Maternal Risks for Very Low Birth Weight Infant Mortality

PEDIATRICS ◽  
1996 ◽  
Vol 98 (2) ◽  
pp. 236-241
Author(s):  
Tracey Sumits ◽  
Robert Bennett ◽  
Jeffrey Gould
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Infant Mortality ◽  
Low Birth Weight ◽  
Infant Death ◽  
Very Low Birth Weight ◽  
Maternal Risk Factors ◽  
Low Birth Weight Infants ◽  
Maternal Risk ◽  
Planned Pregnancy

Objective. To determine whether known maternal risk factors for low birth weight directly contribute to infant mortality among very low birth weight infants. Design. Retrospective population-based, case-control study. Setting. Four hospitals in the Oakland, California, area: one community, two private, one health maintenance organization. Participants. All live-born singleton very low birth weight (<1500 g) infants born to Oakland residents over a 3-year period. Cases were infants who died before their first birthday, identified by computerized linkage of birth and death certificates. For each case, a surviving control was selected to match for birth weight, sex, and race. Forty matched pairs were identified in total. Outcome Measures. Prevalence of maternal risk factors among cases versus controls. Results. After controlling for other factors known to influence either birth weight or infant mortality, maternal cocaine use (odds ratio [OR] = 5.43), prior infant death (OR = 27.14), and planned pregnancy (OR = 6.33) were significantly associated with the survival of very low birth weight infants. Conclusions. Some maternal risk factors for low birth weight confer a survival advantage to very low birth weight infants. Our data reveal that maternal cocaine use is independently associated with survival among this subset of infants. Prior research supports the observed relationship as well as the scientific plausibility of a cocaine-mediated survival advantage among premature infants. Our study also showed both planned pregnancy and prior infant death to be independently associated with infant survival among this subset of infants, sugesting that maternal behaviors may play a role in determining birth weight-specific mortality. These data should be systematically evaluated to better define their relationship to infant mortality.

scholarly journals Study on prevalence of maternal risk factors, morbidity and mortality in very low birth weight neonates

2021 ◽  
Vol 8 (6) ◽  
pp. 1027
Author(s):  
Ujjwala S. Keskar ◽  
Anjali H. Parekh
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Antenatal Steroids

Background: Very low birth weight babies with respiratory complications are the commonest reason for admission in NICU. We wanted to identify maternal risk factors associated with it and ways to prevent it. The objective of the current study was to study the prevalence of maternal risk factors, morbidity and mortality in VLBW babies admitted in tertiary care hospital NICU.Methods: Cross sectional observational study performed on all very low birth weight (VLBW) neonates admitted in neonatal intensive care unit of tertiary care hospital attached with Smt. Kashibai Navale medical college, Pune from January 2019 to March 2020.Results: In our study VLBW babies were 2.2% (78/3545). Mean gestational age was 31.15±3.21 weeks; mean birth weight was 1226.24±250.95 grams. Small for gestational age (SGA) babies were 41% and 96% were preterm. Maternal risk factors were present in 61.53% of deliveries, commonest were anaemia in 30.06 % and preeclampsia in 24.35%. Resuscitation at birth was required in 30.76% babies. Morbidity profile showed respiratory distress syndrome in 46.15%, neonatal sepsis in 19.23% and patent ductus arteriosus in 16.66% babies. Overall survival was 74.35%. Prematurity and its complications like RDS requiring surfactant therapy and mechanical ventilation were significant contributors for mortality but only 23.07% mothers were found to have received antenatal steroids in the hospital .Conclusions: Anaemia and preeclampsia were commonly found risk factors present in 61.53% of mothers of VLBW babies. Use of antenatal steroids in mothers should be made compulsory to decrease mortality in VLBW preterm newborns.

scholarly journals Maternal Risk Factors and Morbidity Pattern of Very Low Birth Weight Infants: A NICU Based Study at Eastern Nepal

2009 ◽  
Vol 29 (2) ◽  
pp. 59-66 ◽  
Author(s):  
Prakash Poudel ◽  
Sunil Budhathoki ◽  
Manoj Kumar Shrivastava
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Ductus Arteriosus ◽  
Pregnancy Induced Hypertension ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Factors Associated ◽  
Induced Hypertension

Background: Preterm deliveries of babies weighing less than 1500 grams (VLBW, very low birth weight) are of major concern because of maximum perinatal morbidity and mortality found in this group. VLBW babies overload the neonatal intensive care unit (NICU) and their mortality contributes significantly to neonatal and infant mortality. Objectives: To study the common maternal risk factors associated with VLBW births. To study the morbidity and mortality patterns of VLBW babies. Methods: This was a hospital based retrospective study done in NICU of BP Koirala Institute of Health Sciences. Data were collected from medical records of VLBW babies admitted in NICU over a period of three years (13 April 2005 to 12 April 2008). Data were analyzed with SPSS 10.0 software. Results: Data of 140 VLBW babies were analyzed. Mean birth weight was 1188.9 (±212.78), 10.7% were home deliveries, 24.3% were twins, 31.4% required active resuscitation at birth and 46.4% were exposed to antenatal steroid. Common maternal risk factors associated with premature deliveries were inadequate antenatal check up (ANC) visits (95.7%), twin pregnancy (24.3%), antepartum hemorrhage (APH, 28.6%), premature rupture of membrane (23.6%), pregnancy induced hypertension (12.9%), bad obstetric history (12.9%) and maternal age less than 20 years (8.6%). Common morbidities among VLBW babies were clinical sepsis (77.1%), non physiological hyperbilirubinemia (73.6%), apnea (48.6%), shock (42.9%), hypoglycemia(39.3%), anemia (29.3%), hyaline membrane disease (HMD, 21.4%), patent ductus arteriosus (15.0%), severe hypothermia (12.1%), culture proven sepsis (15.7%), retinopathy of prematurity (5.7%), and bronchopulmonary dysplasia (3.6%). Overall survival was 54.3% and major causes of death were HMD (51.0%) and sepsis (34.7%). Median durations of hospital stay were 17.5 days for survivors and five days for expired cases.Conclusion: Increasing the coverage of ANC visits, early diagnosis and treatment of APH and pregnancy induced hypertension, discouraging the childbirth at too young age, early diagnosis and treatment of acute infections and chronic medical diseases in mothers are important measures to decrease the burden of VLBW births. Common morbidities in VLBW babies are sepsis, HMD, apnea, hyperbilirubinemia, patent ductus arteriosus, shock, anemia, hypoglycemia, hypothermia and hypocalcemia. Common causes death of VLBW babies are HMD and sepsis. Overall survival of VLBW babies in our settings is less. More numbers of well equipped NICUs and services like surfactant therapy are needed to improve survival of VLBW infants in our set up. Key words: Maternal risk factors, Morbidity, Mortality, Very low birth weight.   doi: 10.3126/jnps.v29i2.2040 J. Nepal Paediatr. Soc. Vol 29, No. 2, pp.59-66

