scholarly journals Pathomorphological diagnostics of enteritis of viral etiology in dogs

2018 ◽  
Vol 20 (83) ◽  
pp. 299-303 ◽  
Author(s):  
V. Lisova ◽  
N. Radsikhovskii
Keyword(s):  
Small Intestine ◽  
Mucous Membrane ◽  
Lymphoid Tissue ◽  
Histological Structure ◽  
Regional Lymph Nodes ◽  
Mesenteric Lymphadenitis ◽  
Morphological Criteria ◽  
Liver And Kidney ◽  
Coronavirus Infection ◽  
Pathological Material

The article presents the results of the study of pathomorphological changes in organs and tissues of dogs at parvovirus and coronavirus infections. The pathoanatomical section and histological examination of pathological material selected from cadavers of dogs of different breeds and sex between 2 to 6 months who died with signs of infectious diarrhea were conducted. Pathomorphological study was performed only on cadavers of animals in which the life using PCR in stool specimens was established clinical diagnosis – parvovirus enteritis (n = 13) and coronavirus enteritis (n = 7). After selection of the pathological material, it was immediately fixed in a 10% aqueous solution of neutral formalin followed by pouring into a sealing medium (paraffin). The obtained histological sections were stained with hematoxylin and eosin according to standard prescriptions. The general histological structure and microstructural changes in histological preparations were studied under a light microscope. Histological studies have been confirmed and supplemented with pathoanatomical diagnoses, established after autopsies of bodies of dead animals. The most pronounced lesions and typical change in all dead dogs fixed contact in the small intestine (jejunum and to the ileum) and the regional lymph nodes. In addition, in the case of coronavirus infection, changes in the spleen are detected. According to the results of our study, the morphological criteria, on which the pathomorphological diagnosis of parvovirus infection in dogs is based include: hemorrhagic jejuno-ileitis; hemorrhage in the serous and mucous membrane of the small intestine; hemorrhagic mesenteric lymphadenitis; depletion and necrosis of lymphoid tissue. It is shown that the morphological manifestations of coronavirus infection in the dead dogs are with the following signs: the presence of exudative inflammation in the small intestine in the form serous-catarrhal or serous-fibrinous jejuno-ileitis; hyperplasia of single and congested lymphoid nodes of the mucous membrane of the small intestine; hyperplasia and serous-hemorrhagic mesenteric lymphadenitis; hemorrhagic infarcts in the spleen parenchyma; hyperplasia of lymphoid tissue; hemorrhage in the serous membrane of the small intestine; dehydration. Not typical, but constant morphological signs of enteritis, which arose as a result of circulatory disorders and heart failure were: passive venous congestion of the liver and kidney; degenerative processes in the liver and kidney parenchyma; pulmonary edema.

scholarly journals Гістологічні зміни в собак за коронавірусної інфекції

2017 ◽  
Vol 19 (78) ◽  
pp. 154-157 ◽  
Author(s):  
V. Lisova ◽  
O. Dubinenko
Keyword(s):  
Small Intestine ◽  
Lymph Nodes ◽  
Histological Study ◽  
Polymerase Chain Reaction Analysis ◽  
Histological Structure ◽  
Mesenteric Lymph Nodes ◽  
Regional Lymph Nodes ◽  
Liver And Kidney ◽  
Coronavirus Infection ◽  
Pathological Material

