Corroborative Evidence for the Decreased Incidence of Urinary Tract Infections in Circumcised Male Infants

PEDIATRICS ◽  
1986 ◽  
Vol 78 (1) ◽  
pp. 96-99 ◽  
Author(s):  
Thomas E. Wiswell ◽  
John D. Roscelli
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
First Year ◽  
Us Army ◽  
Army Hospitals ◽  
Corroborative Evidence ◽  
Tract Infections ◽  
First Year Of Life

We report the results of a two-part study examining the incidence of urinary tract infection during the first year of life. In the first part of the investigation, we reviewed the occurrence of urinary tract infection in a cohort of 3,924 infants born at our institution during a 4-year period. Infection developed in 16 infants (0.41%). The incidence of urinary tract infection in noncircumcised males was greater than the incidence in both female (P < .004) and circumcised male (P < .001) infants. In the second part of the study, we explored the frequency of urinary tract infection in all infants born in US Army hospitals, worldwide, over a 10-year period. There were 422,328 infants born in army facilities during this time period. Subsequent hospitalization for urinary tract infection occurred for 1,825 (0.43%) infants during the first year of life. Overall, there was no male preponderance for infections in early infancy compared with females. After an equivalent incidence during the first month of life, female infants had significantly more infections than did male infants (P < .001). However, noncircumcised male infants had a higher incidence of urinary tract infection than female infants (P < .001). Additionally, noncircumcised male infants had a tenfold greater incidence of infection than circumcised male infants (P < .001). There was a significant decrease in the circumcision frequency rate during the 10-year study period (from 85.4% to 73.9%, P < .001). As the number of circumcisions decreased, there was a concomitant increase in the overall number of urinary tract infections in males (P <.02). A reduced incidence of infection may be at least one medical benefit of routine neonatal circumcision.

Larger Numbers Needed

PEDIATRICS ◽  
1987 ◽  
Vol 80 (5) ◽  
pp. 764-764
Author(s):  
THOMAS E. WISWELL
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
First Year ◽  
Infection Rates ◽  
Symptomatic Urinary Tract Infection ◽  
Tract Infections ◽  
First Year Of Life

In Reply.— Dr Altschul presents data on urinary tract infections during infancy and reports infection rates substantially lower than those we have previously reported.1,2 He then makes several conclusions based on these differences. His data indicate that the maximum infection rates would be 0.11% among girls and 0.02% and 0.12% among circumcised and uncircumcised boys, respectively. In contrast, from a population of 422,328 infants, we found the overall incidence of symptomatic urinary tract infection during the first year of life to be 0.57% in girls, 0.11% in circumcised boys, and 1.12% in uncircumcised boys.

Decreased Incidence of Urinary Tract Infections in Circumcised Male Infants

PEDIATRICS ◽  
1985 ◽  
Vol 75 (5) ◽  
pp. 901-903 ◽  
Author(s):  
THOMAS E. WISWELL ◽  
FRANKLIN R. SMITH ◽  
JAMES W. BASS
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Male Infant ◽  
Large Cohort ◽  
First Year ◽  
Tract Infections ◽  
First Year Of Life ◽  
Increased Susceptibility

In a recent report of 100 infants less than 8 months of age with urinary tract infection, it was noted that 95% of the male infants were not circumcised.1 The authors speculated from this observation that the uncircumcised male infant may have an increased susceptibility to urinary tract infection, but commented that the incidence of urinary tract infection in uncircumcised compared with circumcised infants was unknown. We report the results of a study documenting the incidence of unnary tract infection during the first year of life in a large cohort of infants born at our institution over an 18-month period and we also document the incidence of urinary tract infection in circumcised compared with uncircumcised male infants.

Urinary Tract Infections and the Uncircumcised State: An Update

1993 ◽  
Vol 32 (3) ◽  
pp. 130-134 ◽  
Author(s):  
Thomas E. Wiswell ◽  
Wayne E. Hachey
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Meta Analysis ◽  
Fold Increase ◽  
First Year ◽  
Us Army ◽  
Increased Risk ◽  
Army Hospitals ◽  
Tract Infections ◽  
First Year Of Life

In a two-part study of the circumcision status of boys with urinary tract infections (UTIs), we reviewed the occurrence of UTIs in 209,399 infants born in US Army hospitals worldwide from 1985 to 1990. During the first year of life, 1,046 (0.5%: 550 girls and 496 boys) were hospitalized for UTIs. Noncircumcised male infants had a 10-fold greater incidence of infection than did circumcised male infants. The frequency rate of circumcision rose significantly, from 70.3% to 80.2%, during the study period. Among uncircumcised boys younger than 3 months with UTIs, 23% had concomitant bacteremia involving the same organism. The second part of the study consisted of a meta-analysis of all nine previous reports on the circumcision status of boys with UTIs. These studies revealed a fivefold to 89-fold increased risk of infection in uncircumcised boys; the combined data yielded a 12-fold increase in UTIs in this population. Parents should be told of the lower risk of UTIs for circumcised boys during informed-consent counseling.