scholarly journals Risk Factors and Outcomes of Low Birth Weight Neonates Admitted In a Tertiary Care Center

2020 ◽  
Vol 18 (1) ◽  
pp. 70-73
Author(s):  
Jyoti Adhikari ◽  
Rajesh KC ◽  
Shristi Kharel
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Sepsis ◽  
Very Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
Antenatal Visit ◽  
High Morbidity ◽  
Maternal Risk Factors ◽  
Maternal Risk

Introduction: Birth weight <2500 grams, <1500 grams and <1000 grams irrespective of gestational age is low birth weight, very low birth weight and extremely low birth weight respectively. Low birth weight is associated with high morbidity and mortality. Aims: To find out the possible maternal risk factors associated with low birth weight babies, morbidities and mortalities seen in them during their hospital stay. Methods: Hospital based cross sectional observational study was performed in 200 newborns <2500 grams in Nepalgunj Medical College, Kohalpur, Banke, Nepal. Results: Out of 200 neonates 8 (4%), 40 (20%) and 152 (76%) were extremely low birth weight, very low birth weight and low birth weight respectively with Male:Female ratio of 1.12:1. Most common maternal risk factors for low birth weight was Illiterate mothers (88%) followed by preterm delivery (68%). Inadequate antenatal visit was associated with low birth weight (P<0.05). Most common morbidity seen in low birth weight was neonatal sepsis (96%) followed by neonatal jaundice (87%). 44 (22.0%) neonates expired and 156 (78.0%) survived. Neonatal sepsis was most common (36.4%) cause of mortality followed by respiratory distress syndrome (22.7%). Conclusion: Certain measures could be taken to prevent low birth weight deliveries: discouraging delivery at teenage, adequate antenatal visits, avoiding smoking and alcohol during pregnancy. Well trained staffs and better facilities in neonatal intensive care unit could improve the survival and minimize the morbidities in low birth neonates.

scholarly journals P2-445 Maternal risk factors associated with low birth weight in Wardha, India

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A344-A344
Author(s):  
C. Maliye ◽  
M. Taywade ◽  
S. Gupta ◽  
P. Deshmukh ◽  
B. Garg
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Factors Associated

scholarly journals Maternal Risk Factors, Clinical Profile and Short-Term Outcome of Pre-Term Low Birth Weight Babies

KYAMC Journal ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 77-82
Author(s):  
Mosammat Afroza Jinnat ◽  
Shafi Ahmed ◽  
Sirajum Monira ◽  
Muhammad Mozammel Haque ◽  
Mashura Musharraf ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Maternal Risk Factors ◽  
Short Term ◽  
Term Outcome ◽  
Maternal Risk ◽  
Short Term Outcome ◽  
Low Birth Weight Babies ◽  
Neonatal Ward

Background: Preterm Low Birth Weight babies carry relatively higher risk of perinatal and neonatal mortality, retarded growth and development subsequently. In this study, some maternal risk factors were investigated as it seems to be important to study these factors on regional basis. Objective: To find out the maternal risk factors, clinical profile and short term outcome of pre-term low birth weight neonates by gestational age, birth weight, Occipitofrontal Circumference, length, different presentation (asphyxia, hypothermia, feeding difficulties, signs of infection) on admission and the morbidity and mortality of preterm LBW. Materials and Methods: A descriptive type of cross sectional study was done in neonatal ward of Jalalabad Ragib Rabeya Medical College Hospital, Sylhet from May, 2015 to April, 2016. Hundred cases were selected from neonatal ward and 100 controls were selected from obstetrics ward. Results: Among 100 pre-term LBW neonates, 52 were male and 48 were female. Only 22% mother took regular antenatal check up in case group and 55% in control group. Mean gestational age of neonates were 33.3±2.1 weeks. Important risk factors were primi parity (58% in cases vs 34% in control), hypertension (19% vs 5%), pre-eclampsia (26% vs 12%), prolonged rupture of membrane (33% vs 7%), APH (22% vs 0%), acute infection (8% vs 1%), multiple birth (17% vs 2%). Common clinical presentations were prematurity and LBW. Commonest morbidity was feeding problem (70%). The overall survival rate was 87%. Most common cause of death was septicemia (30%). Conclusion: all the identified risk factors were significantly higher in pre-term LBW babies than those of control. KYAMC Journal Vol. 11, No.-2, July 2020, Page 77-82

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