The article presents the results of the study of histological changes in organs and tissues of dogs for coronavirus infection. The histological study of the pathological material of cadavers (n =5) dogs of different breeds and sex between the ages of 2 to 6 months, who died with diarrheal syndrome. The study of presence of coronavirus, without other assiociants, in these cases had previously been confirmed in the polymerase chain reaction analysis of fecal samples. The made histological sections were stained with hematoxylin and eosin according to standard prescriptions. The general histological structure and microstructural changes in histological preparations were studied under a light microscope. Histological studies have been confirmed and supplemented with pathoanatomical diagnoses, established after autopsies of dead bodies of dead animals. The most pronounced lesions and typical change in all dead dogs fixed contact in the small intestine (jejunum and to the ileum) and the regional lymph nodes to it, as well as in the spleen. It is shown that the morphological manifestations of coronavirus infection in dogs following features are on the microscopic level: the presence of exudative inflammation in the small intestine in the form serous-fibrinous jejuno-ileitis; hyperplasia of single and congested lymphoid nodes of the mucous membrane of the small intestine; hyperplasia and serous-hemorrhagic lymphadenitis mesenteric lymph nodes; foci of hemorrhage and hemorrhagic heart attacks in the spleen parenchyma; hyperplasia lymphoid nodes of the spleen; foci of hemorrhage in the serous membrane of the small intestine. Also, non-specific, but constant morphological features, which arose as a result of circulatory disorders and heart failure were: passive venous congestion of the liver and kidney; degenerative processes in the liver and kidney parenchyma. Consequently, local and general immunological processes develop during the coronaviral infection. Therefore, additional diagnostic markers appear hyperplastic and inflammatory changes of regional seats to the reproduction of the virus lymphoid organs.

scholarly journals Патоморфологічна характеристика коронавірусної інфекції в собак

2017 ◽  
Vol 19 (77) ◽  
pp. 7-10
Author(s):  
V. Lisova ◽  
O. Dubinenko
Keyword(s):  
Small Intestine ◽  
Lymph Nodes ◽  
Polymerase Chain Reaction Analysis ◽  
Underlying Disease ◽  
Left Ventricular ◽  
Morphological Features ◽  
Mesenteric Lymph Nodes ◽  
Regional Lymph Nodes ◽  
Coronavirus Infection ◽  
Pathological Material

The results of the study of the morphological features of pathological processes in organs and tissues of dogs with coronavirus infection. The study of cadavers (n = 3) dogs of different breeds and sex between the ages of 2 to 6 months, who died with diarrheal syndrome. Presence of coronavirus, without other assiociants, in these cases had previously been confirmed in the polymerase chain reaction analysis of fecal samples. At this stage, the main method of our study was mortem autopsy. At autopsy, which was carried out in partial evisceration, recorded and described the macroscopic changes identified in various tissues and organs of dead dogs and selected pathological material for subsequent histological examination. It is shown that the most pronounced lesions and typical change in all dead dogs fixed contact in the small intestine (jejunum and to the ileum) and the regional lymph nodes to it, as well as in the spleen. It is shown that the morphological manifestations of coronavirus infection in dogs following features are on the macroscopic level: the presence of exudative inflammation in the small intestine in the form serous-fibrinous jejuno-ileitis; hyperplasia and serous-hemorrhagic lymphadenitis mesenteric lymph nodes; multiple foci of hemorrhage of different character (spotted and striped) in the parenchyma of the spleen and serous membrane of the small intestine; dilatation of the right ventricle of the heart; cachexy and dehydration due to diarrheal syndrome. Also, non-specific, but constant morphological features, which arose as a result of circulatory disorders and heart failure were: passive venous congestion of the liver, kidney and pulmonary edema; degenerative processes in the liver. In one case, we identified morphological features characteristic of serous-inflammatory swelling of the pancreas and pathological changes in the myocardium that are typical of concentric hypertrophy of left ventricular heart. These pathological processes can be considered a complication that developed as a result of the underlying disease.

scholarly journals Гістологічні зміни в котів за хламідіозу

2017 ◽  
Vol 19 (78) ◽  
pp. 158-161
Author(s):  
V. Lisova ◽  
A. Savchenko
Keyword(s):  
Lymph Nodes ◽  
Interstitial Pneumonia ◽  
Chlamydial Infection ◽  
Histopathological Examination ◽  
Clinical Manifestations ◽  
Bronchial Epithelium ◽  
Histological Structure ◽  
Regional Lymph Nodes ◽  
Morphological Criteria ◽  
Hematoxylin And Eosin