Risks From Circumcision During the First Month of Life Compared With Those for Uncircumcised Boys

PEDIATRICS ◽  
1989 ◽  
Vol 83 (6) ◽  
pp. 1011-1015
Author(s):  
Thomas E. Wiswell ◽  
Dietrich W. Geschke
Keyword(s):  
Renal Failure ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Surgical Trauma ◽  
Us Army ◽  
Army Hospitals ◽  
Tract Infections

The records of 136,086 boys born in US Army hospitals from 1980 to 1985 were reviewed for indexed complications related to circumcision status during the first month of life. For 100,157 circumcised boys, there were 193 complications (0.19%). These included 62 local infections, eight cases of bacteremia, 83 incidences of hemorrhage (31 requiring ligature and three requiring transfusion), 25 instances of surgical trauma, and 20 urinary tract infections. There were no deaths or reported losses of the glans or entire penis. By contrast, the complications in the 35,929 uncircumcised infants were all related to urinary tract infections. Of the 88 boys with such infections (0.24%), 32 had concomitant bacteremia, three had meningitis, two had renal failure, and two died. The frequencies of urinary tract infection (P < .0001) and bacteremia (P < .0002) were significantly higher in the uncircumcised boys. Serious complications from routine prepuce removal are rare and relatively minor. Circumcision may be beneficial in reducing the occurrence of urinary tract infections and their associated sequelae.

Circumcision

PEDIATRICS ◽  
1987 ◽  
Vol 80 (2) ◽  
pp. 303-304
Author(s):  
ROBERT S. THOMPSON ◽  
DIANE C. THOMPSON
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Retrospective Cohort ◽  
Fold Increase ◽  
First Year ◽  
Discharge Data ◽  
Army Hospitals ◽  
Retrospective Cohort Studies ◽  
Tract Infections ◽  
First Year Of Life

To the Editor.— Wiswell et al,1 in 1985, and Wiswell and Roscelli,2 in 1986, report three retrospective cohort studies (Tripler, Brooke, and all Army hospitals) in which the association of circumcision status (circumcised v noncircumcised) and subsequent hospitalizations for urinary tract infection in the first year of life is evaluated. Cases appear to have been determined from examination of available hospital discharge data and the diagnosis confirmed by suprapubic bladder tap or catheterization. The authors report a ten- to 20-fold increase in hospitalized urinary tract infections among noncircumcised boys in the first year of life.

Detection of tox A gene in Pseudomonas aeruginosa that isolates from different clinical cases by using PCR.

2018 ◽  
pp. 26
Author(s):  
Rana M. Abdullah Al-Shwaikh ◽  
Abbas Falih Alornaaouti
Keyword(s):  
Molecular Weight ◽  
Pseudomonas Aeruginosa ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Otitis Media ◽  
Urinary Tract Infections ◽  
Gel Electrophoresis ◽  
Wound Infections ◽  
Tract Infections

       Current study obtained (75) isolate of Pseudomonas aeruginosa collected from different cases included : 28 isolates from otitis media, 23 isolates from burn infections, 10 isolates from wound infections, 8 isolates from urinary tract infections and 6 isolates from blood, during the period between 1/9/2014 to 1/11/2014        The result revealed that the tox A gene was present in 54 isolates (72%) of Pseudomonas aeruginosa. The gel electrophoresis showed that the molecular weight of tox A gene was 352 bp. The result shows 17 isolates (60.71%) from otitis media has tox A gene, 18 isolates (78.26%) from burn followed by 8 isolate (80%) from wound infection and 5 isolates (62.5%) from urinary tract infection , finally 6 isolates (100%) from blood have this gene.

