◽  
Author(s):  
M. Barr ◽  
E. Diczfalusy ◽  
K. G. Tillinger
Keyword(s):  
Urinary Excretion ◽  
Intramuscular Injection ◽  
Infants And Children ◽  
Adult Type ◽  
Before And After ◽  
Second Year ◽  
Pre Treatment ◽  
Urine Specimens ◽  
In Infants And Children ◽  
Infants And Young Children

ABSTRACT The urinary excretion of oestrone (3-hydroxy-oestra-1,3,5(10)-triene-17-one), 17β-oestradiol (oestra-1,3,5(10)-triene-3,17β-diol) and oestriol (oestra-1,3,5(10)-triene-3,16α,17β-triol) was studied in infants and children before and after the intramuscular injection of 17β-oestradiol and oestriol, respectively. No measurable amounts of these oestrogens could be detected in the urine specimens collected during the pre-treatment period. Administration of 500 μg of 17β-oestradiol in oil to infants of 2 to 10 months of age did not give rise to measurable amounts of urinary oestrone or oestradiol; there was, however, a limited increase in oestriol excretion, corresponding to approximately 2 per cent of the administered dose. When the same amount of 17β-oestradiol was administered to children aged 2.5 to 9 years, significant amounts of oestrone + oestradiol (corresponding to 3.5 % of the administered dose) were excreted in the urine in addition to considerable amounts of oestriol (approximately 6 % of the administered dose). Following the administration of 500 μg of oestriol in oil to infants and children (2 to 36 months of age) only some 14 % of the administered oestriol could be recovered from the urine and only 2 % from the faeces. It is concluded that the intermediary metabolism of 17β-oestradiol in infants is significantly different from that of adults. It is suggested that some time during the second year of life the oestradiol metabolism assumes the adult type. It is also suggested that – in contradistinction to the situation in the adult – in infants and young children oestriol does not represent a final stage in oestrogen metabolism, but rather an intermediate one, and that certain aspects of the oestrogen metabolism do not assume the adult type before the fourth year of life, or perhaps later.

Percutaneous Renal Biopsy in Infants and Young Children

1987 ◽  
Vol 137 (6) ◽  
pp. 1325-1325
Author(s):  
M. Sweet ◽  
B.H. Brouhard ◽  
F. Ramirez-Seijas ◽  
A. Kalia ◽  
L.B. Travis
Keyword(s):  
Young Children ◽  
Renal Biopsy ◽  
Percutaneous Renal Biopsy ◽  
Infants And Young Children

Real-Ear-to-Coupler Difference Predictions as a Function of Age for Two Coupling Procedures

2002 ◽  
Vol 13 (08) ◽  
pp. 407-415 ◽  
Author(s):  
Marlene P. Bagatto ◽  
Susan D. Scollie ◽  
Richard C. Seewald ◽  
K. Shane Moodie ◽  
Brenda M. Hoover
Keyword(s):  
Young Children ◽  
Infants And Children ◽  
Regression Equations ◽  
Predictive Equations ◽  
Subject Variability ◽  
Predicted Values ◽  
Age Range ◽  
Infants And Young Children

The predicted real-ear-to-coupler difference (RECD) values currently used in pediatric hearing instrument prescription methods are based on 12-month age range categories and were derived from measures using standard acoustic immittance probe tips. Consequently, the purpose of this study was to develop normative RECD predicted values for foam/acoustic immittance tips and custom earmolds across the age continuum. To this end, RECD data were collected on 392 infants and children (141 with acoustic immittance tips, 251 with earmolds) to develop normative regression equations for use in deriving continuous age predictions of RECDs for foam/acoustic immittance tips and earmolds. Owing to the substantial between-subject variability observed in the data, the predictive equations of RECDs by age (in months) resulted in only gross estimates of RECD values (i.e., within ± 4.4 dB for 95% of acoustic immittance tip measures; within ± 5.4 dB in 95% of measures with custom ear molds) across frequency. Thus, it is concluded that the estimates derived from this study should not be used to replace the more precise individual RECD measurements. Relative to previously available normative RECD values for infants and young children, however, the estimates derived through this study provide somewhat more accurate predicted values for use under those circumstances for which individual RECD measurements cannot be made.

Vitamin Intake of 3- to 36-Month-Old German Infants and Children – Results of the DONALD-Study

1999 ◽  
Vol 69 (4) ◽  
pp. 285-291 ◽  
Author(s):  
Alexy ◽  
Kersting ◽  
Sichert-Hellert ◽  
Manz ◽  
Schöch
Keyword(s):  
Young Children ◽  
Reference Values ◽  
Age Groups ◽  
Infants And Children ◽  
Infant Food ◽  
Diet Records ◽  
Lack Of Information ◽  
Vitamin Intake ◽  
First Year Of Life ◽  
Infants And Young Children

Infants and young children are a vulnerable group with regard to nutrition. However, there is a lack of information about the dietary composition of healthy German infants and children. Therefore, the intake of vitamins (A, C, E, B1, B2, B6, folate, niacin) was assessed in 354 healthy German infants and children aged 3 to 36 months from 3-day-weighed diet records and compared with German, European and US reference values. Intake of all B-vitamins (B1, B2, B6, folate, niacin) increased during the first 3 years of life, whereas intake of vitamin E decreased. Intake of vitamin A and C varied between age groups. The highest levels of the nutrient densities of most vitamins were found at the end of the first year of life. Depending on the reference values chosen, the vitamin supply of the study population ranged between sufficient and very good. The reported satisfactory intake of vitamins in infants and young children in this study gives rise to the question of whether the current extent of fortification of commercial infant food in Germany is necessary.