The article presents the results of the study of histological changes in organs and tissues of cats for chlamydial infection. The histopathological examination of the postmortem cases of cats (n = 8) of different breeds between the ages of 3 to 6 years old, who lives with the laboratory methods have been diagnosed and identified the pathogen Chlamydia felis. According to historical data from sick animals were recorded various nature and degree of conjunctivitis and pronounced signs of a lesion of the respiratory tract (rhinitis, bronchitis, pneumonia). The made histological sections were stained with hematoxylin and eosin according to routine standard methods. The general histological structure and microstructural changes in histological preparations were studied under a light microscope. The histopathological examination were confirmed and specified the pathoanatomical diagnoses, established after autopsy of dead animals. It is shown that the most pronounced damage and characteristic changes all dead cats fixed contact in lung tissues and regional lymph nodes (mediastinal and bronchial), and in the spleen. The morphological criteria of chlamydial infection in the studied dead animals at the microscopic level were as follows:1) interstitial pneumonia; 2) pulmonary fibrosis; 3) fibrinous-purulent pleuropneumonia; 4) hyperplasia and serous lymphadenitis of the mediastinal and bronchial lymph nodes; 5) hyperplasia of lymphoid nodules of the spleen; 6) passive venous congestion of the liver and kidneys; 7) fatty and granular liver dystrophy. The results of our study, the pathomorphological diagnosis of chlamydial infection in most of the cats that died was based on changes characteristic of interstitial pneumonia followed pneumosclerosis or fibrinous-purulent pleuropneumonia, with deep affection of the bronchial epithelium. Consequently, the features of chlamydial infection are such that the clinical picture does not always correspond to the severity of morphological manifestations and complications of infection. Weak clinical manifestations can be combined with significant destructive, degenerative and necrotic changes in organs and tissues.

The formation of an artificial vagina by Baldwin's method

1930 ◽  
Vol 26 (2) ◽  
pp. 218-218
Author(s):  
I. F. Kharitonov
Keyword(s):  
Small Intestine ◽  
Mucous Membrane ◽  
Satisfactory Result ◽  
Congenital Absence ◽  
Near Future ◽  
Artificial Vagina

Session 4 / XII 1929 Dr. I. F. Kharitonov (speaker Dr. A. N. Syzganov). The formation of an artificial vagina by Baldwin's method with a completely satisfactory result for the near future was produced by the operator in one case of congenital absence of this organ; the method is not safe, fraught with complications; in the reported case, the mucous membrane of the newly formed vagina continues to secrete juice from the small intestine, which strongly irritates the surrounding tissues.

scholarly journals Effect of a cocoa diet on the small intestine and gut-associated lymphoid tissue composition in an oral sensitization model in rats

2017 ◽  
Vol 42 ◽  
pp. 182-193 ◽  
Author(s):  
Mariona Camps-Bossacoma ◽  
Francisco J. Pérez-Cano ◽  
Àngels Franch ◽  
Eva Untersmayr ◽  
Margarida Castell
Keyword(s):  
Small Intestine ◽  
Lymphoid Tissue ◽  
Tissue Composition

scholarly journals Intestinal epithelial dysplasia

2020 ◽  
pp. 91-94
Author(s):  
T. E. Taranushenko ◽  
E. M. Vasilyeva ◽  
E. V. Antsiferova ◽  
L. N. Karpova ◽  
Y. S. Shamova
Keyword(s):  
Small Intestine ◽  
Rare Disease ◽  
Histological Examination ◽  
Mucous Membrane ◽  
Clinical Case ◽  
Clinical Presentation ◽  
Epithelial Dysplasia ◽  
Intestinal Epithelial ◽  
Electronic Microscopy

The article presents a clinical case of intestinal epithelial dysplasia (tufting enteropathy), a rare disease which relates to congenital diarrheas, has a particular clinical presentation and is life-threating. The diagnosis was confirmed by histological examination and electronic microscopy of mucous membrane of small intestine. Additional evidence is substantiated for the existence of prenatal markers of intestinal epithelial dysplasia represented as polyhydramnios and intrauterine dilatation of fetal intestinal loops. These symptoms are considered to be a clinical hallmark of sodium and chloride diarrheas and are described in single cases in enteropathy called a microvillus inclusion disease.

