scholarly journals Histopathological changes in pigs infected with ileitis

2020 ◽  
Vol 10 (4) ◽  
pp. 72-77
Author(s):  
O.M. Yermolenko ◽  
O.Y. Ayshpur ◽  
I.Yu. Mushtuk
Keyword(s):  
Histological Examination ◽  
Severe Disease ◽  
Gastrointestinal Diseases ◽  
Pathological Changes ◽  
Histopathological Changes ◽  
Lawsonia Intracellularis ◽  
Early Diagnostics ◽  
Chronic Effect ◽  
Anatomical Changes ◽  
Proliferative Enteropathy

Nowadays, the ileitis (proliferative enteropathy of pigs) is one of the most common gastrointestinal diseases. The intracellular bacterium Lawsonia intracelluaris causes several forms of the disease. Histological examinations are the important stages in diagnosing and detecting profound pathological changes in sick pig organs, decreasing their productivity and causing the deaths. Swine proliferative enteropathy (SPE) has reported for the Ukraine since 2008. For SPE the early diagnostics with different test systems is relevant. We evaluated the sick, forcibly killed and dead piglets of different ages in Ukrainian pig farms during 2018-2019 in animal fattening groups. Materials were taken from piglets aged 120-150 days in farms where the ileitis was diagnosed. To assess the complex of pathological and anatomical changes detected during autopsies of piglets, V.P. Shishkov’s methods were used. Thus, we revealed a characteristic morphology of proliferative lesions. We believed that the histological examination can serve as an important diagnostic method and an alternative to direct isolation of Lawsonia intracellularis, which is very difficult to cultivate. We determined that the histopathological changes in pig organs indicated a chronic effect caused by animal pathogen. We revealed that Lawsonia intracellularis caused the profound pathological changes in pig digestive tracts, which affected the functioning of all organs and tissues of animals and lead to severe disease and possible animal death. We suggested that the histological examination is an important step in diagnosing and detecting profound pathological changes in the organs of sick pigs, which caused the decrease in their productivity and deaths.

Relationship between the severity of porcine proliferative enteropathy and the infectious dose of Lawsonia intracellularis

2003 ◽  
Vol 153 (14) ◽  
pp. 432-433 ◽  
Author(s):  
R. M. C. Guedes ◽  
N. L. Winkelman ◽  
C. J. Gebhart
Keyword(s):  
Lawsonia Intracellularis ◽  
Infectious Dose ◽  
Proliferative Enteropathy

scholarly journals Draft Genome Sequence of Lawsonia intracellularis Strain E40504, Isolated from a Horse Diagnosed with Equine Proliferative Enteropathy

2017 ◽  
Vol 5 (19) ◽  
Author(s):  
Nandita S. Mirajkar ◽  
Molly R. Kelley ◽  
Connie J. Gebhart
Keyword(s):  
Genome Sequence ◽  
Genomic Island ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Lawsonia Intracellularis ◽  
Protein Coding ◽  
Content Type ◽  
Obligate Intracellular ◽  
Proliferative Enteropathy ◽  
Rna Genes

ABSTRACT Reported herein is the draft genome sequence of equine-origin Lawsonia intracellularis strain E40504, an obligate intracellular bacterium and the etiological agent of equine proliferative enteropathy. The 1.69-Mb draft genome sequence includes 1,380 protein-coding genes and 49 RNA genes, and it lacks a genomic island reported in swine-origin L. intracellularis strain PHE/MN1-00.

scholarly journals Abdominal syndrome in pulmonary tuberculosis

2021 ◽  
Vol 30 (9) ◽  
pp. 839-843
Author(s):  
N. M. Zakharov
Keyword(s):  
Gastrointestinal Tract ◽  
Pulmonary Tuberculosis ◽  
Digestive System ◽  
Diagnostic Errors ◽  
Gastrointestinal Diseases ◽  
The Other ◽  
Gastrointestinal Disorders ◽  
System Function ◽  
Anatomical Changes ◽  
The Subject

A large number of works that have appeared in recent years in our and foreign literature on the subject of tuberculous intestinal diseases can be explained mainly by the exceptional importance of the gastrointestinal tract behavior in tbc patients and, on the other hand, by the frequency of this suffering. Most of these works concern the clinic of tuberculous lesions of the intestine with a definite pathological and anatomical substrate at the base. However, disorders of digestive system function in patients with pulmonary tuberculosis can occur without the presence of any anatomical changes and dyspeptic disorders observed in these cases, extremely diverse in their clinical picture, not seldom present exceptional difficulty in recognizing the true causes of gastrointestinal disorders. Passing under the mask of a variety of gastrointestinal diseases, they can give rise to diagnostic errors.