scholarly journals Fecal S100A12 in Healthy Infants and Children

2013 ◽  
Vol 35 ◽  
pp. 295-299 ◽  
Author(s):  
A. S. Day ◽  
M. Ehn ◽  
R. B. Gearry ◽  
D. A. Lemberg ◽  
S. T. Leach
Keyword(s):  
Young Children ◽  
Elevated Level ◽  
Gastrointestinal Symptoms ◽  
Infants And Children ◽  
Healthy Children ◽  
Term Infants ◽  
Healthy Infants ◽  
Stool Samples ◽  
Serial Samples ◽  
In Infants And Children

Background and Aims. Fecal S100A12 is shown to be a useful noninvasive marker of gut inflammation. However, the studies to date have not characterised the patterns of expression in healthy young children. This study aimed to determine S100A12 levels in infants and children without symptoms of underlying gut disease.Methods. Stool samples were collected from healthy infants (<12 months) and children without gastrointestinal symptoms. Faecal S100A12 was measured by immunoassay.Results. Fifty-six children were recruited. Serial samples were obtained from seven term infants over the first 6 months of life. Single samples were obtained from 49 healthy children ranging from 0.16 to 13.8 years of age. Median S100A12 levels were 0.5 mg/kg (ranging from 0.39 to 25) in the healthy children, with high values (>10 mg/kg) in five infants only. There was no variation between gender. Median S100A12 levels in healthy infants remained below the established normal cut-off from birth to six months of age.Conclusion. S100A12 levels in well infants and children are almost exclusively lower than the standard cut-off. Transiently higher levels may be seen in early infancy. An elevated level of S100A12 in children older than 12 months of age is likely to represent organic gut disease.

scholarly journals The efficacy of blind versus real-time ultrasound-guided percutaneous renal biopsy in developing country

2019 ◽  
Vol 7 ◽  
pp. 205031211984977 ◽  
Author(s):  
Wanjak Pongsittisak ◽  
Naphat Wutilertcharoenwong ◽  
Tanun Ngamvichchukorn ◽  
Sathit Kurathong ◽  
Chutima Chavanisakun ◽  
...  
Keyword(s):  
Renal Biopsy ◽  
Real Time ◽  
Resource Constraint ◽  
Bleeding Complications ◽  
Ultrasound Guided ◽  
Biopsy Needle ◽  
Percutaneous Renal Biopsy ◽  
Renal Biopsies ◽  
Lower Egfr ◽  
Adequate Tissue

Introduction: Renal biopsy is a useful diagnostic procedure. In developing countries, two techniques of renal biopsy, blind percutaneous renal biopsy and real-time ultrasound-guided percutaneous renal biopsy, have been performed. The majority of studies compared these using different types and sizes of biopsy needle. The aim of this study was to compare both techniques in resource constraint country. Method: We reviewed renal biopsy database, between 1 January 2014 to 30 June 2017. The primary outcome was the total number of glomeruli. The other outcomes were tissue adequacy and bleeding complications. We also analyzed multivariable logistic regression to find factors associated with tissue adequacy and bleeding complications. Result: Of the 204 renal biopsies, 100 were blind percutaneous renal biopsy and 104 real-time ultrasound-guided percutaneous renal biopsy. The number of native renal biopsies was 169 (82.8%). Baseline characteristics of two groups were comparable. The mean number of total glomeruli from real-time ultrasound-guided percutaneous renal biopsy was significantly more than blind percutaneous renal biopsy (20.8 ± 12.1 vs 16.0 ± 13.0, p = 0.001). The real-time ultrasound-guided percutaneous renal biopsy obtained more adequate tissues than blind percutaneous renal biopsy (45.2% vs 16%, p < 0.001) and was the only factor associated with adequate tissue. Moreover, 16 renal biopsies from blind percutaneous renal biopsy obtained inadequate tissue. The overall bleeding complications were not statistically different. We found being female, lower eGFR and lower hematocrit were associated with bleeding complications. Conclusion: In comparison with blind percutaneous renal biopsy, real-time ultrasound-guided percutaneous renal biopsy obtained more adequate tissue and number of glomeruli. While the complications of both were comparable. We encourage to practice and perform real-time ultrasound-guided percutaneous renal biopsy in resource constraint countries.

scholarly journals Interferon-Mediated Response to Human Metapneumovirus Infection

Viruses ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 505 ◽  
Author(s):  
Ifeanyi Uche ◽  
Antonieta Guerrero-Plata
Keyword(s):  
Young Children ◽  
Respiratory Diseases ◽  
Human Metapneumovirus ◽  
Infants And Children ◽  
Commercial Vaccine ◽  
Hmpv Infection ◽  
In Infants And Children

Human metapneumovirus (HMPV) is one of the leading causes of respiratory diseases in infants and children worldwide. Although this pathogen infects mainly young children, elderly and immunocompromised people can be also seriously affected. To date, there is no commercial vaccine available against it. Upon HMPV infection, the host innate arm of defense produces interferons (IFNs), which are critical for limiting HMPV replication. In this review, we offer an updated landscape of the HMPV mediated-IFN response in different models as well as some of the defense tactics employed by the virus to circumvent IFN response.

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