scholarly journals COMPARISON OF THE STATE OF THE MAXILLARY SINUSES IN A NEW CORONAVIRUS INFECTION COVID-19 AND ACUTE RESPIRATORY VIRAL INFECTION

2021 ◽  
Vol 14 (5) ◽  
pp. 28-33
Author(s):  
ALEXANDER V. KOLSANOV ◽  
◽  
TATYANA JU. VLADIMIROVA ◽  
PAVEL V. ZELTER ◽  
OLESYA V. ZELYOVA ◽  
...  
Keyword(s):  
Mucous Membrane ◽  
Paranasal Sinuses ◽  
Chronic Sinusitis ◽  
Respiratory Infections ◽  
Control Group ◽  
Acute Respiratory Infections ◽  
Lower Wall ◽  
Study Results ◽  
Coronavirus Infection ◽  
Maxillary Sinuses

The aim of the study was to identify possible changes in the maxillary sinuses during new coronavirus infection in comparison with the changes in the sinuses occurring during acute respiratory infections and to correlate the gender structure of the study groups. Material and methods. The study included 40 patients (18 women and 22 men) with a confirmed new coronavirus infection, hospitalized at the Covid Hospital Clinics of Samara State Medical University in 2020. All patients underwent multispiral computed tomography of the paranasal sinuses on a Ge revolution Evo 128 tomograph on the 10th day after the appearance of the first clinical symptoms. We also examined a control group of patients with acute respiratory infections with similar complaints of impaired sense of smell, rhinorrhea, and upper maxillary sinus discomfort. This group also included 40 people (24 women and 16 men). Statistical processing of the study results was performed using Microsoft Excel software package, the Mann – Whitney method of statistical significance calculation was used. Results and discussions. In 18 (45%) patients with a confirmed new coronavirus infection, a slight mucosal thickening along the lower wall of the maxillary sinuses was found symmetrically on both sides. Six (15%) of them were women and 12 (30%) were men. The age of the examined patients ranged from 31 to 83 years. Chronic sinusitis was noted in the history of 8 (20%) of the examined patients. In 6 (15%) patients with chronic sinusitis no abnormalities were detected in the maxillary sinuses at the time of examination. Two of them had parietal thickening of the mucous membrane along the lower wall of the maxillary sinuses. In the control group, there was significant symmetric parietal thickening of the mucous membrane of the paranasal sinuses in 24 (60%) examined patients (14 women and 10 men). There were no statistically significant differences in the prevalence of changes in the studied and control groups. Conclusion. According to the results of this study, there were no data on the pattern of occurrence of changes in the mucosa of the maxillary sinuses in new coronavirus infection with gender background or the presence of chronic inflammation of the maxillary sinuses in the history compared with the control group of examined patients after acute respiratory infections.

Determination of the fat content in the pancreas and mucous membrane (mucosa) of the small intestine of pigs

1979 ◽  
Vol 13 (5) ◽  
pp. 546-548
Author(s):  
V. P. Pakhomov ◽  
N. N. Evgrafova ◽  
V. T. Sapleva
Keyword(s):  
Small Intestine ◽  
Mucous Membrane ◽  
Fat Content

Immune disorders of the gastrointestinal tract

2010 ◽  
pp. 2244-2256
Author(s):  
D.J. Unsworth
Keyword(s):  
Small Intestine ◽  
Gastrointestinal Tract ◽  
B Lymphocytes ◽  
Lamina Propria ◽  
Thoracic Duct ◽  
Lymphoid Tissue ◽  
Plasma Cells ◽  
Immunoglobulin A ◽  
Systemic Circulation ◽  
Lymphoid Follicles

The gastrointestinal tract is protected by gut-associated lymphoid tissue that provides an environment where interaction occurs between luminal antigen and specially adapted immune tissue in Peyer’s patches (small intestine only) or lymphoid follicles. T and B lymphocytes primed in the gut migrate into the systemic circulation via the thoracic duct but home preferentially to the lamina propria of the intestine. Plasma cells of the lamina propria secrete immunoglobulin A as a dimer linked by a joining peptide....

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