A testudinid herpesvirus 1 (TeHV1)-associated disease outbreak in a group of Horsfield’s tortoises (Testudo horsfieldii)

2021 ◽  
Vol 49 (06) ◽  
pp. 462-467
Author(s):  
Lisa Schüler ◽  
Pierre Picquet ◽  
Christoph Leineweber ◽  
Janosch Dietz ◽  
Elisabeth Müller ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Histological Examination ◽  
Inclusion Bodies ◽  
Severe Disease ◽  
Disease Outbreak ◽  
High Morbidity ◽  
Intranuclear Inclusion ◽  
Upper Respiratory ◽  
Herpesvirus 1 ◽  
Mycoplasma Spp

AbstractIn spring 2020, a severe disease outbreak with high morbidity and mortality was observed in a collection of 15 Horsfield’s tortoises (Testudo horsfieldii). Affected tortoises showed upper respiratory- and gastrointestinal tract signs, including rhinitis and stomatitis. Testudinid herpesvirus 1 (TeHV1) and Mycoplasma spp. were detected by PCR in oral swabs of affected animals. Histological examination of one deceased animal showed intranuclear inclusion bodies typical for herpesvirus infections in liver, spleen and oesophagus. The virus was likely introduced into the collection 2 years earlier by a clinically healthy Horsfield’s tortoise that was tested positive for TeHV1 by PCR.

scholarly journals Tylosin injectable for the treatment of porcine proliferative enteropathy in experimentally inoculated pigs

2019 ◽  
Vol 39 (3) ◽  
pp. 168-174
Author(s):  
Luisa V.A. Otoni ◽  
Michelle P. Gabardo ◽  
Núbia R. Macêdo ◽  
Mariane M. Wagatsuma ◽  
Marina M. Pereira ◽  
...  
Keyword(s):  
Body Condition Score ◽  
Initial Period ◽  
Etiologic Agent ◽  
Economic Losses ◽  
Control Group ◽  
Lawsonia Intracellularis ◽  
Medication Group ◽  
Proliferative Enteropathy ◽  
Condition Score ◽  
And Control

ABSTRACT: Porcine proliferative enteropathy (PPE) is one of the most common enteric diseases in growing and finishing pigs. PPE is characterized by reduced growth performance, accompanied or not by diarrhea. PPE is highly prevalent in several countries of the Americas, Europe and Asia, causing high economic losses in swine herds. The most common form of PPE control in pigs is antibiotic therapy. The objective of this study was to evaluate a new product based on tylosin injectable (Eurofarma Laboratórios S.A.) to control PPE in experimentally inoculated animals. Sixty 5-week-old pigs with mean weight of 9.5kg were divided into two experimental groups of 30 animals: medication and control. All pigs were challenged with Lawsonia intracellularis, the etiologic agent of PPE, on day zero. Fecal score, body condition score, and behavior were daily evaluated. Pigs were weighted on days -2, 13 and 21 of the experiment. Pigs in the Medication Group received tylosin injectable 13 days after inoculation, in three doses with a 12-hour interval between them. Pigs in the Control Group received injectable saline solution following the same protocol. In the Control Group, 23pigs presented with diarrhea before day 13. After day 13, the number of diarrheic animals in this group was reduced to 17. In the Medication Group, 26 pigs presented with diarrhea in the initial period, and in the period after medication, only 11 animals had diarrhea. The score of gross intestinal PPE lesions in the Medication Group was lower than that in the Control Group (p=0.031). The Medication Group also showed lower score for Lawsonia intracellularis antigen-labeling by immunohistochemistry compared with that of the Control Group (p=0.032), showing lower level of infection. These results demonstrate that tylosin injectable (Eurofarma Laboratórios S.A.), administrated in three doses (1mL/20kg) every 12 hours, was effective for the control of PPE in experimentally inoculated pigs.

