Chlamydia and Suspected Sexual Abuse

PEDIATRICS ◽  
1988 ◽  
Vol 81 (4) ◽  
pp. 601-602
Author(s):  
LAWRENCE S. NEINSTEIN ◽  
C. DANIEL FUSTER
Keyword(s):  
Sexual Abuse ◽  
Child Abuse ◽  
Young Child ◽  
Sensitivity And Specificity ◽  
Fluorescent Antibody ◽  
Antibody Test ◽  
Prevalence Rates ◽  
Perinatal Infection ◽  
Direct Fluorescent Antibody ◽  
Low Prevalence

In Reply.— We thank Dr Hammerschlag for her thoughtful comments. We wholeheartedly agree with her about the use of cultures in the setting of suspected sexual abuse. As other studies have indicated, the sensitivity and specificity of the direct fluorescent antibody test are too low in a population with low prevalence rates such as a population with suspected child abuse. We also agree with Dr Hammerschlag about the possibility of perinatal infection in a young child.

Child Abuse

PEDIATRICS ◽  
1990 ◽  
Vol 86 (5) ◽  
pp. 805-806
Author(s):  
ALLAN R. DE JONG ◽  
MIMI ROSE
Keyword(s):  
Sexual Abuse ◽  
Child Abuse ◽  
Sensitivity And Specificity ◽  
Gold Standard ◽  
Child Protective Services ◽  
Iron Pyrite ◽  
Protective Services ◽  
Physical Evidence

In Reply.— We thank Dr Smith for his interesting perspective regarding screening for child abuse. We had hoped our article would help physicians focus on the verbal evidence of abuse and show how insensitive the physical evidence is in predicting which child had been abused sexually. To apply the principles of sensitivity and specificity to the assessment of child abuse or sexual abuse, we must have a gold standard which characterizes these problems. Neither a child protective services decision nor a legal determination of "no proven abuse" can be used as a gold standard, unless we can accept a "gold standard" made of iron pyrite.

scholarly journals A Comparative Analysis of Polymerase Chain Reaction and Direct Fluorescent Antibody Test for Diagnosis of Genital Herpes

2017 ◽  
Vol 9 (01) ◽  
pp. 053-056 ◽  
Author(s):  
Vrushali Patwardhan ◽  
Preena Bhalla ◽  
Deepti Rawat ◽  
Vijay Kumar Garg ◽  
Kabir Sardana ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Genital Herpes ◽  
Fluorescent Antibody ◽  
Antibody Test ◽  
Conventional Polymerase Chain Reaction ◽  
Genital Ulcer ◽  
Chain Reaction ◽  
Direct Fluorescent Antibody ◽  
Polymerase Chain ◽  
Simplex Virus

ABSTRACT Objective: To compare laboratory tests that can simultaneously detect and type herpes simplex virus (HSV) directly from the genital ulcer specimens in clinically suspected cases of genital herpes. Materials and Methods: A study was conducted over 10 months and 44 adult male and female patients clinically suspected with genital herpes were recruited. Genital ulcer swab specimens were subjected to glycoprotein-G gene-based conventional polymerase chain reaction (PCR) and commercially available direct fluorescent antibody (DFA) test and the results were compared. Results: PCR for HSV was positive in 82% (36/44) cases. DFA was positive in 68.2% (30/44) cases. There was 100% agreement between HSV types detected by DFA and PCR. The strength of agreement between the results was better in primary genital herpes than recurrent cases. Conclusion: PCR was found to be better in the detection of HSV in recurrent genital herpes patients. It is a better modality, especially when genital herpes clinically presents with ulcerative or crusted lesions, and is also a cheaper alternative as compared to DFA.

Evaluation of the direct fluorescent antibody test for diagnosis of chlamydial infections

1985 ◽  
Vol 4 (6) ◽  
pp. 548-552 ◽  
Author(s):  
K. H. Tjiam ◽  
R. V. W. van Eijk ◽  
B. Y. M. van Heijst ◽  
G. J. Tideman ◽  
Th. van Joost ◽  
...  
Keyword(s):  
Fluorescent Antibody ◽  
Antibody Test ◽  
Direct Fluorescent Antibody ◽  
Chlamydial Infections
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