URINARY INFECTION AT DEPARTMENT OF UROLOGY OF HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

2018 ◽  
pp. 100-108
Author(s):  
Dinh Khanh Le ◽  
Dinh Dam Le ◽  
Khoa Hung Nguyen ◽  
Xuan My Nguyen ◽  
Minh Nhat Vo ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Urine Culture ◽  
Clinical Manifestations ◽  
University Hospital ◽  
E Coli ◽  
Positive Urine ◽  
Tract Infections

Objectives: To investigate clinical characteristics, bacterial characteristics, drug resistance status in patients with urinary tract infections treated at Department of Urology, Hue University Hospital. Materials and Method: The study was conducted in 474 patients with urological disease treated at Department of Urology, Hue Universiry Hospital from July 2017 to April 2018. Urine culture was done in the patients with urine > 25 Leu/ul who have symptoms of urinary tract disease or infection symptoms. Patients with positive urine cultures were analyzed for clinical and bacterial characteristics. Results: 187/474 (39.5%) patients had symptoms associated with urinary tract infections. 85/474 (17.9%) patients were diagnosed with urinary tract infection. The positive urine culture rate was 45.5%. Symptoms of UTI were varied, and no prominent symptoms. E. coli accounts for the highest proportion (46.67%), followed by, Staphycoccus aureus (10.67%), Pseudomonas aeruginsa (8,0%), Streptococcus faecali and Proteus (2.67%). ESBL - producing E. coli was 69.23%, ESBL producing Enterobacter spp was 33.33%. Gram-negative bacteria are susceptible to meropenem, imipenem, amikacin while gram positive are vancomycin-sensitive. Conclusions: Clinical manifestations of urinary tract infections varied and its typical symptoms are unclear. E.coli is a common bacterium (46.67%). Isolated bacteria have a high rate of resistance to some common antibiotics especially the third generation cephalosporins and quinolones. Most bacteria are resistant to multiple antibiotics at the same time. Gram (+) bacteria are susceptible to vancomycin, and gram (-) bacteria are susceptible to cefoxitin, amikacin, and carbapenem. Key words: urinary tract infection

scholarly journals Measuring Antibiotic Appropriateness for Urinary Tract Infections in Nursing Home Residents

2017 ◽  
Vol 38 (8) ◽  
pp. 998-1001 ◽  
Author(s):  
Taniece Eure ◽  
Lisa L. LaPlace ◽  
Richard Melchreit ◽  
Meghan Maloney ◽  
Ruth Lynfield ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Nursing Home ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Nursing Home Residents ◽  
Infect Control Hosp ◽  
Antibiotic Prescribing ◽  
Appropriate Use ◽  
Tract Infections

We assessed the appropriateness of initiating antibiotics in 49 nursing home (NH) residents receiving antibiotics for urinary tract infection (UTI) using 3 published algorithms. Overall, 16 residents (32%) received prophylaxis, and among the 33 receiving treatment, the percentage of appropriate use ranged from 15% to 45%. Opportunities exist for improving UTI antibiotic prescribing in NH.Infect Control Hosp Epidemiol 2017;38:998–1001

Circumcision and Urinary Tract Infections

PEDIATRICS ◽  
1986 ◽  
Vol 77 (2) ◽  
pp. 267-269
Author(s):  
THOMAS E. WISWELL
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
First Year ◽  
Tract Infections ◽  
First Year Of Life

In Reply.— Dr Cunningham apparently believes that there is no plausible physiologic explanation for the association between a decreased incidence of urinary tract infections and circumcisions as we recently described,1 and that we should seek alternative explanations for our findings. However, we disagree with most of the alternative suggestions and the comments that he has made. We recently completed a second study evaluating the occurrence of urinary tract infections during the first year of life in more than 400,000 infants.

Diagnosis of Urinary Tract Infection

PEDIATRICS ◽  
1972 ◽  
Vol 50 (6) ◽  
pp. 975-975
Author(s):  
James Kennedy Todd
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
False Positives ◽  
Colony Count ◽  
Tract Infections

The recent paper by Cohen in the August issue of Pediatisics relies on the use of "one or more cultures of over 100,000 organisms per millimeter of urine" to make the diagnosis of urinary tract infections upon which the remainder of the study is dependent. Obviously, the colony count was intended to read "per milliliter," and yet the results of the study must be seriously questioned since the criterion for diagnosis of urinary tract infection was not rigid enough to exclude a large number of false-positives— patients who never really had urinary tract infections.

Sign in / Sign up

Export Citation Format

Share Document