scholarly journals Histopathological changes in gallbladder mucosa associated with cholelithiasis

1970 ◽  
Vol 2 (3) ◽  
pp. 224-225 ◽  
Author(s):  
R Baidya ◽  
B Sigdel ◽  
NL Baidya
Keyword(s):  
Retrospective Study ◽  
Intestinal Metaplasia ◽  
Gastrointestinal Disorder ◽  
Gallstone Formation ◽  
Epithelial Hyperplasia ◽  
Pathological Changes ◽  
Histopathological Changes ◽  
Gallbladder Epithelium ◽  
Gallbladder Mucosa ◽  
Gross Examination

Background: Gallstone is a very common gastrointestinal disorder. It is known to produce histopathological changes in the gallbladder. It is also one of the predisposing factors for the development of cancer of gallbladder. Materials and Methods: This was a retrospective study carried out in the Department of Histopathology, B and B Hospital during a period of 1 year from April 2010 to May 2011. The study included 396 cases of cholecystectomy specimens. Results: On gross examination, outer gallbladder surface was congested in 116 patients (28%), wall thickness was increased in 181 (45.7%) and mucosal abnormalities were present in 126 (31.6%) patients. At microscopy, epithelial hyperplasia was observed in 183 (46.2%), intestinal metaplasia in 112 (28.2%), dysplasia in 5 (1.3%) and cholesterolosis in 56 (14%) patients. Conclusion: The pathological changes of the gallbladder epithelium may play an important role in the process of gallstone formation. DOI: http://dx.doi.org/10.3126/jpn.v2i3.6027 JPN 2012; 2(3): 224-225

scholarly journals Isolation of Lawsonia intracellularis in Korea and Reproduction of Proliferative Enteropathy in Pigs and Hamsters

2006 ◽  
Vol 68 (5) ◽  
pp. 499-501 ◽  
Author(s):  
Jung-Yong YEH ◽  
Tae-Jong KIM ◽  
Seung-Yong PARK ◽  
Chang-Seon SONG ◽  
Yong-Dhuk YOON ◽  
...  
Keyword(s):  
Lawsonia Intracellularis ◽  
Proliferative Enteropathy

Detection of Lawsonia intracellularis in the tonsils of pigs with proliferative enteropathy

2000 ◽  
Vol 68 (1) ◽  
pp. 23-26 ◽  
Author(s):  
T.K. JENSEN ◽  
K. MØLLER ◽  
R. LINDECRONA ◽  
S.E. JORSAL
Keyword(s):  
Lawsonia Intracellularis ◽  
Proliferative Enteropathy

scholarly journals Failure of Added Dietary Gluten to Induce Small Intestinal Histopathological Changes in Patients with Watery Diarrhea and Lymphocytic Colitis

1996 ◽  
Vol 10 (7) ◽  
pp. 436-439 ◽  
Author(s):  
Hugh James Freeman
Keyword(s):  
Celiac Disease ◽  
Small Bowel ◽  
Microscopic Colitis ◽  
Lymphocytic Colitis ◽  
Watery Diarrhea ◽  
Pathological Changes ◽  
Histopathological Changes ◽  
Proximal Small Bowel ◽  
Colorectal Biopsies ◽  
Small Intestinal

Lymphocytic colitis is a form of microscopic colitis usually characterized by watery diarrhea and often associated with biopsy-defined celiac disease. Two patients with lymphocytic colitis and normal small intestinal biopsies who were administered 40 g of added dietary gluten for four consecutive weeks are presented. Small intestinal biopsies from multiple sites in the proximal small bowel were done after three and four weeks to determine whether pathological changes in latent celiac disease could be induced in these patients with a high gluten-containing diet. In addition, colorectal biopsies were done to determine whether the colitis was sensitive to oral gluten. No alterations in the small intestinal biopsies were detected in either patient and no changes occurred in colitis severity. Although microscopic forms of colitis have been linked to celiac disease, this study indicates that lymphocytic colitis is a heterogeneous clinicopathological disorder that, in some patients, is independent of any gluten-induced intestinal pathological changes.

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